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Dominic J Culligan
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Journal Articles

Impact of Cytogenetics, Induction Chemotherapy and MRD on Outcomes of Intensively Treated AML with KMT2A Rearrangements - Experience from UK NCRI AML17 and AML19

Jad Othman, Nicola Potter, Sylvie D Freeman, Nicholas McCarthy, Jelena Jovanovic, Manohursingh Runglall, Joanna Canham, Ian Thomas, Sean Johnson, Jamie Cavenagh, Panagiotis Kottaridis, David Taussig, Claire Arnold, Claire Hemmaway, Dominic J. Culligan, Ulrik Malthe Overgaard, Alan K. Burnett, Mike Dennis, Richard Dillon, Nigel H. Russell
Journal: Blood
Blood (2024) 144 (Supplement 1): 845.
https://doi.org/10.1182/blood-2024-201097
Published: 2024
Journal Articles

Glofitamab and Epcoritamab in the Real World: A UK Multicentre Retrospective Analysis of Efficacy, Tolerability and Practical Implications

Euan Haynes, Kushani Ediriwickrema, Sarah Lawless, Kevin Joyce, Matthew Wells, Jeffrey Smith, Kim Linton, Anna Santarsieri, George Follows, John Willan, Robert Osborn, Matthew R Wilson, Pamela McKay, Mahina Baloch, Rory McCulloch, Mary Gleeson, David Wrench, David Foldes, Edward Kanfer, Kyaw Zin Maw, Andrea Kuhnl, Matthew Ahearne, Mary Owen, Jane Norman, Ravindu De Silva, Nimish Shah, Harriet Ambrose, Christopher P. Fox, Janine Qasim, Graham P. Collins, Martha Vickers, David Tucker, Li Yuan Chan, Sunil Iyengar, Dima el-Sharkawi, Rebecca Auer, Catherine Cox, Hwai Jing Hiew, Andrew J. Davies, Philippa Kelsey, David John Lewis, Abigail Martin, Gavin Preston, Dominic J. Culligan, Angus Broom, William Wilson, Wendy Osborne, William Townsend
Journal: Blood
Blood (2024) 144 (Supplement 1): 3100.
https://doi.org/10.1182/blood-2024-203781
Published: 2024
Journal Articles

Replacing Procarbazine with Dacarbazine in Escalated Beacopp Dramatically Reduces the Post Treatment Haematopoietic Stem and Progenitor Cell Mutational Burden in Hodgkin Lymphoma Patients with No Apparent Loss of Clinical Efficacy

Anna Santarsieri, Emily Mitchell, Katherine Sturgess, Pauline Brice, Tobias F. Menne, Wendy Osborne, Thomas Creasey, Kirit M. Ardeshna, Sarah Behan, Kaljit Bhuller, Stephen Booth, Nikesh D. Chavda, Graham P. Collins, Dominic J. Culligan, Kate Cwynarski, Andrew Davies, Abigail Downing, David Dutton, Michelle Furtado, Eve Gallop-Evans, Andrew Hodson, David Hopkins, Hannah Hsu, Sunil Iyengar, Stephen G. Jones, Kim M. Linton, Oliver C. Lomas, Nicolas Martinez-Calle, Abhinav Mathur, Pamela McKay, Sateesh K. Nagumantry, Deirdre O'Mahony, Elizabeth H. Phillips, Neil Phillips, John F. Rudge, Nimish K. Shah, Gwyneth Stafford, Alex Sternberg, Rachel Trickey, Benjamin J. Uttenthal, Natasha Wetherall, Andrew K. McMillan, Michael Stratton, Elisa Laurenti, Peter J. Campbell, George A. Follows
Journal: Blood
Blood (2022) 140 (Supplement 1): 1761–1764.
https://doi.org/10.1182/blood-2022-166543
Published: 2022
Journal Articles

Management of MDS with Isolated Del(5q) Patients in the European MDS (EUMDS) Registry: A Report on 197 Cases

Inga Mandac Smoljanovic, Adele Taylor, Pierre Fenaux, Agnès Guerci-Bresler, Raphael Itzykson, Argiris Symeonidis, Ioannis Kotsianidis, Moshe Mittelman, Guillermo Sanz, Dominic J. Culligan, Jaroslav Cermak, Reinhard Stauder, Eva Hellström-Lindberg, Luca Malcovati, Saskia M.C. Langemeijer, Ulrich Germing, Krzysztof Madry, Howard S. Oster, Alexandra Smith, Corine van Marrewijk, Theo M de Witte, David Bowen
Journal: Blood
Blood (2022) 140 (Supplement 1): 9802–9803.
https://doi.org/10.1182/blood-2022-167716
Published: 2022
Journal Articles

Management of MDS with Isolated Del(5q) Patients in the European MDS (EUMDS) Registry, a Unique Prospective Real-World Dataset

David Bowen, Adele Taylor, Pierre Fenaux, Agnes Guerci-Bresler, Raphael Itzykson, Argiris Symeonidis, Ioannis Kotsianidis, Moshe Mittelman, Guillermo Sanz, Dominic J. Culligan, Jaroslav Cermak, Reinhard Stauder, Eva Hellstrom Lindberg, Luca Malcovati, Saskia M. C. Langemeijer, Ulrich Germing, Howard S. Oster, Krzysztof Madry, Mette Skov Holm, Alexandra Smith, Corine van Marrewijk, Theo M de Witte
Journal: Blood
Blood (2021) 138 (Supplement 1): 4671.
https://doi.org/10.1182/blood-2021-150322
Published: 2021
Journal Articles

A Phase 1b Study of Eltrombopag and Azacitidine in Patients with High Risk Myelodysplastic Syndromes and Related Disorders

Alex Sternberg, MRCP,FRCPath, Rebecca H. Boucher, BSc, MSc, PhD, Helen C Coulthard, BSc, Manoj Raghavan, MBBS, PhD MRCP, FRCPath, Dominic J. Culligan, MD, Aimee Jackson, BSc, MSc, Catherine Cargo, MB, PhD, Mike Dennis, MD, Marlen Metzner, MSc, Rachel Moore, BA, David Bowen, MD, Paresh Vyas, MRCP, FRCP, FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-134227
Published: 2020
Journal Articles

A Phase I/II Dose-Escalation Study of Thiotepa-Based Immunochemotherapy in Relapsed/Refractory Primary Central Nervous System Lymphoma; The Tier Trial

Christopher P Fox, MBChB(Hons), MRCP, FRCPath, PhD, Ayesha S Ali, MSc, Dorothee Auer, MD DM, PhD, Steffi Thust, MD FRCR, Aimee E Jackson, MSc, Louise Hopkins, BSc, MRes, Catherine Thomas, PhDBSc, Nicolas Martinez-Calle, MD MSc, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Shireen Kassam, MD, Josh Wright, MD, David Lewis, PhD FRCPath, BSc, Andres JM Ferreri, MD, Sridhar Chaganti, MDPhDMRCP,FRCPath, Jeffery Smith, MBChB BMedSci MRCP FRCPath, Kim Linton, MBChB PhD, Ian Chau, MD, Dominic J. Culligan, MD, Andrew Davies, MD PhD, Roderick Johnson, MD, Kate Cwynarski, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2879.
https://doi.org/10.1182/blood-2019-122830
Published: 2019
Journal Articles

Elevated Labile Plasma Iron (LPI) Levels in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Are Associated with Decreased Quality of Life and Reduced Survival

Marlijn Hoeks, MD, Tim Bagguley, MS, Rian Roelofs, Msc, Louise De Swart, MD, David Bowen, MD PhD, Argiris Symeonidis, MD PhD, Corine van Marrewijk, PhD, Eva Hellström-Lindberg, MD PhD, Aurelia Tatic, MD, Saskia Langemeijer, MD PhD, Dominic J. Culligan, Marian Macheta, MD, Hege Garelius, MD, Michail Spanoudakis, MD, Sally Killick, MD, Panagiotis Panagiotidis, MD PhD, Oana Stanca Ciocan, MD, Juliet Mills, MD, Bryson Pottinger, Sam Ackroyd, MD, Claire Hall, MD, Jackie Droste, PhD, Alexandra Smith, PhD, Dorine W. Swinkels, MD PhD, Theo M de Witte, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4392.
https://doi.org/10.1182/blood-2018-99-118070
Published: 2018
Journal Articles

Results of a Phase 2 Trial of the Monocyte-Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) in Chronic Myelomonocytic Leukemia (CMML) — the UK Monocle Study

Steven Knapper, DM, Michael Dennis, MD, MRCP, FRCPath, Mark W Drummond, PhDMD, Robert K. Hills, MA, DPhil, MSc, Richard James Dillon, MA, PhD MRCP, FRCPath, Christopher Pocock, MD PhD, Dominic J. Culligan, Paresh Vyas, Daniel Wiseman, MB, ChB, Joanna Zabkiewicz, PhD, Marie Hodges, PhD MSc, Catherine Cargo, MB, FRCPath, Jan Taylor, PhD MSc, BSc, Laura Upton, Melissa Wright, David Bowen, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1818.
https://doi.org/10.1182/blood-2018-99-110356
Published: 2018
Journal Articles

No Added Benefit of Eight Versus Six Cycles of CHOP When Combined with Rituximab in Previously Untreated Diffuse Large B-Cell Lymphoma Patients: Results from the International Phase III GOYA Study

Laurie H Sehn, MDMPH, Angela Giovanna Congiu, Dominic J. Culligan, Mercedes Gironella, Dok Hyun Yoon, Michinori Ogura, Andras Rosta, Jun Zhu, Aino Launonen, Tina Nielsen, Gila Sellam, Marek Trněný, Umberto Vitolo, Maurizio Martelli
Journal: Blood
Blood (2018) 132 (Supplement 1): 783.
https://doi.org/10.1182/blood-2018-99-116845
Published: 2018
Journal Articles

Real-World Outcomes of Older Patients with Primary Central Nervous System Lymphoma (PCNSL): Methotrexate Dose Intensity and Combination with Cytarabine Correlate with Response and Survival

Nicolas Martinez-Calle, MD #, Edward Poynton, Alia Alchawaf, MD, Shireen Kassam, MD, Matthew Horan, MD, Mark Rafferty, MBBS, BSc, Phillipa Kelsey, MD, Gemma Scott, MD, Stephanie Bruce, MD, Hannah Buckley, MD, Sophie Jones, MD, Yeong Jer Lim, MD, Ngu Loretta, MD, David Lewis, MD, Thankamma Ajithkumar, MD, Dominic J. Culligan, Clare Rowntree, MD, Josh Wright, MD, Pamela McKay, MD, Samih Fourali, MD, Toby A. Eyre, Jeffrey Smith, MD, Wendy Osborne, MD, Deborah Yallop, MBBS FRCP FRCPath PhD, Kim Linton, MBChB PhD, Christopher P. Fox, MD PhD, Kate Cwynarski, MD PhD # (#Shared authorship)
Journal: Blood
Blood (2018) 132 (Supplement 1): 572.
https://doi.org/10.1182/blood-2018-99-111901
Published: 2018
Journal Articles

Elevated Labile Plasma Iron Levels (LPI) and Increased Oxidative Stress Are Associated with Red Blood Cell Transfusions in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Subtitle: from the European Leukemianet MDS Registry

Marlijn Hoeks, MD, Saskia Langemeijer, MD PhD, Louise De Swart, MD, Tim Bagguley, Corine van Marrewijk, PhD, David Bowen, MD PhD, Jaroslav Cermak, Eva Hellstrom-Lindberg, MD PhD, Aurelia Tatic, MD, Argiris Symeonidis, Marian G.J. Van Kraaij, MD PhD, Panagiotis Panagiotidis, Hege Garelius, MD, Dominic J Culligan, Marta Krejci, MD PhD, Jackie Droste, PhD, Alexandra Smith, PhD, Dorine W. Swinkels, MD PhD, Theo de Witte, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4327.
https://doi.org/10.1182/blood.V128.22.4327.4327
Published: 2016
Journal Articles

Exome Sequencing and Linkage Analysis Implicates Two Candidate Genes On Chromosome 3p in Familial Hodgkin Lymphoma

Alastair Lawrie, Timothee Cezard, Dominic J Culligan, Mark A Vickers
Journal: Blood
Blood (2012) 120 (21): 53.
https://doi.org/10.1182/blood.V120.21.53.53
Published: 2012
Journal Articles

Local and systemic induction of CD4 + CD25 + regulatory T-cell population by non-Hodgkin lymphoma

Sajjan Mittal, Neil A. Marshall, Linda Duncan, Dominic J. Culligan, Robert N. Barker, Mark A. Vickers
Journal: Blood
Blood (2008) 111 (11): 5359–5370.
https://doi.org/10.1182/blood-2007-08-105395
Published: 2008
Includes: Supplemental data
Journal Articles

Transmission of Chromosomally Integrated HHV6 by Allogeneic Peripheral Blood Stem Cell Transplantation Associated with the Development of a Fatal Macrophage Activation (Haemophagocytic) Syndrome.

Mark Crowther, MD, Pamela Molyneaux, MD, William F. Carman, MD, Kate N. Ward, MD, Dominic J. Culligan, MD
Journal: Blood
Blood (2006) 108 (11): 5278.
https://doi.org/10.1182/blood.V108.11.5278.5278
Published: 2006
Journal Articles

Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma

Neil A. Marshall, Linsey E. Christie, Laura R. Munro, Dominic J. Culligan, Peter W. Johnston, Robert N. Barker, Mark A. Vickers
Journal: Blood
Blood (2004) 103 (5): 1755–1762.
https://doi.org/10.1182/blood-2003-07-2594
Published: 2004