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Markus G. Manz
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Journal Articles

Advantages of a genomic DNA-based NGS assay for detection of mutant NPM1 measurable residual disease in AML

Christian M Vonk, Tim Grob, Melissa Rijken, François G. Kavelaars, Jolinda Konijnenburg, Gert J Ossenkoppele, Markus G. Manz, Yngvar Floisand, Bob Löwenberg, Peter J.M. Valk
Journal: Blood Advances
Blood Adv bloodadvances.2024014490.
https://doi.org/10.1182/bloodadvances.2024014490
Published: 2024
Includes: Supplemental data
Journal Articles

Intrapatient competition of VEXAS syndrome and CML clones

Nadia Djerbi, Kathrin Zimmermann, Marco Roncador, Mike Oliver Becker, Markus G. Manz, Stefan Balabanov
Journal: Blood Advances
Blood Adv (2023) 7 (22): 6815–6818.
https://doi.org/10.1182/bloodadvances.2023010814
Published: 2023
Journal Articles

Addition of romiplostim to conditioning prior to HSCT allows chemotherapy reduction while maintaining engraftment levels

C. Matthias Wilk, Larisa V. Kovtonyuk, Markus G. Manz
Journal: Blood Advances
Blood Adv (2022) 6 (15): 4485–4489.
https://doi.org/10.1182/bloodadvances.2022007566
Published: 2022
Includes: Supplemental data
Journal Articles

Proteomic identification of proliferation and progression markers in human polycythemia vera stem and progenitor cells

Ge Tan, Witold E. Wolski, Sandra Kummer, Mara Hofstetter, Alexandre P. A. Theocharides, Markus G. Manz, Ruedi Aebersold, Fabienne Meier-Abt
Journal: Blood Advances
Blood Adv (2022) 6 (11): 3480–3493.
https://doi.org/10.1182/bloodadvances.2021005344
Published: 2022
Includes: Supplemental data
Journal Articles

TP53 mutations confer resistance to hypomethylating agents and BCL-2 inhibition in myeloid neoplasms

Roman R. Schimmer, Larisa V. Kovtonyuk, Nancy Klemm, Jonas Fullin, Sebastian M. Stolz, Jan Mueller, Francisco Caiado, Kari J. Kurppa, Benjamin L. Ebert, Markus G. Manz, Steffen Boettcher
Journal: Blood Advances
Blood Adv (2022) 6 (11): 3201–3206.
https://doi.org/10.1182/bloodadvances.2021005859
Published: 2022
Includes: Supplemental data
Journal Articles

CXCL12-abundant reticular cells are the major source of IL-6 upon LPS stimulation and thereby regulate hematopoiesis

Rahel C. Gerosa, Steffen Boettcher, Larisa V. Kovtonyuk, Annika Hausmann, Wolf-Dietrich Hardt, Juan Hidalgo, César Nombela-Arrieta, Markus G. Manz
Journal: Blood Advances
Blood Adv (2021) 5 (23): 5002–5015.
https://doi.org/10.1182/bloodadvances.2021005531
Published: 2021
Includes: Supplemental data
Journal Articles

Disruption of CSF-1R signaling inhibits growth of AML with inv(16)

Alexander Simonis, Norman F. Russkamp, Jan Mueller, C. Matthias Wilk, Mattheus H. E. Wildschut, Renier Myburgh, Nicole Wildner-Verhey van Wijk, Rouven Mueller, Stefan Balabanov, Peter J. M. Valk, Alexandre P. A. Theocharides, Markus G. Manz
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1273–1277.
https://doi.org/10.1182/bloodadvances.2020003125
Published: 2021
Includes: Supplemental data
Journal Articles

Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML: the HOVON-SAKK-132 trial

Clinical Trials & Observations
Bob Löwenberg, Thomas Pabst, Johan Maertens, Patrycja Gradowska, Bart J. Biemond, Olivier Spertini, Edo Vellenga, Laimonas Griskevicius, Lidwine W. Tick, Mojca Jongen-Lavrencic, Marinus van Marwijk Kooy, Marie-Christiane Vekemans, Walter J. F. M. van der Velden, Berna Beverloo, Lucienne Michaux, Carlos Graux, Dries Deeren, Okke de Weerdt, Joost W. J. van Esser, Mario Bargetzi, Saskia K. Klein, Alain Gadisseur, Peter E. Westerweel, Hendrik Veelken, Michael Gregor, Tobias Silzle, Daniëlle van Lammeren-Venema, Ine Moors, Dimitri A. Breems, Mels Hoogendoorn, Marie-Cecile J. C. Legdeur, Thomas Fischer, Juergen Kuball, Jan Cornelissen, Kimmo Porkka, Gunnar Juliusson, Peter Meyer, Martin Höglund, Bjorn T. Gjertsen, Jeroen J. W. M. Janssen, Gerwin Huls, Jakob Passweg, Jacqueline Cloos, Peter J. M. Valk, Catharina H. M. J. van Elssen, Markus G. Manz, Yngvar Floisand, Gert J. Ossenkoppele
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1110–1121.
https://doi.org/10.1182/bloodadvances.2020003855
Published: 2021
Includes: Supplemental data
Journal Articles

BRAF V 600E or mutant MAP2K1 human CD34 + cells establish Langerhans cell–like histiocytosis in immune-deficient mice

Anahita Rafiei, C. Matthias Wilk, Patrick M. Helbling, Renier Myburgh, Yasuyuki Saito, Eugenia Haralambieva, Davide Soldini, Rikhia Chakraborty, Miriam Merad, Carl E. Allen, Cesar Nombela-Arrieta, Markus G. Manz
Journal: Blood Advances
Blood Adv (2020) 4 (19): 4912–4917.
https://doi.org/10.1182/bloodadvances.2020001926
Published: 2020
Includes: Supplemental data
Journal Articles

Ibrutinib added to 10-day decitabine for older patients with AML and higher risk MDS

Clinical Trials & Observations
Gerwin Huls, Dana A. Chitu, Thomas Pabst, Saskia K. Klein, Georg Stussi, Laimonas Griskevicius, Peter J. M. Valk, Jacqueline Cloos, Arjan A. van de Loosdrecht, Dimitri Breems, Danielle van Lammeren-Venema, Isabelle van Zeventer, Rinske Boersma, Mojca Jongen-Lavrencic, Martin Fehr, Mels Hoogendoorn, Markus G. Manz, Maaike Söhne, Rien van Marwijk Kooy, Dries Deeren, Marjolein W. M. van der Poel, Marie Cecile Legdeur, Lidwine Tick, Yves Chalandon, Emanuele Ammatuna, Sabine Blum, Bob Löwenberg, Gert J. Ossenkoppele
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4267–4277.
https://doi.org/10.1182/bloodadvances.2020002846
Published: 2020
Includes: Supplemental data
Journal Articles

Enhanced engraftment of human myelofibrosis stem and progenitor cells in MISTRG mice

Veronika Lysenko, Nicole Wildner-Verhey van Wijk, Kathrin Zimmermann, Marie-Christine Weller, Marco Bühler, Mattheus H. E. Wildschut, Patrick Schürch, Christine Fritz, Ulrich Wagner, Laura Calabresi, Bethan Psaila, Richard A. Flavell, Alessandro M. Vannucchi, Adam J. Mead, Peter J. Wild, Stefan Dirnhofer, Markus G. Manz, Alexandre P. A. Theocharides
Journal: Blood Advances
Blood Adv (2020) 4 (11): 2477–2488.
https://doi.org/10.1182/bloodadvances.2019001364
Published: 2020
Includes: Supplemental data
Journal Articles

Pharmacological DNA demethylation restores SMAD1 expression and tumor suppressive signaling in diffuse large B-cell lymphoma

Anna Stelling, Cheuk-Ting Wu, Katrin Bertram, Hind Hashwah, Alexandre P. A. Theocharides, Markus G. Manz, Alexandar Tzankov, Anne Müller
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3020–3032.
https://doi.org/10.1182/bloodadvances.2019000210
Published: 2019
Includes: Supplemental data
Journal Articles

Quantification and three-dimensional microanatomical organization of the bone marrow

Cesar Nombela-Arrieta, Markus G. Manz
Journal: Blood Advances
Blood Adv (2017) 1 (6): 407–416.
https://doi.org/10.1182/bloodadvances.2016003194
Published: 2017