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Journal Articles

The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability

Zhaowei Tu, Chen Wang, Ashley K. Davis, Mengwen Hu, Chuntao Zhao, Mei Xin, Q. Richard Lu, Yi Zheng
Journal: Blood
Blood (2021) 138 (3): 221–233.
https://doi.org/10.1182/blood.2020009997
Published: 2021
Includes: Supplemental data
Journal Articles

Radiation-induced bystander effects impair transplanted human hematopoietic stem cells via oxidative DNA damage

Linping Hu, Xiuxiu Yin, Yawen Zhang, Aiming Pang, Xiaowei Xie, Shangda Yang, Caiying Zhu, Yapu Li, Biao Zhang, Yaojin Huang, Yunhong Tian, Mei Wang, Wenbin Cao, Shulian Chen, Yawei Zheng, Shihui Ma, Fang Dong, Sha Hao, Sizhou Feng, Yongxin Ru, Hui Cheng, Erlie Jiang, Tao Cheng
Journal: Blood
Blood (2021) 137 (24): 3339–3350.
https://doi.org/10.1182/blood.2020007362
Published: 2021
Includes: Supplemental data
Journal Articles

The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells

Lijian Shao, Adedamola Elujoba-Bridenstine, Katherine E. Zink, Laura M. Sanchez, Brian J. Cox, Karen E. Pollok, Anthony L. Sinn, Barbara J. Bailey, Emily C. Sims, Scott H. Cooper, Hal E. Broxmeyer, Kostandin V. Pajcini, Owen J. Tamplin
Journal: Blood
Blood (2021) 137 (6): 775–787.
https://doi.org/10.1182/blood.2019004415
Published: 2021
Includes: Supplemental data
Journal Articles

Sickle marrow: double, double toil and trouble

Mark C. Walters
Journal: Blood
Blood (2020) 135 (23): 2017–2018.
https://doi.org/10.1182/blood.2020005114
Published: 2020
Journal Articles

Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report

Clinical Trials & Observations
Lauri M. Burroughs, Aleksandra Petrovic, Ruta Brazauskas, Xuerong Liu, Linda M. Griffith, Hans D. Ochs, Jack J. Bleesing, Stephanie Edwards, Christopher C. Dvorak, Sonali Chaudhury, Susan E. Prockop, Ralph Quinones, Frederick D. Goldman, Troy C. Quigg, Shanmuganathan Chandrakasan, Angela R. Smith, Suhag Parikh, Blachy J. Dávila Saldaña, Monica S. Thakar, Rachel Phelan, Shalini Shenoy, Lisa R. Forbes, Caridad Martinez, Deepak Chellapandian, Evan Shereck, Holly K. Miller, Neena Kapoor, Jessie L. Barnum, Hey Chong, David C. Shyr, Karin Chen, Rolla Abu-Arja, Ami J. Shah, Katja G. Weinacht, Theodore B. Moore, Avni Joshi, Kenneth B. DeSantes, Alfred P. Gillio, Geoffrey D. E. Cuvelier, Michael D. Keller, Jacob Rozmus, Troy Torgerson, Michael A. Pulsipher, Elie Haddad, Kathleen E. Sullivan, Brent R. Logan, Donald B. Kohn, Jennifer M. Puck, Luigi D. Notarangelo, Sung-Yun Pai, David J. Rawlings, Morton J. Cowan
Journal: Blood
Blood (2020) 135 (23): 2094–2105.
https://doi.org/10.1182/blood.2019002939
Published: 2020
Journal Articles

Stem cell engraftment within our G(P)RASP

John P. Chute
Journal: Blood
Blood (2020) 135 (14): 1077–1078.
https://doi.org/10.1182/blood.2020005117
Published: 2020
Journal Articles

Donor cell engineering with GSK3 inhibitor–loaded nanoparticles enhances engraftment after in utero transplantation

Stavros P. Loukogeorgakis, Camila G. Fachin, Andre I. B. S. Dias, Haiying Li, Li Tang, Aimee G. Kim, Jesse D. Vrecenak, John D. Stratigis, Nicholas J. Ahn, Ilana Nissim, Izhtak Nissim, Antonio F. Moron, Jose L. Martins, William H. Peranteau, Paolo De Coppi, Darrell J. Irvine, Alan W. Flake
Journal: Blood
Blood (2019) 134 (22): 1983–1995.
https://doi.org/10.1182/blood.2019001037
Published: 2019
Includes: Supplemental data
Journal Articles

Engraftment in utero: it’s all in the delivery

Allistair A. Abraham, Dana Block-Abraham
Journal: Blood
Blood (2019) 134 (22): 1889–1890.
https://doi.org/10.1182/blood.2019003246
Published: 2019
Journal Articles

Whole-Genome CRISPR Screen Reveals the Mechanism of Relapse in Patient-Derived Cells Representing High-Risk Paediatric ALL

Katarzyna Szoltysek, PhD, Helen Blair, Sirintra Nakjang, Ricky Tirtakusuma, Mankaran Singh, Ryan Nelson, Hesta McNeill, Catherine Dodd, Melanie Beckett, Lynsey McKenzie, Edward Law, Josef Vormoor, MD PhD, Deepali Pal, Olaf Heidenreich
Journal: Blood
Blood (2019) 134 (Supplement_1): 3952.
https://doi.org/10.1182/blood-2019-124818
Published: 2019
Journal Articles

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Tracey Lodie, PhD, Julian Adams, PhD, Dima Yackoubov, Msc, Yair Steinhardt, MSc, Dorit Ashengrau, Adi Bitansky, Alina Maliutina, Sherry Cohen, Boaz Buhenvald, PhD, Moshe Shahor, PhD, Nathan Dinowitz, PhD, Vered Caspi, PhD, Amnon Peled, PhD, Tony Peled, MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3718.
https://doi.org/10.1182/blood-2019-131124
Published: 2019
Journal Articles

Mitochondrial Activity Identifies a Transcriptionally and Functionally Distinct Subset of Aged HSCs with Lineage-Balanced Output

Els Mansell, PhD, Valgardur Sigurdsson, PhD, Elitza Deltcheva, PhD, John Brown, PhD, Chela James, PhD, Kenichi Miharada, PhD, Shamit Soneji, PhD, Jonas Larsson, MD PhD, Tariq Enver, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2480.
https://doi.org/10.1182/blood-2019-124001
Published: 2019
Journal Articles

Administration of Plerixafor in Poor Mobilizers Allows Mobilization of Haematopoietic Progenitors: Clonogenic Potential and Engraftment Analysis

Laura Pezzetti, MSc, Giambattista Bertani, MD, Liliana Intropido, MSc, Tiziana Lamacchia, MSc, Mariateresa Pugliano, MD, Elisabetta Bice Volpato, MD, Elisa Zucchetti, MD, Giovanni Grillo, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5633.
https://doi.org/10.1182/blood-2019-125055
Published: 2019
Journal Articles

Impact of Pre-Engraftment Cytomegalovirus Viraemia in Allogeneic Haematopoetic Stem Cell Transplant Recipients

Joanne L C Tan, MBBS, Shio Yen Tio, MBBS, FRACP, Michelle K Yong, MBBS, FRACP, MPH, PhD, David Ritchie, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5656.
https://doi.org/10.1182/blood-2019-122368
Published: 2019
Journal Articles

Pentotstatin/TBI Conditioning Is Well-Tolerated and Permits Engraftment of a Second Allogeneic Stem Cell Transplant Following Primary or Secondary Rejection of an Allogeneic Hematopoietic Stem Graft

Ani Gvajaia, MD, Amelia Langston, MD, Natia Esiashvil, MD, Michael Graiser, PhD, Kelly Valla, PharmD, Edmund K. Waller, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5657.
https://doi.org/10.1182/blood-2019-122467
Published: 2019
Journal Articles

Re-Induction and Targeted Conditioning with Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] Leads to High Rates of Transplantation and Successful Engraftment in Older Patients with Active, Relapsed or Refractory (rel/ref) AML after Failure of Chemotherapy and Targeted Agents: Preliminary Midpoint Results from the Prospective, Randomized Phase 3 Sierra Trial

Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Patrick J. Stiff, MD, Edward Agura, MD, Mark Litzow, MD, Ben Tomlinson, MD, Hannah K. Choe, MD, Sunil Abhyankar, MD, Stuart Seropian, MD, George L. Chen, MD, Parameswaran Hari, MBBS, MD, Zaid S. Al-Kadhimi, MD, James M. Foran, MD, Johnnie Orozco, MD, Koen Van Besien, MD PhD, Mitchell Sabloff, MD, Partow Kebriaei, MD, Moshe Yair Levy, MD, Hillard M Lazarus, MD, Sergio A Giralt, MD, Mark S. Berger, MD, Vijay Reddy, MD PhD, John M. Pagel, MD PhD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 5642.
https://doi.org/10.1182/blood-2019-122776
Published: 2019
Journal Articles

Better Engraftment of Single-Unit Unrelated Cord Blood Transplantation in Patients with Acquired Severe Aplastic Anemia Not Respond to IST Using Conditioning Regimen without ATG

Wan Xiang, MD PhD, Baolin Tang, Huilan Liu, Xiaoyu Zhu, Kaidi Song, Wen Yao, Xuhan Zhang, Guangyu Sun, Zimin Sun
Journal: Blood
Blood (2019) 134 (Supplement_1): 5727.
https://doi.org/10.1182/blood-2019-130198
Published: 2019
Journal Articles

CD9 Marks Flt3+ Multipotent Hematopoietic Progenitors within Lsk Cells

Fatemeh Safi, MSc, Ram Krishna Thakur, PhD, Parashar Dhapola, MSc, Eva Erlandsoon, Sarah Warsi, David Bryder, PhD, Charlotta Boiers, Göran Karlsson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2469.
https://doi.org/10.1182/blood-2019-126758
Published: 2019
Journal Articles

Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in AML

Sagarajit Mohanty, MSc, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Basem Othman, Arnold Kloos, PhD, Madhvi Mandhania, MSc, Renate Schottmann, Euan Ramsay, PhD, Hans- Peter Vornlocher, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2545.
https://doi.org/10.1182/blood-2019-123709
Published: 2019
Journal Articles

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Yamamoto Keita, MD, Susumu Goyama, MD PhD, Shuhei Asada, MD PhD, Takeshi Fujino, MD, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, MD, Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD, Reina Onoguchi, PhD, Nobuyoshi Akimitsu, PhD, Toshio Kitamura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2514.
https://doi.org/10.1182/blood-2019-125472
Published: 2019
Journal Articles

IPO11 Is Upregulated in Relapsed AML and Supports Survival of Leukemic Stem Cells

Boaz Nachmias, MD PhD, Veronique Voisin, PhD, Rose Hurren, BSc, Xioaming Wang, Neil Maclean, G. Wei Xu, Ayesh K Seneviratne, BSc, MSc, Changjiang Xu, Gary D Bader, Liran I. Shlush, MD, Aaron D Schimmer, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2530.
https://doi.org/10.1182/blood-2019-122284
Published: 2019