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Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Novel Biomarkers to Inform Mitoxantrone, Etoposide, and Cytarabine (MEC)-Based Combination Therapy in Refractory & Relapsed Acute Myeloid Leukemia (AML) Patients

Guido Marcucci, Ansu Kumar, Michael Castro, Himanshu Grover, Vivek Patil, Aftab Alam, Humera Azam, Subrat Mohapatra, Anuj Tyagi, Pallavi Kumari, Samiksha Avinash Prasad, Prashant Ramachandran Nair, Neelesh Lunkad, Vishwas Joseph, Poornachandra G, Jyoti Chauhan, Sayani Basu, Liptimayee Behura, Adity Ghosh, Zakir Husain, Rema Mandal, Rahul K Raman, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 4453.
https://doi.org/10.1182/blood-2021-153769
Published: 2021
Journal Articles

Therapy Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Is Predictive of Individual Acute Myeloid Leukemia (AML) Patient Probability of Clinical Response (CR) and Overall Survival (OS): Mycare-023

Scott C Howard, Drew Watson, Michael Castro, Shweta Kapoor, Prashant Ramachandran Nair, Samiksha Avinash Prasad, Swaminathan Rajagopalan, Aftab Alam, Kunal Ghosh Roy, Diwyanshu Sahu, Deepak Anil Lala, Kabya Basu, Yashaswini S Ullal, Yugandhara Narvekar, Adity Ghosh, Mohammed Sauban, Poornachandra G, Ashish Kumar Agrawal, Anuj Tyagi, Rakhi Purushothaman Suseela, Karthik Sundara Raju, Anusha Pampana, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Guido Marcucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 689.
https://doi.org/10.1182/blood-2021-154023
Published: 2021
Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Genomic and Molecular Markers for Decitabine (DAC) Plus Valproic-Acid (VPA) Treatment Response in Patients with Myelodysplastic Syndromes (MDS)

Michael Castro, Ansu Kumar, Himanshu Grover, Vivek Patil, Shweta Kapoor, Ashish Kumar Agrawal, Mohammed Sauban, Samiksha Avinash Prasad, Kabya Basu, Rakhi Purushothaman Suseela, Chandan Kumar, Prashant Ramachandran Nair, Pallavi Kumari, Anusha Pampana, Yashaswini S Ullal, Humera Azam, Nagendra Prasad, Anish Raju R Amara, Diwyanshu Sahu, Nithya T Raveendaran, Archana Palillam Veedu, Nirjhar Mundkur, Sanjana Patel, James Christie, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 2615.
https://doi.org/10.1182/blood-2021-153220
Published: 2021
Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Immune Modulation As a Key Pathway for Predicting Azacitidine (AZA) Response in Myelodysplastic Syndromes (MDS)

Scott C Howard, Ansu Kumar, Michael Castro, Himanshu Grover, Subrat Mohapatra, Shweta Kapoor, Anuj Tyagi, Prashant Ramachandran Nair, Rakhi Purushothaman Suseela, Anusha Pampana, Deepak Anil Lala, Divya Singh, Vijayashree P Shyamasundar, Shruthi Kulkarni, Yugandhara Narvekar, Kritika Sahni, Rahul K Raman, Veena Balakrishnan, Mamatha Patil, Naga Ganesh Palaniyeppa, Ashokraja Balla, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Guido Marcucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 3690.
https://doi.org/10.1182/blood-2021-153539
Published: 2021
Journal Articles

Superior Therapy Response Predictions for Patients with Myelodysplastic Syndrome (MDS) Using Cellworks Singula™: Mycare-020-02

Anthony S. Stein, MD, Drew Watson, PhD, Prashant Ramachandran Nair, B.Tech., Kabya Basu, M.Sc., Yashaswini S Ullal, M.Tech., Adity Ghosh, M.Sc., Yugandhara Narvekar, M.Sc., Himanshu Grover, M.S., Diwyanshu Sahu, M.Sc., Annapoorna Prakash, M.Tech., Liptimayee Behura, B.E., Veena Balakrishnan, M.Sc., Kunal Ghosh Roy, M.Sc., Swaminathan Rajagopalan, M.Tech., Aftab Alam, M.Sc., Rajan Parashar, B.Tech., Nirjhar Mundkur, James Christie, B.S., Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc., Guido Marcucci, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-142214
Published: 2020
Journal Articles

Assessment of Cellworks Omics Biosimulation Therapy Response Predictions for Patients with Acute Myeloid Leukemia (AML) Using Cellworks Singula™: Mycare-020-01

Guido Marcucci, MD, Drew Watson, PhD, Prashant Ramachandran Nair, B.Tech., Kabya Basu, M.Sc., Yashaswini S Ullal, M.Tech., Adity Ghosh, M.Sc., Yugandhara Narvekar, M.Sc., Himanshu Grover, M.S., Diwyanshu Sahu, M.Sc., Anish Raju R Amara, B.E., Anusha Pampana, M.Sc., Kunal Ghosh Roy, M.Sc., Swaminathan Rajagopalan, M.Tech., Aftab Alam, M.Sc., Rajan Parashar, B.Tech., Nirjhar Mundkur, James Christie, B.S., Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc., Anthony S. Stein, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-142184
Published: 2020