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Journal Articles

Familial patterns of hematologic precursors

Ola Landgren, Francesco Maura

Blood (2021) 137 (15): 1992–1993.

https://doi.org/10.1182/blood.2020010035

Published: 2021

Journal Articles

Epigenomics in Waldenström macroglobulinemia

Zachary R. Hunter, Steven P. Treon

Blood (2020) 136 (5): 527–529.

https://doi.org/10.1182/blood.2020006244

Published: 2020

Journal Articles

Clinical Categorization of Chronic Myelomonocytic Leukemia into Proliferative and Dysplastic Subtypes Correlates with Distinct Genomic, Transcriptomic and Epigenomic Signatures

Blood (2019) 134 (Supplement_1): 1710.

https://doi.org/10.1182/blood-2019-123877

Published: 2019

Journal Articles

Epigenomic Determinants of Transcriptional Activity in ASXL1 -Mutant Chronic Myelomonocytic Leukemia

Moritz Binder, MDMPH, Alexandre Gaspar Maia, PhD, Ryan M. Carr, MD PhD, Christopher Pin, PhD, Kurt Berger, Bonnie Alver, PhD, Keith Robertson, PhD, David Marks, PhD, Martin Fernandez-Zapico, MD, Mrinal M Patnaik, MDMBBS

Blood (2019) 134 (Supplement_1): 2987.

https://doi.org/10.1182/blood-2019-123191

Published: 2019

Journal Articles

Core Transcriptional Regulatory Circuitries in AML

Maxim Pimkin, MD PhD, Juliana Xavier Ferrucio, PhD, Neekesh Vijay Dharia, MD PhD, Taku Harada, Andrew Kossenkov, Selma Elsarrag, Jazmin Ewers, Charles Y Lin, PhD, Kimberly Stegmaier, MD, Stuart H. Orkin, MD

Blood (2019) 134 (Supplement_1): 280.

https://doi.org/10.1182/blood-2019-129297

Published: 2019

Journal Articles

Epigenomic Signatures in Myelodysplastic Syndrome Patients As Predictors of Donor Compatibility and Transplant Outcome

Wei Wang, Paul Auer, PhD, Stephen R. Spellman, MS, Karen-Sue B. Carlson, MD PhD, Aziz Nazha, MD, Martin Maiers, MS, Yung-Tsi Bolon, Wael Saber, MD MS

Blood (2019) 134 (Supplement_1): 4557.

https://doi.org/10.1182/blood-2019-127124

Published: 2019

Journal Articles

Myc and Bet Proteins Orchestrate the Early Regulatory Genome Changes Required for Osteoclast Lineage Commitment

Valentina S Caputo, Nikolaos Trasanidis, Xiaolin Xiao, Mark E Robinson, Alexia Katsarou, Kanagaraju Ponnusamy, Aristeidis Chaidos, Holger W Auner, MD PhD, Irene Roberts, Anastasios Karadimitris

Blood (2019) 134 (Supplement_1): 4329.

https://doi.org/10.1182/blood-2019-125047

Published: 2019

Journal Articles

Chromosomal Loop Editing Reveals New Epigenomic Landscape in the β-Globin Locus with Implications for Hemoglobinopathy Therapies

Pamela Himadewi, BSc, Xiaotian Zhang, PhDBS, Haley Gore, MS, Xue Qing David Wang, PhD

Blood (2019) 134 (Supplement_1): 813.

https://doi.org/10.1182/blood-2019-125020

Published: 2019

Journal Articles

Tet2 Deficiency in Macrophages Undermines Heart Repair after Infarction

Shaohai Fang, MS, Yang Xiao, PhD, Jia Li, PhD, Tingting Li, MD, Hongxiang Zeng, PhD, Wei Han, MS, Yubin Zhou, PhD, Deqiang Sun, PhD, James M. Martin, MD, Yun Huang, PhD

Blood (2018) 132 (Supplement 1): 2394.

https://doi.org/10.1182/blood-2018-99-115358

Published: 2018

Journal Articles

Induced Transdifferentiation of Leukemia B-Cells to Macrophages Involves Reconfiguration of the DNA Methylome

Alberto Bueno-Costa, David Piñeyro, Marta Soler, Biola Maria Javierre, José Angel Martínez-Climent, Manel Esteller, MD PhD

Blood (2018) 132 (Supplement 1): 5115.

https://doi.org/10.1182/blood-2018-99-111580

Published: 2018

Journal Articles

Reciprocal Regulation of BCL6 and MLL Expression As a Vulnerability in MLL -Rearranged Acute Lymphoblastic Leukemia

Lai N Chan, Christian Hurtz, PhD, Huimin Geng, PhD, Cheryl L. Willman, MD, William L. Carroll, MD, Scott Armstrong, MD PhD, Thomas Arthur Milne, PhD BSc, MSc, Markus Muschen, MD

Blood (2017) 130 (Supplement 1): 1210.

https://doi.org/10.1182/blood.V130.Suppl_1.1210.1210

Published: 2017

Journal Articles

Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation

Franco Izzo, PhD, Asaf Poran, Stanley Chun-Wei Lee, PhD, Ronan Chaligne, PhD, Federico Gaiti, PhD, Steven Kothen-Hill, MS, Rafael Schulman, BS, Michelle Ki, Kenigsberg Ephraim, PhD, Omar Abdel-Wahab, MD, Dan A. Landau, MD PhD

Blood (2017) 130 (Supplement 1): 559.

https://doi.org/10.1182/blood.V130.Suppl_1.559.559

Published: 2017

Journal Articles

Comprehensive Population-Based Genetic Fine Mapping and Single-Cell Epigenomics Provide Insights into the Regulation of Human Hematopoiesis

Erik L. Bao, BS, Jacob C. Ulirsch, BS, Caleb A. Lareau, MA, Michael H. Guo, PhD, Rany M. Salem, PhD, Christian Benner, MS, Joel N. Hirschhorn, PhD, Martin J. Aryee, PhD, William J. Greenleaf, PhD, Jason D. Buenrostro, PhD, Vijay G. Sankaran, MD

Blood (2017) 130 (Supplement 1): 2429.

https://doi.org/10.1182/blood.V130.Suppl_1.2429.2429

Published: 2017

Journal Articles

PDX Models Recapitulate Genetics and Epigenetics of Pediatric T-Cell Leukemia

Blood (2017) 130 (Supplement 1): 2723.

https://doi.org/10.1182/blood.V130.Suppl_1.2723.2723

Published: 2017

Journal Articles

Integrative Epigenomics Reveals Novel Chronic Lymphocytic Leukemia-Specific Chromatin States Associated with Epigenetic and Transcriptional Heterogeneity

Alessandro Pastore, MD, Federico Gaiti, PhD, Sydney X. Lu, MDPhD, Omar Abdel-Wahab, MD, Dan A. Landau, MD

Blood (2017) 130 (Supplement 1): 1723.

https://doi.org/10.1182/blood.V130.Suppl_1.1723.1723

Published: 2017

Journal Articles

Dot1l Reverses the Abnormal Self-Renewal Conferred on HSPCs through Cohesin Haploinsufficiency By Diminishing Expression of Hoxa7 and Hoxa9

Joseph B Fisher, PhD, Cary Stelloh, Emily Kristine Phillips, BS, Katelyn Heimbruch, BS, Alison E Meyer, PhD, Kirthi Pulakanti, Maureen McNulty, BS, Aaron D Viny, MDMS, Ross L. Levine, MD, John D. Crispino, PhD, Sridhar Rao, MD PhD

Blood (2017) 130 (Supplement 1): 246.

https://doi.org/10.1182/blood.V130.Suppl_1.246.246

Published: 2017

Journal Articles

Clinical Pharmacodynamic Markers and Combinations with SY1425 (tamibarotene) in a Genomically-Defined Subset of Non-APL AML

Michael R McKeown, PhD, Christopher Fiore, PhD, Emily Lee, BS, Matthew L Eaton, PhD, Christian C. Fritz, PhD

Blood (2016) 128 (22): 2898.

https://doi.org/10.1182/blood.V128.22.2898.2898

Published: 2016

Journal Articles

A Pharmacologically Reversible Epigenomic Signature of Relapse and Chemotherapy Resistance in Anaplastic Large Cell Lymphoma

Heng Pan, BS, Marcello Gaudiano, Fabrizio Tabbo', Elisa de Stanchina, Peter Martin, MD, Olivier Elemento, PhD, Giorgio Inghirami, MD

Blood (2016) 128 (22): 3932.

https://doi.org/10.1182/blood.V128.22.3932.3932

Published: 2016

Journal Articles

Aging Human Hematopoietic Stem Cells Manifest Massive Epigenetic Reprogramming and Altered Gene Splicing of Key Hematopoietic Gene Sets

Emmalee R Adelman, Jian Shi, Maria E Figueroa, MD

Blood (2016) 128 (22): 885.

https://doi.org/10.1182/blood.V128.22.885.885

Published: 2016

Journal Articles

Polycomb-Dependent Epigenetic Landscape in Adult T Cell Leukemia (ATL); Providing Proof of Concept for Targeting EZH1/2 to Selectively Eliminate the HTLV-1 Infected Population

Makoto Yamagishi, PhD, Dai Fujikawa, Daisuke Honma, PhD, Nobuaki Adachi, PhD, Shota Nakagawa, Makoto Hori, Naoya Kurokawa, Ai Soejima, Kazumi Nakano, PhD, Tadanori Yamochi, PhD, Makoto Nakashima, Seiichiro Kobayashi, MD, PhD, Yuetsu Tanaka, MD, PhD, Masako Iwanaga, MD, PhD, Atae Utsunomiya, MD, PhD, Kaoru Uchimaru, MD, PhD, Kunihiro Tsukasaki, MD, PhD, Kazushi Araki, D.V.M., PhD, Toshiki Watanabe, MD, PhD

Blood (2015) 126 (23): 572.

https://doi.org/10.1182/blood.V126.23.572.572

Published: 2015

NARROW

Familial patterns of hematologic precursors

Epigenomics in Waldenström macroglobulinemia

Clinical Categorization of Chronic Myelomonocytic Leukemia into Proliferative and Dysplastic Subtypes Correlates with Distinct Genomic, Transcriptomic and Epigenomic Signatures

Epigenomic Determinants of Transcriptional Activity in ASXL1 -Mutant Chronic Myelomonocytic Leukemia

Core Transcriptional Regulatory Circuitries in AML

Epigenomic Signatures in Myelodysplastic Syndrome Patients As Predictors of Donor Compatibility and Transplant Outcome

Myc and Bet Proteins Orchestrate the Early Regulatory Genome Changes Required for Osteoclast Lineage Commitment

Chromosomal Loop Editing Reveals New Epigenomic Landscape in the β-Globin Locus with Implications for Hemoglobinopathy Therapies

Tet2 Deficiency in Macrophages Undermines Heart Repair after Infarction

Induced Transdifferentiation of Leukemia B-Cells to Macrophages Involves Reconfiguration of the DNA Methylome

Reciprocal Regulation of BCL6 and MLL Expression As a Vulnerability in MLL -Rearranged Acute Lymphoblastic Leukemia

Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation

Comprehensive Population-Based Genetic Fine Mapping and Single-Cell Epigenomics Provide Insights into the Regulation of Human Hematopoiesis

PDX Models Recapitulate Genetics and Epigenetics of Pediatric T-Cell Leukemia

Integrative Epigenomics Reveals Novel Chronic Lymphocytic Leukemia-Specific Chromatin States Associated with Epigenetic and Transcriptional Heterogeneity

Dot1l Reverses the Abnormal Self-Renewal Conferred on HSPCs through Cohesin Haploinsufficiency By Diminishing Expression of Hoxa7 and Hoxa9

Clinical Pharmacodynamic Markers and Combinations with SY1425 (tamibarotene) in a Genomically-Defined Subset of Non-APL AML

A Pharmacologically Reversible Epigenomic Signature of Relapse and Chemotherapy Resistance in Anaplastic Large Cell Lymphoma

Aging Human Hematopoietic Stem Cells Manifest Massive Epigenetic Reprogramming and Altered Gene Splicing of Key Hematopoietic Gene Sets

Polycomb-Dependent Epigenetic Landscape in Adult T Cell Leukemia (ATL); Providing Proof of Concept for Targeting EZH1/2 to Selectively Eliminate the HTLV-1 Infected Population

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American Society of Hematology

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American Society of Hematology

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