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Journal Articles

Targeting the plasticity of mesenchymal stromal cells to reroute the course of acute myeloid leukemia

Blood (2021) 138 (7): 557–570.

https://doi.org/10.1182/blood.2020009845

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin

Christopher Hoover, Yuji Kondo, Bojing Shao, Michael J. McDaniel, Robert Lee, Samuel McGee, Sidney Whiteheart, Wolfgang Bergmeier, Rodger P. McEver, Lijun Xia

Blood (2021) 137 (20): 2756–2769.

https://doi.org/10.1182/blood.2020010310

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Talin-1 is the principal platelet Rap1 effector of integrin activation

Frederic Lagarrigue, David S. Paul, Alexandre R. Gingras, Andrew J. Valadez, Hao Sun, Jenny Lin, Monica N. Cuevas, Jailal N. Ablack, Miguel Alejandro Lopez-Ramirez, Wolfgang Bergmeier, Mark H. Ginsberg

Blood (2020) 136 (10): 1180–1190.

https://doi.org/10.1182/blood.2020005348

Published: 2020

Includes: Supplemental data

Journal Articles

Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum

Juthakorn Poothong, Anita Pottekat, Marina Siirin, Alexandre Rosa Campos, Adrienne W. Paton, James C. Paton, Jacqueline Lagunas-Acosta, Zhouji Chen, Mark Swift, Niels Volkmann, Dorit Hanein, Jing Yong, Randal J. Kaufman

Blood (2020) 135 (21): 1899–1911.

https://doi.org/10.1182/blood.2019002867

Published: 2020

Includes: Supplemental data

Journal Articles

Myeloma Derived Extracellular Vesicles Containing Endoplasmic Reticulum Remodel the Bone Marrow Microenvironment Towards a Pro-Tumoral Senescent Phenotype

Yu Sun, BSc, MSc, PhD, Jayna J Mistry, BSc, Jamie A Moore, BSc, MSc, Charlotte Hellmich, MBBChir, Christopher R Marlein, PhD, Anna Haestier, Cesar A. Gomez, MD PhD FRCPath, Christopher J Morris, PhD, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD

Blood (2019) 134 (Supplement_1): 689.

https://doi.org/10.1182/blood-2019-128268

Published: 2019

Journal Articles

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

Wen Zhu, Yongwei Zheng, PhD, Mei Yu, PhD, Yaling Wu, Jianhui Wei, Nicholas Schneider, Anand Padmanabhan, MD PhD, Richard H. Aster, MD, Demin Wang, PhD, Renren Wen, PhD

Blood (2019) 134 (Supplement_1): 439.

https://doi.org/10.1182/blood-2019-126097

Published: 2019

Journal Articles

Proof of Concept for Tipifarnib in Relapsed or Refractory Angioimmunoblastic T-Cell Lymphoma (AITL) and CXCL12+ Peripheral T-Cell Lymphoma (PTCL): Preliminary Results from an Open-Label, Phase 2 Study

Blood (2019) 134 (Supplement_1): 468.

https://doi.org/10.1182/blood-2019-128513

Published: 2019

Journal Articles

Extensive Metabolic Correction of Hurler Disease By Hematopoietic Stem Cell-Based Gene Therapy: Preliminary Results from a Phase I/II Trial

Bernhard Gentner, MD, Maria Ester Bernardo, MD PhD, Francesca Tucci, MD, Erika Zonari, PhD, Francesca Fumagalli, MD, Silvia Pontesilli, MD, Serena Acquati, PhD, Paolo Silvani, MD, Fabio Ciceri, MD, Attilio Rovelli, MD, Giancarlo La Marca, PhD, Rossella Parini, MD, Silvia Gregori, PhD, Eugenio Montini, PhD, Luigi Naldini, MD PhD, Alessandro Aiuti, MD PhD

Blood (2019) 134 (Supplement_1): 607.

https://doi.org/10.1182/blood-2019-128805

Published: 2019

Journal Articles

IL-33 Therapy Prevents Acute Lung Injury after Transplantation Via IL-9-Producing Type 2 Innate Lymphoid Cells Induction

Hua Jiang, PhD, Abdulraouf Ramadan, PhD, Becquet Laurine, MS, Tu Szu-Wei, Hong Liu, MS, Courtney Rowan, MD, Xiaowen Liu, PhD, Huanmei Wu, PhD, Jun Wan, PhD, Sophie Paczesny, MD PhD

Blood (2019) 134 (Supplement_1): 583.

https://doi.org/10.1182/blood-2019-123821

Published: 2019

Journal Articles

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Lorenzo Iovino, MD, Paul DeRoos, Reema Jain, PhD, Jarrod A Dudakov, PhD

Blood (2019) 134 (Supplement_1): 587.

https://doi.org/10.1182/blood-2019-131513

Published: 2019

Journal Articles

Double-Blind, Randomized Study of Canakinumab Treatment in Pediatric and Young Adult Patients with Sickle Cell Anemia

Blood (2019) 134 (Supplement_1): 615.

https://doi.org/10.1182/blood-2019-123355

Published: 2019

Journal Articles

Thymus Regeneration Is Dependent on Distinct Mesenchymal Stromal Cell Populations

Karin Gustafsson, PhD, Nikolas Barkas, PhD, Ninib Baryawno, PhD, Elizabeth W Scadden, Nicolas Severe, PhD, Joel A Spencer, PhD, Hayalneh Gessessew, Kameron Kooshesh, Jimin Guo, PhD, Charles Lin, PhD, Peter Kharchenko, PhD, David T. Scadden, MD

Blood (2019) 134 (Supplement_1): 586.

https://doi.org/10.1182/blood-2019-126708

Published: 2019

Journal Articles

RNA Sequencing of Hodgkin Lymphoma Reed-Sternberg Cells Uncovers a Plasma Cell Signature and Escape from NK Cell Recognition

Ethel Cesarman, MD PhD, Mikhail Roshal, MD PhD, Jonathan Reichel, PhD, Wagner Florian, PhD, Bhavneet Binder, Sakellarios Zairis, Jouliana Sadek, PhD, Joshua Brody, MD, Raul Rabadan, PhD, Sandeep Dave, MD

Blood (2019) 134 (Supplement_1): 549.

https://doi.org/10.1182/blood-2019-131163

Published: 2019

Journal Articles

The Infection-Driven Production/Secretion of Inflammatory Cytokines By Circulating Monocytes of Myelofibrosis Is Defective and Is Reactivated after In Vivo JAK1/2 Inhibition

Martina Barone, PhD, Francesca Ricci, BS, Marco Romano, PhD, Dorian Forte, PhD, Giuseppe Auteri, MD, Francesco Fabbri, PhD, Emanuela Ottaviani, Pierluigi Tazzari, MD, Nicola Vianelli, MD, Giovanni Martinelli, MD, Michele Cavo, Francesca Palandri, PhD MD, Lucia Catani

Blood (2019) 134 (Supplement_1): 1686.

https://doi.org/10.1182/blood-2019-127322

Published: 2019

Journal Articles

Dynamic and Time-to-Event Analyses Demonstrate Marked Reduction in Transfusion Requirements for Janus Kinase Inhibitor-Naïve Myelofibrosis Patients Treated with Momelotinib Compared Head to Head with Ruxolitinib

Ruben A Mesa, MD, John Catalano, MBBS, FRACP, FRCPA, Francisco Cervantes, MD, Timothy Devos, MD PhD, Jason Gotlib, MD MS, Jean-Jacques Kiladjian, MD PhD, Donal P. McLornan, MB, BCh (Hons), MRCP, PhD FRCPath, Kazuya Shimoda, MD PhD, Elisabeth Coart, PhD, Koenraad D'Hollander, MD MSC, Rafe Donahue, PhD, Mark M Kowalski, MD PhD

Blood (2019) 134 (Supplement_1): 1663.

https://doi.org/10.1182/blood-2019-122506

Published: 2019

Journal Articles

TNB383B.0001: A Multicenter, Phase 1, Open-Label, Dose-Escalation Andexpansion Study of TNB-383B, a Bispecific Antibodytargeting BCMA in Subjects with Relapsed or Refractorymultiple Myeloma

Ben Buelow, MD PhD, Anita D'Souza, MBBS, Cesar Rodriguez, MD, Ravi Vij, MBBS, Rajneesh Nath, MD, Melinda Snyder, MS, Duy Pham, MBA, Ashwin Patel, PhD, Suhasini Iyer, PhD

Blood (2019) 134 (Supplement_1): 1874.

https://doi.org/10.1182/blood-2019-123220

Published: 2019

Journal Articles

Erythroferrone Regulates Bone Remodeling in β-Thalassemia

Melanie Castro-Mollo, MD, Marc Ruiz Martinez, PhD, Maria Feola, PhD, Anisa Azatovna Gumerova, MD, Carla Casu, PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Tony Yuen, PhD, Mone Zaidi, MD PhD, Yelena Ginzburg, MD

Blood (2019) 134 (Supplement_1): 2.

https://doi.org/10.1182/blood-2019-125822

Published: 2019

Journal Articles

Clearance of Vector DNA Following Systemic Administration of AAV5-hFIX or AAV5-hFIX Padua in Patients with Severe or Moderate-Severe Hemophilia B

Eileen K Sawyer, PhD, Sander Gielen, PhD, Jaap Twisk, Alison Long, Robert Gut

Blood (2019) 134 (Supplement_1): 2062.

https://doi.org/10.1182/blood-2019-129786

Published: 2019

Journal Articles

VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex

Anish V. Sharda, MBBS, MPH, Joshua Harrison, BS, Adrian R. Wilkie, PhD, Chao Fang, PhD, Lourdes M. Mendez, MD PhD, Joseph E. Italiano, Jr., BS, PhD, Robert C. Flaumenhaft, MD PhD

Blood (2019) 134 (Supplement_1): 8.

https://doi.org/10.1182/blood-2019-127712

Published: 2019

Journal Articles

Development of an Allogeneic Anti-Bcma T Cell Therapy Utilizing a Novel Dimeric Antigen Receptor (DAR) Structure

Bei Bei Ding, PhD, John Dixon Gray, PhD, Nan Zhang, Yanliang Zhang, PhD, Xia Cao, MSc, Irina Krapf, MSc, Qingdong Mark Deng, Angel Wei, MD, Jerome B. Zeldis, MD PhD, Robert D. Knight, MD, Gunnar F. Kaufmann, PhD, Henry Ji, PhD, Wenzhong Guo, PhD

Blood (2019) 134 (Supplement_1): 1942.

https://doi.org/10.1182/blood-2019-131892

Published: 2019

NARROW

Targeting the plasticity of mesenchymal stromal cells to reroute the course of acute myeloid leukemia

Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin

Talin-1 is the principal platelet Rap1 effector of integrin activation

Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum

Myeloma Derived Extracellular Vesicles Containing Endoplasmic Reticulum Remodel the Bone Marrow Microenvironment Towards a Pro-Tumoral Senescent Phenotype

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

Proof of Concept for Tipifarnib in Relapsed or Refractory Angioimmunoblastic T-Cell Lymphoma (AITL) and CXCL12+ Peripheral T-Cell Lymphoma (PTCL): Preliminary Results from an Open-Label, Phase 2 Study

Extensive Metabolic Correction of Hurler Disease By Hematopoietic Stem Cell-Based Gene Therapy: Preliminary Results from a Phase I/II Trial

IL-33 Therapy Prevents Acute Lung Injury after Transplantation Via IL-9-Producing Type 2 Innate Lymphoid Cells Induction

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

Double-Blind, Randomized Study of Canakinumab Treatment in Pediatric and Young Adult Patients with Sickle Cell Anemia

Thymus Regeneration Is Dependent on Distinct Mesenchymal Stromal Cell Populations

RNA Sequencing of Hodgkin Lymphoma Reed-Sternberg Cells Uncovers a Plasma Cell Signature and Escape from NK Cell Recognition

The Infection-Driven Production/Secretion of Inflammatory Cytokines By Circulating Monocytes of Myelofibrosis Is Defective and Is Reactivated after In Vivo JAK1/2 Inhibition

Dynamic and Time-to-Event Analyses Demonstrate Marked Reduction in Transfusion Requirements for Janus Kinase Inhibitor-Naïve Myelofibrosis Patients Treated with Momelotinib Compared Head to Head with Ruxolitinib

TNB383B.0001: A Multicenter, Phase 1, Open-Label, Dose-Escalation Andexpansion Study of TNB-383B, a Bispecific Antibodytargeting BCMA in Subjects with Relapsed or Refractorymultiple Myeloma

Erythroferrone Regulates Bone Remodeling in β-Thalassemia

Clearance of Vector DNA Following Systemic Administration of AAV5-hFIX or AAV5-hFIX Padua in Patients with Severe or Moderate-Severe Hemophilia B

VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex

Development of an Allogeneic Anti-Bcma T Cell Therapy Utilizing a Novel Dimeric Antigen Receptor (DAR) Structure

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American Society of Hematology

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American Society of Hematology

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