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Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Genomic and Molecular Markers for Decitabine (DAC) Plus Valproic-Acid (VPA) Treatment Response in Patients with Myelodysplastic Syndromes (MDS)

Michael Castro, Ansu Kumar, Himanshu Grover, Vivek Patil, Shweta Kapoor, Ashish Kumar Agrawal, Mohammed Sauban, Samiksha Avinash Prasad, Kabya Basu, Rakhi Purushothaman Suseela, Chandan Kumar, Prashant Ramachandran Nair, Pallavi Kumari, Anusha Pampana, Yashaswini S Ullal, Humera Azam, Nagendra Prasad, Anish Raju R Amara, Diwyanshu Sahu, Nithya T Raveendaran, Archana Palillam Veedu, Nirjhar Mundkur, Sanjana Patel, James Christie, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 2615.
https://doi.org/10.1182/blood-2021-153220
Published: 2021
Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Novel Biomarkers to Inform Mitoxantrone, Etoposide, and Cytarabine (MEC)-Based Combination Therapy in Refractory & Relapsed Acute Myeloid Leukemia (AML) Patients

Guido Marcucci, Ansu Kumar, Michael Castro, Himanshu Grover, Vivek Patil, Aftab Alam, Humera Azam, Subrat Mohapatra, Anuj Tyagi, Pallavi Kumari, Samiksha Avinash Prasad, Prashant Ramachandran Nair, Neelesh Lunkad, Vishwas Joseph, Poornachandra G, Jyoti Chauhan, Sayani Basu, Liptimayee Behura, Adity Ghosh, Zakir Husain, Rema Mandal, Rahul K Raman, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 4453.
https://doi.org/10.1182/blood-2021-153769
Published: 2021
Journal Articles

Predicting Resistance to the Combination of ATO and ATRA in APL Patients with PML-Rara Fusions, Using a Computational Biology Modeling Approach: Mycare-021-01

Scott Howard, MD, Prashant Ramachandran Nair, B.Tech., Himanshu Grover, M.S., Anuj Tyagi, M.Sc., Pallavi Kumari, M.Sc., Samiksha Avinash Prasad, M.Sc., Upasana Mitra, M.Sc., Deepak Anil Lala, B.Tech., Humera Azam, M.Sc., Neha Gupta, M.Sc., Subrat Mohapatra, M.Sc., Poornachandra G, B.Tech., Nirjhar Mundkur, Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc.
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-140617
Published: 2020
Journal Articles

Predicting Response to Dasatinib Using a Computational Model and Its Validation: A Beat AML Project Study

Jeffrey W. Tyner, PhD, Brian J. Druker, MD, Cristina E. Tognon, PhD, Stephen E Kurtz, PhD, Leylah M. Drusbosky, PhD, Diwyanshu Sahu, M.Sc., Robinson Vidva, B.Tech, Shweta Kapoor, M.Sc., Humera Azam, M.Sc., Rajeev Kumar, B.Tech, Padmagiri G Chickdipatti, B.E, Nithya T Raveendaran, M.Tech, Reshma P Gopi, M.Sc., Taher Abbasi, MS, MBA, Shireen Vali, PhD, Christopher R. Cogle, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1541.
https://doi.org/10.1182/blood-2018-99-115678
Published: 2018
Journal Articles

Predicting Mechanisms of Ibrutinib-Resistance in Chronic Lymphocytic Leukemia (CLL) Using Computational-Based Modeling for Personalized Therapy with Clinical Validation

Leylah M. Drusbosky, PhD, Aneel Paulus, MD, Anne Quillet Mary, PhD, Loic Ysebaert, MD PhD, Ansu Kumar, MS, Neeraj Kumar Singh, B.Tech, Yashaswini Ullal, BE, Priyanka Bhargav, BE, Humera Azam, MS, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Asher A. Chanan-Khan, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4278.
https://doi.org/10.1182/blood.V130.Suppl_1.4278.4278
Published: 2017