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Issue Archive

Volume 4, Issue 11
June 9 2020
Issue Cover

Table of Contents

BLOOD ADVANCES TALK

The great platelet paradox: evolution of platelet contribution to hemostasis, inflammation, and thrombosis after injury
Matthew D. Neal
View Articletitled, The great platelet paradox: evolution of platelet contribution to hemostasis, inflammation, and thrombosis after injury
Supplemental data

EXCEPTIONAL CASE REPORT

Interleukin-15 superagonist (N-803) treatment of PML and JCV in a post–allogeneic hematopoietic stem cell transplant patient
Clinical Trials & Observations
Aabha Oza,Michael P. Rettig,Phil Powell,Kathryn O’Brien,David B. Clifford,Julie Ritchey,Leah Gehrs,Julia Hollaway,Eugene Major,Todd A. Fehniger,Christopher A. Miller,Patrick Soon-Shiong,Amy Rock,John F. DiPersio
View Articletitled, Interleukin-15 superagonist (N-803) treatment of PML and JCV in a post–allogeneic hematopoietic stem cell transplant patient

STIMULUS REPORT

Apolipoprotein A-I enhances activated protein C cytoprotective activity
Eimear M. Gleeson,Aisling M. Rehill,Orla Willis Fox,Fionnuala Ni Ainle,Cormac J. McDonnell,Hannah J. Rushe,Seán McCluskey,James S. O’Donnell,Roger J. S. Preston
View Articletitled, Apolipoprotein A-I enhances activated protein C cytoprotective activity
Supplemental data

SYSTEMATIC REVIEW

Diagnosis of deep vein thrombosis of the upper extremity: a systematic review and meta-analysis of test accuracy
Payal Patel,Cody Braun,Parth Patel,Meha Bhatt,Housne Begum,Wojtek Wiercioch,Jamie Varghese,David Wooldridge,Hani J. Alturkmani,Merrill Thomas,Mariam Baig,Waled Bahaj,Rasha Khatib,Rohan Kehar,Rakesh Ponnapureddy,Anchal Sethi,Ahmad Mustafa,Wendy Lim,Grégoire Le Gal,Shannon M. Bates,Eddy Lang,Marc Righini,Nedaa M. Husainat,Mohamad A. Kalot,Yazan Nayif Al Jabiri,Robby Nieuwlaat,Holger J. Schünemann,Reem A. Mustafa
View Articletitled, Diagnosis of deep vein thrombosis of the upper extremity: a systematic review and meta-analysis of test accuracy
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Young adult outcomes of childhood prophylaxis for severe hemophilia A: results of the Joint Outcome Continuation Study
Clinical Trials & Observations
Beth Boulden Warren,Dianne Thornhill,Jill Stein,Michael Fadell,J. David Ingram,Sharon Funk,Kristi L. Norton,Heidi D. Lane,Carolyn M. Bennett,Amy Dunn,Michael Recht,Amy Shapiro,Marilyn J. Manco-Johnson
View Articletitled, Young adult outcomes of childhood prophylaxis for severe hemophilia A: results of the Joint Outcome Continuation Study
Supplemental data

HEMATOPOIESIS AND STEM CELLS

High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential
Lambert Busque,Maxine Sun,Manuel Buscarlet,Sami Ayachi,Yassamin Feroz Zada,Sylvie Provost,Vincent Bourgoin,Luigina Mollica,Marlies Meisel,Reinhard Hinterleitner,Bana Jabri,Marie-Pierre Dubé,Jean-Claude Tardif
View Articletitled, High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential
Supplemental data

LYMPHOID NEOPLASIA

Multiple mutations at exon 2 of RHOA detected in plasma from patients with peripheral T-cell lymphoma
Barbara Ottolini,Nadia Nawaz,Christopher S. Trethewey,Sami Mamand,Rebecca L. Allchin,Richard Dillon,Paul A. Fields,Matthew J. Ahearne,Simon D. Wagner
View Articletitled, Multiple mutations at exon 2 of RHOA detected in plasma from patients with peripheral T-cell lymphoma
Supplemental data
Novel mouse model resistant to irreversible BTK inhibitors: a tool identifying new therapeutic targets and side effects
H. Yesid Estupiñán,Thibault Bouderlique,Chenfei He,Anna Berglöf,Dhanu Gupta,Osama Saher,Miguel Ángel Daza Cruz,Lucia Peña-Perez,Liang Yu,Rula Zain,Mikael C. I. Karlsson,Robert Månsson,C. I. Edvard Smith
View Articletitled, Novel mouse model resistant to irreversible BTK inhibitors: a tool identifying new therapeutic targets and side effects
Supplemental data
Branched evolution and genomic intratumor heterogeneity in the pathogenesis of cutaneous T-cell lymphoma
Aishwarya Iyer,Dylan Hennessey,Sandra O’Keefe,Jordan Patterson,Weiwei Wang,Gane Ka-Shu Wong,Robert Gniadecki
View Articletitled, Branched evolution and genomic intratumor heterogeneity in the pathogenesis of cutaneous T-cell lymphoma
Supplemental data
Gene expression profiling of gray zone lymphoma
Clémentine Sarkozy,Lauren Chong,Katsuyoshi Takata,Elizabeth A. Chavez,Tomoko Miyata-Takata,Gerben Duns,Adèle Telenius,Merrill Boyle,Graham W. Slack,Camille Laurent,Pedro Farinha,Thierry J. Molina,Christiane Copie-Bergman,Diane Damotte,Gilles A. Salles,Anja Mottok,Kerry J. Savage,David W. Scott,Alexandra Traverse-Glehen,Christian Steidl
View Articletitled, Gene expression profiling of gray zone lymphoma
Supplemental data
ABVD followed by BV consolidation in risk-stratified patients with limited-stage Hodgkin lymphoma
Clinical Trials & Observations
Steven I. Park,Thomas C. Shea,Oludamilola Olajide,Nishitha M. Reddy,Lihua E. Budde,Nilanjan Ghosh,Allison M. Deal,Jeanne F. Noe,Stephen M. Ansell
View Articletitled, ABVD followed by BV consolidation in risk-stratified patients with limited-stage Hodgkin lymphoma
Supplemental data

MYELOID NEOPLASIA

Enhanced engraftment of human myelofibrosis stem and progenitor cells in MISTRG mice
Veronika Lysenko,Nicole Wildner-Verhey van Wijk,Kathrin Zimmermann,Marie-Christine Weller,Marco Bühler,Mattheus H. E. Wildschut,Patrick Schürch,Christine Fritz,Ulrich Wagner,Laura Calabresi,Bethan Psaila,Richard A. Flavell,Alessandro M. Vannucchi,Adam J. Mead,Peter J. Wild,Stefan Dirnhofer,Markus G. Manz,Alexandre P. A. Theocharides
View Articletitled, Enhanced engraftment of human myelofibrosis stem and progenitor cells in MISTRG mice
Supplemental data

THROMBOSIS AND HEMOSTASIS

Outcomes associated with apixaban vs warfarin in patients with renal dysfunction
Clinical Trials & Observations
Claudia Hanni,Elizabeth Petrovitch,Mona Ali,Whitney Gibson,Christopher Giuliano,Jenna Holzhausen,Charles Makowski,Amy Pallisco,Nisha Patel,Denise Sutter,Long To,Raymond Yost
View Articletitled, Outcomes associated with apixaban vs warfarin in patients with renal dysfunction
Comparing low-molecular-weight heparin dosing for treatment of venous thromboembolism in patients with obesity (RIETE registry)
Clinical Trials & Observations
Reza Mirza,Robby Nieuwlaat,Juan J. López-Núñez,Raquel Barba,Arnav Agarwal,Carme Font,Maurizio Ciammaichella,Elvira Grandone,Rick Ikesaka,Mark Crowther,Manuel Monreal,the RIETE Investigators
View Articletitled, Comparing low-molecular-weight heparin dosing for treatment of venous thromboembolism in patients with obesity (RIETE registry)
Supplemental data
Safety and feasibility of rivaroxaban in deferred workup of patients with suspected deep vein thrombosis
Clinical Trials & Observations
Synne G. Fronas,Anders E. A. Dahm,Hilde S. Wik,Camilla T. Jørgensen,Jostein Gleditsch,Nezar Raouf,René Holst,Frederikus A. Klok,Waleed Ghanima
View Articletitled, Safety and feasibility of rivaroxaban in deferred workup of patients with suspected deep vein thrombosis

TRANSPLANTATION

Dickkopf-related protein 3 is a novel biomarker for chronic GVHD after allogeneic hematopoietic cell transplantation
Yoshihiro Inamoto,Paul J. Martin,Stephanie J. Lee,Amin A. Momin,Laura Tabellini,Lynn E. Onstad,Joseph Pidala,Mary E. D. Flowers,Richard L. Lawler,Hiroyuki Katayama,Samir Hanash,John A. Hansen
View Articletitled, Dickkopf-related protein 3 is a novel biomarker for chronic GVHD after allogeneic hematopoietic cell transplantation
Supplemental data
New insights into risk factors for transplant-associated thrombotic microangiopathy in pediatric HSCT
Clinical Trials & Observations
Reem Elfeky,Giovanna Lucchini,Su-Han Lum,Giorgio Ottaviano,Natalia Builes,Zohreh Nademi,Alexandra Battersby,Terence Flood,Stephen Owens,Andrew J. Cant,Helen Young,Sinéad Greener,Patrick Walsh,David Kavanagh,Srinivas Annavarapu,Kanchan Rao,Persis Amrolia,Robert Chiesa,Austen Worth,Claire Booth,Roderick Skinner,Bilyana Doncheva,Joseph Standing,Andrew R. Gennery,Waseem Qasim,Mary Slatter,Paul Veys
View Articletitled, New insights into risk factors for transplant-associated thrombotic microangiopathy in pediatric HSCT
Supplemental data
Transient antibody targeting of CD45RC inhibits the development of graft-versus-host disease
Laetitia Boucault,Maria-Dolores Lopez Robles,Allan Thiolat,Séverine Bézie,Michael Schmueck-Henneresse,Cécile Braudeau,Nadège Vimond,Antoine Freuchet,Elodie Autrusseau,Frédéric Charlotte,Rabah Redjoul,Florence Beckerich,Mathieu Leclerc,Eliane Piaggio,Regis Josien,Hans-Dieter Volk,Sébastien Maury,José L. Cohen,Ignacio Anegon,Carole Guillonneau
View Articletitled, Transient antibody targeting of CD45RC inhibits the development of graft-versus-host disease
Supplemental data
Risk factors for transplant-associated thrombotic microangiopathy and mortality in a pediatric cohort
Clinical Trials & Observations
Michelle Schoettler,Leslie E. Lehmann,Steven Margossian,Maia Lee,Leslie S. Kean,Pei-Chi Kao,Clement Ma,Christine N. Duncan
View Articletitled, Risk factors for transplant-associated thrombotic microangiopathy and mortality in a pediatric cohort
Supplemental data

VASCULAR BIOLOGY

Mn porphyrins as a novel treatment targeting sickle cell NOXs to reverse and prevent acute vaso-occlusion in vivo
Madhan Thamilarasan,Rodolfo Estupinan,Ines Batinic-Haberle,Rahima Zennadi
View Articletitled, Mn porphyrins as a novel treatment targeting sickle cell NOXs to reverse and prevent acute vaso-occlusion in vivo
Supplemental data
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Risk factors for clonal hematopoiesis of indeterminate potential (CHIP). CHIP is age dependent. Several factors may influence its development. These include genetic predisposition, genotoxic exposure, and immune attack. This study further confirms the potential role of an inflammatory state in CHIP development. See the article by Busque et al.

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