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Journal Articles

Single- and double-hit events in genes encoding immune targets before and after T cell–engaging antibody therapy in MM

Marietta S. Truger, Johannes Duell, Xiang Zhou, Larissa Heimeshoff, Anna Ruckdeschel, Mara John, Angela Riedel, Sebastian Hüper, Jessica Peter, Wencke Walter, Larissa Haertle, Manja Meggendorfer, Max S. Topp, Andreas Rosenwald, Matteo Claudio Da Via, Niccolo Bolli, Niels Weinhold, Hermann Einsele, Claudia Haferlach, K. Martin Kortüm, Leo Rasche
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3794–3798.
https://doi.org/10.1182/bloodadvances.2021004418
Published: 2021
Includes: Supplemental data
Journal Articles

Fatal late-onset CAR T-cell–mediated encephalitis after axicabtagene-ciloleucel in a patient with large B-cell lymphoma

Clinical Trials & Observations
Susanne Jung, Jochen Greiner, Stephanie von Harsdorf, Pavle Popovic, Roland Moll, Jens Schittenhelm, Kosmas Kandilaris, Volker Daniel, Alexander Kunz, Michael Schmitt, Peter Dreger
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3789–3793.
https://doi.org/10.1182/bloodadvances.2021004889
Published: 2021
Includes: Supplemental data
Journal Articles

The promise and perils of immunotherapy

Stefanie Lesch, Saar Gill
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3709–3725.
https://doi.org/10.1182/bloodadvances.2021004453
Published: 2021
Journal Articles

Targeting pediatric leukemia-propagating cells with anti-CD200 antibody therapy

Paraskevi Diamanti, Charlotte V. Cox, Benjamin C. Ede, Robert A. Uger, John P. Moppett, Allison Blair
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3694–3708.
https://doi.org/10.1182/bloodadvances.2020003534
Published: 2021
Includes: Supplemental data
Journal Articles

Modified EASIX predicts severe cytokine release syndrome and neurotoxicity after chimeric antigen receptor T cells

Clinical Trials & Observations
Martina Pennisi, Miriam Sanchez-Escamilla, Jessica R. Flynn, Roni Shouval, Ana Alarcon Tomas, Mari Lynn Silverberg, Connie Batlevi, Renier J. Brentjens, Parastoo B. Dahi, Sean M. Devlin, Claudia Diamonte, Sergio Giralt, Elizabeth F. Halton, Tania Jain, Molly Maloy, Elena Mead, Maria Lia Palomba, Josel Ruiz, Bianca Santomasso, Craig S. Sauter, Michael Scordo, Gunjan L. Shah, Jae H. Park, Lucrecia Yanez San Segundo, Miguel-Angel Perales
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3397–3406.
https://doi.org/10.1182/bloodadvances.2020003885
Published: 2021
Includes: Supplemental data
Journal Articles

Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted

Clinical Trials & Observations
Jeremy D. Rubinstein, Xiang Zhu, Thomas Leemhuis, Giang Pham, Lorraine Ray, Sana Emberesh, Sonata Jodele, Shawn Thomas, Jose A. Cancelas, Catherine M. Bollard, Patrick J. Hanley, Michael D. Keller, Olivia Grimley, Diana Clark, Teri Clark, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Stella M. Davies, Adam S. Nelson, Michael S. Grimley, Carolyn Lutzko
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3309–3321.
https://doi.org/10.1182/bloodadvances.2021004456
Published: 2021
Includes: Supplemental data
Journal Articles

Development of immunosuppressive myeloid cells to induce tolerance in solid organ and hematopoietic cell transplant recipients

Clinical Trials & Observations
Kent P. Jensen, David A. Hongo, XuHuai Ji, PingPing Zheng, Rahul D. Pawar, Thomas Hsin-Hsu Wu, Stephan Busque, John D. Scandling, Judith A. Shizuru, Robert Lowsky, Asha Shori, Suparna Dutt, Jeffrey Waters, Anirudh Saraswathula, Jeanette Baker, John S. Tamaresis, Philip Lavori, Robert Negrin, Holden Maecker, Edgar G. Engleman, Everett Meyer, Samuel Strober
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3290–3302.
https://doi.org/10.1182/bloodadvances.2020003669
Published: 2021
Includes: Supplemental data
Journal Articles

Concordance of peripheral blood and bone marrow measurable residual disease in adult acute lymphoblastic leukemia

Clinical Trials & Observations
Lori Muffly, Vandana Sundaram, Connie Chen, Ilana Yurkiewicz, Eric Kuo, Sarah Burnash, Jay Y. Spiegel, Sally Arai, Matthew J. Frank, Laura J. Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Surbhi Sidana, Parveen Shiraz, Judith A. Shizuru, Wen-Kai Weng, Michaela Liedtke, Hyma T. Vempaty, David B. Miklos
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3147–3151.
https://doi.org/10.1182/bloodadvances.2021004234
Published: 2021
Includes: Supplemental data
Journal Articles

Effective anti-BCMA retreatment in multiple myeloma

Clinical Trials & Observations
Nicolas Gazeau, David Beauvais, Ibrahim Yakoub-Agha, Suman Mitra, Timothy B. Campbell, Thierry Facon, Salomon Manier
Journal: Blood Advances
Blood Adv (2021) 5 (15): 3016–3020.
https://doi.org/10.1182/bloodadvances.2021004176
Published: 2021
Journal Articles

Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy

Peter G. Miller, Adam S. Sperling, Elliott J. Brea, Mark B. Leick, Geoffrey G. Fell, Max Jan, Satyen H. Gohil, Yu-Tzu Tai, Nikhil C. Munshi, Catherine J. Wu, Donna S. Neuberg, Marcela V. Maus, Caron Jacobson, Christopher J. Gibson, Benjamin L. Ebert
Journal: Blood Advances
Blood Adv (2021) 5 (15): 2982–2986.
https://doi.org/10.1182/bloodadvances.2021004554
Published: 2021
Includes: Supplemental data
Journal Articles

Genomic and clinical characterization of early T-cell precursor lymphoblastic lymphoma

Clinical Trials & Observations
Xinjie Xu, Christian N. Paxton, Robert J. Hayashi, Kimberly P. Dunsmore, Stuart S. Winter, Stephen P. Hunger, Naomi J. Winick, William L. Carroll, Mignon L. Loh, Meenakshi Devidas, Thomas G. Gross, Catherine M. Bollard, Sherrie L. Perkins, Rodney R. Miles
Journal: Blood Advances
Blood Adv (2021) 5 (14): 2890–2900.
https://doi.org/10.1182/bloodadvances.2021004334
Published: 2021
Includes: Supplemental data
Journal Articles

Intratumoral T cells have a differential impact on FDG-PET parameters in follicular lymphoma

Karthik Nath, Soi-Cheng Law, Muhammed B. Sabdia, Jay Gunawardana, Lilia M. de Long, David Sester, Mohamed Shanavas, Hennes Tsang, Joshua W. D. Tobin, Sarah-Jane Halliday, Annette Hernandez, Donna Cross, Robert J. Bird, Sanjiv Jain, Colm Keane, Dipti Talaulikar, Judith Trotman, Phillip Law, Maher K. Gandhi
Journal: Blood Advances
Blood Adv (2021) 5 (12): 2644–2649.
https://doi.org/10.1182/bloodadvances.2020004051
Published: 2021
Includes: Supplemental data
Journal Articles

Blueprint for the discovery of biomarkers of toxicity and efficacy for CAR T cells and T-cell engagers

Clinical Trials & Observations
Sophie Paczesny, Marcelo C. Pasquini, Steven Z. Pavletic, Amit Agarwal, Stephen Spellman, Leslie Kean, Chantale Bernatchez, Juliane Gust, Verena Staedtke, Miguel-Angel Perales
Journal: Blood Advances
Blood Adv (2021) 5 (11): 2519–2522.
https://doi.org/10.1182/bloodadvances.2021004604
Published: 2021
Includes: Supplemental data
Journal Articles

Effect of lisocabtagene maraleucel on HRQoL and symptom severity in relapsed/refractory large B-cell lymphoma

Clinical Trials & Observations
Donald L. Patrick, Annette Powers, Monika Parisi Jun, Yeonhee Kim, Jacob Garcia, Christine Dehner, David G. Maloney
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2245–2255.
https://doi.org/10.1182/bloodadvances.2020003503
Published: 2021
Includes: Supplemental data
Journal Articles

Preclinical activity and determinants of response of the GPRC5DxCD3 bispecific antibody talquetamab in multiple myeloma

Christie P. M. Verkleij, Marloes E. C. Broekmans, Mark van Duin, Kristine A. Frerichs, Rowan Kuiper, A. Vera de Jonge, Martin Kaiser, Gareth Morgan, Amy Axel, Rengasamy Boominathan, Jocelyn Sendecki, Amy Wong, Raluca I. Verona, Pieter Sonneveld, Sonja Zweegman, Homer C. Adams, III, Tuna Mutis, Niels W. C. J. van de Donk
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2196–2215.
https://doi.org/10.1182/bloodadvances.2020003805
Published: 2021
Includes: Supplemental data
Journal Articles

Activity of blinatumomab in lymphoblastic leukemia with impaired T-cell immunity due to congenital immunodeficiency

Clinical Trials & Observations
Sandheeah Ramdeny, Asima Chaudhary, Austen Worth, Sara Ghorashian, Mary Slatter, Su Han Lum, Ajay Vora
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2153–2155.
https://doi.org/10.1182/bloodadvances.2021004284
Published: 2021
Journal Articles

Absolute lymphocyte count proliferation kinetics after CAR T-cell infusion impact response and relapse

Clinical Trials & Observations
Sophia Faude, Jane Wei, Kavitha Muralidharan, Xiaoming Xu, Gerald Wertheim, Michele Paessler, Vijay G. Bhoj, Stephan A. Grupp, Shannon L. Maude, Susan R. Rheingold, Vinodh Pillai
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2128–2136.
https://doi.org/10.1182/bloodadvances.2020004038
Published: 2021
Includes: Supplemental data
Journal Articles

Lenalidomide triggers T-cell effector functions in vivo in patients with follicular lymphoma

Cédric Ménard, Delphine Rossille, Joelle Dulong, Tien-Tuan Nguyen, Ilenia Papa, Maelle Latour, Nadège Bescher, Isabelle Bezier, Myriam Chouteau, Thierry Fest, Roch Houot, Franck Morschhauser, Karin Tarte
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2063–2074.
https://doi.org/10.1182/bloodadvances.2020003774
Published: 2021
Includes: Supplemental data
Journal Articles

Functional characterization of PD1 + TIM3 + tumor-infiltrating T cells in DLBCL and effects of PD1 or TIM3 blockade

Mikaël Roussel, Kieu-Suong Le, Clémence Granier, Francisco Llamas Gutierrez, Etienne Foucher, Simon Le Gallou, Céline Pangault, Luc Xerri, Vincent Launay, Thierry Lamy, Eric Tartour, Daniel Olive, Thierry Fest
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1816–1829.
https://doi.org/10.1182/bloodadvances.2020003080
Published: 2021
Includes: Supplemental data
Journal Articles

Microenvironment immune reconstitution patterns correlate with outcomes after autologous transplant in multiple myeloma

Harsh Parmar, Morie Gertz, Emilie Ingrid Anderson, Shaji Kumar, Taxiarchis V. Kourelis
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1797–1804.
https://doi.org/10.1182/bloodadvances.2020003857
Published: 2021
Includes: Supplemental data