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Hannah M. Jacobs
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Journal Articles

Temporal Dynamics of Tumor-Microenvironment Interaction and Treatment Responses Revealed through Time-Lapse Compartment-Specific Bioluminescence Imaging: Translational implications

Eugen Dhimolea, PhD, Emily King, Efstathios Kastritis, MD, Douglas W. McMillin, PhD, Jake E. Delmore, B.Sc., Joseph M. Negri, B.Sc., Hannah M. Jacobs, B.Sc., Catriona A. Hayes, MD, Michal Sheffer, PhD, Yiguo Hu, PhD, Subhashis Sarkar, PhD, Richard W.J. Groen, PhD, Megan A. Bariteau, B.Sc., Blake T. Aftab, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2014) 124 (21): 276.
https://doi.org/10.1182/blood.V124.21.276.276
Published: 2014
Journal Articles

Cell Non-Autonomous Modulation Of Tumor Cell Responses To Pharmacological Inhibition Of The Proteasome

Eugen Dhimolea, PhD, Richard W.J. Groen, PhD, Catriona A. Hayes, MD, Jana Jakubikova, PhD, Bariteau Megan, Jake E. Delmore, Hannah M. Jacobs, Julio-Cesar Marin, Gregory Della Penna, Douglas W. McMillin, PhD, Ana Acuna, Panisinee Lawasut, MD, Nancy Kohl, PhD, Constantine S. Mitsiades, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4454.
https://doi.org/10.1182/blood.V122.21.4454.4454
Published: 2013
Journal Articles

Cells of the Osteoblast Lineage Confer Myeloma Cell Resistance to Established and Investigational Therapeutic Agents

Catriona A. Hayes, MD, Paul Dowling, PhD, Richard W.J. Groen, PhD, Douglas W. McMillin, PhD, Jake E. Delmore, Hannah M. Jacobs, Niels W.C.J. van de Donk, MD, PhD, Eugen Dhimolea, PhD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Martin Clynes, PhD, Peter O'Gorman, M.D., Constantine S. Mitsiades, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3995.
https://doi.org/10.1182/blood.V120.21.3995.3995
Published: 2012
Journal Articles

Tumor Cell-Dependent Differences in Stroma-Induced Changes to Bortezomib Sensitivity.

Eugen Dhimolea, PhD, Jana Jakubikova, PhD, Richard W.J. Groen, PhD, Jake E. Delmore, Hannah M. Jacobs, Douglas W. McMilllin, Ana Acuña-Villaorduña, MD, Catriona A. Hayes, MD, Panisinee Lawasut, MD, Constantine S. Mitsiades, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2468.
https://doi.org/10.1182/blood.V120.21.2468.2468
Published: 2012
Journal Articles

Proteomic Characterization of An Isogenic Multiple Myeloma Cell Line Model of Bortezomib Resistance

*Catriona A. Hayes, MD, *Paul Dowling, PhD, Joseph Negri, Michael Henry, Leutz Buon, Jana Jakubikova, PhD, Jake E Delmore, Douglas W. McMillin, PhD, Steffen Klippel, PhD, Hannah M. Jacobs, Niels W.C.J. van de Donk, MD, PhD, Eugen Dhimolea, PhD, Panisinee Lawasut, MD, MSc, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Martin Clynes, PhD, *Peter O Gorman, MD, PhD, *Constantine S. Mitsiades, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1820.
https://doi.org/10.1182/blood.V118.21.1820.1820
Published: 2011
Journal Articles

In Vitro Anti-Myeloma Activity of the Multitargeted Kinase Inhibitor Midostaurin in the Context of Heterotypic Cocultures of Myeloma Cells with Nonmalignant Microenvironmental Accessory Cells

Panisinee Lawasut, MD, Hannah M. Jacobs, Jake E Delmore, Joseph Negri, Douglas W. McMillin, PhD, Ellen L Weisberg, Ph.D., James D. Griffin, MD, Paul G. Richardson, MD, Kenneth C Anderson, MD, Constantine S. Mitsiades, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2923.
https://doi.org/10.1182/blood.V118.21.2923.2923
Published: 2011
Journal Articles

Inhibition of c-Myc Expression and Function in Hematologic Malignancies

Ghayas C Issa, MD, Jake E Delmore, Michael R McKeown, Madeleine E Lemieux, Peter B Rahl, Hannah M. Jacobs, Efstathios Kastritis, MD, Timothy Gilpatrick, Ronald M Paranal, Jun Qi, Junwei Shi, Marta Chesi, Anna C. Schinzel, PhD, Christopher R. Vakoc, M.D., Ph.D., P.Leif Bergsagel, MD, Paul G. Richardson, MD, Richard Young, PhD, William C. Hahn, MD, PhD, Irene M. Ghobrial, MD, Kenneth C Anderson, MD, Andrew L. Kung, MD, PhD, Constantine S. Mitsiades, MD, PhD, James E Bradner, MD
Journal: Blood
Blood (2011) 118 (21): 1409.
https://doi.org/10.1182/blood.V118.21.1409.1409
Published: 2011
Journal Articles

Preclinical Studies of Salinomycin In Multiple Myeloma (MM) Models: Targeting of Side Population (SP) Cells In the Context of Tumor – Microenvironment Interactions.

Efstathios Kastritis, Jana Jakubikova, Jake Delmore, Steffen Klippel, Douglas W. McMillin, Melissa Ooi, Hannah M. Jacobs, Jacob P. Laubach, Paul G Richardson, Kenneth C. Anderson, Andrew L. Kung, Constantine S. Mitsiades, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1574.
https://doi.org/10.1182/blood.V116.21.1574.1574
Published: 2010