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Stefan Dirnhofer
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Journal Articles

The glutaminase inhibitor CB-839 targets metabolic dependencies of JAK2 -mutant hematopoiesis in MPN

Marc Usart, Nils Hansen, Jan Stetka, Tiago Almeida Fonseca, Alexandre Guy, Quentin Kimmerlin, Shivam Rai, Hui Hao-Shen, Julien Roux, Stefan Dirnhofer, Radek C. Skoda
Journal: Blood Advances
Blood Adv (2024) 8 (9): 2312–2325.
https://doi.org/10.1182/bloodadvances.2023010950
Published: 2024
Includes: Supplemental data
Journal Articles

IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2 -mutant hematopoietic stem cells

Shivam Rai, Yang Zhang, Elodie Grockowiak, Quentin Kimmerlin, Nils Hansen, Cedric B. Stoll, Marc Usart, Damien Luque Paz, Hui Hao-Shen, Yexuan Zhu, Julien Roux, Michael S. Bader, Stefan Dirnhofer, Christopher J. Farady, Timm Schroeder, Simón Méndez-Ferrer, Radek C. Skoda
Journal: Blood Advances
Blood Adv (2024) 8 (5): 1234–1249.
https://doi.org/10.1182/bloodadvances.2023011338
Published: 2024
Includes: Supplemental data
Journal Articles

SAKK 35/15: a phase 1 trial of obinutuzumab in combination with venetoclax in patients with previously untreated follicular lymphoma

Clinical Trials & Observations
Anastasios Stathis, Ulrich Mey, Sämi Schär, Felicitas Hitz, Christiane Pott, Nicolas Mach, Fatime Krasniqi, Urban Novak, Christian Schmidt, Karin Hohloch, Dirk Lars Kienle, Dagmar Hess, Alden A. Moccia, Michael Unterhalt, Katrin Eckhardt, Stefanie Hayoz, Gabriela Forestieri, Davide Rossi, Stefan Dirnhofer, Luca Ceriani, Giulio Sartori, Francesco Bertoni, Christian Buske, Emanuele Zucca, Wolfgang Hiddemann
Journal: Blood Advances
Blood Adv (2022) 6 (13): 3911–3920.
https://doi.org/10.1182/bloodadvances.2021006520
Published: 2022
Includes: Supplemental data
Journal Articles

Enhanced engraftment of human myelofibrosis stem and progenitor cells in MISTRG mice

Veronika Lysenko, Nicole Wildner-Verhey van Wijk, Kathrin Zimmermann, Marie-Christine Weller, Marco Bühler, Mattheus H. E. Wildschut, Patrick Schürch, Christine Fritz, Ulrich Wagner, Laura Calabresi, Bethan Psaila, Richard A. Flavell, Alessandro M. Vannucchi, Adam J. Mead, Peter J. Wild, Stefan Dirnhofer, Markus G. Manz, Alexandre P. A. Theocharides
Journal: Blood Advances
Blood Adv (2020) 4 (11): 2477–2488.
https://doi.org/10.1182/bloodadvances.2019001364
Published: 2020
Includes: Supplemental data
Journal Articles

SAKK38/07 study: integration of baseline metabolic heterogeneity and metabolic tumor volume in DLBCL prognostic model

Clinical Trials & Observations
Luca Ceriani, Giuseppe Gritti, Luciano Cascione, Maria Cristina Pirosa, Angela Polino, Teresa Ruberto, Anastasios Stathis, Andrea Bruno, Alden A. Moccia, Luca Giovanella, Stefanie Hayoz, Sämi Schär, Stefan Dirnhofer, Alessandro Rambaldi, Giovanni Martinelli, Christoph Mamot, Emanuele Zucca
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1082–1092.
https://doi.org/10.1182/bloodadvances.2019001201
Published: 2020