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Journal Articles

Towards Safer Allogeneic HSCT in Autoimmunity: Proof of Concept in Diabetes-Prone Mice

Rakefet Sidlik Muskatel, MD, Bar Nathansohn-Levi, PhD, Esther BACHAR Lustig, PhD, Yair Reisner, PhD

Blood (2019) 134 (Supplement_1): 3212.

https://doi.org/10.1182/blood-2019-124905

Published: 2019

Journal Articles

Pharmacokinetics and Biodistribution of Locked Nucleic Acid (LNA)-Mir-221 Inhibitor: A New Promising Anti-Myeloma Agent

Maria Eugenia Gallo Cantafio, PhD, Annamaria Gulla, MD, Nicola Amodio, PhD, Emanuela Leone, PhD, Eugenio Morelli, MD, Lavinia Biamonte, PhD, Antonino Neri, Pr, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD, Maria Teresa Di Martino

Blood (2015) 126 (23): 3025.

https://doi.org/10.1182/blood.V126.23.3025.3025

Published: 2015

Journal Articles

Longterm Multilineage Human Hematopoietic Repopulation of Untreated KIT-Mutant Immunodeficient Mice

Paul H. Miller, Gabrielle Rabu, David J.H.F. Knapp, Alice M.S. Cheung, PhD, Kiran Dhillon, Philip A. Beer, MRCP, FRCPath, PhD, Connie J. Eaves, PhD

Blood (2014) 124 (21): 2415.

https://doi.org/10.1182/blood.V124.21.2415.2415

Published: 2014

Journal Articles

Blockade Of CD47 Using SIRPαFc: Role Of The Fc Region In Anti-Leukemic Activity and Tolerability

Robert A. Uger, PhD, Xinli Pang, MD, PhD, Mark Wong, PhD, Violetta House, Karen Dodge, Stephane Viau, Noel T. Vigo, Debbie Tam, Tran Truong, Liqing Jin, MD, Andrei V. Malko, Jenny Ho, MD, Tatiana K. Prasolava, PhD, Jayne S. Danska, PhD, Jean C.Y. Wang, MD PhD, Penka S. Petrova, PhD

Blood (2013) 122 (21): 3935.

https://doi.org/10.1182/blood.V122.21.3935.3935

Published: 2013

Journal Articles

In Vitro and Vivo Activity Against Multiple Myeloma Cells Of a Novel Locked Nucleic Acid (LNA)-Mir-221 Inhibitor

Maria Teresa Di Martino, PhD, Annamaria Gullà, MD, Maria Eugenia Gallo Cantafio, Emanuela Altomare, PhD, Nicola Amodio, PhD, Emanuela Leone, PhD, Santo Giovanni Lio, Eugenio Morelli, MD, Daniele Caracciolo, MD, Cirino Botta, MD, Antonino Neri, MD, Niels M Frandsen, PhD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2013) 122 (21): 3166.

https://doi.org/10.1182/blood.V122.21.3166.3166

Published: 2013

Journal Articles

Evaluation Of Targeting CD47-SIRPα Using Primary Effusion Lymphoma Xenograft Mouse Model

Hiroki Goto, MD, Eriko Kudo, Kouki Matsuda, Ryusho Kariya, Manabu Taura, PhD, Seiji Okada, MD, PhD

Blood (2013) 122 (21): 1827.

https://doi.org/10.1182/blood.V122.21.1827.1827

Published: 2013

Journal Articles

BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model

Chika Iwamoto, Katsuto Takenaka, MD, PhD, Shingo Urata, MD, Takahiro Shima, MD, Takuji Yamauchi, MD, PhD, Takuro Kuriyama, MD, PhD, Shinya Daitoku, MD, Yasuyuki Saito, MD, PhD, Katsuhiko Itoh, MD, PhD, Junji Kishimoto, PhD, Daisuke Kohda, PhD, Takashi Matozaki, MD, PhD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 337.

https://doi.org/10.1182/blood.V122.21.337.337

Published: 2013

Journal Articles

Anti-Thymocyte Globulin (ATG) Differentially Depletes naïve and Memory T Cells and Permits Memory-Type Regulatory T Cells

Chang-Qing Xia, Anna Chernatynskaya, Clive Wasserfall, Benjamin Looney, Suigui Wan, Michael Clare-Salzler, Mark Atkinson

Blood (2012) 120 (21): 4670.

https://doi.org/10.1182/blood.V120.21.4670.4670

Published: 2012

Journal Articles

Synergy of Sequential and Concurrent Administration of a Deglycosylated Ricin A Chain-Containing Combined Anti-CD19 and Anti-CD22 Immunotoxin (Combotox) and Cytarabine in a Murine Model of Advanced Acute Lymphoblastic Leukemia

Stefan K Barta, MD, MS, MRCP, Yiyu Zou, PhD, John Schindler, PhD, Tushar Bhagat, Victor Ghetie, PhD, Ellen S Vitetta, MS, PhD, Amit Verma, MD

Blood (2011) 118 (21): 1526.

https://doi.org/10.1182/blood.V118.21.1526.1526

Published: 2011

Journal Articles

Critical Role for DOCK2 in CD8 + /TCR − Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells

Yujie Wen, Mary J Elliott, Yiming Huang, Deborah R Corbin, Yoshinori Fukui, Mariusz Z Ratajczak, Suzanne T Ildstad

Blood (2011) 118 (21): 142.

https://doi.org/10.1182/blood.V118.21.142.142

Published: 2011

Journal Articles

Preclinical Studies of Salinomycin In Multiple Myeloma (MM) Models: Targeting of Side Population (SP) Cells In the Context of Tumor – Microenvironment Interactions.

Efstathios Kastritis, Jana Jakubikova, Jake Delmore, Steffen Klippel, Douglas W. McMillin, Melissa Ooi, Hannah M. Jacobs, Jacob P. Laubach, Paul G Richardson, Kenneth C. Anderson, Andrew L. Kung, Constantine S. Mitsiades, MD, PhD

Blood (2010) 116 (21): 1574.

https://doi.org/10.1182/blood.V116.21.1574.1574

Published: 2010

Journal Articles

Treatment with mTOR Inhibitor, Everolimus (RAD001) Overcomes Resistance to Imatinib In Ph-Leukemia Quiescent Cells.

Yachiyo Kuwatsuka, MD, Yosuke Minami, MD, PhD, Miho Minami, Ryohei Tanizaki, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2010) 116 (21): 1579.

https://doi.org/10.1182/blood.V116.21.1579.1579

Published: 2010

Journal Articles

Methyljasmonate, An Inhibitor of Glycolytic Energy Production, Displays Pre-Clinical Activity against Multiple Myeloma Cells.

Steffen Klippel, Jana Jakubikova, Jake Delmore, Melissa G. Ooi, Douglas McMillin, Efstathios Kastritis, Jacob Laubach, Paul G. Richardson, Kenneth C. Anderson, Constantine S. Mitsiades

Blood (2009) 114 (22): 1741.

https://doi.org/10.1182/blood.V114.22.1741.1741

Published: 2009

Journal Articles

Chimeric Regulatory T cells Enhance HSC Engraftment in An Antigen-Specific Fashion.

Yiming Huang, M.D., Larry D Bozulic, Ph.D, Thomas Miller, B.S., Hong Xu, M.D., Yujie Wen, Ph.D, Lala-Rukh Hussain, B.S., Suzanne T Ildstad, M.D.

Blood (2009) 114 (22): 2424.

https://doi.org/10.1182/blood.V114.22.2424.2424

Published: 2009

Journal Articles

Antitumor Activity of MLN9708, a Second-Generation Proteasome Inhibitor, in Preclinical Models of Lymphoma.

Jill Donelan, Bret Bannerman, Kristen Bano, Trisha Babcock, Paul Hales, Bradley Stringer, Kristine Burke, Hadi Danaee, Laura Faron-Yowe, Erik Koenig, David Lichter, Erik Kupperman

Blood (2009) 114 (22): 3724.

https://doi.org/10.1182/blood.V114.22.3724.3724

Published: 2009

Journal Articles

Pre-Clinical Antitumor activity of MLN4924, An Inhibitor of NEDD8-Activating Enzyme (NAE), in a Novel Primary Human DLBCL Xenograft Model.

Tary Traore, James J. Garnsey, Erik Koenig, Allison J Berger, Mark G Manfredi, PhD, Lilli Petruzzelli, MD, PhD, Peter G. Smith, PhD

Blood (2009) 114 (22): 927.

https://doi.org/10.1182/blood.V114.22.927.927

Published: 2009

Journal Articles

Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development

Armelle Le Campion, Marie-Claude Gagnerault, Cédric Auffray, Chantal Bécourt, Maud Poitrasson-Rivière, Eliette Lallemand, Boris Bienvenu, Bruno Martin, Françoise Lepault, Bruno Lucas

Blood (2009) 114 (9): 1784–1793.

https://doi.org/10.1182/blood-2008-12-192120

Published: 2009

Includes: Supplemental data

Journal Articles

CD8 + /TCR − Facilitating Cells Induce Generation of Regulatory T cells in Vivo: Chimeric Regulatory T Cells are Antigen-Specific and Enhance Engraftment of Allogeneic HSC in Non-Obese Diabetic (NOD) Mice.

Yiming Huang, M.D., Larry D Bozulic, Ph.D, Thomas Miller, B.S., Hong Xu, M.D., Lala-Rukh Hussain, B.S., Suzanne T. Ildstad, MD

Blood (2008) 112 (11): 2318.

https://doi.org/10.1182/blood.V112.11.2318.2318

Published: 2008

Journal Articles

Costimulatory Blockade Enhances Engraftment and Prevents Anti-Donor Antibody Generation in Nonmyeloablative Conditioned Prediabetic NOD Mice

Larry D Bozulic, Ph.D, Hong Xu, M.D., Yiming Huang, M.D., Suzanne T Ildstad, M.D.

Blood (2008) 112 (11): 4597.

https://doi.org/10.1182/blood.V112.11.4597.4597

Published: 2008

Journal Articles

Constitutive expression of IL-12Rβ2 on human multiple myeloma cells delineates a novel therapeutic target

Irma Airoldi, Claudia Cocco, Nicola Giuliani, Marina Ferrarini, Simona Colla, Emanuela Ognio, Giuseppe Taverniti, Emma Di Carlo, Giovanna Cutrona, Vittorio Perfetti, Vittorio Rizzoli, Domenico Ribatti, Vito Pistoia

Blood (2008) 112 (3): 750–759.

https://doi.org/10.1182/blood-2008-02-139378

Published: 2008

NARROW

Towards Safer Allogeneic HSCT in Autoimmunity: Proof of Concept in Diabetes-Prone Mice

Pharmacokinetics and Biodistribution of Locked Nucleic Acid (LNA)-Mir-221 Inhibitor: A New Promising Anti-Myeloma Agent

Longterm Multilineage Human Hematopoietic Repopulation of Untreated KIT-Mutant Immunodeficient Mice

Blockade Of CD47 Using SIRPαFc: Role Of The Fc Region In Anti-Leukemic Activity and Tolerability

In Vitro and Vivo Activity Against Multiple Myeloma Cells Of a Novel Locked Nucleic Acid (LNA)-Mir-221 Inhibitor

Evaluation Of Targeting CD47-SIRPα Using Primary Effusion Lymphoma Xenograft Mouse Model

BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model

Anti-Thymocyte Globulin (ATG) Differentially Depletes naïve and Memory T Cells and Permits Memory-Type Regulatory T Cells

Synergy of Sequential and Concurrent Administration of a Deglycosylated Ricin A Chain-Containing Combined Anti-CD19 and Anti-CD22 Immunotoxin (Combotox) and Cytarabine in a Murine Model of Advanced Acute Lymphoblastic Leukemia

Critical Role for DOCK2 in CD8 + /TCR − Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells

Preclinical Studies of Salinomycin In Multiple Myeloma (MM) Models: Targeting of Side Population (SP) Cells In the Context of Tumor – Microenvironment Interactions.

Treatment with mTOR Inhibitor, Everolimus (RAD001) Overcomes Resistance to Imatinib In Ph-Leukemia Quiescent Cells.

Methyljasmonate, An Inhibitor of Glycolytic Energy Production, Displays Pre-Clinical Activity against Multiple Myeloma Cells.

Chimeric Regulatory T cells Enhance HSC Engraftment in An Antigen-Specific Fashion.

Antitumor Activity of MLN9708, a Second-Generation Proteasome Inhibitor, in Preclinical Models of Lymphoma.

Pre-Clinical Antitumor activity of MLN4924, An Inhibitor of NEDD8-Activating Enzyme (NAE), in a Novel Primary Human DLBCL Xenograft Model.

Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development

CD8 + /TCR − Facilitating Cells Induce Generation of Regulatory T cells in Vivo: Chimeric Regulatory T Cells are Antigen-Specific and Enhance Engraftment of Allogeneic HSC in Non-Obese Diabetic (NOD) Mice.

Costimulatory Blockade Enhances Engraftment and Prevents Anti-Donor Antibody Generation in Nonmyeloablative Conditioned Prediabetic NOD Mice

Constitutive expression of IL-12Rβ2 on human multiple myeloma cells delineates a novel therapeutic target

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American Society of Hematology

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American Society of Hematology

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