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Chandan Kumar
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Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM)-Based Assessment of Cytarabine (ARA-C) and Anthracycline Response and Novel Biomarker Response Criteria for the Addition of Etoposide (VP16) in Acute Myeloid Leukemia (AML)

Michael Castro, Scott C Howard, Ansu Kumar, Vivek Patil, Swati Khandelwal, Drew Watson, Shweta Kapoor, Pallavi Kumari, Samiksha Avinash Prasad, Neha Gupta, Neelesh Lunkad, Upasana Mitra, Poornachandra G, Chandan Kumar, Sayantani Roy Choudhury, Shruthi Kulkarni, Ashish Choudhary, Annapoorna Prakash, Zakir Husain, Adity Ghosh, Yugandhara Narvekar, Anish Raju R Amara, Velkuru Yuvavani, Sanjana Patel, Michele Dundas Macpherson, Guido Marcucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 1299.
https://doi.org/10.1182/blood-2021-152745
Published: 2021
Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Genomic and Molecular Markers for Decitabine (DAC) Plus Valproic-Acid (VPA) Treatment Response in Patients with Myelodysplastic Syndromes (MDS)

Michael Castro, Ansu Kumar, Himanshu Grover, Vivek Patil, Shweta Kapoor, Ashish Kumar Agrawal, Mohammed Sauban, Samiksha Avinash Prasad, Kabya Basu, Rakhi Purushothaman Suseela, Chandan Kumar, Prashant Ramachandran Nair, Pallavi Kumari, Anusha Pampana, Yashaswini S Ullal, Humera Azam, Nagendra Prasad, Anish Raju R Amara, Diwyanshu Sahu, Nithya T Raveendaran, Archana Palillam Veedu, Nirjhar Mundkur, Sanjana Patel, James Christie, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 2615.
https://doi.org/10.1182/blood-2021-153220
Published: 2021
Journal Articles

Monosomy 7 and Co-Occurrent Genomic Aberrations Determine Chemotherapy Response in Acute Myeloid Leukemia (AML) Patients Using the Cellworks Omics Biology Model (CBM): Mycare-021-04

Michael Castro, MD, Drew Watson, PhD, Ansu Kumar, M.Sc., Prashant Ramachandran Nair, B.Tech., Himanshu Grover, M.S., Diwyanshu Sahu, M.Sc., Subrat Mohapatra, M.Sc., Poornachandra G, B.Tech., Ashish Agarwal, B.V.Sc., Rakhi Purushothaman Suseela, B.Tech., Naga Ganesh, B.Tech., Mohammed Sauban, B.E., Chandan Kumar, M.Tech., Rahul K Raman, M.Sc., Divya Singh, M.S., Sayani Basu, M.Tech., Neelesh Lunkad, M.Tech., Nirjhar Mundkur, B.S., Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc., Scott Howard, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9.
https://doi.org/10.1182/blood-2020-140087
Published: 2020
Journal Articles

Mechanisms of Azacitidine Chemotherapy Resistance in AML and MDS and New Therapy Options

Lubomir Minarik, MD, Leylah M. Drusbosky, PhD, Taher Abbasi, MS, MBA, Karina Vargova, MBBS, MSc, Vojtech Kulvait, PhD, Anna Jonasova, MD, Neeraj Kumar Singh, B.Tech, Chandan Kumar, M.Tech, Rakhi Purushothaman Suseela, B.Tech, Mamatha Patil, B.E, Patil Nilesh Dattatraya, M.Sc., Krishna Kumar Tiwari, B.Tech, Shireen Vali, PhD, Christopher R. Cogle, MD, Tomas Stopka, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5506.
https://doi.org/10.1182/blood-2018-99-114466
Published: 2018
Journal Articles

A Genomic Signature Predicting Venetoclax Treatment Response in Acute Myeloid Leukemia (AML) Identified By Protein Network Mapping and Validated By Ex Vivo Ddrug Sensitivity Testing

Leylah M. Drusbosky, PhD, Kimberly E. Hawkins, PhD BS, Helen L. Leather, Hemant S. Murthy, MD, Nosha Farhadfar, MD, John R. Wingard, MD, Maxim Norkin, MD, Randy A. Brown, MD, John W. Hiemenz, MD, Paul Castillo, MD, Biljana N. Horn, MD, Ansu Kumar, MS, Neeraj Kumar Singh, B.Tech, Chandan Kumar, MT, Sumanth Vasista, BE, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Cristina E. Tognon, PhD, Stephen E Kurtz, PhD, Brian J. Druker, MD, Jeffrey W. Tyner, PhD, Daniel A. Pollyea, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2707.
https://doi.org/10.1182/blood.V130.Suppl_1.2707.2707
Published: 2017
Journal Articles

Computational Biology Approach to Predict Hypomethylating Agent (HMA) Response Using Genomic and Clinical Characteristics in Myelodsyplastic Syndromes (MDS)

Leylah M. Drusbosky, PhD, Salah-Eddin Komrokji, Najla Al Ali, M.Sc, Neeraj Kumar Singh, B.Tech, Chandan Kumar, MT, Sumanth Vasista, BE, Diwyanshu Sahu, M.Sc., Ganesh Naga, BT, Patil Dattatraya, MS, Taher Abbasi, MS, MBA, Shireen Vali, PhD, David A Sallman, MD, Rami S. Komrokji, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2954.
https://doi.org/10.1182/blood.V130.Suppl_1.2954.2954
Published: 2017
Journal Articles

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with AML and MDS

Leylah Drusbosky, PhD, Elizabeth Wise, BS, Shireen Vali, PhD, Taher Abbasi, Ansu Kumar, Neeraj Kumar Singh, Kabya Basu, Chandan Kumar, Amjad Husain, Fei Zou, PhD, Caitlin Tucker, BS, Randy A Brown, MD, Maxim Norkin, MD PhD, John Hiemenz, MD, John R. Wingard, MD, Jack W Hsu, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2016) 128 (22): 594.
https://doi.org/10.1182/blood.V128.22.594.594
Published: 2016