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Journal Articles

Application of a Phenotype-Based Predictive Analytic in a Phase Ib Study of Selinexor and Venetoclax in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Somedeb Ball, Michael T. Byrne, Melissa A Fischer, Farrukh T. Awan, Ben K. Tomlinson, Tess Stopczynski, Lokesh Patil, Christine J. Gu, Chris Leonardi, Katherine J. Walsh, Gregory Dan Ayers, Ashwin Kishtagari, Kateryna Fedorov, Markus D. Lacher, Joseph Wagner, Sanjay R Mohan, Michael R. Savona

Blood (2024) 144 (Supplement 1): 6012.

https://doi.org/10.1182/blood-2024-209403

Published: 2024

Journal Articles

Prediction of Volasertib Sensitivity in Acute Myeloid Leukemia Relapsed or Refractory to Venetoclax Plus Azacitidine

Lokesh Patil, Christine J. Gu, Cristina Tognon, Nicola Long, Kara Johnson, Melissa A Fischer, Somedeb Ball, Michael R. Savona, Chris Leonardi, Joseph Wagner, Glenn Michelson, Markus D. Lacher

Blood (2024) 144 (Supplement 1): 5818.

https://doi.org/10.1182/blood-2024-206299

Published: 2024

Journal Articles

Preliminary Results from a Phase 1b Dose De-Escalation Stage of Abnl-Marro 001: An International MDS/MPN Working Group Study

Blood (2023) 142 (Supplement 1): 1874.

https://doi.org/10.1182/blood-2023-181673

Published: 2023

Journal Articles

DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data

Blood (2023) 142 (Supplement 1): 815.

https://doi.org/10.1182/blood-2023-187244

Published: 2023

Journal Articles

Hypomorphic RAG deficiency: impact of disease burden on survival and thymic recovery argues for early diagnosis and HSCT

Blood (2023) 141 (7): 713–724.

https://doi.org/10.1182/blood.2022017667

Published: 2023

Includes: Supplemental data

Journal Articles

Primary HSPC-Derived Monocytes with DNMT3A p.R882H Exhibit Activated Myeloid Cell Gene Signatures

Alexander J. Silver, Donovan J. Brown, Maria P. Arrate, Yu Wang, Melissa A. Fischer, Pawan Bhat, J. Brett Heimlich, Alexander G. Bick, P. Brent Ferrell, Yaomin Xu, Michael R. Savona

Blood (2022) 140 (Supplement 1): 2885–2886.

https://doi.org/10.1182/blood-2022-170803

Published: 2022

Journal Articles

Variable Response to BCL2 Inhibition in MDS Is Enhanced across MDS Subtypes with Synergistic Combination of BCL2+MCL1 Inhibition

Melissa A. Fischer, MSc, PhD, Maria Arrate, MSc, Merrida A Childress, PhD, Brianna N Smith, MD MS, Yuanbin Song, MD, Rana Gbyli, MS, Thomas Stricker, MD PhD, Stephanie Halene, MD, Michael R. Savona, MD

Blood (2019) 134 (Supplement_1): 2982.

https://doi.org/10.1182/blood-2019-126578

Published: 2019

Journal Articles

Oral Azacitidine and Cedazuridine Approximate Azacitidine Efficacy in a Murine Model

Haley E. Ramsey, PhDMSc, Maria Arrate, MSc, Londa Fuller, Agnieszka E. Gorska, MSc, Kelli Boyd, DVM, PhD, Melissa A. Fischer, MSc, PhD, Aram Oganesian, PhD, Mohammad Azab, MD, Michael R. Savona, MD

Blood (2019) 134 (Supplement_1): 1376.

https://doi.org/10.1182/blood-2019-125899

Published: 2019

Journal Articles

Combination of Selective Inhibitor of Nuclear Export (SINE) Compounds, Selinexor and KPT-8602, with Venetoclax (ABT-199) Displays Enhanced Activity in Leukemia and Large Cell Lymphoma

Melissa A. Fischer, PhD, Sharon Friedlander, PhD, Leah Hogdal, PhD, Pia Arrate, Hua Chang, PhD, Trinayan Kashyap, MS, Christian Argueta, PhD, Boris Klebanov, MA, MS, William Senapedis, PhD, Erkan Baloglu, PhD MBA, Margaret S. Lee, PhD, Sharon Shacham, PhD MBA, Michael R. Savona, MD

Blood (2016) 128 (22): 3949.

https://doi.org/10.1182/blood.V128.22.3949.3949

Published: 2016

Journal Articles

The Critical Requirement of the NKG2D Receptor On CD8+ T Cells in Killing Myeloma Cells.

Laleh X. Talebian, PhD, Dawn A Fischer, BS, Zbigniew M Szczepiorkowski, MD, PhD, FCAP, Charles L Sentman, MD, Kenneth R Meehan, MD

Blood (2009) 114 (22): 4733.

https://doi.org/10.1182/blood.V114.22.4733.4733

Published: 2009

Journal Articles

Langerhans Cell Histiocytosis with Hematological Dysfunction, Refractory to Standard Therapy Could Be Cured by an Association of 2-CdA and Ara-C: Concordant Results from the Observational Survey of Treated Patients and from a Nation Wide Registry.

Jean Donadieu, MD, PhD, C. Thomas, MD, V. Barlogis, MD, C. Galambrun, MD, A. Robert, MD, V. Gandemer, MD, Y. Bertrand, MD, M. Munzer, MD, J. Landman-Parker, MD, M. Ouache-Chardin, MD, Y. Perel, MD, P. Chastagner, MD, A. Fischer, MD, PhD, F. Bernard, MD, PhD

Blood (2007) 110 (11): 2412.

https://doi.org/10.1182/blood.V110.11.2412.2412

Published: 2007

Journal Articles

Study of the Correlation between Phenotype - Including Acute Leukemia/MDS- and Genotype in Shwachman Diamond Syndrome in 60 Patients from the French SCN Registry.

Blood (2007) 110 (11): 3301.

https://doi.org/10.1182/blood.V110.11.3301.3301

Published: 2007

Journal Articles

Adoptive Immunotherapy with Donor Allodepleted T Cells.

L. Dal Cortivo, N. Mahlaoui, C. Picard, B. Neven, I. Andre-Schmutz, J.M. Luby, C. Martinache, T. Paquet, F. Ledeist, A. Fischer, M. Cavazzana-Calvo

Blood (2005) 106 (11): 479.

https://doi.org/10.1182/blood.V106.11.479.479

Published: 2005

Journal Articles

Gene Therapy for Severe Combined Immunodeficiency X1.

Blood (2005) 106 (11): 195.

https://doi.org/10.1182/blood.V106.11.195.195

Published: 2005

Journal Articles

Cytogenetics in Pediatric MDS - Data of the EWOG-MDS 98 Study.

K. Michalova, H. B. Beverloo, G. Michaelsen, B. Schlegelberger, J. Harbott, O. A. Haas, G. B. Kerndrup, L. Sainati, E. Bergstraesser, H. Hasle, J. Starý, M. Trebo, M. M. Van den Heuvel-Eibrink, M. Zecca, P. Noellke, A. Fischer, C. M. Niemeyer, D. R. Betts

Blood (2005) 106 (11): 4914.

https://doi.org/10.1182/blood.V106.11.4914.4914

Published: 2005

Journal Articles

Histopathological Findings on Liver Biopsies (bx) Do Not Correlate with Serum Markers of Fibrosis and Necro-Inflammation in Hemophiliacs (HEM) Co-Infected with Hepatitis C (HCV) and Human Immunodeficiency Virus (HIV).

Sean A. Fischer, MD, Francis Carolyn, RNP, Kessler M. Craig, MD

Blood (2005) 106 (11): 3204.

https://doi.org/10.1182/blood.V106.11.3204.3204

Published: 2005

Journal Articles

γc Gene Transfer in the Presence of Stem Cell Factor, FLT-3L, Interleukin-7 (IL-7), IL-1, and IL-15 Cytokines Restores T-Cell Differentiation From γc(−) X-Linked Severe Combined Immunodeficiency Hematopoietic Progenitor Cells in Murine Fetal Thymic Organ Cultures

S. Hacein-Bey, G. De Saint Basile, J. Lemerle, A. Fischer, M. Cavazzana-Calvo

Blood (1998) 92 (11): 4090–4097.

https://doi.org/10.1182/blood.V92.11.4090

Published: 1998

Journal Articles

Role of interleukin-2 (IL-2), IL-7, and IL-15 in natural killer cell differentiation from cord blood hematopoietic progenitor cells and from gamma c transduced severe combined immunodeficiency X1 bone marrow cells

M Cavazzana-Calvo, S Hacein-Bey, G de Saint Basile, C De Coene, F Selz, F Le Deist, A Fischer

Blood (1996) 88 (10): 3901–3909.

https://doi.org/10.1182/blood.V88.10.3901.bloodjournal88103901

Published: 1996

Journal Articles

T-lymphocyte differentiation and proliferation in the absence of the cytoplasmic tail of the common cytokine receptor gamma c chain in a severe combined immune deficiency X1 patient

E Morelon, A Dautry-Varsat, F Le Deist, S Hacein-Bay, A Fischer, G de Saint Basile

Blood (1996) 88 (5): 1708–1717.

https://doi.org/10.1182/blood.V88.5.1708.1708

Published: 1996

Journal Articles

gamma-c gene transfer into SCID X1 patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function

H Hacein-Bey, M Cavazzana-Calvo, F Le Deist, A Dautry-Varsat, C Hivroz, I Riviere, O Danos, JM Heard, K Sugamura, A Fischer, G De Saint Basile

Blood (1996) 87 (8): 3108–3116.

https://doi.org/10.1182/blood.V87.8.3108.bloodjournal8783108

Published: 1996

NARROW

Application of a Phenotype-Based Predictive Analytic in a Phase Ib Study of Selinexor and Venetoclax in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Prediction of Volasertib Sensitivity in Acute Myeloid Leukemia Relapsed or Refractory to Venetoclax Plus Azacitidine

Preliminary Results from a Phase 1b Dose De-Escalation Stage of Abnl-Marro 001: An International MDS/MPN Working Group Study

DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data

Hypomorphic RAG deficiency: impact of disease burden on survival and thymic recovery argues for early diagnosis and HSCT

Primary HSPC-Derived Monocytes with DNMT3A p.R882H Exhibit Activated Myeloid Cell Gene Signatures

Variable Response to BCL2 Inhibition in MDS Is Enhanced across MDS Subtypes with Synergistic Combination of BCL2+MCL1 Inhibition

Oral Azacitidine and Cedazuridine Approximate Azacitidine Efficacy in a Murine Model

Combination of Selective Inhibitor of Nuclear Export (SINE) Compounds, Selinexor and KPT-8602, with Venetoclax (ABT-199) Displays Enhanced Activity in Leukemia and Large Cell Lymphoma

The Critical Requirement of the NKG2D Receptor On CD8+ T Cells in Killing Myeloma Cells.

Langerhans Cell Histiocytosis with Hematological Dysfunction, Refractory to Standard Therapy Could Be Cured by an Association of 2-CdA and Ara-C: Concordant Results from the Observational Survey of Treated Patients and from a Nation Wide Registry.

Study of the Correlation between Phenotype - Including Acute Leukemia/MDS- and Genotype in Shwachman Diamond Syndrome in 60 Patients from the French SCN Registry.

Adoptive Immunotherapy with Donor Allodepleted T Cells.

Gene Therapy for Severe Combined Immunodeficiency X1.

Cytogenetics in Pediatric MDS - Data of the EWOG-MDS 98 Study.

Histopathological Findings on Liver Biopsies (bx) Do Not Correlate with Serum Markers of Fibrosis and Necro-Inflammation in Hemophiliacs (HEM) Co-Infected with Hepatitis C (HCV) and Human Immunodeficiency Virus (HIV).

γc Gene Transfer in the Presence of Stem Cell Factor, FLT-3L, Interleukin-7 (IL-7), IL-1, and IL-15 Cytokines Restores T-Cell Differentiation From γc(−) X-Linked Severe Combined Immunodeficiency Hematopoietic Progenitor Cells in Murine Fetal Thymic Organ Cultures

Role of interleukin-2 (IL-2), IL-7, and IL-15 in natural killer cell differentiation from cord blood hematopoietic progenitor cells and from gamma c transduced severe combined immunodeficiency X1 bone marrow cells

T-lymphocyte differentiation and proliferation in the absence of the cytoplasmic tail of the common cytokine receptor gamma c chain in a severe combined immune deficiency X1 patient

gamma-c gene transfer into SCID X1 patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function

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American Society of Hematology

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American Society of Hematology

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