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Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Novel Biomarkers to Inform Mitoxantrone, Etoposide, and Cytarabine (MEC)-Based Combination Therapy in Refractory & Relapsed Acute Myeloid Leukemia (AML) Patients

Guido Marcucci, Ansu Kumar, Michael Castro, Himanshu Grover, Vivek Patil, Aftab Alam, Humera Azam, Subrat Mohapatra, Anuj Tyagi, Pallavi Kumari, Samiksha Avinash Prasad, Prashant Ramachandran Nair, Neelesh Lunkad, Vishwas Joseph, Poornachandra G, Jyoti Chauhan, Sayani Basu, Liptimayee Behura, Adity Ghosh, Zakir Husain, Rema Mandal, Rahul K Raman, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 4453.
https://doi.org/10.1182/blood-2021-153769
Published: 2021
Journal Articles

Therapy Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Is Predictive of Individual Acute Myeloid Leukemia (AML) Patient Probability of Clinical Response (CR) and Overall Survival (OS): Mycare-023

Scott C Howard, Drew Watson, Michael Castro, Shweta Kapoor, Prashant Ramachandran Nair, Samiksha Avinash Prasad, Swaminathan Rajagopalan, Aftab Alam, Kunal Ghosh Roy, Diwyanshu Sahu, Deepak Anil Lala, Kabya Basu, Yashaswini S Ullal, Yugandhara Narvekar, Adity Ghosh, Mohammed Sauban, Poornachandra G, Ashish Kumar Agrawal, Anuj Tyagi, Rakhi Purushothaman Suseela, Karthik Sundara Raju, Anusha Pampana, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Guido Marcucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 689.
https://doi.org/10.1182/blood-2021-154023
Published: 2021
Journal Articles

Superior Therapy Response Predictions for Patients with Myelodysplastic Syndrome (MDS) Using Cellworks Singula™: Mycare-020-02

Anthony S. Stein, MD, Drew Watson, PhD, Prashant Ramachandran Nair, B.Tech., Kabya Basu, M.Sc., Yashaswini S Ullal, M.Tech., Adity Ghosh, M.Sc., Yugandhara Narvekar, M.Sc., Himanshu Grover, M.S., Diwyanshu Sahu, M.Sc., Annapoorna Prakash, M.Tech., Liptimayee Behura, B.E., Veena Balakrishnan, M.Sc., Kunal Ghosh Roy, M.Sc., Swaminathan Rajagopalan, M.Tech., Aftab Alam, M.Sc., Rajan Parashar, B.Tech., Nirjhar Mundkur, James Christie, B.S., Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc., Guido Marcucci, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-142214
Published: 2020
Journal Articles

Assessment of Cellworks Omics Biosimulation Therapy Response Predictions for Patients with Acute Myeloid Leukemia (AML) Using Cellworks Singula™: Mycare-020-01

Guido Marcucci, MD, Drew Watson, PhD, Prashant Ramachandran Nair, B.Tech., Kabya Basu, M.Sc., Yashaswini S Ullal, M.Tech., Adity Ghosh, M.Sc., Yugandhara Narvekar, M.Sc., Himanshu Grover, M.S., Diwyanshu Sahu, M.Sc., Anish Raju R Amara, B.E., Anusha Pampana, M.Sc., Kunal Ghosh Roy, M.Sc., Swaminathan Rajagopalan, M.Tech., Aftab Alam, M.Sc., Rajan Parashar, B.Tech., Nirjhar Mundkur, James Christie, B.S., Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc., Anthony S. Stein, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-142184
Published: 2020
Journal Articles

WT1 and BCORL1 Identified By Computational Biology Modeling Analysis of Patient Genomics Are Novel Predictors of Response to Azacitidine (AZA) and Lenalidomide (LEN) Treatment in Acute Myeloid Leukemia (AML)

Brett M Stevens, PhD, Amanda Winters, MDPhD, Taher Abbasi, MS, MBA, Neeraj Kumar Singh, B.Tech, Yashaswini S Ullal, B.E, Ilu Kumari, M.Sc., Anuj Tyagi, M.Sc., Aftab Alam, M.Sc., Neelesh Lunkad, M.Tech, Leylah M. Drusbosky, PhD, Christopher R. Cogle, MD, Shireen Vali, PhD, Daniel A Pollyea, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1538.
https://doi.org/10.1182/blood-2018-99-114429
Published: 2018
Journal Articles

Computational Biology Model of ETP-ALL Used to Accurately Classify ETP-ALL Vs Non ETP-ALL Patients with Genomic Input

Leylah M. Drusbosky, PhD, Ansu Kumar, MS, Shwetha K, BE, Sumanth Vasista, BE, Anuj Tyagi, MS, Swaminathan Rajagopalan, MT, Aftab Alam, MS, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Girish Chinnaswamy, MD MRCP, Manju Sengar, MD DM, Bijal D. Shah, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1449.
https://doi.org/10.1182/blood.V130.Suppl_1.1449.1449
Published: 2017
Journal Articles

Ex Vivo Patient-Specific Validation Of Personalized Therapeutic Designed For Multiple Myeloma

Nicole A Doudican, PhD, Shireen Vali, PhD, Shweta Kapoor, Anay Talawdekar, Zeba Sultana, Aftab Alam, Ansu Kumar, Neeraj Kumar Singh, Anuj Tyagi, Taher Abbasi, Amitabha Mazumder, M.D.
Journal: Blood
Blood (2013) 122 (21): 4219.
https://doi.org/10.1182/blood.V122.21.4219.4219
Published: 2013
Journal Articles

Predictive Simulation Based Design and Validation Of Repurposed Novel Therapeutics With Multi-Target Mechanisms For Multiple Myeloma

Nicole A Doudican, PhD, Shireen Vali, PhD, Shweta Kapoor, Anay Talawdekar, Zeba Sultana, Aftab Alam, Taher Abbasi, Amitabha Mazumder, M.D.
Journal: Blood
Blood (2013) 122 (21): 3859.
https://doi.org/10.1182/blood.V122.21.3859.3859
Published: 2013