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Journal Articles

Single Cell Transcriptome in Chronic Myeloid Leukemia (CML): Pseudotime Analysis Reveals a Rare Population with Embryonic Stem Cell Features and Druggable Intricated Transitional Stem Cell States

Sarah Pagliaro, Pharm D, Christophe Desterke, Herve Acloque, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2018) 132 (Supplement 1): 934.

https://doi.org/10.1182/blood-2018-99-110679

Published: 2018

Journal Articles

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS)

Blood (2017) 130 (Supplement 1): 4277.

https://doi.org/10.1182/blood.V130.Suppl_1.4277.4277

Published: 2017

Journal Articles

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with AML and MDS

Leylah Drusbosky, PhD, Elizabeth Wise, BS, Shireen Vali, PhD, Taher Abbasi, Ansu Kumar, Neeraj Kumar Singh, Kabya Basu, Chandan Kumar, Amjad Husain, Fei Zou, PhD, Caitlin Tucker, BS, Randy A Brown, MD, Maxim Norkin, MD PhD, John Hiemenz, MD, John R. Wingard, MD, Jack W Hsu, MD, Christopher R. Cogle, MD

Blood (2016) 128 (22): 594.

https://doi.org/10.1182/blood.V128.22.594.594

Published: 2016

Journal Articles

Use of 2HG Levels in the Serum, Urine, or Bone Marrow to Predict IDH Mutations in Adults with Acute Myeloid Leukemia

Andrew M. Brunner, MD, Donna S Neuberg, ScD, Seth A. Wander, MD PhD, Hossein Sadrzadeh, MD, Karen K. Ballen, MD, Philip C. Amrein, MD, Gabriela S. Hobbs, MD, Yi-Bin Chen, MD, Ashley M. Perry, BS, Christelle Joseph, Meghan E. Burke, Aura Y Ramos, Regina Silver, Ilene Galinsky, ANP, Sophia Adamia, PhD, Darrell Borger, PhD, Anthony J Iafrate, MD PhD, Richard M. Stone, MD, Amir T. Fathi, MD

Blood (2015) 126 (23): 2597.

https://doi.org/10.1182/blood.V126.23.2597.2597

Published: 2015

Journal Articles

A Comparative Oncology Analysis of Canine T-Cell Lymphoma (TCL): Immunohistochemical Study and Next Generation Sequencing for Protein Analysis and Genomic Target Discovery

Athena Kritharis, MD, J. Tyson McDonald, PhD, Afshin Beheshti, PhD, Monika Pilichowska, MD, Kristine Burgess, DVM, MS, Luisel Ricks-Santi, PhD, Elizabeth McNiel, DVM, PhD, Ravi Dashnamoorthy, PhD, Andrew M. Evens, DO, MSc

Blood (2015) 126 (23): 3883.

https://doi.org/10.1182/blood.V126.23.3883.3883

Published: 2015

Journal Articles

Common cancer-associated PIK3CA activating mutations rarely occur in Langerhans cell histiocytosis

Sébastien Héritier, Raphael Saffroy, Nina Radosevic-Robin, Yolaine Pothin, Héléne Pacquement, Michel Peuchmaur, Antoinette Lemoine, Julien Haroche, Jean Donadieu, Jean-Francois Emile

Blood (2015) 125 (15): 2448–2449.

https://doi.org/10.1182/blood-2015-01-625491

Published: 2015

Includes: Supplemental data

Journal Articles

Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease

Blood (2014) 124 (19): 3016–3019.

https://doi.org/10.1182/blood-2014-04-570937

Published: 2014

Includes: Supplemental data

Journal Articles

The Impact Of Subclonal Versus Clonal Novel Recurrent Mutations On Treatment Outcome In Previously Untreated High Risk CLL Patients: Results From The HOVON68 Trial

Doreen te Raa, MD, Arnon P. Kater, MD PhD, Wendim Ghidey Alemayehu, Alexander Jethwa, Jennifer Hullein, Eric Eldering, PhD, Tatjana Stankovic, MD, PhD, Thorsten Zenz, MD, Christian H Geisler, Marinus H.J. Van Oers, MD, PhD

Blood (2013) 122 (21): 2861.

https://doi.org/10.1182/blood.V122.21.2861.2861

Published: 2013

Journal Articles

P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse

Sunil Iyengar, Andrew Clear, Csaba Bödör, Lenushka Maharaj, Abigail Lee, Maria Calaminici, Janet Matthews, Sameena Iqbal, Rebecca Auer, John Gribben, Simon Joel

Blood (2013) 121 (12): 2274–2284.

https://doi.org/10.1182/blood-2012-10-460832

Published: 2013

Journal Articles

High Resolution Genomic Analysis In CLL Demonstrates Genomic Stability In Untreated Patients and Novel Markers of Progression In Treated Patients

Jennifer R Brown, MD, PhD, Megan Hanna, Bethany Tesar, Lillian Werner, Hazel Reynolds, Stacey M Fernandes, Laura Macconaill, Yaoyu Wang, Mick Correll, Donna Neuberg, ScD, Arnold S. Freedman, MD

Blood (2010) 116 (21): 2426.

https://doi.org/10.1182/blood.V116.21.2426.2426

Published: 2010

Journal Articles

SHIP1 and PTEN Co-Inactivation and Akt Pathway Targeting in ALL.

Mitchell B. Diccianni, PhD, BSc, Lisa M. Barnhill, BS, Tony Lo, BS, MS, Alice L. Yu, PhD

Blood (2009) 114 (22): 2386.

https://doi.org/10.1182/blood.V114.22.2386.2386

Published: 2009

Journal Articles

Mutations in the Catalytic Subunit of Class IA PI3K Are Leukemogenic In Vivo.

Stefan Horn, James A. McCubrey, Carol Stocking, Lorenz Trumper, Jorg Basecke

Blood (2007) 110 (11): 875.

https://doi.org/10.1182/blood.V110.11.875.875

Published: 2007

Journal Articles

Mutations of the Catalytic Subunit of Class IA PI3K Are Constitutively Active and Confer Factor-Independent Growth to Early Hematopoietic Cells.

Stefan Horn, James McCubrey, Carol Stocking, Lorenz Truemper, Jorg Basecke

Blood (2006) 108 (11): 1455.

https://doi.org/10.1182/blood.V108.11.1455.1455

Published: 2006

Journal Articles

Frequent Mutation of the PIK3CA Gene in Saudi Arabian Diffuse Large B-Cell Lymphoma.

Jehad A. Abubaker, PhD, Prashant P. Bavi, MD, Sayer Al-Harbi, MSc, Valerie L. Atizado, Bsc, Fouad Al-Dayel, MD, Adnan Ezzat, MD, Shahab Uddin, PhD, Khawla S. Al-Kuraya, MD, FCAP

Blood (2006) 108 (11): 4308.

https://doi.org/10.1182/blood.V108.11.4308.4308

Published: 2006

Journal Articles

Rare Mutations of the PIK3CA Gene in Hematologic Malignancies.

Claudia I. Muller, M.D., Carl W. Miller, Ph.D., Wolf-K. Hofmann, M.D., Norihiko Kawamata, M.D., Ph.D., H. Phillip Koeffler, M.D.

Blood (2004) 104 (11): 4350.

https://doi.org/10.1182/blood.V104.11.4350.4350

Published: 2004

Journal Articles

Mutations of Oncogenes Involved in Signal Transduction Pathways Are Common in AML.

Michael C. Heinrich, M.D., Andrea Haley, Patina Harell, Ajia Town, Troy Bainbridge, Marcus Schittenhelm, M.D., Laura McGreevey, Rita Braziel, M.D.

Blood (2004) 104 (11): 2575.

https://doi.org/10.1182/blood.V104.11.2575.2575

Published: 2004

NARROW

Single Cell Transcriptome in Chronic Myeloid Leukemia (CML): Pseudotime Analysis Reveals a Rare Population with Embryonic Stem Cell Features and Druggable Intricated Transitional Stem Cell States

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS)

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with AML and MDS

Use of 2HG Levels in the Serum, Urine, or Bone Marrow to Predict IDH Mutations in Adults with Acute Myeloid Leukemia

A Comparative Oncology Analysis of Canine T-Cell Lymphoma (TCL): Immunohistochemical Study and Next Generation Sequencing for Protein Analysis and Genomic Target Discovery

Common cancer-associated PIK3CA activating mutations rarely occur in Langerhans cell histiocytosis

Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease

The Impact Of Subclonal Versus Clonal Novel Recurrent Mutations On Treatment Outcome In Previously Untreated High Risk CLL Patients: Results From The HOVON68 Trial

P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse

High Resolution Genomic Analysis In CLL Demonstrates Genomic Stability In Untreated Patients and Novel Markers of Progression In Treated Patients

SHIP1 and PTEN Co-Inactivation and Akt Pathway Targeting in ALL.

Mutations in the Catalytic Subunit of Class IA PI3K Are Leukemogenic In Vivo.

Mutations of the Catalytic Subunit of Class IA PI3K Are Constitutively Active and Confer Factor-Independent Growth to Early Hematopoietic Cells.

Frequent Mutation of the PIK3CA Gene in Saudi Arabian Diffuse Large B-Cell Lymphoma.

Rare Mutations of the PIK3CA Gene in Hematologic Malignancies.

Mutations of Oncogenes Involved in Signal Transduction Pathways Are Common in AML.

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American Society of Hematology

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American Society of Hematology

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