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Volume 2, Issue 16

August 28 2018

In this Issue

EXCEPTIONAL CASE REPORT
STIMULUS REPORT
REVIEW ARTICLE
CLINICAL TRIALS AND OBSERVATIONS
LYMPHOID NEOPLASIA
MYELOID NEOPLASIA
PLATELETS AND THROMBOPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION

EXCEPTIONAL CASE REPORT

Long-term disease control of Langerhans cell histiocytosis using combined BRAF and MEK inhibition
Clinical Trials & Observations

Gil Awada,Teofila Seremet,Karel Fostier,Hendrik Everaert,Bart Neyns

View Articletitled, Long-term disease control of Langerhans cell histiocytosis using combined BRAF and MEK inhibition

STIMULUS REPORT

TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice

Christopher W. Smith,Zaher Raslan,Lola Parfitt,Abdullah O. Khan,Pushpa Patel,Yotis A. Senis,Alexandra Mazharian

View Articletitled, TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice

Supplemental data

REVIEW ARTICLE

Antiviral prophylaxis for cytomegalovirus infection in allogeneic hematopoietic cell transplantation
Clinical Trials & Observations

Kaiwen Chen,Matthew P. Cheng,Sarah P. Hammond,Hermann Einsele,Francisco M. Marty

View Articletitled, Antiviral prophylaxis for cytomegalovirus infection in allogeneic hematopoietic cell transplantation

Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia
Clinical Trials & Observations

Brian Ball,Rami S. Komrokji,Lionel Adès,Mikkael A. Sekeres,Amy E. DeZern,Lisa Pleyer,Norbert Vey,Antonio Almeida,Ulrich Germing,Thomas Cluzeau,Uwe Platzbecker,Steven D. Gore,Pierre Fenaux,Thomas Prebet

View Articletitled, Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia

Supplemental data

LYMPHOID NEOPLASIA

Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma

Jimmy Lee,Liang Leo Zhang,Wenjun Wu,Hui Guo,Yan Li,Madina Sukhanova,Girish Venkataraman,Shengjian Huang,Hui Zhang,Mir Alikhan,Pin Lu,Ailin Guo,Natalie Galanina,Jorge Andrade,Michael L. Wang,Y. Lynn Wang

View Articletitled, Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma

Supplemental data

Single-cell heterogeneity in Sézary syndrome

Terkild Brink Buus,Andreas Willerslev-Olsen,Simon Fredholm,Edda Blümel,Claudia Nastasi,Maria Gluud,Tengpeng Hu,Lise M. Lindahl,Lars Iversen,Hanne Fogh,Robert Gniadecki,Ivan V. Litvinov,Jenny L. Persson,Charlotte Menné Bonefeld,Carsten Geisler,Jan Pravsgaard Christensen,Thorbjørn Krejsgaard,Thomas Litman,Anders Woetmann,Niels Ødum

View Articletitled, Single-cell heterogeneity in Sézary syndrome

Supplemental data

MYELOID NEOPLASIA

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes
Clinical Trials & Observations

Raphael Itzykson,Simon Crouch,Erica Travaglino,Alex Smith,Argiris Symeonidis,Eva Hellström-Lindberg,Guillermo Sanz,Jaroslav Čermák,Reinhard Stauder,Chiara Elena,Ulrich Germing,Moshe Mittelman,Saskia Langemeijer,Krzysztof Mądry,Aurelia Tatic,Mette Skov Holm,Antonio Medina Almeida,Aleksandar Savic,Njetočka Gredelj Šimec,Elisa Luño,Dominic Culligan,Agnes Guerci-Bresler,Luca Malcovati,Corine van Marrewijk,David Bowen,Theo de Witte,Pierre Fenaux,on behalf of the European MDS Registry members

View Articletitled, Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes

Supplemental data

PLATELETS AND THROMBOPOIESIS

Complement-mediated thrombotic microangiopathy associated with lupus nephritis

Mi Hee Park,Nicholas Caselman,Scott Ulmer,Ilene Ceil Weitz

View Articletitled, Complement-mediated thrombotic microangiopathy associated with lupus nephritis

THROMBOSIS AND HEMOSTASIS

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

Manu T. Kalathottukaren,A. Louise Creagh,Srinivas Abbina,Genmin Lu,Mark J. Karbarz,Anjali Pandey,Pamela B. Conley,Jayachandran N. Kizhakkedathu,Charles Haynes

View Articletitled, Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

Supplemental data

The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B
Clinical Trials & Observations

J. Michael Soucie,for the US Hemophilia Treatment Center Network,Paul E. Monahan,for the US Hemophilia Treatment Center Network,Roshni Kulkarni,for the US Hemophilia Treatment Center Network,Barbara A. Konkle,for the US Hemophilia Treatment Center Network,Marshall A. Mazepa,for the US Hemophilia Treatment Center Network

View Articletitled, The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B

RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists

Peisong Ma,Shuchi Gupta,Sara Sampietro,Daniel DeHelian,Valerie Tutwiler,Alan Tang,Timothy J. Stalker,Lawrence F. Brass

View Articletitled, RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists

Supplemental data

TRANSPLANTATION

Computational modeling and confirmation of leukemia-associated minor histocompatibility antigens

Jefferson L. Lansford,Udara Dharmasiri,Shengjie Chai,Sally A. Hunsucker,Dante S. Bortone,James E. Keating,Ian M. Schlup,Gary L. Glish,Edward J. Collins,Gheath Alatrash,Jeffrey J. Molldrem,Paul M. Armistead,Benjamin G. Vincent

View Articletitled, Computational modeling and confirmation of leukemia-associated minor histocompatibility antigens

Supplemental data

Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity
Clinical Trials & Observations

Mary Eapen,Ruta Brazauskas,Michael Hemmer,Waleska S. Perez,Patricia Steinert,Mary M. Horowitz,H. Joachim Deeg

View Articletitled, Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity

Conditioning intensity in secondary AML with prior myelodysplastic syndrome/myeloproliferative disorders: an EBMT ALWP study
Clinical Trials & Observations

Salyka Sengsayadeth,Katie S. Gatwood,Ariane Boumendil,Myriam Labopin,Jürgen Finke,Arnold Ganser,Matthias Stelljes,Gerhard Ehninger,Dietrich Beelen,Dietger Niederwieser,Didier Blaise,Peter Dreger,Ghulam Mufti,Patrice Chevallier,Audrey Mailhol,Maria H. Gilleece,Norbert Gorin,Jordi Esteve,Fabio Ciceri,Frederic Baron,Christoph Schmid,Sebastian Giebel,Mohamad Mohty,Bipin N. Savani,Arnon Nagler

View Articletitled, Conditioning intensity in secondary AML with prior myelodysplastic syndrome/myeloproliferative disorders: an EBMT ALWP study

Cover Image

Cover Image

COVER FIGURE
A schematic of the computational method used to predict leukemia associated with minor histocompatibility antigens. A new leukemia associated with a minor antigen derived from GRK4 was subsequently discovered using targeted mass spectrometry and tetramer analysis in posttransplant patient samples. See the article by Lansford et al.
Front Matter
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Table of Contents

EXCEPTIONAL CASE REPORT

Long-term disease control of Langerhans cell histiocytosis using combined BRAF and MEK inhibition
Clinical Trials & Observations

STIMULUS REPORT

TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice

REVIEW ARTICLE

Antiviral prophylaxis for cytomegalovirus infection in allogeneic hematopoietic cell transplantation
Clinical Trials & Observations

CLINICAL TRIALS AND OBSERVATIONS

Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia
Clinical Trials & Observations

LYMPHOID NEOPLASIA

Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma

Single-cell heterogeneity in Sézary syndrome

MYELOID NEOPLASIA

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes
Clinical Trials & Observations

PLATELETS AND THROMBOPOIESIS

Complement-mediated thrombotic microangiopathy associated with lupus nephritis

THROMBOSIS AND HEMOSTASIS

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B
Clinical Trials & Observations

RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists

TRANSPLANTATION

Computational modeling and confirmation of leukemia-associated minor histocompatibility antigens

Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity
Clinical Trials & Observations

Conditioning intensity in secondary AML with prior myelodysplastic syndrome/myeloproliferative disorders: an EBMT ALWP study
Clinical Trials & Observations

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ASH Publications

American Society of Hematology

Issue Archive

Table of Contents

EXCEPTIONAL CASE REPORT

Long-term disease control of Langerhans cell histiocytosis using combined BRAF and MEK inhibition Clinical Trials & Observations

STIMULUS REPORT

TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice

REVIEW ARTICLE

Antiviral prophylaxis for cytomegalovirus infection in allogeneic hematopoietic cell transplantation Clinical Trials & Observations

CLINICAL TRIALS AND OBSERVATIONS

Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia Clinical Trials & Observations

LYMPHOID NEOPLASIA

Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma

Single-cell heterogeneity in Sézary syndrome

MYELOID NEOPLASIA

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes Clinical Trials & Observations

PLATELETS AND THROMBOPOIESIS

Complement-mediated thrombotic microangiopathy associated with lupus nephritis

THROMBOSIS AND HEMOSTASIS

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B Clinical Trials & Observations

RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists

TRANSPLANTATION

Computational modeling and confirmation of leukemia-associated minor histocompatibility antigens

Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity Clinical Trials & Observations

Conditioning intensity in secondary AML with prior myelodysplastic syndrome/myeloproliferative disorders: an EBMT ALWP study Clinical Trials & Observations

Cover Image

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

Long-term disease control of Langerhans cell histiocytosis using combined BRAF and MEK inhibition
Clinical Trials & Observations

Antiviral prophylaxis for cytomegalovirus infection in allogeneic hematopoietic cell transplantation
Clinical Trials & Observations

Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia
Clinical Trials & Observations

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes
Clinical Trials & Observations

The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B
Clinical Trials & Observations

Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity
Clinical Trials & Observations

Conditioning intensity in secondary AML with prior myelodysplastic syndrome/myeloproliferative disorders: an EBMT ALWP study
Clinical Trials & Observations