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Journal Articles

Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis

Aleksandra S. Dain, MD, Michelle L. Hermiston, MD PhD, Kristin A. Shimano, MD, Sandhya Kharbanda, MD, Alexis Melton, MD PhD, Jasmeen Dara, MD, James N Huang, MD, Christopher C. Dvorak, MD

Blood (2019) 134 (Supplement_1): 3343.

https://doi.org/10.1182/blood-2019-127397

Published: 2019

Journal Articles

Early B Cell Development Is Impaired in Patients with Active Hemophagocytic Lymphohistiocytosis

Jenny Shim, MD, Sunita Park, MD, Shanmuganathan Chandrakasan, MD

Blood (2017) 130 (Supplement 1): 1006.

https://doi.org/10.1182/blood.V130.Suppl_1.1006.1006

Published: 2017

Journal Articles

Excellent Outcomes in Children and Young Adults Using Reduced-Intensity Conditioning for Patients with Inborn Errors of Immunity, Hematopoiesis, and Metabolism with Single-Unit Cord Blood or Bone Marrow

Mark Vander Lugt, MD, Hey Jin Chong, MD PhD, Xiaohua Chen, MDPhD, Randy M. Windreich, MD, Rakesh Goyal, MD MRCP, Maria Escolar, MD, Paul Szabolcs, MD

Blood (2015) 126 (23): 4329.

https://doi.org/10.1182/blood.V126.23.4329.4329

Published: 2015

Journal Articles

A Novel Targeted Approach to the Treatment of Hemophagocytic Lymphohistiocytosis (HLH) with an Anti-Interferon Gamma (IFNγ) Monoclonal Antibody (mAb), NI-0501: First Results from a Pilot Phase 2 Study in Children with Primary HLH

Michael Jordan, MD, Franco Locatelli Prof, MD, PhD, Carl Allen, MD, PhD, Fabrizio De Benedetti, MD, PhD, Alexei A. Grom, Maria Ballabio, MD, Walter Giovanni Ferlin, PhD, NI-0501-04 Study Group, Cristina De Min, MD

Blood (2015) 126 (23): LBA-3.

https://doi.org/10.1182/blood.V126.23.LBA-3.LBA-3

Published: 2015

Journal Articles

Hemophagocytic Lymphohistiocytosis Associated with NK Cell Dysfunction and Disseminated Herpesvirus Infection in GATA2 Deficiency/Monomac Syndrome

Michael A. Spinner, MD, Camila Odio, B.S., Katherine R. Calvo, MD, PhD, Amy P Hsu, B.A., Christa S. Zerbe, MD, Jennifer Cuellar-Rodriguez, MD, Jennifer P. Ker, MD, Charles J. Stoudenmire, MD, Oluwole Fadare, MD, Arunima Ghosh, MD,PhD, Emily M. Mace, PhD, Jordan S. Orange, MD, PhD, Dennis D. Hickstein, MD, Steven M. Holland, MD

Blood (2014) 124 (21): 4978.

https://doi.org/10.1182/blood.V124.21.4978.4978

Published: 2014

Journal Articles

Inability to resolve specific infection generates innate immunodeficiency syndrome in Xiap −/− mice

Wan-Chen Hsieh, Ya-Ting Chuang, I-Hsuan Chiang, Shu-Ching Hsu, Shi-Chuen Miaw, Ming-Zong Lai

Blood (2014) 124 (18): 2847–2857.

https://doi.org/10.1182/blood-2014-03-564609

Published: 2014

Includes: Supplemental data

Journal Articles

Successful stem cell transplant with antibody-based conditioning for XIAP deficiency with refractory hemophagocytic lymphohistiocytosis

Austen J. J. Worth, Olga Nikolajeva, Robert Chiesa, Kanchan Rao, Paul Veys, Persis J. Amrolia

Blood (2013) 121 (24): 4966–4968.

https://doi.org/10.1182/blood-2013-01-478735

Published: 2013

Journal Articles

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes

Blood (2013) 121 (6): 877–883.

https://doi.org/10.1182/blood-2012-06-432500

Published: 2013

Journal Articles

Hemophagocytic Lymphohistiocytosis: Update of Biology and Treatment Options

Alexandra H. Filipovich, MD

Blood (2012) 120 (21): SCI-9.

https://doi.org/10.1182/blood.V120.21.SCI-9.SCI-9

Published: 2012

Journal Articles

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)

Blood (2011) 117 (5): 1522–1529.

https://doi.org/10.1182/blood-2010-07-298372

Published: 2011

Includes: Supplemental data

Journal Articles

Germline Mutations within the IL2-Inducible T Cell Kinase Impede T Cell Differentiation or Survival, Cause Protein Destabilisation, Loss of Membrane Recruitment and Lead to Severe EBV Lymphoproliferation

Rene Martin Linka, Kirsten Huck, Frank Krux, Polina Stepenski, Cindy Synaeve, Kim Vettenranta, MD, PhD, Rene Deenen, Ingrid Müller-Fleckenstein, Yvonne Linka, Sebastian Ginzel, Anne Halenius, Karl Köhrer, Bernhard Fleckenstein, Hans Jürgen Laws, Roland Hartig, Burkhart Schraven, Sylvain Latour, Arndt Borkhardt, MD

Blood (2010) 116 (21): 280.

https://doi.org/10.1182/blood.V116.21.280.280

Published: 2010

Journal Articles

X-linked lymphoproliferative syndromes: brothers or distant cousins?

Alexandra H. Filipovich, Kejian Zhang, Andrew L. Snow, Rebecca A. Marsh

Blood (2010) 116 (18): 3398–3408.

https://doi.org/10.1182/blood-2010-03-275909

Published: 2010

Journal Articles

XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease

Rebecca A. Marsh, Lisa Madden, Brenda J. Kitchen, Rajen Mody, Brad McClimon, Michael B. Jordan, Jack J. Bleesing, Kejian Zhang, Alexandra H. Filipovich

Blood (2010) 116 (7): 1079–1082.

https://doi.org/10.1182/blood-2010-01-256099

Published: 2010

Includes: Supplemental data

NARROW

Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis

Early B Cell Development Is Impaired in Patients with Active Hemophagocytic Lymphohistiocytosis

Excellent Outcomes in Children and Young Adults Using Reduced-Intensity Conditioning for Patients with Inborn Errors of Immunity, Hematopoiesis, and Metabolism with Single-Unit Cord Blood or Bone Marrow

A Novel Targeted Approach to the Treatment of Hemophagocytic Lymphohistiocytosis (HLH) with an Anti-Interferon Gamma (IFNγ) Monoclonal Antibody (mAb), NI-0501: First Results from a Pilot Phase 2 Study in Children with Primary HLH

Hemophagocytic Lymphohistiocytosis Associated with NK Cell Dysfunction and Disseminated Herpesvirus Infection in GATA2 Deficiency/Monomac Syndrome

Inability to resolve specific infection generates innate immunodeficiency syndrome in Xiap −/− mice

Successful stem cell transplant with antibody-based conditioning for XIAP deficiency with refractory hemophagocytic lymphohistiocytosis

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes

Hemophagocytic Lymphohistiocytosis: Update of Biology and Treatment Options

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)

Germline Mutations within the IL2-Inducible T Cell Kinase Impede T Cell Differentiation or Survival, Cause Protein Destabilisation, Loss of Membrane Recruitment and Lead to Severe EBV Lymphoproliferation

X-linked lymphoproliferative syndromes: brothers or distant cousins?

XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease

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American Society of Hematology

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ASH Publications

American Society of Hematology

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