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Journal Articles

Thrombolytic Therapy for Venous Thromboembolism in the Pediatric Population: A Systematic Review and Meta-Analysis

Hassan Kawtharany, Muayad Azzam, Paul Monagle, Rachel S. Bercovitz, Aseel Alkhader, Qais Hamarsha, Hadi Khaled Abou Zeid, Razan Mansour, Carine Tabak, Payal Patel, Sarah Lamat Baghdadi, Marisol Betensky, Rukhmi Bhat, Tina Biss, Brian R. Branchford, Leonardo R. Brandao, Anthony K C Chan, E. Vincent Faustino, Julie Jaffray, Sophie Jones, Bryce Kerlin, Nicole Kucine, Riten Kumar, Christoph Male, Marie-Claude Pelland-Marcotte, Leslie Raffini, Chittalsinh M Raulji, Sarah E Sartain, Clifford M. Takemoto, Cristina Tarango, Heleen Van Ommen, Maria C Velez, Sara Vesely, John Wiernikowski, Suzan Williams, Hope P. Wilson, Gary Woods, Ayesha Zia, Reem A Mustafa
Journal: Blood
Blood (2024) 144 (Supplement 1): 2633.
https://doi.org/10.1182/blood-2024-212166
Published: 2024
Journal Articles

Clinical Outcomes over 2 Years of Once-Weekly Efanesoctocog Alfa Treatment in Children with Severe Hemophilia A: Second Interim Analysis from the Phase 3 XTEND-ed Long-Term Extension Study

Lynn Malec, Beatrice Nolan, Anthony K C Chan, Manuela Albisetti, Sheng-Chieh Chou, Bulent Zulfikar, Mindy Simpson, Liqi Feng, Helena Palmborg, Graham Neill, Lydia Abad-Franch, Sriya Gunawardena, Karin Fijnvandraat
Journal: Blood
Blood (2024) 144 (Supplement 1): 5495.
https://doi.org/10.1182/blood-2024-206915
Published: 2024
Journal Articles

Patient and Clinical Experience on Concizumab Clinical Trial: A Case Study

Karen Strike, Mihir Bhatt, Nessa Chan, Nasrin Samji, Kay Decker, Rebecca Goldsmith, Anthony K C Chan
Journal: Blood
Blood (2024) 144 (Supplement 1): 5494.
https://doi.org/10.1182/blood-2024-209470
Published: 2024
Journal Articles

In Vitro Drug Profiling to Guide Treatment for Relapse/Refractory AML

Stephen Lam, Andrew Chung-Hin Poon, Koon C. Chan, Navrose Kaur Singh, Wing Lam, Ching-Man Wong, Chi Yeung Fung, Wing-Hei Lai, Ka Lam Nelson K. L. Ng, Anskar Y.H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 3603.
https://doi.org/10.1182/blood-2024-209746
Published: 2024
Journal Articles

Investigating the Impact of FIX Fc Fusion on Its Extravascular Distribution and Hemostatic Properties

Bonnie Chu, Michela Ronconi, Hasam Madarati, Colin Kretz, Peter L. Gross, Anthony K C Chan, Davide Matino
Journal: Blood
Blood (2024) 144 (Supplement 1): 2576.
https://doi.org/10.1182/blood-2024-193406
Published: 2024
Journal Articles

Combination of Quizartinib and Omacetaxine Mepesuccinate (QUIZOM) As an Effective Treatment Remodels Proteostasis and Triggers Inflammatory Response in FLT3-ITD AML

Stephen Lam, Li-Chuan Zheng, Kelvin K.W. Wong, Man Kit Garret Leung, Chenqinyao Li, Kwui-Wa Tong, Wing Lam, Xiao-yuan Zheng, Koon C. Chan, Natalie Nok-Man Chan, Ka Lam Nelson K. L. Ng, Chee Chean Dang, Tsz-Ho Kwok, Sze Pui Tsui, Rakesh Sharma, Jason W.H. Wong, Suet Yi Leung, Cheuk-Him Man, Anskar Y.H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 1510.
https://doi.org/10.1182/blood-2024-209860
Published: 2024
Journal Articles

Annualized Bleeding Rates in Patients with Hemophilia a or B and Inhibitors with and without Target Joints at Baseline: Results from the Concizumab Phase 3 Explorer7 Study

Amy D. Shapiro, Shashikant Apte, Ana Boban, Renée Brown Frandsen, Silvia Linari, Johnny Mahlangu, Camila Martins Mazini Tavares, Tadashi Matsushita, Salim Nekkal, Jameela Sathar, Anthony K C Chan
Journal: Blood
Blood (2024) 144 (Supplement 1): 715.
https://doi.org/10.1182/blood-2024-209759
Published: 2024
Journal Articles

Anticoagulation Therapy for Venous Thromboembolism in the Pediatric Population: A Systematic Review and Meta-Analysis

Muayad Azzam, Hassan Kawtharany, Paul Monagle, Rachel S. Bercovitz, Qais Hamarsha, Aseel Alkhader, Hadi Khaled Abou Zeid, Razan Mansour, Payal Patel, Carine Tabak, Sarah Lamat Baghdadi, Marisol Betensky, Rukhmi Bhat, Tina Biss, Brian R. Branchford, Leonardo R. Brandao, Anthony K C Chan, E. Vincent Faustino, Julie Jaffray, Sophie Jones, Bryce Kerlin, Nicole Kucine, Riten Kumar, Christoph Male, Marie-Claude Pelland-Marcotte, Leslie Raffini, Chittalsinh M Raulji, Sarah E Sartain, Clifford M. Takemoto, Cristina Tarango, Heleen Van Ommen, Maria C C. Velez-Yanguas, Sara Vesely, John Wiernikowski, Suzan Williams, Hope P. Wilson, Gary Woods, Ayesha Zia, Reem A Mustafa
Journal: Blood
Blood (2024) 144 (Supplement 1): 1257.
https://doi.org/10.1182/blood-2024-212150
Published: 2024
Journal Articles

Inhibition of Threonine Tyrosine Kinase Suppressed TP53- mutated Acute Myeloid Leukaemia Via Synergism with Venetoclax and Activation of the Cgas-Sting Pathway

Wing Lam, Koon C. Chan, Kwui-Wa Tong, Ka-Lam Ng, Mark R Bray, Tak-Wah Mak, Cheuk-Him Man, Anskar Y. H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 1399.
https://doi.org/10.1182/blood-2024-201920
Published: 2024
Journal Articles

Activation of Cgas-Sting Pathway By Hypomethylating Agent in TP53 Mutated MDS/AML

Ka Lam Nelson Ng, Lam Ng, Stephen Lam, Xingliang Liu, Koon C. Chan, Lichuan Zheng, Chunxiao Zhang, Rachel L. S. Tse, Wing Lam, Natalie Nok-Man Chan, Cheuk Him Man, Arthur K.L. Cheung, Ho-Wan Ip, Chun H. Au, Edmond Ma, Chi T. Ng, Ying Ni, Run S. Li, Guang Sheng Ling, Suet Yi Leung, Asif Javed, Anskar Y. H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 2726.
https://doi.org/10.1182/blood-2024-202769
Published: 2024
Journal Articles

New insights into the biology of T-cell lymphomas

Javeed Iqbal, Giorgio Inghirami, Wing C. Chan
Journal: Blood
Blood (2024) 144 (18): 1873–1886.
https://doi.org/10.1182/blood.2023021787
Published: 2024
Includes: Supplemental data
Journal Articles

Motive and opportunity: MYC rearrangements in high-grade B-cell lymphoma with MYC and BCL2 rearrangements (an LLMPP study)

Laura K. Hilton, Brett Collinge, Susana Ben-Neriah, Waleed Alduaij, Haya Shaalan, Andrew P. Weng, Manuela Cruz, Graham W. Slack, Pedro Farinha, Tomoko Miyata-Takata, Merrill Boyle, Barbara Meissner, James R. Cook, Sarah L. Ondrejka, German Ott, Andreas Rosenwald, Elias Campo, Catalina Amador, Timothy C. Greiner, Philipp W. Raess, Joo Y. Song, Giorgio Inghirami, Elaine S. Jaffe, Dennis D. Weisenburger, Wing C. Chan, Klaus Beiske, Kai Fu, Jan Delabie, Stefania Pittaluga, Javeed Iqbal, George Wright, Laurie H. Sehn, Kerry J. Savage, Andrew J. Mungall, Andrew L. Feldman, Louis M. Staudt, Christian Steidl, Lisa M. Rimsza, Ryan D. Morin, David W. Scott
Journal: Blood
Blood (2024) 144 (5): 525–540.
https://doi.org/10.1182/blood.2024024251
Published: 2024
Includes: Supplemental data
Journal Articles

Mechanistic Elucidation of the Tumor-Promoting Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 in B-Cell Receptor Signaling in Mantle Cell Lymphoma

Serene Xavier, Vivian Nguyen, Vishal Khairnar, An Phan, Lu Yang, Michael Nelson, Elizabeth Tseng, Aimin Li, Joo Y Song, Dennis D. Weisenburger, Wing C. Chan, Markus Müschen, Vu N. Ngo
Journal: Blood
Blood (2023) 142 (Supplement 1): 720.
https://doi.org/10.1182/blood-2023-175064
Published: 2023
Journal Articles

PRDM1 Promotes Primary Human Circulating CD56 dim NK-Cell Differentiation

Xuxiang Liu, Jibin Zhang, Yunfei Shi, Kunal Shetty, Can Kucuk, Esra Esmeray, Wing C. Chan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1177.
https://doi.org/10.1182/blood-2023-180323
Published: 2023
Journal Articles

Gene Expression Profiling Reveals Two Overarching Types of Anaplastic Large Cell Lymphoma with Distinct Targetable Biology: An L.L.M.P.P. Study

Andrew L. Feldman, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Naoki Oishi, Catalina Amador, Elias Campo, Wing C. Chan, James R. Cook, Jan Delabie, Pedro Farinha, Kai Fu, Timothy C. Greiner, Giorgio Inghirami, Javeed Iqbal, Elaine S. Jaffe, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Phil Raess, Andreas Rosenwald, Kerry J. Savage, Graham Slack, Susan L. Slager, Joo Y. Song, Louis M. Staudt, George Wright, Hao-Wei Wang, Yu Zeng, Tadashi Yoshino, Xiaojun Wu, Ryan A. Wilcox, Xueju Wang, Akira Satou, Anamarija M. Perry, Roberto Miranda, L. Jeffrey Medeiros, Matthew J. Maurer, Eric Mou, Young Hyeh Ko, Kennosuke Karube, Brad S. Kahl, Liuyan Jiang, David L Jaye, Laurence de Leval, Weina Chen, Jennifer R. Chapman-Fredricks, James R. Cerhan, Carlos Barrionuevo, Stephen M Ansell, Ahmed Aljudi
Journal: Blood
Blood (2023) 142 (Supplement 1): 847.
https://doi.org/10.1182/blood-2023-186969
Published: 2023
Journal Articles

The Influence of TET2 and/or DNMT3A Knockout on the 5hmC Levels and Growth Characteristics of Modified Human Primary CD4 T Cells after Activation

Ruimeng Yang, Xuxiang Liu, Jibin Zhang, Yuping Li, Krystie Chew, Claire Wu, Jasmine M. Zain, Joo Y. Song, Waseem Gul Lone, Javeed Iqbal, Wing C. Chan
Journal: Blood
Blood (2023) 142 (Supplement 1): 2775.
https://doi.org/10.1182/blood-2023-187176
Published: 2023
Journal Articles

Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T-Cell Lymphoma

Alyssa Bouska, Weiwei Zhang, Sunandini Sharma, Harald Holte, Ab Rauf Shah, Waseem Gul Lone, Luca Vincenzo Cappelli, Danilo Fiore, Qiang Gong, Tayla Heavican-Foral, Jeffrey Cannatella, Catalina Amador, Aiza Arif, Lynette Smith, Soon Thye Lim, Choon Kiat Ong, Andrew L. Feldman, Ming-Qing Du, Laurence de Leval, Timothy C. Greiner, Kai Fu, Gunhild Trøen, Daniel Vodak, Sigve Nakken, Jan Delabie, David M. Weinstock, Stefano A. Pileri, Antonella Laginestra, Kyeongjin Kim, Utpal Pajvani, Julie M. Vose, Dennis D Weisenburger, Sandeep Dave, Giorgio Inghirami, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2023) 142 (Supplement 1): 2993.
https://doi.org/10.1182/blood-2023-186530
Published: 2023
Journal Articles

Genomic Stability, DNA Repair and the SKP1-CUL1-F-Box Complex in HIV Associated Diffuse Large B-Cell Lymphoma

Lindsey Armitage, Sarah Gibson, Pedro S de Carvalho, Lee Wisner, Joo Y Song, Wing C. Chan, Jennifer R. Chapman-Fredricks, Francisco Vega, Stefano A. Pileri, Louis de Jager, Fabio E Leal, Lisa M. Rimsza, Alanna Maguire
Journal: Blood
Blood (2023) 142 (Supplement 1): 2991.
https://doi.org/10.1182/blood-2023-182953
Published: 2023
Journal Articles

Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies

Kadriye Nehir Cosgun, Mark E Robinson, Salim Oulghazi, Liang Xu, Gang Xiao, Lai N Chan, Jaewoong Lee, Kohei Kume, Etienne Leveille, David Fonseca Arce, Dhruv Khanduja, Niklas Feldhahn, Joo Y. Song, Wing C. Chan, Jianjun Chen, M. Mark Taketo, Hilde Schjerven, Julia Jellusova, Shalin Kothari, Matthew S Davids, Markus Müschen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2818.
https://doi.org/10.1182/blood-2023-190522
Published: 2023
Journal Articles

Refining Diagnostic Subtypes of Peripheral T-Cell Lymphoma Using a Multiparameter Approach

Catalina Amador, Dennis D Weisenburger, Ana Gomez, Alyssa Bouska, Francisco Vega, James R. Cook, Timothy C. Greiner, Andrew L. Feldman, Elaine S. Jaffe, Sarah L. Ondrejka, German Ott, Neval Ozkaya, Phil Raess, Andreas Rosenwald, Kerry J. Savage, Graham Slack, Joo Y. Song, Lisa M. Rimsza, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2023) 142 (Supplement 1): 1636.
https://doi.org/10.1182/blood-2023-186950
Published: 2023