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Journal Articles

IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2 -mutant hematopoietic stem cells

Shivam Rai, Yang Zhang, Elodie Grockowiak, Quentin Kimmerlin, Nils Hansen, Cedric B. Stoll, Marc Usart, Damien Luque Paz, Hui Hao-Shen, Yexuan Zhu, Julien Roux, Michael S. Bader, Stefan Dirnhofer, Christopher J. Farady, Timm Schroeder, Simón Méndez-Ferrer, Radek C. Skoda
Journal: Blood Advances
Blood Adv (2024) 8 (5): 1234–1249.
https://doi.org/10.1182/bloodadvances.2023011338
Published: 2024
Includes: Supplemental data
Journal Articles

PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma

Clinical Trials & Observations
Fiona Brown-Burke, Inah Hwang, Shelby Sloan, Claire Hinterschied, JoBeth Helmig-Mason, Mackenzie Long, Wing Keung Chan, Alexander Prouty, Ji-Hyun Chung, Yang Zhang, Satishkumar Singh, Youssef Youssef, Neha Bhagwat, Zhengming Chen, Selina Chen-Kiang, Maurizio Di Liberto, Olivier Elemento, Lalit Sehgal, Lapo Alinari, Kris Vaddi, Peggy Scherle, Rosa Lapalombella, Jihye Paik, Robert A. Baiocchi
Journal: Blood Advances
Blood Adv (2023) 7 (20): 6211–6224.
https://doi.org/10.1182/bloodadvances.2023009906
Published: 2023
Includes: Supplemental data
Journal Articles

Orelabrutinib for the treatment of relapsed or refractory MCL: a phase 1/2, open-label, multicenter, single-arm study

Clinical Trials & Observations
Li-Juan Deng, Ke-Shu Zhou, Li-Hong Liu, Ming-Zhi Zhang, Zhi-Ming Li, Chun-Yan Ji, Wei Xu, Ting Liu, Bing Xu, Xin Wang, Su-Jun Gao, Hui-Lai Zhang, Yu Hu, Yan Li, Ying Cheng, Hai-Yan Yang, Jun-Ning Cao, Zun-Min Zhu, Jian-Da Hu, Wei Zhang, Hong-Mei Jing, Kai-Yang Ding, Xiang-Yang Zhang, Ren-Bin Zhao, Bin Zhang, Ya-Min Tian, Yong-Ping Song, Yu-Qin Song, Jun Zhu
Journal: Blood Advances
Blood Adv (2023) 7 (16): 4349–4357.
https://doi.org/10.1182/bloodadvances.2022009168
Published: 2023
Includes: Supplemental data