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Journal Articles

Do We Still Need to Perform Bone Marrow Examination in All Subjects Suspected of MDS? Evaluation and Validation of Non-Invasive (Web-Based) Algorithm

Howard S Oster, Ariel M Polakow, Noa Goldschmidt, Moshe Mittelman
Journal: Blood
Blood (2023) 142 (Supplement 1): 6475.
https://doi.org/10.1182/blood-2023-178713
Published: 2023
Journal Articles

Management of MDS with Isolated Del(5q) Patients in the European MDS (EUMDS) Registry: A Report on 197 Cases

Inga Mandac Smoljanovic, Adele Taylor, Pierre Fenaux, Agnès Guerci-Bresler, Raphael Itzykson, Argiris Symeonidis, Ioannis Kotsianidis, Moshe Mittelman, Guillermo Sanz, Dominic J. Culligan, Jaroslav Cermak, Reinhard Stauder, Eva Hellström-Lindberg, Luca Malcovati, Saskia M.C. Langemeijer, Ulrich Germing, Krzysztof Madry, Howard S. Oster, Alexandra Smith, Corine van Marrewijk, Theo M de Witte, David Bowen
Journal: Blood
Blood (2022) 140 (Supplement 1): 9802–9803.
https://doi.org/10.1182/blood-2022-167716
Published: 2022
Journal Articles

Erythropoietin Administration Delays B Cell Maturation and Promotes B Cell to Erythroid Transdifferentiation in Mice

Albert Kolomansky, Anton Gorodov, Stav Kislev, Nathalie Ben-Califa, Alana Starr, Yankel Gabet, Martina Rauner, Ben Wielockx, Moshe Mittelman, Howard S. Oster, Drorit Neumann
Journal: Blood
Blood (2022) 140 (Supplement 1): 1241–1242.
https://doi.org/10.1182/blood-2022-167848
Published: 2022
Journal Articles

Can We Identify Individuals at Risk to Develop Multiple Myeloma? a Machine Learning Based Predictive Model

Moshe Mittelman, Howard S. Oster, Yatir Ben Shlomo, Ariel Israel, Osnat Jarchowcky Dolberg, Samah Hayek, Michael Leshchinsky, Eldad Kepten, Ran Balicer, Galit Shaham
Journal: Blood
Blood (2022) 140 (Supplement 1): 7259–7260.
https://doi.org/10.1182/blood-2022-162438
Published: 2022
Journal Articles

Validation of a Novel Algorithm with a High Specificity in Ruling out MDS

Felicitas Schulz, Kathrin Nachtkamp, Howard S. Oster, Moshe Mittelman, Norbert Gattermann, Carmen Barthuber, Sarah Schweier, Ulrich Germing
Journal: Blood
Blood (2022) 140 (Supplement 1): 9789–9790.
https://doi.org/10.1182/blood-2022-163431
Published: 2022
Journal Articles

Effectiveness of the BNT162b2mRNA COVID-19 vaccine in patients with hematological neoplasms in a nationwide mass vaccination setting

Clinical Trials & Observations
Moshe Mittelman, Ori Magen, Noam Barda, Noa Dagan, Howard S. Oster, Avi Leader, Ran Balicer
Journal: Blood
Blood (2022) 139 (10): 1439–1451.
https://doi.org/10.1182/blood.2021013768
Published: 2022
Includes: Supplemental data
Journal Articles

Management of MDS with Isolated Del(5q) Patients in the European MDS (EUMDS) Registry, a Unique Prospective Real-World Dataset

David Bowen, Adele Taylor, Pierre Fenaux, Agnes Guerci-Bresler, Raphael Itzykson, Argiris Symeonidis, Ioannis Kotsianidis, Moshe Mittelman, Guillermo Sanz, Dominic J. Culligan, Jaroslav Cermak, Reinhard Stauder, Eva Hellstrom Lindberg, Luca Malcovati, Saskia M. C. Langemeijer, Ulrich Germing, Howard S. Oster, Krzysztof Madry, Mette Skov Holm, Alexandra Smith, Corine van Marrewijk, Theo M de Witte
Journal: Blood
Blood (2021) 138 (Supplement 1): 4671.
https://doi.org/10.1182/blood-2021-150322
Published: 2021
Journal Articles

Patients Diagnosed with Myelodysplastic Syndromes Display Lower Bone Mass: Assessment Using Bone Marrow Biopsies Manually and with Artificial Intelligence

Albert Kolomansky, Roy Malka, Edo Cohen-Karlik, Gal Barequet, Sagi Tauber, Itay Kalev, Ruben Wolhandler, Yoav Gaulan, Roee Esquira, Moni Shahar, Yishai Mansour, Amir Globerson, Drorit Neumann, Moshe Mittelman, Howard S. Oster
Journal: Blood
Blood (2021) 138 (Supplement 1): 3694.
https://doi.org/10.1182/blood-2021-149575
Published: 2021
Journal Articles

Quality of Life Is Impaired in Anemic MDS Patients, and May Still Remain Poor Even When Hemoglobin Improves

Yael Haring, Nitzan Cohen Sagy, Shaimaa Taha, Albert Kolomansky, Howard S. Oster, Moshe Mittelman
Journal: Blood
Blood (2021) 138 (Supplement 1): 3698.
https://doi.org/10.1182/blood-2021-148627
Published: 2021
Journal Articles

Anti-CD20-Mediated B Cell Depletion Is Associated with Reduced Osteoclastogenic Signals and Bone Mass Preservation: Clinical Observation in Patients with Follicular Lymphoma Supplemented By Animal Studies in a Murine Model

Albert Kolomansky, MD, Irit Kay, MD, Nathalie Ben-Califa, PhD, Anton Gorodov, BSc, Zamzam Awida, BSc, Ofer Sadovnic, MD, Maria Ibrahim, BSc, Tamar Liron, PhD, Sahar Hiram-Bab, PhD, Howard S. Oster, MD PhD, Nadav Sarid, MD, Chava Perry, MD PhD, Yankel Gabet, DMD, PhD, Moshe Mittelman, MD, Drorit Neumann, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13.
https://doi.org/10.1182/blood-2020-142295
Published: 2020
Journal Articles

B Cell Specific Knockdown of the Erythropoietin (EPO) Receptor Attenuates EPO-Induced Bone Loss in Mice

Albert Kolomansky, MD, Naamit Deshet-Unger, PhD, Nathalie Ben-Califa, PhD, Zamzam Awida, Maria Ibrahim, B.Sc., Tamar Liron, PhD, Sahar Hiram-Bab, PhD, Howard S. Oster, MD PhD, Moshe Mittelman, MD, Martina Rauner, PhD, Ben Wielockx, PhD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 939.
https://doi.org/10.1182/blood-2019-127092
Published: 2019
Journal Articles

MDS Diagnosis: Many Patients May Not Require Bone Marrow Examination

Howard S. Oster, MD PhD, Simon Crouch, MSc, PhD, Alexandra Smith, PhD, Ge Yu, MSc, Bander Abu Shrkihe, MD, Shoham Baruch, Albert Kolomansky, MD, Jonathan Ben-Ezra, MD, Shachar Naor, MD, Pierre Fenaux, MD PhD, Argiris Symeonidis, MD PhD, Reinhard Stauder, MD MSc, Jaroslav Cermak, MD PhD, Guillermo Sanz, Eva Hellström-Lindberg, MD PhD, Luca Malcovati, MD, Saskia Langemeijer, MD PhD, Ulrich Germing, MD, Mette Skov Holm, MD PhD, Krzysztof Madry, Agnes Guerci-Bresler, MD, Dominic Culligan, MD, Laurence Sanhes, MD, Juliet Mills, MD, Ioannis Kotsianidis, PhD, Corine van Marrewijk, PhD, David Bowen, MD PhD, Theo de Witte, MD PhD, Moshe Mittelman, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4357.
https://doi.org/10.1182/blood-2018-99-111838
Published: 2018
Journal Articles

Erythropoietin (EPO) Regulates Bone Mass Via EPO Receptors on Myeloid and Lymphocytic Cells

Sahar Hiram-Bab, PhD, Albert Kolomansky, MD, Naamit Deshet-Unger, PhD, Nathalie Ben-Califa, PhD, Tamar Liron, PhD, Martina Rauner, PhD, Ben Wielockx, PhD, Moshe Mittelman, MD, Howard S. Oster, MD PhD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 846.
https://doi.org/10.1182/blood-2018-99-111643
Published: 2018
Journal Articles

Depletion of Mature B Cells By Anti CD20-Directed Antibody Induces Trabecular Bone Loss in Young Mice: An Alert for Clinicians?

Albert Kolomansky, MD, Naamit Deshet-Unger, PhD, Alina Ostrovsky, Nathalie Ben-Califa, PhD, Sahar Hiram-Bab, PhD, Tamar Liron, PhD, Howard S. Oster, MD PhD, Moshe Mittelman, MD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5642.
https://doi.org/10.1182/blood.V130.Suppl_1.5642.5642
Published: 2017
Journal Articles

Can We Diagnose MDS without Bone Marrow Examination? a Proposed EUMDS-Based Non-Invasive Diagnostic Model

Howard S. Oster, MD PhD, Bander Abu Shrkihe, MD, Simon Crouch, MSc, PhD, Alexandra Smith, PhD, Ge Yu, PhD, Gal Carmi, MD, Jonathan Ben-Ezra, MD, Shachar Naor, MD, Pierre Fenaux, MD PhD, Argiris Symeonidis, MD PhD, Reinhard Stauder, MD, Jaroslav Cermak, MD PhD, Guillermo Sanz, MD, Eva Hellstrom-Lindberg, MD PhD, Luca Malcovati, MD, Saskia Langemeijer, MD PhD, Ulrich Germing, MD, Mette Skov Holm, MD PhD, Krzysztof Madry, MD PhD, Aurelia Tatic, MD, Antonio Medina de Almeida, MD PhD, Aleksandar Savic, MD PhD, Njetočka Gredelj-Šimec, MD, Agnes Guerci Bresler, Corine van Marrewijk, PhD, David T. Bowen, MD, T. M. M de Witte, MD PhD, Moshe Mittelman, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2975.
https://doi.org/10.1182/blood.V130.Suppl_1.2975.2975
Published: 2017
Journal Articles

Transdifferentiation of Bone Marrow Pro-B Cells into Bone-Resorbing Osteoclasts- an Unexpected Role for Erythropoietin

Naamit Deshet-Unger, MSc, Sahar Hiram-Bab, PhD, Nathalie Ben-Califa, PhD, Dafna Gilboa, MSc, Tamar Liron, PhD, Kolomansky Albert, MD, Howard S Oster, MD PhD, Moshe Mittelman, MD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD
Journal: Blood
Blood (2016) 128 (22): 5043.
https://doi.org/10.1182/blood.V128.22.5043.5043
Published: 2016
Journal Articles

An Active Intervention Has Reduced RBC Transfusion Number: A Single Center Expierience

Ilya Kirgner, MD, Mara Hareuveni, PhD, Yael Sagy, PhD, Ahuva Weiss-Meilik, PhD, Howard S Oster, MD PhD, Irit Avivi, MD, Gabriel Barabash, MD, Moshe Mittelman, MD
Journal: Blood
Blood (2016) 128 (22): 5040.
https://doi.org/10.1182/blood.V128.22.5040.5040
Published: 2016
Journal Articles

Immune Dysfunction in Patients with MDS Is Partially Corrected in EPO-Treated Patients: Differences According to WHO Classification

Howard S Oster, MD PhD, Naamit Deshet-Unger, MSc, Drorit Neumann, PhD, Moshe Mittelman, MD, Nir Maaravi, MD, Sara Prutchi-Sagiv, PhD, Golishevski Nataliya, MD
Journal: Blood
Blood (2016) 128 (22): 3165.
https://doi.org/10.1182/blood.V128.22.3165.3165
Published: 2016
Journal Articles

Recombinant Erythropoietin and Darbepoetin Alpha Exert a Similar Dose-Dependent Osteopenic Effect Which May Advocate for "Start Low, Go Slow" Dosing Strategy in Clinical Practice

Kolomansky Albert, MD, Sahar Hiram-Bab, PhD, Naamit Deshet-Unger, MSc, Nathalie Ben-Califa, PhD, Dafna Gilboa, MSc, Tamar Liron, PhD, Howard S Oster, MD PhD, Moshe Mittelman, MD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD
Journal: Blood
Blood (2016) 128 (22): 2445.
https://doi.org/10.1182/blood.V128.22.2445.2445
Published: 2016
Journal Articles

Erythropoietin May Affect B-Cell Maturation and Plasma Cell Antibody Production in Mice

Howard S Oster, MD PhD, Naamit Deshet-Unger, MS, Max Gassmann, DVM, Moshe Mittelman, MD, Drorit Neumann, PhD
Journal: Blood
Blood (2015) 126 (23): 4620.
https://doi.org/10.1182/blood.V126.23.4620.4620
Published: 2015