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Journal Articles

Progression signature underlies clonal evolution and dissemination of multiple myeloma

Yu Jia Shen, Yuji Mishima, Jiantao Shi, Romanos Sklavenitis-Pistofidis, Robert A. Redd, Michele Moschetta, Salomon Manier, Aldo M. Roccaro, Antonio Sacco, Yu-Tzu Tai, Francois Mercier, Yawara Kawano, Nang Kham Su, Brianna Berrios, John G. Doench, David E. Root, Franziska Michor, David T. Scadden, Irene M. Ghobrial

Blood (2021) 137 (17): 2360–2372.

https://doi.org/10.1182/blood.2020005885

Published: 2021

Includes: Supplemental data

Journal Articles

Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study

Rhonda E. Ries, MA, Amanda R. Leonti, MS, Timothy Junius Triche, Jr., PhD, Robert B. Gerbing, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Jenny L. Smith, MSc, MD, Todd M Cooper, DO, Jason E. Farrar, MD, Aniruddha J. Deshpande, E. Anders Kolb, MD, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 461.

https://doi.org/10.1182/blood-2019-125943

Published: 2019

Journal Articles

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Alison R. Moliterno, MD, Donna Marie Williams, PhD, Liping Li, MD PhD, Lingling Xian, MD PhD, Li Luo, PhD, Amy S. Duffield, MD PhD, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 472.

https://doi.org/10.1182/blood-2019-131432

Published: 2019

Journal Articles

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Monica S. Nair, Johannes M. Waldschmidt, MD, Julia Frede, PhD MPhil, Tushara Vijaykumar, Amy Guillaumet-Adkins, PhD, Valeriya Dimitrova, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD

Blood (2019) 134 (Supplement_1): 1777.

https://doi.org/10.1182/blood-2019-127495

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Liping Li, MD PhD, Wenyan Lu, PhD, Alison R. Moliterno, MD, Lingling Xian, MD PhD, Joseph Kim, BS, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 1680.

https://doi.org/10.1182/blood-2019-130262

Published: 2019

Journal Articles

A FULLY Human Bispecific Antibody Functionally Rescues Factor VIII Deficiency EX VIVO

Wei Wang, PhD, John Blackwood, PhD, Roberto Magliozzi, PhD, Leonardo Moraes, PhD, Jeffrey Hollins, PhD, Alessandro Sinopoli, PhD, Bertie Chi, PhD, Laura Mitchell, PhD, Chris Sellick, PhD, Claire Pearce, PhD, Igor Theurl, MD PhD, Volker Germaschewski, Jacob Galson, PhD, Luca Badiali, PhD, Karen Dickson, PhD, Allan Bradley, PhD, E-Chiang Lee, PhD

Blood (2019) 134 (Supplement_1): 2410.

https://doi.org/10.1182/blood-2019-123359

Published: 2019

Journal Articles

A Novel Sandwich ELISA to Quantify Erythroferrone in Mouse Serum

Patrick Gutschow, MS, Huiling Han, MD, Gordana Olbina, PhD, Keith Westerman, BS, Eileen Westerman, BS, Marc Ruiz Martinez, PhD, Yelena Ginzburg, MD, Elizabeta Nemeth, PhD, Tomas Ganz, MD PhD, Vaughn Ostland, PhD

Blood (2019) 134 (Supplement_1): 2237.

https://doi.org/10.1182/blood-2019-130947

Published: 2019

Journal Articles

Anti-Tumor Effect of the EZH1/2 Dual Inhibitor Valemetostat Against Diffuse Large B-Cell Lymphoma Via Modulation of B-Cell Receptor Signaling and c-Myc Signaling Pathways

Yasuhiro Hama, PhD, Toshihiro Banjo, PhD, Daisuke Honma, PhD, Yoshimi Takata, Emi Nosaka, Machiko Shiroishi, Kenji Watanabe, Yuka Yamamoto, Tsuyoshi Hirata, Rika Nakano, Koichiro Inaki, PhD, Hiroki Goto, PhD, Yusuke Totoki, PhD, Miki Kataoka, Kyungtaek Lim, PhD, Chisa Wada, Eiji Kumazawa, PhD, Shinji Tsutsumi, PhD

Blood (2019) 134 (Supplement_1): 4642.

https://doi.org/10.1182/blood-2019-125436

Published: 2019

Journal Articles

Bioavailable Dual-Protein Degraders of CK1α and Transcriptional Kinase CDK9 As Potential Therapeutics for Hematological Malignancies

Leah Fung, PhD, Aparajita Hoskote Chourasia, PhD, Eduardo Torres, MSc, Imelda Lam, BSc, Paul Erdman, MSc, David Hecht, PhD, Robert Sullivan, PhD, Brooke McElwee, BSc, Normand Richard, MSc, Avanthika Venkatachalam, MSc, Irit Snir-Alkalay, PhD, Kyle WH Chan, PhD, Frank Mercurio, PhD, Yinon Ben-Neriah, MD PhD, David I Stirling, PhD

Blood (2019) 134 (Supplement_1): 4643.

https://doi.org/10.1182/blood-2019-131834

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

Liping Li, MD PhD, Katharina Hayer, Lingling Xian, MD PhD, Li Luo, PhD, Leslie Cope, Andrei Thomas-Tikhonenko, PhD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 3946.

https://doi.org/10.1182/blood-2019-130261

Published: 2019

Journal Articles

R-Loops-Induced ATR Signaling As a Potential Therapeutic Target in Myelodysplastic Syndrome

Johann-Christoph Jann, Johanna Flach, PhD, Antje Knaflic, Eva Altrock, PhD, Nanni Schmitt, MSc, Alexander Streuer, Justine Danner, Franziska Hofmann, Verena Nowak, Nina Draeger, Julia Obländer, Iris Palme, Patrick Wuchter, MD, Ahmed Jawhar, MD, Georgia Metzgeroth, MD, Florian Nolte, MD, Wolf-Karsten Hofmann, MD PhD, Daniel Nowak, MD

Blood (2019) 134 (Supplement_1): 4218.

https://doi.org/10.1182/blood-2019-126431

Published: 2019

Journal Articles

The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses

Zhenzhen Zhao, Yi Wu, Junsong Zhou, Fengwu Chen, Aizhen Yang, David W. Essex

Blood (2019) 133 (3): 246–251.

https://doi.org/10.1182/blood-2018-04-844480

Published: 2019

Includes: Supplemental data

Journal Articles

Donor IFNL4 Genotype Is Associated with Transplant-Related Mortality after Unrelated Donor Myeloablative Hematopoietic Cell Transplantation in Patients with Acute Leukemia

Shahinaz M Gadalla, MDPhD, Tao Wang, BS, Olusegun Onabajo, PhD, Youjin Wang, Michael D. Haagenson, MS, Jennifer A. Sees, MPH, Stephen R. Spellman, Hormuzd A. Katki, PhD, Stephanie J. Lee, MD MPH, Ludmila Prokunina-Olsson, PhD

Blood (2018) 132 (Supplement 1): 968.

https://doi.org/10.1182/blood-2018-99-111391

Published: 2018

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Wenyan Lu, PhD, Briyana Chisholm, BS, Li Luo, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 102.

https://doi.org/10.1182/blood-2018-99-119549

Published: 2018

Journal Articles

Evidence for Epitope-Specific T Cell Responses in HIV-Associated Non Neoplastic Lymphadenopathy: High-Throughput Immunogenetic Evidence

Katerina Gemenetzi, Evangelia Stalika, Andreas Agathangelidis, PhD, Fotis Psomopoulos, Elisavet Vlachonikola, Chrysi Galigalidou, Symeon Metallidis, Triantafylia Koletsa, Kostas Stamatopoulos, MD PhD, Maria Papaioannou, Anastasia Hadzidimitriou, PhD

Blood (2018) 132 (Supplement 1): 1117.

https://doi.org/10.1182/blood-2018-99-118975

Published: 2018

Journal Articles

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Blood (2018) 132 (Supplement 1): 55.

https://doi.org/10.1182/blood-2018-99-113916

Published: 2018

Journal Articles

Targeting CD47 and TNFAIP8 By Mir-155 Overcomes Drug Resistance and Inhibits Tumor Growth through Induction of Phagocytosis and Apoptosis in Multiple Myeloma

Nasrin Rastgoo, PhD, Jahangir Abdi, PhD, Maryam Pourabdollah, MD, Hong Chang, MD

Blood (2018) 132 (Supplement 1): 1923.

https://doi.org/10.1182/blood-2018-99-113057

Published: 2018

Journal Articles

LMO2 Facilitates Synthetic Lethality after PARP Inhibition (PARPi) in Diffuse Large B-Cell Lymphoma (DLBCL)

Ramiro E Verdun, PhD, Salma Parvin, PhD, Ariel Ramirez Labrada, PhD, Gabriel Emmanuel Santiago, Cortizas M Elena, Sharabi Eden, Aumann Shlomzion, MD, Zhang Yu, PhD, Isidro Sanchez-Garcia, PhD, Francisco Vega, MD PhD, Jennifer Rose Chapman-Fredricks, MD, Izidore S. Lossos, MD

Blood (2018) 132 (Supplement 1): 674.

https://doi.org/10.1182/blood-2018-99-110825

Published: 2018

Journal Articles

A Phase 1 Dose Escalation Study of ARQ 531 in Selected Patients with Relapsed or Refractory Hematologic Malignancies

Jennifer A. Woyach, MD, Ian W. Flinn, MD PhD, Deborah M. Stephens, Farrukh T. Awan, MD MS, Kerry A. Rogers, MD, Sean D. Reiff, Ron E. Savage, Sudharshan Eathiraj, Lyndsey A. Szuszkiewicz, Kate Tith, John C. Byrd, MD

Blood (2018) 132 (Supplement 1): 3136.

https://doi.org/10.1182/blood-2018-99-116338

Published: 2018

Journal Articles

Combination Treatment with an MDM2 Antagonist and a BET Inhibitor Targets Both Myelofibrosis Hematopoietic Stem/ Progenitor Cells and Their Tumor Promoting Microenvironment

Min Lu, PhDMD, Lijuan Xia, Mohamed E. Salama, MD, Ronald Hoffman, MD

Blood (2017) 130 (Supplement 1): 4225.

https://doi.org/10.1182/blood.V130.Suppl_1.4225.4225

Published: 2017

NARROW

Progression signature underlies clonal evolution and dissemination of multiple myeloma

Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

A FULLY Human Bispecific Antibody Functionally Rescues Factor VIII Deficiency EX VIVO

A Novel Sandwich ELISA to Quantify Erythroferrone in Mouse Serum

Anti-Tumor Effect of the EZH1/2 Dual Inhibitor Valemetostat Against Diffuse Large B-Cell Lymphoma Via Modulation of B-Cell Receptor Signaling and c-Myc Signaling Pathways

Bioavailable Dual-Protein Degraders of CK1α and Transcriptional Kinase CDK9 As Potential Therapeutics for Hematological Malignancies

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

R-Loops-Induced ATR Signaling As a Potential Therapeutic Target in Myelodysplastic Syndrome

The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses

Donor IFNL4 Genotype Is Associated with Transplant-Related Mortality after Unrelated Donor Myeloablative Hematopoietic Cell Transplantation in Patients with Acute Leukemia

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Evidence for Epitope-Specific T Cell Responses in HIV-Associated Non Neoplastic Lymphadenopathy: High-Throughput Immunogenetic Evidence

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Targeting CD47 and TNFAIP8 By Mir-155 Overcomes Drug Resistance and Inhibits Tumor Growth through Induction of Phagocytosis and Apoptosis in Multiple Myeloma

LMO2 Facilitates Synthetic Lethality after PARP Inhibition (PARPi) in Diffuse Large B-Cell Lymphoma (DLBCL)

A Phase 1 Dose Escalation Study of ARQ 531 in Selected Patients with Relapsed or Refractory Hematologic Malignancies

Combination Treatment with an MDM2 Antagonist and a BET Inhibitor Targets Both Myelofibrosis Hematopoietic Stem/ Progenitor Cells and Their Tumor Promoting Microenvironment

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American Society of Hematology

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ASH Publications

American Society of Hematology

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