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Journal Articles

DKK1 activates noncanonical NF-κB signaling via IL-6–induced CKAP4 receptor in multiple myeloma

Xin Li, Jingjing Wang, Shuai Zhu, Jinxin Zheng, Ying Xie, Hongmei Jiang, Jing Guo, Yixuan Wang, Ziyi Peng, Mengqi Wang, Jingya Wang, Sheng Wang, Yuping Zhong, Zhiqiang Liu
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3656–3667.
https://doi.org/10.1182/bloodadvances.2021004315
Published: 2021
Includes: Supplemental data
Journal Articles

G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death

Eva De Smedt, Julie Devin, Catharina Muylaert, Nicolas Robert, Guilhem Requirand, Philip Vlummens, Laure Vincent, Guillaume Cartron, Ken Maes, Jerome Moreaux, Elke De Bruyne
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2325–2338.
https://doi.org/10.1182/bloodadvances.2020003217
Published: 2021
Includes: Supplemental data
Journal Articles

The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma

Brittany C. Lipchick, Adam Utley, Zhannan Han, Sudha Moparthy, Dong Hyun Yun, Anna Bianchi-Smiraglia, David W. Wolff, Emily Fink, Liang Liu, Cristina M. Furdui, Jingyun Lee, Kelvin P. Lee, Mikhail A. Nikiforov
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1933–1946.
https://doi.org/10.1182/bloodadvances.2020002578
Published: 2021
Includes: Supplemental data
Journal Articles

Clinical characteristics and treatment outcomes of newly diagnosed multiple myeloma with chromosome 1q abnormalities

Clinical Trials & Observations
Nadine Abdallah, Patricia Greipp, Prashant Kapoor, Morie A. Gertz, Angela Dispenzieri, Linda B. Baughn, Martha Q. Lacy, Suzanne R. Hayman, Francis K. Buadi, David Dingli, Ronald S. Go, Yi L. Hwa, Amie Fonder, Miriam Hobbs, Yi Lin, Nelson Leung, Taxiarchis Kourelis, Rahma Warsame, Mustaqeem Siddiqui, John Lust, Robert A. Kyle, Leif Bergsagel, Rhett Ketterling, S. Vincent Rajkumar, Shaji K. Kumar
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3509–3519.
https://doi.org/10.1182/bloodadvances.2020002218
Published: 2020
Includes: Supplemental data
Journal Articles

Metaphase cytogenetics and plasma cell proliferation index for risk stratification in newly diagnosed multiple myeloma

Patrick W. Mellors, Moritz Binder, Rhett P. Ketterling, Patricia T. Greipp, Linda B. Baughn, Jess F. Peterson, Dragan Jevremovic, Kathryn E. Pearce, Francis K. Buadi, Martha Q. Lacy, Morie A. Gertz, Angela Dispenzieri, Suzanne R. Hayman, Prashant Kapoor, Wilson I. Gonsalves, Yi L. Hwa, Amie Fonder, Miriam Hobbs, Taxiarchis Kourelis, Rahma Warsame, John A. Lust, Nelson Leung, Ronald S. Go, Robert A. Kyle, S. Vincent Rajkumar, Shaji K. Kumar
Journal: Blood Advances
Blood Adv (2020) 4 (10): 2236–2244.
https://doi.org/10.1182/bloodadvances.2019001275
Published: 2020
Includes: Supplemental data
Journal Articles

Chromosome 1 abnormalities and survival of patients with multiple myeloma in the era of novel agents

Clinical Trials & Observations
Smith Giri, Scott F. Huntington, Rong Wang, Amer M. Zeidan, Nikolai Podoltsev, Steven D. Gore, Xiaomei Ma, Cary P. Gross, Amy J. Davidoff, Natalia Neparidze
Journal: Blood Advances
Blood Adv (2020) 4 (10): 2245–2253.
https://doi.org/10.1182/bloodadvances.2019001425
Published: 2020
Journal Articles

Measurement of ex vivo resistance to proteasome inhibitors, IMiDs, and daratumumab during multiple myeloma progression

Clinical Trials & Observations
Zachary J. Walker, Michael J. VanWyngarden, Brett M. Stevens, Diana Abbott, Andrew Hammes, Christophe Langouët-Astrie, Clayton A. Smith, Brent E. Palmer, Peter A. Forsberg, Tomer M. Mark, Craig T. Jordan, Daniel W. Sherbenou
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1628–1639.
https://doi.org/10.1182/bloodadvances.2019000122
Published: 2020
Includes: Supplemental data
Journal Articles

Integrative analysis of the genomic and transcriptomic landscape of double-refractory multiple myeloma

Bachisio Ziccheddu, Giulia Biancon, Filippo Bagnoli, Chiara De Philippis, Francesco Maura, Even H. Rustad, Matteo Dugo, Andrea Devecchi, Loris De Cecco, Marialuisa Sensi, Carolina Terragna, Marina Martello, Tina Bagratuni, Efstathios Kastritis, Meletios A. Dimopoulos, Michele Cavo, Cristiana Carniti, Vittorio Montefusco, Paolo Corradini, Niccolo Bolli
Journal: Blood Advances
Blood Adv (2020) 4 (5): 830–844.
https://doi.org/10.1182/bloodadvances.2019000779
Published: 2020
Includes: Supplemental data
Journal Articles

The impact of response kinetics for multiple myeloma in the era of novel agents

Clinical Trials & Observations
Yuting Yan, Xuehan Mao, Jiahui Liu, Huishou Fan, Chenxing Du, Zengjun Li, Shuhua Yi, Yan Xu, Rui Lv, Wei Liu, Shuhui Deng, Weiwei Sui, Qi Wang, Dehui Zou, Jianxiang Wang, Tao Cheng, Fenghuang Zhan, Yu-Tzu Tai, Chenglu Yuan, Xin Du, Lugui Qiu, Kenneth C. Anderson, Gang An
Journal: Blood Advances
Blood Adv (2019) 3 (19): 2895–2904.
https://doi.org/10.1182/bloodadvances.2019000432
Published: 2019
Includes: Supplemental data
Journal Articles

The SMAC mimetic LCL-161 displays antitumor activity in preclinical models of rituximab-resistant B-cell lymphoma

Kyle Runckel, Matthew J. Barth, Cory Mavis, Juan J. Gu, Francisco J. Hernandez-Ilizaliturri
Journal: Blood Advances
Blood Adv (2018) 2 (23): 3516–3525.
https://doi.org/10.1182/bloodadvances.2018018168
Published: 2018
Includes: Supplemental data
Journal Articles

An inhibitor of proteasome β2 sites sensitizes myeloma cells to immunoproteasome inhibitors

Sondra Downey-Kopyscinski, Ellen W. Daily, Marc Gautier, Ananta Bhatt, Bogdan I. Florea, Constantine S. Mitsiades, Paul G. Richardson, Christoph Driessen, Herman S. Overkleeft, Alexei F. Kisselev
Journal: Blood Advances
Blood Adv (2018) 2 (19): 2443–2451.
https://doi.org/10.1182/bloodadvances.2018016360
Published: 2018
Includes: Supplemental data
Journal Articles

Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates

Jean Kwun, Christopher Burghuber, Miriam Manook, Brian Ezekian, Jaeberm Park, Janghoon Yoon, John S. Yi, Neal Iwakoshi, Adriana Gibby, Jung Joo Hong, Alton B. Farris, Allan D. Kirk, Stuart J. Knechtle
Journal: Blood Advances
Blood Adv (2017) 1 (24): 2115–2119.
https://doi.org/10.1182/bloodadvances.2017010991
Published: 2017
Includes: Supplemental data
Journal Articles

TG02 inhibits proteasome inhibitor–induced HSF1 serine 326 phosphorylation and heat shock response in multiple myeloma

Shardule P. Shah, Ajay K. Nooka, Sagar Lonial, Lawrence H. Boise
Journal: Blood Advances
Blood Adv (2017) 1 (21): 1848–1853.
https://doi.org/10.1182/bloodadvances.2017006122
Published: 2017
Includes: Supplemental data
Journal Articles

Network meta-analysis of randomized trials in multiple myeloma: efficacy and safety in relapsed/refractory patients

Cirino Botta, Domenico Ciliberto, Marco Rossi, Nicoletta Staropoli, Maria Cucè, Teresa Galeano, Pierosandro Tagliaferri, Pierfrancesco Tassone
Journal: Blood Advances
Blood Adv (2017) 1 (7): 455–466.
https://doi.org/10.1182/bloodadvances.2016003905
Published: 2017
Includes: Supplemental data
Journal Articles

Bortezomib-based antibody depletion for refractory autoimmune hematological diseases

Clinical Trials & Observations
Sumita Ratnasingam, Patricia A. Walker, Huy Tran, Zane S. Kaplan, James D. McFadyen, Huyen Tran, Tse-Chieh Teh, Shaun Fleming, John V. Catalano, Sanjeev D. Chunilal, Anna Johnston, Stephen S. Opat, Jake Shortt
Journal: Blood Advances
Blood Adv (2016) 1 (1): 31–35.
https://doi.org/10.1182/bloodadvances.2016001412
Published: 2016