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Treating lymphoma is now a bit EZ-er
Activity of blinatumomab in lymphoblastic leukemia with impaired T-cell immunity due to congenital immunodeficiency
Caplacizumab prevents refractoriness and mortality in acquired thrombotic thrombocytopenic purpura: integrated analysis
IGVL gene region usage correlates with distinct clinical presentation in IgM vs non-IgM light chain amyloidosis
Efficacy and safety of prophylactic high-dose MTX in high-risk DLBCL: a treatment intent–based analysis
Prevalence, predictors, and outcomes of clonal hematopoiesis in individuals aged ≥80 years
Absolute lymphocyte count proliferation kinetics after CAR T-cell infusion impact response and relapse
Infection-related morbidity and mortality among older patients with DLBCL treated with full- or attenuated-dose R-CHOP
Single-center experience with venetoclax combinations in patients with newly diagnosed and relapsed AML evolving from MPNs
Impact of splicing mutations in acute myeloid leukemia treated with hypomethylating agents combined with venetoclax
Characteristics, complications, and sites of bleeding among infants and toddlers less than 2 years of age with VWD
Can palliative care consultation increase integration of palliative care for patients with hematologic malignancies?
Clinical, molecular, and prognostic comparisons between CCUS and lower-risk MDS: a study of 187 molecularly annotated patients
A novel differentiation response with combination IDH inhibitor and intensive induction therapy for AML
Issue Archive
April 27 2021
Table of Contents
DRUG ADVANCES
Treating lymphoma is now a bit EZ-er
Clinical Trials & Observations
EXCEPTIONAL CASE REPORT
Activity of blinatumomab in lymphoblastic leukemia with impaired T-cell immunity due to congenital immunodeficiency
Clinical Trials & Observations
STIMULUS REPORT
Caplacizumab prevents refractoriness and mortality in acquired thrombotic thrombocytopenic purpura: integrated analysis
Clinical Trials & Observations
Flora Peyvandi,Spero Cataland,Marie Scully,Paul Coppo,Paul Knoebl,Johanna A. Kremer Hovinga,Ara Metjian,Javier de la Rubia,Katerina Pavenski,Jessica Minkue Mi Edou,Hilde De Winter,Filip Callewaert
SYSTEMATIC REVIEWS
Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism
Parth Patel,Payal Patel,Meha Bhatt,Cody Braun,Housne Begum,Robby Nieuwlaat,Rasha Khatib,Carolina C. Martins,Yuan Zhang,Itziar Etxeandia-Ikobaltzeta,Jamie Varghese,Hani Alturkmani,Waled Bahaj,Mariam Baig,Rohan Kehar,Ahmad Mustafa,Rakesh Ponnapureddy,Anchal Sethi,Merrill Thomas,David Wooldridge,Wendy Lim,Shannon M. Bates,Eddy Lang,Grégoire Le Gal,Linda B. Haramati,Jeffrey Kline,Marc Righini,Wojtek Wiercioch,Holger Schünemann,Reem A. Mustafa
CLINICAL TRIALS AND OBSERVATIONS
IGVL gene region usage correlates with distinct clinical presentation in IgM vs non-IgM light chain amyloidosis
Clinical Trials & Observations
Surbhi Sidana,Surendra Dasari,Taxiarchis V. Kourelis,Angela Dispenzieri,David L. Murray,Rebecca L. King,Ellen D. McPhail,Marina Ramirez-Alvarado,Shaji K. Kumar,Morie A. Gertz
Efficacy and safety of prophylactic high-dose MTX in high-risk DLBCL: a treatment intent–based analysis
Clinical Trials & Observations
Hyehyun Jeong,Hyungwoo Cho,Hyeyeong Kim,Heejung Chae,Jung-Bok Lee,Kyoungmin Lee,Shin Kim,Sang-wook Lee,Jin-Sook Ryu,Kyung Won Kim,Eun Jin Chae,Jooryung Huh,Chan-Sik Park,Dok Hyun Yoon,Cheolwon Suh
HEMATOPOIESIS AND STEM CELLS
Prevalence, predictors, and outcomes of clonal hematopoiesis in individuals aged ≥80 years
Clinical Trials & Observations
Isabelle A. van Zeventer,Jonas B. Salzbrunn,Aniek O. de Graaf,Bert A. van der Reijden,H. Marike Boezen,Judith M. Vonk,Pim van der Harst,Jan Jacob Schuringa,Joop H. Jansen,Gerwin Huls
IMMUNOBIOLOGY AND IMMUNOTHERAPY
Absolute lymphocyte count proliferation kinetics after CAR T-cell infusion impact response and relapse
Clinical Trials & Observations
Sophia Faude,Jane Wei,Kavitha Muralidharan,Xiaoming Xu,Gerald Wertheim,Michele Paessler,Vijay G. Bhoj,Stephan A. Grupp,Shannon L. Maude,Susan R. Rheingold,Vinodh Pillai
LYMPHOID NEOPLASIA
Preclinical activity and determinants of response of the GPRC5DxCD3 bispecific antibody talquetamab in multiple myeloma
Christie P. M. Verkleij,Marloes E. C. Broekmans,Mark van Duin,Kristine A. Frerichs,Rowan Kuiper,A. Vera de Jonge,Martin Kaiser,Gareth Morgan,Amy Axel,Rengasamy Boominathan,Jocelyn Sendecki,Amy Wong,Raluca I. Verona,Pieter Sonneveld,Sonja Zweegman,Homer C. Adams, III,Tuna Mutis,Niels W. C. J. van de Donk
Infection-related morbidity and mortality among older patients with DLBCL treated with full- or attenuated-dose R-CHOP
Clinical Trials & Observations
Toby A. Eyre,William Wilson,Amy A. Kirkwood,Julia Wolf,Catherine Hildyard,Hannah Plaschkes,John Griffith,Paul Fields,Arief Gunawan,Rebecca Oliver,Stephen Booth,Jaimal Kothari,Christopher P. Fox,Nicolas Martinez-Calle,Andrew McMillan,Mark Bishton,Graham P. Collins,Chris S. R. Hatton
MYELOID NEOPLASIA
Single-center experience with venetoclax combinations in patients with newly diagnosed and relapsed AML evolving from MPNs
Clinical Trials & Observations
Lucia Masarova,Courtney D. DiNardo,Prithviraj Bose,Naveen Pemmaraju,Naval G. Daver,Tapan M. Kadia,Helen T. Chifotides,Lingsha Zhou,Gautam Borthakur,Zeev Estrov,Marina Konopleva,Srdan Verstovsek
Impact of splicing mutations in acute myeloid leukemia treated with hypomethylating agents combined with venetoclax
Clinical Trials & Observations
Curtis A. Lachowiez,Sanam Loghavi,Ken Furudate,Guillermo Montalban-Bravo,Abhishek Maiti,Tapan Kadia,Naval Daver,Gautam Borthakur,Naveen Pemmaraju,Koji Sasaki,Yesid Alvarado,Musa Yilmaz,Nicholas J. Short,Kelly Chien,Maro Ohanian,Sherry Pierce,Keyur P. Patel,Elias Jabbour,Farhad Ravandi,Hagop M. Kantarjian,Guillermo Garcia-Manero,Koichi Takahashi,Marina Y. Konopleva,Courtney D. DiNardo
Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes
Grace A. Ward,Kathy L. McGraw,Farnoosh Abbas-Aghababazadeh,Benjamin S. Meyer,Amy F. McLemore,Nicole D. Vincelette,Nghi B. Lam,Amy L. Aldrich,Najla H. Al Ali,Eric Padron,Javier Pinilla-Ibarz,Erico Masala,Valeria Santini,Olivier Kosmider,Michaela Fontenay,Pierre Fenaux,Joseph Johnson,Brooke L. Fridley,Alan F. List
THROMBOSIS AND HEMOSTASIS
Characteristics, complications, and sites of bleeding among infants and toddlers less than 2 years of age with VWD
Clinical Trials & Observations
Brandi Dupervil,for the US Hemophilia Treatment Center Network,Karon Abe,for the US Hemophilia Treatment Center Network,Sarah H. O’Brien,for the US Hemophilia Treatment Center Network,Meredith Oakley,for the US Hemophilia Treatment Center Network,Roshni Kulkarni,for the US Hemophilia Treatment Center Network,Courtney D. Thornburg,for the US Hemophilia Treatment Center Network,Vanessa R. Byams,for the US Hemophilia Treatment Center Network,J. Michael Soucie,for the US Hemophilia Treatment Center Network
TRANSPLANTATION
RESEARCH LETTERS
Can palliative care consultation increase integration of palliative care for patients with hematologic malignancies?
Clinical Trials & Observations
Chloé Prod’homme,Licia Touzet,Magali Pierrat,Luc Chevalier,Helene Lesaffre,Celine Berthon,Valerie Coiteux,Sarah Barbieux,David Beauvais,Loïc Bauschert,Marie De Charette,Laure Goursaud,Salomon Manier,Thierry Facon
Clinical, molecular, and prognostic comparisons between CCUS and lower-risk MDS: a study of 187 molecularly annotated patients
Clinical Trials & Observations
Marissa Li,Moritz Binder,Terra Lasho,Alejandro Ferrer,Naseema Gangat,Aref Al-Kali,Abhishek Mangaonkar,Michelle Elliott,Mark Litzow,William Hogan,Animesh Pardanani,Alexandra Wolanskyj-Spinner,Matthew Howard,Rebecca L. King,Mithun Shah,Hassan Alkhateeb,Kebede Begna,Ayalew Tefferi,Christy Finke,Jennifer Oliveira,Rhett Ketterling,Horatiu Olteanu,Mrinal M. Patnaik
A novel differentiation response with combination IDH inhibitor and intensive induction therapy for AML
Clinical Trials & Observations
Emily F. Mason,Olga Pozdnyakova,Mikhail Roshal,Amir T. Fathi,Eytan M. Stein,P. Brent Ferrell,Aaron C. Shaver,Mark Frattini,Hongfang Wang,Lei Hua,Jimmy Mu,Sung Choe,Rengyi Xu,Caroline Almon,Michael Cooper,Richard M. Stone,Robert P. Hasserjian,Michael R. Savona
COMMENTARY
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Cover Image
Cover Image
COVER FIGURE
Eosinophil and red blood cells on peripheral blood smear. Photo 157623170 © CreativeEndeavors | Dreamstime.com - PDF Icon PDF LinkFront Matter
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