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Issue Archive

Volume 2, Issue 22
November 27 2018
Issue Cover

Table of Contents

EDITORIAL

The value of clinical practice guidelines in hematology
Julie A. Panepinto,Menaka Pai
View Articletitled, The value of clinical practice guidelines in hematology

CLINICAL GUIDELINES

American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients
Holger J. Schünemann,Mary Cushman,Allison E. Burnett,Susan R. Kahn,Jan Beyer-Westendorf,Frederick A. Spencer,Suely M. Rezende,Neil A. Zakai,Kenneth A. Bauer,Francesco Dentali,Jill Lansing,Sara Balduzzi,Andrea Darzi,Gian Paolo Morgano,Ignacio Neumann,Robby Nieuwlaat,Juan J. Yepes-Nuñez,Yuan Zhang,Wojtek Wiercioch
View Articletitled, American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients
Supplemental data
American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism
Wendy Lim,Grégoire Le Gal,Shannon M. Bates,Marc Righini,Linda B. Haramati,Eddy Lang,Jeffrey A. Kline,Sonja Chasteen,Marcia Snyder,Payal Patel,Meha Bhatt,Parth Patel,Cody Braun,Housne Begum,Wojtek Wiercioch,Holger J. Schünemann,Reem A. Mustafa
View Articletitled, American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism
Supplemental data
American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy
Daniel M. Witt,Robby Nieuwlaat,Nathan P. Clark,Jack Ansell,Anne Holbrook,Jane Skov,Nadine Shehab,Juliet Mock,Tarra Myers,Francesco Dentali,Mark A. Crowther,Arnav Agarwal,Meha Bhatt,Rasha Khatib,John J. Riva,Yuan Zhang,Gordon Guyatt
View Articletitled, American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy
Supplemental data
American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism
Paul Monagle,Carlos A. Cuello,Caitlin Augustine,Mariana Bonduel,Leonardo R. Brandão,Tammy Capman,Anthony K. C. Chan,Sheila Hanson,Christoph Male,Joerg Meerpohl,Fiona Newall,Sarah H. O’Brien,Leslie Raffini,Heleen van Ommen,John Wiernikowski,Suzan Williams,Meha Bhatt,John J. Riva,Yetiani Roldan,Nicole Schwab,Reem A. Mustafa,Sara K. Vesely
View Articletitled, American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism
Supplemental data
American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy
Shannon M. Bates,Anita Rajasekhar,Saskia Middeldorp,Claire McLintock,Marc A. Rodger,Andra H. James,Sara R. Vazquez,Ian A. Greer,John J. Riva,Meha Bhatt,Nicole Schwab,Danielle Barrett,Andrea LaHaye,Bram Rochwerg
View Articletitled, American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy
Supplemental data
American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia
Adam Cuker,Gowthami M. Arepally,Beng H. Chong,Douglas B. Cines,Andreas Greinacher,Yves Gruel,Lori A. Linkins,Stephen B. Rodner,Sixten Selleng,Theodore E. Warkentin,Ashleigh Wex,Reem A. Mustafa,Rebecca L. Morgan,Nancy Santesso
View Articletitled, American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia
Supplemental data

EXCEPTIONAL CASE REPORT

Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease
Clinical Trials & Observations
Satoshi Kaito,Takashi Toya,Kota Yoshifuji,Shuhei Kurosawa,Kyoko Inamoto,Kozue Takeshita,Wataru Suda,Kazuhiko Kakihana,Kenya Honda,Masahira Hattori,Kazuteru Ohashi
View Articletitled, Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease
Supplemental data

REVIEW ARTICLES

No free rides: management of toxicities of novel immunotherapies in ALL, including financial
Clinical Trials & Observations
Tania Jain,Mark R. Litzow
View Articletitled, No free rides: management of toxicities of novel immunotherapies in ALL, including financial
Clinical consequences of clonal hematopoiesis of indeterminate potential
David P. Steensma
View Articletitled, Clinical consequences of clonal hematopoiesis of indeterminate potential
GVHD: biology matters
Clinical Trials & Observations
James L. M. Ferrara,Mohammed S. Chaudhry
View Articletitled, GVHD: biology matters

CLINICAL TRIALS AND OBSERVATIONS

Onsets of progression and second treatment determine survival of patients with symptomatic Waldenström macroglobulinemia
Clinical Trials & Observations
Stephanie Guidez,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Julien Labreuche,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Elodie Drumez,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Loic Ysebaert,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Jana Bakala,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Caroline Delette,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Bénédicte Hivert,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Caroline Protin,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Hervé Declercq,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Mélanie Verlay,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Jean Pierre Marolleau,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Alain Duhamel,on behalf of the French Innovative Leukemia Organization (FILO) CLL group,Pierre Morel,on behalf of the French Innovative Leukemia Organization (FILO) CLL group
View Articletitled, Onsets of progression and second treatment determine survival of patients with symptomatic Waldenström macroglobulinemia
Supplemental data
Prospective comparison of the HEP score and 4Ts score for the diagnosis of heparin-induced thrombocytopenia
Clinical Trials & Observations
Allyson M. Pishko,Sara Fardin,Daniel S. Lefler,Koosha Paydary,Rolando Vega,Gowthami M. Arepally,Mark Crowther,Lawrence Rice,Douglas B. Cines,Adam Cuker
View Articletitled, Prospective comparison of the HEP score and 4Ts score for the diagnosis of heparin-induced thrombocytopenia
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

CD19-positive antibody-secreting cells provide immune memory
C. J. Groves,J. Carrell,R. Grady,B. Rajan,C. A. Morehouse,R. Halpin,J. Wang,J. Wu,Y. Shrestha,R. Rayanki,R. Kolbeck,Y. Wang,R. Herbst
View Articletitled, CD19-positive antibody-secreting cells provide immune memory
Supplemental data
IL-15/IL-15Rα/CD80-expressing AML cell vaccines eradicate minimal residual disease in leukemic mice
Yimin Shi,Lillia Dincheva-Vogel,Charles E. Ayemoba,Jeffrey P. Fung,Cristina Bergamaschi,George N. Pavlakis,Farzin Farzaneh,Karin M. L. Gaensler
View Articletitled, IL-15/IL-15Rα/CD80-expressing AML cell vaccines eradicate minimal residual disease in leukemic mice
Supplemental data

LYMPHOID NEOPLASIA

Plasma cell proliferative index is an independent predictor of progression in smoldering multiple myeloma
Clinical Trials & Observations
Mohammed A. Aljama,M. Hasib Sidiqi,Arjun Lakshman,Angela Dispenzieri,Dragan Jevremovic,Morie A. Gertz,Martha Q. Lacy,Francis K. Buadi,David Dingli,Eli Muchtar,Amie L. Fonder,Suzanne R. Hayman,Miriam A. Hobbs,Wilson I. Gonsalves,Rahma Warsame,Taxiarchis V. Kourelis,Yi Lisa Hwa,Prashant Kapoor,Nelson Leung,Ronald S. Go,Robert A. Kyle,S. Vincent Rajkumar,Shaji K. Kumar
View Articletitled, Plasma cell proliferative index is an independent predictor of progression in smoldering multiple myeloma

MYELOID NEOPLASIA

NPM1 mutated AML can relapse with wild-type NPM1: persistent clonal hematopoiesis can drive relapse
Clinical Trials & Observations
Alexander Höllein,Manja Meggendorfer,Frank Dicker,Sabine Jeromin,Niroshan Nadarajah,Wolfgang Kern,Claudia Haferlach,Torsten Haferlach
View Articletitled, <em>NPM1</em> mutated AML can relapse with wild-type <em>NPM1</em>: persistent clonal hematopoiesis can drive relapse
HoxA9 transforms murine myeloid cells by a feedback loop driving expression of key oncogenes and cell cycle control genes
Xiaoxia Zhong,Andreas Prinz,Julia Steger,Maria-Paz Garcia-Cuellar,Markus Radsak,Abderrazzak Bentaher,Robert K. Slany
View Articletitled, HoxA9 transforms murine myeloid cells by a feedback loop driving expression of key oncogenes and cell cycle control genes
Supplemental data

THROMBOSIS AND HEMOSTASIS

Prognostic value of D-dimer and markers of coagulation for stratification of abdominal aortic aneurysm growth
Clinical Trials & Observations
Alexandra C. Sundermann,Keith Saum,Kelsey A. Conrad,Hannah M. Russell,Todd L. Edwards,Kevin Mani,Martin Björck,Anders Wanhainen,A. Phillip Owens, III
View Articletitled, Prognostic value of D-dimer and markers of coagulation for stratification of abdominal aortic aneurysm growth
Supplemental data
Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice
Rikke Stagaard,Carsten Dan Ley,Kasper Almholt,Lisbeth Høier Olsen,Tom Knudsen,Matthew J. Flick
View Articletitled, Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice

GLOBAL ADVANCES

Intima-media thickness of the common femoral artery as a marker of leg ulceration in sickle cell disease patients
Clinical Trials & Observations Global Advances
Oluwagbemiga O. Ayoola,Rahman A. Bolarinwa,Uvie U. Onakpoya,Tewogbade A. Adedeji,Chidiogo C. Onwuka,Bukunmi M. Idowu
View Articletitled, Intima-media thickness of the common femoral artery as a marker of leg ulceration in sickle cell disease patients

COMMENTARY

Comment on model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients
Clinical Trials & Observations
Stefan Willmann,Liping Zhang,Hannah Mayer,Hans-Ulrich Siegmund,Takahiko Tanigawa,Masato Kaneko,Gary Peters,Jeffrey I. Weitz,Scott D. Berkowitz,Rolf Burghaus
View Articletitled, Comment on model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Model for clonal hematopoiesis driving relapse or secondary leukemia. The first leukemia is cured by chemotherapy based on the underlying clonal hematopoiesis. A second driver mutation then leads to overt relapse. See the article by Höllein et al.

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