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Jean-Louis Stephan
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Journal Articles

Circulating Cell-Free DNA in Classical Hodgkin Lymphoma in Children, Adolescents and Young Adults. Results from the Holy Study, a French Ancillary Study of Euronet PHL-C2 Protocol

Mathieu Simonin, Mathieu Viennot, Stéphanie Haouy, Stéphane Ducassou, Aurélie Phulpin, Nathalie Garnier, Catherine Curtillet, Catherine Paillard, Melissa Barbati, Jacinthe Bonneau-Lagacherie, Marie-Laure Couec, Frederic Millot, Liana Carausu, Justyna Kanold, Isabelle Pellier, Pascale Schneider, Jean-Louis Stephan, Camille Leglise, Claire Pluchart, Charlotte Rigaud, Marie-Emilie Dourthe, Pierre-Julien Viailly, Pascaline Etancelin, Victor Michel, Sabah Boudjemaa, Bénédicte Jonca, Françoise Montravers, Thierry Leblanc, Judith Landman-Parker, Fabrice Jardin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1592.
https://doi.org/10.1182/blood-2024-194387
Published: 2024
Journal Articles

Antinuclear antibody–associated autoimmune cytopenia in childhood is a risk factor for systemic lupus erythematosus

Clinical Trials & Observations
Jérôme Granel, Helder Fernandes, Brigitte Bader-Meunier, Amandine Guth, Olivier Richer, Pascal Pillet, Guy Leverger, Stéphane Ducassou, Mony Fahd, Marlène Pasquet, Nathalie Garnier, Vincent Barlogis, Corinne Guitton, Eric Jeziorski, Caroline Thomas, Sophie Bayart, Nathalie Cheikh, Catherine Paillard, Wadih Abou Chahla, Pascal Chastagner, Bénédicte Neven, Frédéric Millot, Julien Lejeune, Valérie Li-Thiao Te, Corinne Armari-Alla, Claire Briandet, Liana Carausu, Marianna Deparis, Christophe Piguet, Joy Benadiba, Aude Marie-Cardine, Jean-Louis Stephan, Isabelle Pellier, Claire Pluchart, Eric Doré, Katell Michaux, Sébastien Héritier, Thierry Leblanc, Nathalie Aladjidi
Journal: Blood
Blood (2024) 143 (16): 1576–1585.
https://doi.org/10.1182/blood.2023021884
Published: 2024
Includes: Supplemental data
Journal Articles

Determinants of long-term outcomes of splenectomy in pediatric autoimmune cytopenias

Clinical Trials & Observations
Thomas Pincez, Nathalie Aladjidi, Sébastien Héritier, Nathalie Garnier, Mony Fahd, Wadih Abou Chahla, Helder Fernandes, Claire Dichamp, Stéphane Ducassou, Marlène Pasquet, Sophie Bayart, Despina Moshous, Nathalie Cheikh, Catherine Paillard, Dominique Plantaz, Eric Jeziorski, Caroline Thomas, Corinne Guitton, Marianna Deparis, Aude Marie Cardine, Jean-Louis Stephan, Isabelle Pellier, Eric Doré, Joy Benadiba, Claire Pluchart, Claire Briandet, Vincent Barlogis, Guy Leverger, Thierry Leblanc
Journal: Blood
Blood (2022) 140 (3): 253–261.
https://doi.org/10.1182/blood.2022015508
Published: 2022
Includes: Supplemental data
Journal Articles

Impact and Dynamics of TP53 Mutated Clones in Shwachman Diamond Syndrome in a Series of 80 Patients

Jean-Alain Martignoles, Pierre Hirsch, MD PhD, Blandine Beaupain, Thomas Longval, MD, Nawa Hachem, MsC, Mira El-Khoury, PhD, Sophie Kaltenbach, Jean Soulier, MDPhD, Thierry Leblanc, MD, Pierre Simon Rohrlich, MDPhD, Eric Jeziorski, MDPhD, Isabelle Meyts, Dalila Adjaoud, MD, Vincent Barlogis, MD, PhD, Marlène Pasquet, MD, PhD, Laetitia Largeaud, Flore Sicre de Fontbrune, Claire Fieschi, MD PhD, Virginie Gandemer, MD PhD, Nathalie Aladjidi, MD, Fanny Fouyssac, MD, Guy Leverger, MD, Wadih Abou Chahla, MD, Stephane Blanche, MD, Despina Moushous, MD PhD, Aline Moignet Autrel, MD, Yves Bertrand, MD, Cecile Renard, Pascale Flandrin-Gresta, MD, Jean Louis Stephan, MDPhD, Olivier Tournilhac, MD PhD, Liana Carausu, Frederic Millot, MD, Marielaure Couec, MD, Claude Preudhomme, MD PhD, Hélène Lapillonne, MD PhD, Vahid Asnafi, MD PhD, Patrick Revy, Christine Bellanne-Chantelot, PhD PharmD, Francois Delhommeau, MD PhD, Jean Donadieu, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-138540
Published: 2020
Journal Articles

Alemtuzumab as First Line Treatment in Children with Familial Lymphohistiocytosis

Despina Moshous, MD PhD, Coralie Briand, MD, Martin Castelle, MD, Laurent Dupic, MD, Guillaume Morelle, MD, Wadih Abou Chahla, MD, Vincent Barlogis, MD PhD, Yves Bertrand, MD, Bénédicte Bruno, MD, Eric Jeziorski, MD PhD, Catherine Paillard, MD PhD, Pierre Simon Rohrlich, MD PhD, Jean Louis Stephan, MD PhD, Caroline Thomas, MD, Stéphanie Chhun, PharmD, PhD, Isabelle Pellier, MD PhD, Aude Marie-Cardine, MD, Mathieu Fusaro, Genevieve de Saint Basile, MD PhD, Capucine Picard, MD PhD, Caroline Elie, MD PhD, Benedicte Neven, MD PhD, Stephane Blanche, MD, Alain Fischer, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 80.
https://doi.org/10.1182/blood-2019-124477
Published: 2019
Journal Articles

Expanded Access Program of Graspa for Treatment of Patients with Acute Lymphoblastic Leukemia Unable to Receive Other Form of L-Asparaginase - a Status Update (NCT02197650)

Yves Bertrand, MDPhD, Hervé Dombret, Bruno Quesnel, MD PhD, Jean-Louis Stephan, MD, Claudine Schmitt, MD, Severine Lissandre, MD, Maryline Poiree, MD, Christian Recher, MDPhD, Emmanuel Plouvier, MD, Cécile Dumesnil de Maricourt, MD, David Salako, MSc, Yann Godfrin, PhD, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 4877.
https://doi.org/10.1182/blood.V126.23.4877.4877
Published: 2015
Journal Articles

Evaluation of the Impact of the Presence of Neutralizing L-Asparaginase Antibodies on the Efficacy and Safety of Graspa in Phase 3 Randomized Trial Versus Native L-Asparaginase in Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Yves Bertrand, MDPhD, Andre Baruchel, MD, Xavier Thomas, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, Genevieve Plat, MD, Jose Fernandes, MD, Maryline Poiree, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Dominique Plantaz, MDPhD, Stephane Lepretre, MD, Alina Ferster, MD PhD, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, Cecile Bonin, Pharm D, Yann Godfrin, PhD, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 3734.
https://doi.org/10.1182/blood.V126.23.3734.3734
Published: 2015
Journal Articles

Updated Clinical Activity of Graspa Versus Native l-Asparaginase in Combination with Cooprall Regimen in Phase 3 Randomized Trial in Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Andre Baruchel, MD, Yves Bertrand, MD PhD, Xavier Thomas, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, MDPhD, Genevieve PLAT, Jose Fernandes, MD, Poiree Maryline, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Dominique Plantaz, MDPhD, Stephane Lepretre, MD, Alina Ferster, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, MD, Cecile Bonin, Pharm D, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 3723.
https://doi.org/10.1182/blood.V126.23.3723.3723
Published: 2015
Journal Articles

Pharmacokinetic and Pharmacodynamic Characterization of Graspa Versus Native L-Asparaginase in Combination with Cooprall Chemotherapy in a Phase 3 Randomized Trial for the Treatment of Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Xavier Thomas, MD PhD, Yves Bertrand, MDPhD, Andre Baruchel, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, Genevieve Plat, MD, Jose Fernandes, MD, Maryline Poiree, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Stephane Lepretre, MD, Alina Ferster, MD PhD, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, Cecile Bonin, Pharm D, Yann Godfrin, PhD, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 2492.
https://doi.org/10.1182/blood.V126.23.2492.2492
Published: 2015
Journal Articles

Human X-linked variable immunodeficiency caused by a hypomorphic mutation in XIAP in association with a rare polymorphism in CD40LG

Clinical Trials & Observations
Stéphanie Rigaud, Eduardo Lopez-Granados, Sophie Sibéril, Geoffrey Gloire, Nathalie Lambert, Christelle Lenoir, Cindy Synaeve, Maria Stacey, Lars Fugger, Jean-Louis Stephan, Alain Fischer, Capucine Picard, Anne Durandy, Helen Chapel, Sylvain Latour
Journal: Blood
Blood (2011) 118 (2): 252–261.
https://doi.org/10.1182/blood-2011-01-328849
Published: 2011
Includes: Supplemental data
Journal Articles

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)

Clinical Trials & Observations
Jana Pachlopnik Schmid, Danielle Canioni, Despina Moshous, Fabien Touzot, Nizar Mahlaoui, Fabian Hauck, Hirokazu Kanegane, Eduardo Lopez-Granados, Ester Mejstrikova, Isabelle Pellier, Lionel Galicier, Claire Galambrun, Vincent Barlogis, Pierre Bordigoni, Alain Fourmaintraux, Mohamed Hamidou, Alain Dabadie, Françoise Le Deist, Filomeen Haerynck, Marie Ouachée-Chardin, Pierre Rohrlich, Jean-Louis Stephan, Christelle Lenoir, Stéphanie Rigaud, Nathalie Lambert, Michèle Milili, Claudin Schiff, Helen Chapel, Capucine Picard, Geneviève de Saint Basile, Stéphane Blanche, Alain Fischer, Sylvain Latour
Journal: Blood
Blood (2011) 117 (5): 1522–1529.
https://doi.org/10.1182/blood-2010-07-298372
Published: 2011
Includes: Supplemental data
Journal Articles

Related Myeloablative Stem Cell Transplantation (SCT) to Cure Sickle Cell Anemia (SCA): Update of French Results

Francoise Bernaudin, Marie Robin, Christèle Ferry, Karima Yacouben, Jean-Hugues Dalle, Régis Peffault de Latour, Yves Bertrand, Corinne Pondarre, Mathieu Kuentz, Jean-Pierre Vannier, Alain Fischer, Isabelle Thuret, Patrick Lutz, Pierre Bordigoni, Pierre Rohrlich, Jean-Louis Stephan, Nathalie Dhedin, Jean Paul Vernant, Jean-Yves Cahn, Francois Demeocq, Bernard Rio, Dominique Bories, Eliane Gluckman, Gérard Socié
Journal: Blood
Blood (2010) 116 (21): 3518.
https://doi.org/10.1182/blood.V116.21.3518.3518
Published: 2010
Journal Articles

High Pro-Apoptotic Effects of 17-Allylamino-17-Demethoxy Geldanamycin (17-AAG) In Philadelphia Acute Lymphoblastic Leukemia (Ph+ ALL)

Emmanuelle Tavernier-Tardy, Pascale Flandrin, Francoise Solly, Jérôme Cornillon, Karine Augeul-Meunier, Jean-Louis Stephan, Denis Guyotat, Lydia Campos, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3226.
https://doi.org/10.1182/blood.V116.21.3226.3226
Published: 2010
Journal Articles

A role for interleukin-12/23 in the maturation of human natural killer and CD56 + T cells in vivo

Sophie Guia, Céline Cognet, Ludovic de Beaucoudrey, Marlowe S. Tessmer, Emmanuelle Jouanguy, Claire Berger, Orchidée Filipe-Santos, Jacqueline Feinberg, Yildiz Camcioglu, Jacob Levy, Suliman Al Jumaah, Sami Al-Hajjar, Jean-Louis Stephan, Claire Fieschi, Laurent Abel, Laurent Brossay, Jean-Laurent Casanova, Eric Vivier
Journal: Blood
Blood (2008) 111 (10): 5008–5016.
https://doi.org/10.1182/blood-2007-11-122259
Published: 2008
Includes: Supplemental data
Journal Articles

Long-term results of related myeloablative stem-cell transplantation to cure sickle cell disease

Françoise Bernaudin, Gérard Socie, Mathieu Kuentz, Sylvie Chevret, Michel Duval, Yves Bertrand, Jean-Pierre Vannier, Karima Yakouben, Isabelle Thuret, Pierre Bordigoni, Alain Fischer, Patrick Lutz, Jean-Louis Stephan, Nathalie Dhedin, Emmanuel Plouvier, Geneviève Margueritte, Dominique Bories, Suzanne Verlhac, Hélène Esperou, Lena Coic, Jean-Paul Vernant, Eliane Gluckman
Journal: Blood
Blood (2007) 110 (7): 2749–2756.
https://doi.org/10.1182/blood-2007-03-079665
Published: 2007