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Journal Articles

A Caenorhabditis elegans– based assay recognizes immunoglobulin light chains causing heart amyloidosis

Luisa Diomede, Paola Rognoni, Francesca Lavatelli, Margherita Romeo, Elena del Favero, Laura Cantù, Elena Ghibaudi, Andrea di Fonzo, Alessandro Corbelli, Fabio Fiordaliso, Giovanni Palladini, Veronica Valentini, Vittorio Perfetti, Mario Salmona, Giampaolo Merlini

Blood (2014) 123 (23): 3543–3552.

https://doi.org/10.1182/blood-2013-10-525634

Published: 2014

Includes: Supplemental data

Journal Articles

The repertoire of λ light chains causing predominant amyloid heart involvement and identification of a preferentially involved germline gene, IGLV1-44

Vittorio Perfetti, Giovanni Palladini, Simona Casarini, Valentina Navazza, Paola Rognoni, Laura Obici, Rosangela Invernizzi, Stefano Perlini, Catherine Klersy, Giampaolo Merlini

Blood (2012) 119 (1): 144–150.

https://doi.org/10.1182/blood-2011-05-355784

Published: 2012

Journal Articles

FISH reveals chromosomal abnormalities in 41 Patients with Systemic Amyloidosis (AL).

Paolo Bernasconi, MD, Celeste Calvello, PhD, Catherine Klersy, MD, Irene Dambruoso, PhD, Marina Boni, BSc, Stefania Casarin, PhD, Giovanni Paladini, MD, Vittorio Perfetti, MD, Giampaolo Merlini

Blood (2010) 116 (21): 1197.

https://doi.org/10.1182/blood.V116.21.1197.1197

Published: 2010

Journal Articles

Salvage Therapy with Lenalidomide and Dexamethasone (LDex) In Patients with Advanced AL Amyloidosis Refractory to Both Melphalan and Bortezomib

Giovanni Palladini, MD, PhD, Paola Russo, MD, Paolo Milani, MD, Andrea Foli, MD, Letizia Zenone Bragotti, MD, Laura Obici, MD, Francesca Lavatelli, MD, Silvia Brugnatelli, MD, Vittorio Perfetti, MD, PhD, Rosangela Invernizzi, MD, Giampaolo Merlini, MD

Blood (2010) 116 (21): 3062.

https://doi.org/10.1182/blood.V116.21.3062.3062

Published: 2010

Journal Articles

Treatment with Oral Melphalan and Dexamethasone of An Extended Patient Population with AL Amyloidosis.

Giovanni Palladini, Paola Russo, Andrea Foli, Letizia Zenone Bragotti, Francesca Lavatelli, Vittorio Perfetti, Laura Obici, Stefano Perlini, Giampaolo Merlini

Blood (2009) 114 (22): 3889.

https://doi.org/10.1182/blood.V114.22.3889.3889

Published: 2009

Journal Articles

A Phase II Trial of Cyclophosphamide, Lenalidomide and Dexamethasone (CLD) in Previously Treated Patients with AL Amyloidosis.

Giovanni Palladini, Paola Russo, Letizia Zenone Bragotti, Andrea Foli, Francesco Musca, Francesca Lavatelli, Vittorio Perfetti, Laura Obici, Stefano Perlini, Giampaolo Merlini

Blood (2009) 114 (22): 2863.

https://doi.org/10.1182/blood.V114.22.2863.2863

Published: 2009

Journal Articles

Significant Activity of Bortezomib-Based Therapy in Patients with Primary Systemic (AL) Amyloidosis

Efstathios Kastritis, Ashutosh D Wechalekar, Meletios A. Dimopoulos, Giampaolo Merlini, Philip N Hawkins, Vittorio Perfetti, Julian D Gillmore, Giovanni Palladini

Blood (2008) 112 (11): 869.

https://doi.org/10.1182/blood.V112.11.869.869

Published: 2008

Journal Articles

Constitutive expression of IL-12Rβ2 on human multiple myeloma cells delineates a novel therapeutic target

Irma Airoldi, Claudia Cocco, Nicola Giuliani, Marina Ferrarini, Simona Colla, Emanuela Ognio, Giuseppe Taverniti, Emma Di Carlo, Giovanna Cutrona, Vittorio Perfetti, Vittorio Rizzoli, Domenico Ribatti, Vito Pistoia

Blood (2008) 112 (3): 750–759.

https://doi.org/10.1182/blood-2008-02-139378

Published: 2008

Journal Articles

Treatment with oral melphalan plus dexamethasone produces long-term remissions in AL amyloidosis

Giovanni Palladini, Paola Russo, Mario Nuvolone, Francesca Lavatelli, Vittorio Perfetti, Laura Obici, Giampaolo Merlini

Blood (2007) 110 (2): 787–788.

https://doi.org/10.1182/blood-2007-02-076034

Published: 2007

Journal Articles

Early Harvest Followed by Melphalan-Dexamethasone and Second-Line Autologous Stem Cell Transplantation in AL Amyloidosis.

Giovanni Palladini, MD, Vittorio Perfetti, MD, Paola Russo, MD, Francesca Lavatelli, MD, Mario Nuvolone, MD, Laura Obici, MD, Giampaolo Merlini, MD

Blood (2006) 108 (11): 5449.

https://doi.org/10.1182/blood.V108.11.5449.5449

Published: 2006

Journal Articles

Circulating amyloidogenic free light chains and serum N-terminal natriuretic peptide type B decrease simultaneously in association with improvement of survival in AL

Giovanni Palladini, Francesca Lavatelli, Paola Russo, Stefano Perlini, Vittorio Perfetti, Tiziana Bosoni, Laura Obici, Arthur R. Bradwell, GianVico Melzi D'Eril, Roberto Fogari, Remigio Moratti, Giampaolo Merlini

Blood (2006) 107 (10): 3854–3858.

https://doi.org/10.1182/blood-2005-11-4385

Published: 2006

Journal Articles

Evolution of a True B-Cell Chronic Lymphocytic Leukaemia (B-CLL) in a Diffuse Immunocytoma after Treatment with Fludarabine.

Paolo Bernasconi, MD, Marco Paulli, MD, Ester Orlandi, MD, Vittorio Perfetti, MD, Ilaria Giardini, MD, Silvia Zibellini, MD, Laura Vanelli, MD, Annamaria Tenore, MD, Marina Boni, MD, Paola Maria Cavigliano, MD, Alessandra Algarotti, MD, Ercole Brusamolino, MD, Mario Lazzarino, MD

Blood (2005) 106 (11): 4973.

https://doi.org/10.1182/blood.V106.11.4973.4973

Published: 2005

Journal Articles

The combination of thalidomide and intermediate-dose dexamethasone is an effective but toxic treatment for patients with primary amyloidosis (AL)

Giovanni Palladini, Vittorio Perfetti, Stefano Perlini, Laura Obici, Francesca Lavatelli, Riccardo Caccialanza, Rosangela Invernizzi, Benedetto Comotti, Giampaolo Merlini

Blood (2005) 105 (7): 2949–2951.

https://doi.org/10.1182/blood-2004-08-3231

Published: 2005

Journal Articles

Human Monoclonal Cryocrystalglobulinemia: First Complete Heavy and Light Chain Variable Region Nucleotide Sequences.

Vittorio Perfetti, MD, Valentina Navazza, PhD, Sofia Giorgietti, PhD, Loredana Marchese, PhD, Giovanni Palladini, MD, Roberto Caporali, MD, Claudio Montecucco, MD, Giampaolo Merlini, MD

Blood (2004) 104 (11): 1381.

https://doi.org/10.1182/blood.V104.11.1381.1381

Published: 2004

Journal Articles

Association of melphalan and high-dose dexamethasone is effective and well tolerated in patients with AL (primary) amyloidosis who are ineligible for stem cell transplantation

Giovanni Palladini, Vittorio Perfetti, Laura Obici, Riccardo Caccialanza, Alessandra Semino, Fausto Adami, Giobatta Cavallero, Roberto Rustichelli, Giovambattista Virga, Giampaolo Merlini

Blood (2004) 103 (8): 2936–2938.

https://doi.org/10.1182/blood-2003-08-2788

Published: 2004

Journal Articles

Analysis of Vλ-Jλ expression in plasma cells from primary (AL) amyloidosis and normal bone marrow identifies 3r (λIII) as a new amyloid-associated germline gene segment

Vittorio Perfetti, Simona Casarini, Giovanni Palladini, Maurizio Colli Vignarelli, Catherine Klersy, Marta Diegoli, Edoardo Ascari, Giampaolo Merlini

Blood (2002) 100 (3): 948–953.

https://doi.org/10.1182/blood-2002-01-0114

Published: 2002

Journal Articles

Treatment of AL Amyloidosis with 4′-Iodo-4′-Deoxydoxorubicin: An Update

Giampaolo Merlini, Ernesto Anesi, Pietro Garini, Vittorio Perfetti, Laura Obici, Edoardo Ascari, Maria J. Lechuga, Giuseppe Capri, Luca Gianni

Blood (1999) 93 (3): 1112–1113.

https://doi.org/10.1182/blood.V93.3.1112

Published: 1999

Journal Articles

Evidence That Amyloidogenic Light Chains Undergo Antigen-Driven Selection

Vittorio Perfetti, Paola Ubbiali, Maurizio Colli Vignarelli, Marta Diegoli, Roberta Fasani, Monica Stoppini, Antonella Lisa, Palma Mangione, Laura Obici, Eloisa Arbustini, Giampaolo Merlini

Blood (1998) 91 (8): 2948–2954.

https://doi.org/10.1182/blood.V91.8.2948.2948_2948_2954

Published: 1998

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A Caenorhabditis elegans– based assay recognizes immunoglobulin light chains causing heart amyloidosis

The repertoire of λ light chains causing predominant amyloid heart involvement and identification of a preferentially involved germline gene, IGLV1-44

FISH reveals chromosomal abnormalities in 41 Patients with Systemic Amyloidosis (AL).

Salvage Therapy with Lenalidomide and Dexamethasone (LDex) In Patients with Advanced AL Amyloidosis Refractory to Both Melphalan and Bortezomib

Treatment with Oral Melphalan and Dexamethasone of An Extended Patient Population with AL Amyloidosis.

A Phase II Trial of Cyclophosphamide, Lenalidomide and Dexamethasone (CLD) in Previously Treated Patients with AL Amyloidosis.

Significant Activity of Bortezomib-Based Therapy in Patients with Primary Systemic (AL) Amyloidosis

Constitutive expression of IL-12Rβ2 on human multiple myeloma cells delineates a novel therapeutic target

Treatment with oral melphalan plus dexamethasone produces long-term remissions in AL amyloidosis

Early Harvest Followed by Melphalan-Dexamethasone and Second-Line Autologous Stem Cell Transplantation in AL Amyloidosis.

Circulating amyloidogenic free light chains and serum N-terminal natriuretic peptide type B decrease simultaneously in association with improvement of survival in AL

Evolution of a True B-Cell Chronic Lymphocytic Leukaemia (B-CLL) in a Diffuse Immunocytoma after Treatment with Fludarabine.

The combination of thalidomide and intermediate-dose dexamethasone is an effective but toxic treatment for patients with primary amyloidosis (AL)

Human Monoclonal Cryocrystalglobulinemia: First Complete Heavy and Light Chain Variable Region Nucleotide Sequences.

Association of melphalan and high-dose dexamethasone is effective and well tolerated in patients with AL (primary) amyloidosis who are ineligible for stem cell transplantation

Analysis of Vλ-Jλ expression in plasma cells from primary (AL) amyloidosis and normal bone marrow identifies 3r (λIII) as a new amyloid-associated germline gene segment

Treatment of AL Amyloidosis with 4′-Iodo-4′-Deoxydoxorubicin: An Update

Evidence That Amyloidogenic Light Chains Undergo Antigen-Driven Selection

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