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Natarajan Muthusamy
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Journal Articles

A CD3 humanized mouse model unmasked unique features of T-cell responses to bispecific antibody treatment

Lingling Wang, Vincent Leach, Natarajan Muthusamy, John Byrd, Meixiao Long
Journal: Blood Advances
Blood Adv (2024) 8 (2): 470–481.
https://doi.org/10.1182/bloodadvances.2023010971
Published: 2024
Includes: Supplemental data
Journal Articles

Evaluation of allogeneic and autologous membrane-bound IL-21–expanded NK cells for chronic lymphocytic leukemia therapy

Max Yano, Chia Sharpe, J. Rachel Lance, Janani Ravikrishnan, Kevan Zapolnik, Xiaokui Mo, Jennifer A. Woyach, Deepa Sampath, Adam S. Kittai, Sumithira Vasu, Seema Bhat, Kerry A. Rogers, Dean A. Lee, Natarajan Muthusamy, John C. Byrd
Journal: Blood Advances
Blood Adv (2022) 6 (20): 5641–5654.
https://doi.org/10.1182/bloodadvances.2021005883
Published: 2022
Includes: Supplemental data
Journal Articles

Differential regulation of CTLA4 expression through BTK-dependent and independent mechanisms in CLL

Max Yano, Jessica Nunes, Xiaokui Mo, Kerry A. Rogers, Jennifer A. Woyach, John C. Byrd, Natarajan Muthusamy
Journal: Blood Advances
Blood Adv (2022) 6 (18): 5440–5448.
https://doi.org/10.1182/bloodadvances.2021005571
Published: 2022
Journal Articles

The ROR1 antibody-drug conjugate huXBR1-402-G5-PNU effectively targets ROR1 + leukemia

Eileen Y. Hu, Priscilla Do, Swagata Goswami, Jessica Nunes, Chi-ling Chiang, Sara Elgamal, Ann M. Ventura, Carolyn Cheney, Kevan Zapolnik, Erich Williams, Rajeswaran Mani, Frank Frissora, Xiaokui Mo, Lorenz Waldmeier, Roger R. Beerli, Haiyong Peng, Christoph Rader, Meixiao Long, Ulf Grawunder, John C. Byrd, Natarajan Muthusamy
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3152–3162.
https://doi.org/10.1182/bloodadvances.2020003276
Published: 2021
Includes: Supplemental data
Journal Articles

Par-4 overexpression impedes leukemogenesis in the Eµ-TCL1 leukemia model through downregulation of NF-κB signaling

J. T. Greene, Rajeswaran Mani, Rahul Ramaswamy, Frank Frissora, Max Yano, Kevan Zapolnik, Bonnie Harrington, Ronni Wasmuth, Minh Tran, Xiaokui Mo, Mary McKenna, Vivek M. Rangnekar, John C. Byrd, Subbarao Bondada, Natarajan Muthusamy
Journal: Blood Advances
Blood Adv (2019) 3 (8): 1255–1266.
https://doi.org/10.1182/bloodadvances.2018025973
Published: 2019
Includes: Supplemental data
Journal Articles

Anti–BAFF-R antibody VAY-736 demonstrates promising preclinical activity in CLL and enhances effectiveness of ibrutinib

Emily M. McWilliams, Christopher R. Lucas, Timothy Chen, Bonnie K. Harrington, Ronni Wasmuth, Amanda Campbell, Kerry A. Rogers, Carolyn M. Cheney, Xiaokui Mo, Leslie A. Andritsos, Farrukh T. Awan, Jennifer Woyach, William E. Carson, III, Jonathan Butchar, Susheela Tridandapani, Erin Hertlein, Carlos E. Castro, Natarajan Muthusamy, John C. Byrd
Journal: Blood Advances
Blood Adv (2019) 3 (3): 447–460.
https://doi.org/10.1182/bloodadvances.2018025684
Published: 2019
Includes: Supplemental data
Journal Articles

BRAF V600E accelerates disease progression and enhances immune suppression in a mouse model of B-cell leukemia

Yo-Ting Tsai, Aparna Lakshmanan, Amy Lehman, Bonnie K. Harrington, Fabienne McClanahan Lucas, Minh Tran, Ellen J. Sass, Meixiao Long, Alan D. Flechtner, Florinda Jaynes, Krista La Perle, Vincenzo Coppola, Gerard Lozanski, Natarajan Muthusamy, John C. Byrd, Michael R. Grever, David M. Lucas
Journal: Blood Advances
Blood Adv (2017) 1 (24): 2147–2160.
https://doi.org/10.1182/bloodadvances.2017006593
Published: 2017
Includes: Supplemental data