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Issue Archive

Volume 1, Issue 24
November 14 2017
Issue Cover

Table of Contents

BLOOD ADVANCES TALK

ITP and thrombosis: an intriguing association
Francesco Rodeghiero
View Articletitled, ITP and thrombosis: an intriguing association
Supplemental data

EXCEPTIONAL CASE REPORT

Management of thrombotic thrombocytopenic purpura without plasma exchange: the Jehovah’s Witness experience
Clinical Trials & Observations
James N. George,Steven A. Sandler,Joanna Stankiewicz
View Articletitled, Management of thrombotic thrombocytopenic purpura without plasma exchange: the Jehovah’s Witness experience

STIMULUS REPORT

Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia
Clinical Trials & Observations
Karine Darbinyan,Aditi Shastri,Anjali Budhathoki,Daniel Helbig,Rose Snyder,Kith Pradhan,Junaid Saleh-Esa,Noah S. Kornblum,Adam F. Binder,Swati Goel,Murali Janakiram,Olga Derman,Kira Gritsman,Ulrich Steidl,Ira Braunschweig,Amit Verma,Ioannis Mantzaris
View Articletitled, Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia

REVIEW ARTICLES

The role of targeted therapy in the management of patients with AML
Clinical Trials & Observations
Alexander E. Perl
View Articletitled, The role of targeted therapy in the management of patients with AML
Management of newly diagnosed immune thrombocytopenia: can we change outcomes?
Cindy E. Neunert
View Articletitled, Management of newly diagnosed immune thrombocytopenia: can we change outcomes?

CLINICAL TRIALS AND OBSERVATIONS

Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myeloma: a population-based study
Clinical Trials & Observations
Marianna Thordardottir,Ebba K. Lindqvist,Sigrun H. Lund,Rene Costello,Debra Burton,Neha Korde,Sham Mailankody,Gudny Eiriksdottir,Lenore J. Launer,Vilmundur Gudnason,Tamara B. Harris,Ola Landgren,Sigurdur Y. Kristinsson
View Articletitled, Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myeloma: a population-based study
Long-term control of recurrent or refractory viral infections after allogeneic HSCT with third-party virus-specific T cells
Clinical Trials & Observations
Barbara Withers,Emily Blyth,Leighton E. Clancy,Agnes Yong,Chris Fraser,Jane Burgess,Renee Simms,Rebecca Brown,David Kliman,Ming-Celine Dubosq,David Bishop,Gaurav Sutrave,Chun Kei Kris Ma,Peter J. Shaw,Kenneth P. Micklethwaite,David J. Gottlieb
View Articletitled, Long-term control of recurrent or refractory viral infections after allogeneic HSCT with third-party virus-specific T cells
Supplemental data
Circulating fibrocytes as biomarkers of impaired lung function in adults with sickle cell disease
Clinical Trials & Observations
Borna Mehrad,Marie D. Burdick,Nancy J. Wandersee,Kaushik S. Shahir,Liyun Zhang,Pippa M. Simpson,Robert M. Strieter,Joshua J. Field
View Articletitled, Circulating fibrocytes as biomarkers of impaired lung function in adults with sickle cell disease
Supplemental data

HEALTH SERVICES AND OUTCOMES

Patients’ priorities in selecting chronic lymphocytic leukemia treatments
Carol Mansfield,Anthony Masaquel,Jessie Sutphin,Elisa Weiss,Meghan Gutierrez,Jennifer Wilson,Marco Boeri,Jia Li,Carolina Reyes
View Articletitled, Patients’ priorities in selecting chronic lymphocytic leukemia treatments
Supplemental data

HEMATOPOIESIS AND STEM CELLS

A knock-in mouse strain facilitates dynamic tracking and enrichment of MEIS1
Ping Xiang,Wei Wei,Nicole Hofs,Jack Clemans-Gibbon,Tobias Maetzig,Courteney K. Lai,Ishpreet Dhillon,Christopher May,Jens Ruschmann,Edith Schneider,Patricia Rosten,Kaiji Hu,Florian Kuchenbauer,Pamela A. Hoodless,R. Keith Humphries
View Articletitled, A knock-in mouse strain facilitates dynamic tracking and enrichment of MEIS1
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

TAK1 inhibition subverts the osteoclastogenic action of TRAIL while potentiating its antimyeloma effects
Hirofumi Tenshin,Jumpei Teramachi,Asuka Oda,Ryota Amachi,Masahiro Hiasa,Ariunzaya Bat-Erdene,Keiichiro Watanabe,Masami Iwasa,Takeshi Harada,Shiro Fujii,Kumiko Kagawa,Kimiko Sogabe,Shingen Nakamura,Hirokazu Miki,Kiyoe Kurahashi,Sumiko Yoshida,Kenichi Aihara,Itsuro Endo,Eiji Tanaka,Toshio Matsumoto,Masahiro Abe
View Articletitled, TAK1 inhibition subverts the osteoclastogenic action of TRAIL while potentiating its antimyeloma effects
Supplemental data

LYMPHOID NEOPLASIA

Redefining the role of etoposide in first-line treatment of peripheral T-cell lymphoma
Clinical Trials & Observations
Young Ae Kim,Ja Min Byun,Keeho Park,Gi Hwan Bae,Dukhyoung Lee,Dong Sook Kim,Sung-Soo Yoon,Youngil Koh
View Articletitled, Redefining the role of etoposide in first-line treatment of peripheral T-cell lymphoma
Supplemental data
BRAFV600E accelerates disease progression and enhances immune suppression in a mouse model of B-cell leukemia
Yo-Ting Tsai,Aparna Lakshmanan,Amy Lehman,Bonnie K. Harrington,Fabienne McClanahan Lucas,Minh Tran,Ellen J. Sass,Meixiao Long,Alan D. Flechtner,Florinda Jaynes,Krista La Perle,Vincenzo Coppola,Gerard Lozanski,Natarajan Muthusamy,John C. Byrd,Michael R. Grever,David M. Lucas
View Articletitled, BRAF<sup>V600E</sup> accelerates disease progression and enhances immune suppression in a mouse model of B-cell leukemia
Supplemental data
Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma
Hanna Karvonen,David Chiron,Wilhelmiina Niininen,Sara Ek,Mats Jerkeman,Elaheh Moradi,Matti Nykter,Caroline A. Heckman,Olli Kallioniemi,Astrid Murumägi,Daniela Ungureanu
View Articletitled, Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma
Supplemental data

TRANSPLANTATION

Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates
Jean Kwun,Christopher Burghuber,Miriam Manook,Brian Ezekian,Jaeberm Park,Janghoon Yoon,John S. Yi,Neal Iwakoshi,Adriana Gibby,Jung Joo Hong,Alton B. Farris,Allan D. Kirk,Stuart J. Knechtle
View Articletitled, Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates
Supplemental data
Immune tolerance induction by nonmyeloablative haploidentical HSCT combining T-cell depletion and posttransplant cyclophosphamide
Clinical Trials & Observations
Franco Aversa,Esther Bachar-Lustig,Noga Or-Geva,Lucia Prezioso,Sabrina Bonomini,Ilenia Manfra,Alessandro Monti,Chiara Schifano,Yael Zlotnikov-Klionsky,Massimo F. Martelli,Gabriella Sammarelli,Maria Sassi,Maurizio Soli,Silvia Giuliodori,Magda Benecchi,Nicola Giuliani,Frank Lohr,Silvia Pratissoli,Yair Reisner
View Articletitled, Immune tolerance induction by nonmyeloablative haploidentical HSCT combining T-cell depletion and posttransplant cyclophosphamide
Supplemental data
Cord blood transplantation recapitulates fetal ontogeny with a distinct molecular signature that supports CD4+ T-cell reconstitution
Prashant Hiwarkar,Mike Hubank,Waseem Qasim,Robert Chiesa,Kimberly C. Gilmour,Aurore Saudemont,Persis J. Amrolia,Paul Veys
View Articletitled, Cord blood transplantation recapitulates fetal ontogeny with a distinct molecular signature that supports CD4<sup>+</sup> T-cell reconstitution
Supplemental data
Quality of life of Hurler syndrome patients after successful hematopoietic stem cell transplantation
Clinical Trials & Observations
Mieke Aldenhoven,Brigitte T. A. van den Broek,Robert F. Wynn,Anne O’Meara,Paul Veys,Attilio Rovelli,Simon A. Jones,Rossella Parini,Peter M. van Hasselt,Marleen Renard,Victoria Bordon,Tom J. de Koning,Jaap Jan Boelens
View Articletitled, Quality of life of Hurler syndrome patients after successful hematopoietic stem cell transplantation
Supplemental data
Chronic disease burden and frailty in survivors of childhood HSCT: a report from the St. Jude Lifetime Cohort Study
Clinical Trials & Observations
Hesham M. Eissa,Lu Lu,Malek Baassiri,Nickhill Bhakta,Matthew J. Ehrhardt,Brandon M. Triplett,Daniel M. Green,Daniel A. Mulrooney,Leslie L. Robison,Melissa M. Hudson,Kirsten K. Ness
View Articletitled, Chronic disease burden and frailty in survivors of childhood HSCT: a report from the St. Jude Lifetime Cohort Study
Supplemental data
Tandem autologous/allogeneic hematopoietic cell transplantation with bortezomib maintenance therapy for high-risk myeloma
Clinical Trials & Observations
Damian J. Green,David G. Maloney,Barry E. Storer,Brenda M. Sandmaier,Leona A. Holmberg,Pamela S. Becker,Min Fang,Paul J. Martin,George E. Georges,Michelle E. Bouvier,Rainer Storb,Marco Mielcarek
View Articletitled, Tandem autologous/allogeneic hematopoietic cell transplantation with bortezomib maintenance therapy for high-risk myeloma
Vaccination with autologous myeloblasts admixed with GM-K562 cells in patients with advanced MDS or AML after allogeneic HSCT
Clinical Trials & Observations
Vincent T. Ho,Haesook T. Kim,Natalie Bavli,Martin Mihm,Olga Pozdnyakova,Matthias Piesche,Heather Daley,Carol Reynolds,Nicholas C. Souders,Corey Cutler,John Koreth,Edwin P. Alyea,Joseph H. Antin,Jerome Ritz,Glenn Dranoff,Robert J. Soiffer
View Articletitled, Vaccination with autologous myeloblasts admixed with GM-K562 cells in patients with advanced MDS or AML after allogeneic HSCT
Supplemental data
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Peripheral lymph nodes biopsied before and after desensitization with dual targeting. Dual targeting desensitization treatment (bortezomib, belatacept, and anti-CD40 monoclonal antibody) significantly reduced germinal centers in sensitized nonhuman primates. See the article by Kwun et al.

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