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Journal Articles

Bortezomib and rituximab in de novo adolescent/adult CD20-positive, Ph-negative pre-B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Hasmukh Jain, Manju Sengar, Vasu Babu Goli, Jayashree Thorat, Prashant Tembhare, Dhanlaxmi Shetty, V. N. Avinash Bonda, Lingaraj Nayak, P. G. Subramanian, Bhausaheb Bagal, Nikhil Patkar, Neha Sharma, Himanshi Gupta, Sumeet Gujral
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3436–3444.
https://doi.org/10.1182/bloodadvances.2020003368
Published: 2021
Journal Articles

Modified EASIX predicts severe cytokine release syndrome and neurotoxicity after chimeric antigen receptor T cells

Clinical Trials & Observations
Martina Pennisi, Miriam Sanchez-Escamilla, Jessica R. Flynn, Roni Shouval, Ana Alarcon Tomas, Mari Lynn Silverberg, Connie Batlevi, Renier J. Brentjens, Parastoo B. Dahi, Sean M. Devlin, Claudia Diamonte, Sergio Giralt, Elizabeth F. Halton, Tania Jain, Molly Maloy, Elena Mead, Maria Lia Palomba, Josel Ruiz, Bianca Santomasso, Craig S. Sauter, Michael Scordo, Gunjan L. Shah, Jae H. Park, Lucrecia Yanez San Segundo, Miguel-Angel Perales
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3397–3406.
https://doi.org/10.1182/bloodadvances.2020003885
Published: 2021
Includes: Supplemental data
Journal Articles

IKZF1 alterations are not associated with outcome in 498 adults with B-precursor ALL enrolled in the UKALL14 trial

Rachel J. Mitchell, Amy A. Kirkwood, Emilio Barretta, Laura Clifton-Hadley, Emma Lawrie, SooWah Lee, Daniel Leongamornlert, David I. Marks, Andrew K. McMillan, Tobias F. Menne, Elli Papaemmanuil, Bela Patel, Pip Patrick, Clare J. Rowntree, Nahid Zareian, Krisztina Zuborne Alapi, Anthony V. Moorman, Adele K. Fielding
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3322–3332.
https://doi.org/10.1182/bloodadvances.2021004430
Published: 2021
Includes: Supplemental data
Journal Articles

B-cell acute lymphoblastic leukemia in patients with germline RUNX1 mutations

Clinical Trials & Observations
Kathryn A. Six, Ulrike Gerdemann, Anna L. Brown, Andrew E. Place, Alan B. Cantor, Matthew A. Kutny, Serine Avagyan
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3199–3202.
https://doi.org/10.1182/bloodadvances.2021004653
Published: 2021
Journal Articles

Absolute lymphocyte count proliferation kinetics after CAR T-cell infusion impact response and relapse

Clinical Trials & Observations
Sophia Faude, Jane Wei, Kavitha Muralidharan, Xiaoming Xu, Gerald Wertheim, Michele Paessler, Vijay G. Bhoj, Stephan A. Grupp, Shannon L. Maude, Susan R. Rheingold, Vinodh Pillai
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2128–2136.
https://doi.org/10.1182/bloodadvances.2020004038
Published: 2021
Includes: Supplemental data
Journal Articles

Caloric and nutrient restriction to augment chemotherapy efficacy for acute lymphoblastic leukemia: the IDEAL trial

Clinical Trials & Observations
Etan Orgel, Celia Framson, Rubi Buxton, Jiyoon Kim, Gang Li, Jonathan Tucci, David R. Freyer, Weili Sun, Matthew J. Oberley, Christina Dieli-Conwright, Steven D. Mittelman
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1853–1861.
https://doi.org/10.1182/bloodadvances.2020004018
Published: 2021
Includes: Supplemental data
Journal Articles

Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis

Florian Renosi, Anne Roggy, Ambre Giguelay, Lou Soret, Pierre-Julien Viailly, Meyling Cheok, Sabeha Biichle, Fanny Angelot-Delettre, Vahid Asnafi, Elizabeth Macintyre, Sandrine Geffroy, Mary Callanan, Tony Petrella, Eric Deconinck, Etienne Daguindau, Véronique Harrivel, Sabrina Bouyer, Véronique Salaun, Pascale Saussoy, Jean Feuillard, Pascal Fuseau, Philippe Saas, Olivier Adotévi, Fabrice Jardin, Christophe Ferrand, Claude Preudhomme, Jacques Colinge, Christophe Roumier, Francine Garnache-Ottou
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1540–1551.
https://doi.org/10.1182/bloodadvances.2020003359
Published: 2021
Includes: Supplemental data
Journal Articles

Outcomes and prognostic factors in adolescents and young adults with ALL treated with a modified BFM-90 protocol

Clinical Trials & Observations
Akhil Rajendra, Hasmukh Jain, V. N. Avinash Bonda, Lingaraj Nayak, Prashant Tembhare, Dhanlaxmi Shetty, Jayashree Thorat, Hemani Jain, Papagudi Ganesan Subramanian, Nikhil Patkar, Gaurav Chatterjee, Navin Khattry, Anant Gokarn, Sachin Punatar, Smruti Mokal, Bhausaheb Bagal, Manju Sengar
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1178–1193.
https://doi.org/10.1182/bloodadvances.2020003526
Published: 2021
Includes: Supplemental data
Journal Articles

CD81 knockout promotes chemosensitivity and disrupts in vivo homing and engraftment in acute lymphoblastic leukemia

Anthony Quagliano, Anilkumar Gopalakrishnapillai, E. Anders Kolb, Sonali P. Barwe
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4393–4405.
https://doi.org/10.1182/bloodadvances.2020001592
Published: 2020
Includes: Supplemental data
Journal Articles

Efficacy and safety of anti-CD19 CAR T-cell therapy in 110 patients with B-cell acute lymphoblastic leukemia with high-risk features

Clinical Trials & Observations
Xian Zhang, Xin-an Lu, Junfang Yang, Gailing Zhang, Jingjing Li, Lisong Song, Yunchao Su, Yanze Shi, Min Zhang, Jiujiang He, Dan Song, Fanyong Lv, Wenqian Li, Yan Wu, Hui Wang, Hongxing Liu, Xiaosu Zhou, Ting He, Peihua Lu
Journal: Blood Advances
Blood Adv (2020) 4 (10): 2325–2338.
https://doi.org/10.1182/bloodadvances.2020001466
Published: 2020
Includes: Supplemental data
Journal Articles

The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia

Lauren M. Brown, Andrew Lonsdale, Andrea Zhu, Nadia M. Davidson, Breon Schmidt, Anthony Hawkins, Elise Wallach, Michelle Martin, Francoise M. Mechinaud, Seong Lin Khaw, Ray C. Bartolo, Louise E. A. Ludlow, Jackie Challis, Ian Brooks, Vida Petrovic, Nicola C. Venn, Rosemary Sutton, Ian J. Majewski, Alicia Oshlack, Paul G. Ekert
Journal: Blood Advances
Blood Adv (2020) 4 (5): 930–942.
https://doi.org/10.1182/bloodadvances.2019001008
Published: 2020
Includes: Supplemental data
Journal Articles

Comparing CAR T-cell toxicity grading systems: application of the ASTCT grading system and implications for management

Clinical Trials & Observations
Martina Pennisi, Tania Jain, Bianca D. Santomasso, Elena Mead, Kitsada Wudhikarn, Mari Lynne Silverberg, Yakup Batlevi, Roni Shouval, Sean M. Devlin, Connie Batlevi, Renier J. Brentjens, Parastoo B. Dahi, Claudia Diamonte, Sergio Giralt, Elizabeth F. Halton, Molly Maloy, Maria Lia Palomba, Miriam Sanchez-Escamilla, Craig S. Sauter, Michael Scordo, Gunjan Shah, Jae H. Park, Miguel-Angel Perales
Journal: Blood Advances
Blood Adv (2020) 4 (4): 676–686.
https://doi.org/10.1182/bloodadvances.2019000952
Published: 2020
Journal Articles

Tisagenlecleucel cellular kinetics, dose, and immunogenicity in relation to clinical factors in relapsed/refractory DLBCL

Clinical Trials & Observations
Rakesh Awasthi, Lida Pacaud, Edward Waldron, Constantine S. Tam, Ulrich Jäger, Peter Borchmann, Samantha Jaglowski, Stephen Ronan Foley, Koen van Besien, Nina D. Wagner-Johnston, Marie José Kersten, Stephen J. Schuster, Gilles Salles, Richard T. Maziarz, Özlem Anak, Christopher del Corral, Jufen Chu, Irina Gershgorin, Iulian Pruteanu-Malinici, Abhijit Chakraborty, Karen Thudium Mueller, Edmund K. Waller
Journal: Blood Advances
Blood Adv (2020) 4 (3): 560–572.
https://doi.org/10.1182/bloodadvances.2019000525
Published: 2020
Includes: Supplemental data
Journal Articles

Loncastuximab tesirine, an anti-CD19 antibody-drug conjugate, in relapsed/refractory B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Nitin Jain, Wendy Stock, Amer Zeidan, Ehab Atallah, James McCloskey, Leonard Heffner, Benjamin Tomlinson, Bhavana Bhatnagar, Jay Feingold, David Ungar, Grace Chao, Xiaoyan Zhang, Yajuan Qin, Karin Havenith, Hagop Kantarjian, Matthew J. Wieduwilt
Journal: Blood Advances
Blood Adv (2020) 4 (3): 449–457.
https://doi.org/10.1182/bloodadvances.2019000767
Published: 2020
Includes: Supplemental data
Journal Articles

Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival

Oscar Brück, Olli Dufva, Helena Hohtari, Sami Blom, Riku Turkki, Mette Ilander, Panu Kovanen, Celine Pallaud, Pedro Marques Ramos, Hanna Lähteenmäki, Katja Välimäki, Mohamed El Missiry, Antonio Ribeiro, Olli Kallioniemi, Kimmo Porkka, Teijo Pellinen, Satu Mustjoki
Journal: Blood Advances
Blood Adv (2020) 4 (2): 274–286.
https://doi.org/10.1182/bloodadvances.2019000792
Published: 2020
Includes: Supplemental data
Journal Articles

Clinical diagnostics and treatment strategies for Philadelphia chromosome–like acute lymphoblastic leukemia

Clinical Trials & Observations
Richard C. Harvey, Sarah K. Tasian
Journal: Blood Advances
Blood Adv (2020) 4 (1): 218–228.
https://doi.org/10.1182/bloodadvances.2019000163
Published: 2020
Journal Articles

CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy

Vinodh Pillai, Kavitha Muralidharan, Wenzhao Meng, Asen Bagashev, Derek A. Oldridge, Jaclyn Rosenthal, John Van Arnam, Jos J. Melenhorst, Diwakar Mohan, Amanda M. DiNofia, Minjie Luo, Sindhu Cherian, Jonathan R. Fromm, Gerald Wertheim, Andrei Thomas-Tikhonenko, Michele Paessler, Carl H. June, Eline T. Luning Prak, Vijay G. Bhoj, Stephan A. Grupp, Shannon L. Maude, Susan R. Rheingold
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3539–3549.
https://doi.org/10.1182/bloodadvances.2019000692
Published: 2019
Includes: Supplemental data
Journal Articles

B-cell acute lymphoblastic leukemia with high mutation burden presenting in a child with constitutional mismatch repair deficiency

Clinical Trials & Observations
Benjamin Oshrine, Nanette Grana, Colin Moore, Johnny Nguyen, Melissa Crenshaw, Melissa Edwards, Sumedha Sudhaman, Victoria J. Forster, Uri Tabori
Journal: Blood Advances
Blood Adv (2019) 3 (12): 1795–1798.
https://doi.org/10.1182/bloodadvances.2019000358
Published: 2019
Journal Articles

Inotuzumab: from preclinical development to success in B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Joseph Wynne, David Wright, Wendy Stock
Journal: Blood Advances
Blood Adv (2019) 3 (1): 96–104.
https://doi.org/10.1182/bloodadvances.2018026211
Published: 2019
Journal Articles

Driver mutations in Janus kinases in a mouse model of B-cell leukemia induced by deletion of PU.1 and Spi-B

Carolina R. Batista, Michelle Lim, Anne-Sophie Laramée, Faisal Abu-Sardanah, Li S. Xu, Rajon Hossain, Gillian I. Bell, David A. Hess, Rodney P. DeKoter
Journal: Blood Advances
Blood Adv (2018) 2 (21): 2798–2810.
https://doi.org/10.1182/bloodadvances.2018019950
Published: 2018
Includes: Supplemental data