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Journal Articles

The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability

Zhaowei Tu, Chen Wang, Ashley K. Davis, Mengwen Hu, Chuntao Zhao, Mei Xin, Q. Richard Lu, Yi Zheng
Journal: Blood
Blood (2021) 138 (3): 221–233.
https://doi.org/10.1182/blood.2020009997
Published: 2021
Includes: Supplemental data
Journal Articles

Radiation-induced bystander effects impair transplanted human hematopoietic stem cells via oxidative DNA damage

Linping Hu, Xiuxiu Yin, Yawen Zhang, Aiming Pang, Xiaowei Xie, Shangda Yang, Caiying Zhu, Yapu Li, Biao Zhang, Yaojin Huang, Yunhong Tian, Mei Wang, Wenbin Cao, Shulian Chen, Yawei Zheng, Shihui Ma, Fang Dong, Sha Hao, Sizhou Feng, Yongxin Ru, Hui Cheng, Erlie Jiang, Tao Cheng
Journal: Blood
Blood (2021) 137 (24): 3339–3350.
https://doi.org/10.1182/blood.2020007362
Published: 2021
Includes: Supplemental data
Journal Articles

The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells

Lijian Shao, Adedamola Elujoba-Bridenstine, Katherine E. Zink, Laura M. Sanchez, Brian J. Cox, Karen E. Pollok, Anthony L. Sinn, Barbara J. Bailey, Emily C. Sims, Scott H. Cooper, Hal E. Broxmeyer, Kostandin V. Pajcini, Owen J. Tamplin
Journal: Blood
Blood (2021) 137 (6): 775–787.
https://doi.org/10.1182/blood.2019004415
Published: 2021
Includes: Supplemental data
Journal Articles

Sickle marrow: double, double toil and trouble

Mark C. Walters
Journal: Blood
Blood (2020) 135 (23): 2017–2018.
https://doi.org/10.1182/blood.2020005114
Published: 2020
Journal Articles

Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report

Clinical Trials & Observations
Lauri M. Burroughs, Aleksandra Petrovic, Ruta Brazauskas, Xuerong Liu, Linda M. Griffith, Hans D. Ochs, Jack J. Bleesing, Stephanie Edwards, Christopher C. Dvorak, Sonali Chaudhury, Susan E. Prockop, Ralph Quinones, Frederick D. Goldman, Troy C. Quigg, Shanmuganathan Chandrakasan, Angela R. Smith, Suhag Parikh, Blachy J. Dávila Saldaña, Monica S. Thakar, Rachel Phelan, Shalini Shenoy, Lisa R. Forbes, Caridad Martinez, Deepak Chellapandian, Evan Shereck, Holly K. Miller, Neena Kapoor, Jessie L. Barnum, Hey Chong, David C. Shyr, Karin Chen, Rolla Abu-Arja, Ami J. Shah, Katja G. Weinacht, Theodore B. Moore, Avni Joshi, Kenneth B. DeSantes, Alfred P. Gillio, Geoffrey D. E. Cuvelier, Michael D. Keller, Jacob Rozmus, Troy Torgerson, Michael A. Pulsipher, Elie Haddad, Kathleen E. Sullivan, Brent R. Logan, Donald B. Kohn, Jennifer M. Puck, Luigi D. Notarangelo, Sung-Yun Pai, David J. Rawlings, Morton J. Cowan
Journal: Blood
Blood (2020) 135 (23): 2094–2105.
https://doi.org/10.1182/blood.2019002939
Published: 2020
Journal Articles

Stem cell engraftment within our G(P)RASP

John P. Chute
Journal: Blood
Blood (2020) 135 (14): 1077–1078.
https://doi.org/10.1182/blood.2020005117
Published: 2020
Journal Articles

Engraftment in utero: it’s all in the delivery

Allistair A. Abraham, Dana Block-Abraham
Journal: Blood
Blood (2019) 134 (22): 1889–1890.
https://doi.org/10.1182/blood.2019003246
Published: 2019
Journal Articles

Donor cell engineering with GSK3 inhibitor–loaded nanoparticles enhances engraftment after in utero transplantation

Stavros P. Loukogeorgakis, Camila G. Fachin, Andre I. B. S. Dias, Haiying Li, Li Tang, Aimee G. Kim, Jesse D. Vrecenak, John D. Stratigis, Nicholas J. Ahn, Ilana Nissim, Izhtak Nissim, Antonio F. Moron, Jose L. Martins, William H. Peranteau, Paolo De Coppi, Darrell J. Irvine, Alan W. Flake
Journal: Blood
Blood (2019) 134 (22): 1983–1995.
https://doi.org/10.1182/blood.2019001037
Published: 2019
Includes: Supplemental data
Journal Articles

Whole-Genome CRISPR Screen Reveals the Mechanism of Relapse in Patient-Derived Cells Representing High-Risk Paediatric ALL

Katarzyna Szoltysek, PhD, Helen Blair, Sirintra Nakjang, Ricky Tirtakusuma, Mankaran Singh, Ryan Nelson, Hesta McNeill, Catherine Dodd, Melanie Beckett, Lynsey McKenzie, Edward Law, Josef Vormoor, MD PhD, Deepali Pal, Olaf Heidenreich
Journal: Blood
Blood (2019) 134 (Supplement_1): 3952.
https://doi.org/10.1182/blood-2019-124818
Published: 2019
Journal Articles

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Tracey Lodie, PhD, Julian Adams, PhD, Dima Yackoubov, Msc, Yair Steinhardt, MSc, Dorit Ashengrau, Adi Bitansky, Alina Maliutina, Sherry Cohen, Boaz Buhenvald, PhD, Moshe Shahor, PhD, Nathan Dinowitz, PhD, Vered Caspi, PhD, Amnon Peled, PhD, Tony Peled, MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3718.
https://doi.org/10.1182/blood-2019-131124
Published: 2019
Journal Articles

Robust Hematopoietic Stem Cell Function and Minimal Myeloid Skewing with Aging in Un-Separated Murine Whole Bone Marrow: What Are We Losing with Hematopoietic Stem Cell Purification?

Mark S Dooner, Elaine Papa, Michael Del Tatto, Mandy Pereira, Sicheng Wen, MD PhD, Yan Cheng, PhD, Peter J. Quesenberry, MD, Laura R Goldberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3723.
https://doi.org/10.1182/blood-2019-124367
Published: 2019
Journal Articles

IFNy Stimulation Induces Hematopoietic Stem Cell Homing and Niche Relocalization

Marcus A Florez, BS, Katie A Matatall, PhD, Laura Ortinau, PhD, Roman Jaksik, PhD, Marek Kimmel, PhD DSc, Dongsu Park, PhD, Katherine Y. King, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3726.
https://doi.org/10.1182/blood-2019-130555
Published: 2019
Journal Articles

Safety and Toxicity Profile of Pembrolizumab (PEM) in Combination with ICE Chemotherapy Followed By Autologous Stem Cell Transplantation for Relapsed/Refractory Classical Hodgkin Lymphoma: No Impairment in Stem Cell Mobilization or Engraftment

Locke J. Bryan, MD, Scott E. Smith, MD PhD, Pamela Allen, MDMSc, Carla Casulo, Brett Alan Palmer, BS, Reem Karmali, MD, Barbara Pro, MD, Denise M Scholtens, PhD, Hatice Savas, MD, Jayesh Mehta, MD, Leo I. Gordon, MD, Jane N. Winter, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4029.
https://doi.org/10.1182/blood-2019-123879
Published: 2019
Journal Articles

BrUOG 345: Fractionated Gemtuzumab Ozogamicin Followed By Non-Engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia

Adam Zayac, MD, Pamela C Egan, MD, Thomas A Ollila, MD, Adam J Olszewski, MD, Peter Barth, MD, Matthew I. Quesenberry, MD, James Butera, MD, Loren D. Fast, PhD, Rabin Niroula, MBBS, Peter J. Quesenberry, MD, John L Reagan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4460.
https://doi.org/10.1182/blood-2019-123789
Published: 2019
Journal Articles

CD9 Marks Flt3+ Multipotent Hematopoietic Progenitors within Lsk Cells

Fatemeh Safi, MSc, Ram Krishna Thakur, PhD, Parashar Dhapola, MSc, Eva Erlandsoon, Sarah Warsi, David Bryder, PhD, Charlotta Boiers, Göran Karlsson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2469.
https://doi.org/10.1182/blood-2019-126758
Published: 2019
Journal Articles

Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in AML

Sagarajit Mohanty, MSc, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Basem Othman, Arnold Kloos, PhD, Madhvi Mandhania, MSc, Renate Schottmann, Euan Ramsay, PhD, Hans- Peter Vornlocher, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2545.
https://doi.org/10.1182/blood-2019-123709
Published: 2019
Journal Articles

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Yamamoto Keita, MD, Susumu Goyama, MD PhD, Shuhei Asada, MD PhD, Takeshi Fujino, MD, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, MD, Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD, Reina Onoguchi, PhD, Nobuyoshi Akimitsu, PhD, Toshio Kitamura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2514.
https://doi.org/10.1182/blood-2019-125472
Published: 2019
Journal Articles

IPO11 Is Upregulated in Relapsed AML and Supports Survival of Leukemic Stem Cells

Boaz Nachmias, MD PhD, Veronique Voisin, PhD, Rose Hurren, BSc, Xioaming Wang, Neil Maclean, G. Wei Xu, Ayesh K Seneviratne, BSc, MSc, Changjiang Xu, Gary D Bader, Liran I. Shlush, MD, Aaron D Schimmer, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2530.
https://doi.org/10.1182/blood-2019-122284
Published: 2019
Journal Articles

Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy

Hye Na Kim, Enzi Jiang, MD PhD, Ruan Yongsheng, MD, Heather Ogana, Nour Abdel-Azim, Justin Le, BS, Annie Luong, Halvard Bonig, MD, Nabil Ahmed, MD, Moghimi Babak, MD, Michael A. Pulsipher, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Chintan Parekh, MBBS, Hisham Abdel-Azim, Nora Heisterkamp, Yong-Mi Kim, MD MPH, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2623.
https://doi.org/10.1182/blood-2019-132131
Published: 2019
Journal Articles

Use of Ex Vivo Graft Manipulation and Posttransplant Cyclophosphamide Result in Low GvHD Rates and Acceptable Engraftment after RIC Regimens in Pediatric Mismatched SCT

Peter Lang, MD, Michaela Döring, PD Dr. MD, Anne-Marie Lang, M.Sc., Patrick Schlegel, Dr. MD, Christian M. Seitz, Dr. MD, Robin Fischer, Dr. rer. nat., Ursula Holzer, PD Dr. MD, Ines Brecht, PD Dr. MD, Rupert Handgretinger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3255.
https://doi.org/10.1182/blood-2019-129654
Published: 2019