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Journal Articles

Synthetic Lethality-Based Approach Identified EED and BRD4 As Critical Survival Factorsin Acte Myeloid Leukemia with Monosomy 7

Kensuke Matsuda, MD, Yuki Kagoya, MD PhD, Sho Yamazaki, MD PhD, Masashi Miyauchi, MD PhD, Mineo Kurokawa, MD PhD

Blood (2019) 134 (Supplement_1): 1233.

https://doi.org/10.1182/blood-2019-123595

Published: 2019

Journal Articles

Role of Genetic Evolution and Germline Mutations in SAMD9 and SAMD9L Genes

Jason R Schwartz, MD PhD, Marcin W. Wlodarski, MD PhD, Jeffery M. Klco, MD PhD

Blood (2019) 134 (Supplement_1): SCI-33.

https://doi.org/10.1182/blood-2019-121042

Published: 2019

Journal Articles

Biology of Acute Myeloid Leukemia (AML) with Monosomy of Chromosome 7 or Loss of 7q. a Study on 487 Patients Analyzed By Gene Expression Profile (GEP), Single Nucleotide Polymorphism (SNP) Arrays and Metabolomics

Blood (2018) 132 (Supplement 1): 2748.

https://doi.org/10.1182/blood-2018-99-118183

Published: 2018

Journal Articles

The enigma of monosomy 7

Toshiya Inaba, Hiroaki Honda, Hirotaka Matsui

Blood (2018) 131 (26): 2891–2898.

https://doi.org/10.1182/blood-2017-12-822262

Published: 2018

Journal Articles

Puzzling pieces of chromosome 7 loss or deletion

Rebekka K. Schneider, Ruud Delwel

Blood (2018) 131 (26): 2871–2872.

https://doi.org/10.1182/blood-2018-04-844746

Published: 2018

Journal Articles

Mutational Pattern and Clonal Hierarchy in MDS with Monosomy 7

Claudia Haferlach, MD, Wencke Walter, PhD, Anna Stengel, PhD, Niroshan Nadarajah, Wolfgang Kern, MD, Manja Meggendorfer, PhD, Torsten Haferlach, MD

Blood (2017) 130 (Supplement 1): 2962.

https://doi.org/10.1182/blood.V130.Suppl_1.2962.2962

Published: 2017

Journal Articles

Constitutional SAMD9L Mutations Cause Familial Myelodisplastic Syndrome with Monosomy 7 and Stable Revertant Mosaicism

Blood (2017) 130 (Supplement 1): 1672.

https://doi.org/10.1182/blood.V130.Suppl_1.1672.1672

Published: 2017

Journal Articles

Preferential In Vitro and In Vivo Induction of Endogenous Retrovirus Transcription from a Monoallelic Chromosome 7q in Decitabine (DAC) Treated AML Blasts

Gabriele Greve, Dietmar Pfeifer, Sina Bengel, Michael Lübbert

Blood (2017) 130 (Supplement 1): 2612.

https://doi.org/10.1182/blood.V130.Suppl_1.2612.2612

Published: 2017

Journal Articles

Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms

Blood (2017) 129 (16): 2266–2279.

https://doi.org/10.1182/blood-2016-10-743302

Published: 2017

Includes: Supplemental data

Journal Articles

The Use of Hypomethylating Agents (HMAs) in Patients with Relapsed and Refractory Acute Myeloid Leukemia (RR-AML): Clinical Outcomes and Their Predictors in a Large International Patient Cohort

Blood (2016) 128 (22): 1063.

https://doi.org/10.1182/blood.V128.22.1063.1063

Published: 2016

Journal Articles

Survival Improvement in Therapy Related Myeloid Neosplasm ? a Single Center Analysis of 428 Patients

Khalil Saleh, MD, Christophe Willekens, MD, Jean Edouard Martin, Myriam Kossai, Nadine Khalifé-Saleh, MD, Véronique Saada, PharmD, Nathalie Auger, Alina Danu, MD, Julien Lazarovici, MD, Alexandra Leary, Suzette Delaloge, Jean Henri Bourhis, MD PhD, Éric Solary, MD PhD, Serge Koscielny, Stephane de Botton, Jean-Baptiste Micol, MD PhD

Blood (2016) 128 (22): 4006.

https://doi.org/10.1182/blood.V128.22.4006.4006

Published: 2016

Journal Articles

Late Clonal Disorders in Patients with Aplastic Anemia

Alina Kokhno, MD, PhD, Elena A Mikhaylova, MD PhD Prof, Zalina T. Fidarova, Elena Ustinova, MD PhD, Vera V. Troitskaya, MD PhD, Andrey N. Sokolov, MD PhD, Larisa P. Mendeleeva, MD PhD, Larisa A. Kuzmina, MD PhD, Nina V. Tsvetaeva, MD PhD, Valentina N. Dvirnyk, MD, PhD, Tatiana N. Obukhova, PhD, Alla M. Kovrigina, MD PhD Prof., Elena N. Parovichnikova, MD PhD, Valeri Savchenko, MD PhD Prof.

Blood (2015) 126 (23): 4787.

https://doi.org/10.1182/blood.V126.23.4787.4787

Published: 2015

Journal Articles

Impact of Somatic Mutations on Outcome in Patients with MDS after Stem-Cell Transplantation

Tetsuichi Yoshizato, MD, Yusuke Shiozawa, MD, Kenichi Yoshida, MD PhD, Yoshiko Atsuta, MDPhD, Chika Ito, Keisuke Kataoka, MD PhD, Makoto Onizuka, MD PhD, Hiromichi Suzuki, MD PhD, Kenichi Chiba, BA, Hiroko Tanaka, BA, Yuichi Shiraishi, MD PhD, Yasunobu Nagata, MDPhD, Masashi Sanada, MD PhD, Hidehiro Itonaga, MD PhD, Yoshinobu Kanda, MD PhD, Yasushi Miyazaki, MD, Hideki Makishima, MD PhD, Satoru Miyano, MD PhD, Seishi Ogawa, MD PhD

Blood (2015) 126 (23): 711.

https://doi.org/10.1182/blood.V126.23.711.711

Published: 2015

Journal Articles

Clinical Outcome of Hypomethylating Agents in Hypocellular MDS: Mayo Clinic Experience

Sonia Cerquozzi, MD, Hassan B Alkhateeb, MD, Moritz Binder, MD MPH, Darci Zblewski, CNP, Shahrukh K Hashmi, MD, Mrinal M Patnaik, MBBS, William J. Hogan, MBChB, Mark R. Litzow, MD, Aref Al-Kali, MD

Blood (2015) 126 (23): 5254.

https://doi.org/10.1182/blood.V126.23.5254.5254

Published: 2015

Journal Articles

Mutations in CALR Are Associated with Del(13q) and Are Mutually Exclusive of Monosomy 7 in BCR-ABL1 -Negative MPN

Sabine Jeromin, PhD, Claudia Haferlach, MD, Manja Meggendorfer, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD, Susanne Schnittger, PhD

Blood (2014) 124 (21): 1870.

https://doi.org/10.1182/blood.V124.21.1870.1870

Published: 2014

Journal Articles

Multi-Center Study on Myelodysplastic Syndromes with Isolated Partial or Total Loss of Chromosome 7

Elena Crisà, MD, Esperanza Such, PhD, Steven Best, PhD, Austin Kulasekararaj, José Cervera, Vera Adema, PhDstudent, Nicholas Lea, PhD, Dario Ferrero, MD PhD, Bernardino Allione, Julie Schanz, MD PhD, Detlef Haase, MD, Guillermo F. Sanz, MD PhD, Francesco Sole, PhD, Ghulam J. Mufti, MD PhD

Blood (2014) 124 (21): 4662.

https://doi.org/10.1182/blood.V124.21.4662.4662

Published: 2014

Journal Articles

Association Between Downregulation of POT1 Expression and Chromosome 7 Deletion, Response to Hypomethylation Agent Treatment, and Patient Survival in Myelodysplastic Syndromes

Yue Wei, Amit Verma, MD, Monica Cabrero, MD, Yu Jia, Hong Zheng, Zhihong Fang, Yiting Yu, PhD, Simona Colla, Zach Bohannan, Teresa V. Bowman, PhD, Jacqueline Boultwood, PhD, Guillermo Garcia-Manero, MD

Blood (2014) 124 (21): 4663.

https://doi.org/10.1182/blood.V124.21.4663.4663

Published: 2014

Journal Articles

Down-Regulated Expression Of Protection Of Telomeres 1 (POT1) Gene In Bone Marrow Hematopoietic Progenitor Cell Compartment Has Prognostic Value In Myelodysplastic Syndromes (MDS)

Yue Wei, PhD, Yu Jia, Hong Zheng, Hui Yang, M.D., Ph.D., Zhihong Fang, Simona Colla, PhD, Guillermo Garcia-Manero, MD

Blood (2013) 122 (21): 1511.

https://doi.org/10.1182/blood.V122.21.1511.1511

Published: 2013

Journal Articles

Somatic Mutations and Loss-Of-Heterozygosity Impair The DNA Repair Functions Of CUX1 in Myelodysplastic Syndromes (MDS)

Naoko Hosono, MD, PhD, Zubaidah M Ramdzan, PhD, Ranjana Pal, PhD, Hideki Makishima, MD, PhD, Bartlomiej P Przychodzen, PhD, Mikkael A. Sekeres, MD, MS, Kenichi Yoshida, MD, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Seishi Ogawa, MD, PhD, Alain Nepveu, PhD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2013) 122 (21): 1246.

https://doi.org/10.1182/blood.V122.21.1246.1246

Published: 2013

Journal Articles

Novel Function Of Chromosome 7 Open Reading Frame 41 Gene To Promote Leukemic Megakaryocyte Differentiation By Modulating TPA-Induced MAPK/ERK, SAPK/JNK, and NF-κB Signaling

Xueqin Sun, Bin Lu, Zan Huang

Blood (2013) 122 (21): 1209.

https://doi.org/10.1182/blood.V122.21.1209.1209

Published: 2013

NARROW

Synthetic Lethality-Based Approach Identified EED and BRD4 As Critical Survival Factorsin Acte Myeloid Leukemia with Monosomy 7

Role of Genetic Evolution and Germline Mutations in SAMD9 and SAMD9L Genes

Biology of Acute Myeloid Leukemia (AML) with Monosomy of Chromosome 7 or Loss of 7q. a Study on 487 Patients Analyzed By Gene Expression Profile (GEP), Single Nucleotide Polymorphism (SNP) Arrays and Metabolomics

The enigma of monosomy 7

Puzzling pieces of chromosome 7 loss or deletion

Mutational Pattern and Clonal Hierarchy in MDS with Monosomy 7

Constitutional SAMD9L Mutations Cause Familial Myelodisplastic Syndrome with Monosomy 7 and Stable Revertant Mosaicism

Preferential In Vitro and In Vivo Induction of Endogenous Retrovirus Transcription from a Monoallelic Chromosome 7q in Decitabine (DAC) Treated AML Blasts

Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms

The Use of Hypomethylating Agents (HMAs) in Patients with Relapsed and Refractory Acute Myeloid Leukemia (RR-AML): Clinical Outcomes and Their Predictors in a Large International Patient Cohort

Survival Improvement in Therapy Related Myeloid Neosplasm ? a Single Center Analysis of 428 Patients

Late Clonal Disorders in Patients with Aplastic Anemia

Impact of Somatic Mutations on Outcome in Patients with MDS after Stem-Cell Transplantation

Clinical Outcome of Hypomethylating Agents in Hypocellular MDS: Mayo Clinic Experience

Mutations in CALR Are Associated with Del(13q) and Are Mutually Exclusive of Monosomy 7 in BCR-ABL1 -Negative MPN

Multi-Center Study on Myelodysplastic Syndromes with Isolated Partial or Total Loss of Chromosome 7

Association Between Downregulation of POT1 Expression and Chromosome 7 Deletion, Response to Hypomethylation Agent Treatment, and Patient Survival in Myelodysplastic Syndromes

Down-Regulated Expression Of Protection Of Telomeres 1 (POT1) Gene In Bone Marrow Hematopoietic Progenitor Cell Compartment Has Prognostic Value In Myelodysplastic Syndromes (MDS)

Somatic Mutations and Loss-Of-Heterozygosity Impair The DNA Repair Functions Of CUX1 in Myelodysplastic Syndromes (MDS)

Novel Function Of Chromosome 7 Open Reading Frame 41 Gene To Promote Leukemic Megakaryocyte Differentiation By Modulating TPA-Induced MAPK/ERK, SAPK/JNK, and NF-κB Signaling

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American Society of Hematology

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American Society of Hematology

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