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Journal Articles

CEBPA bZip mutations: just a single shot

Jorge Sierra, Josep F. Nomdedeu
Journal: Blood
Blood (2021) 138 (13): 1091–1092.
https://doi.org/10.1182/blood.2021011263
Published: 2021
Journal Articles

Genetic Activation of NRF2 By KEAP1 Inhibition Induces Fetal Hemoglobin Expression and Triggers Anti-Oxidant Stress Response in Erythroid Cells

Dipti Gupta, Samuel Lessard, PhD, Nancy Moore, Jicheng Duan, PhD, Yukio Nakamura, MD PhD, Feng-Chun Yang, MD PhD, Alexandra Hicks, PhD, David R. Light, PhD, Sriram Krishnamoorthy, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 210.
https://doi.org/10.1182/blood-2019-129479
Published: 2019
Journal Articles

Somatic Bzip Mutations of CEBPA Are Associated with Favorable Outcome Regardless of Presence As Single Vs. Double Mutation

Katherine Tarlock, MD, Todd A. Alonzo, PhD, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, MA, Tiffany A. Hylkema, BS, William G. Woods, MD, Todd M Cooper, DO, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 181.
https://doi.org/10.1182/blood-2019-126273
Published: 2019
Journal Articles

CEBPA Gene Mutations Interfere with Expressions of NKG2D Ligands Ulbps in AML Cells and Modulate Their Susceptibility to NK-Mediated Lysis

Meng Liu, Limengmeng Wang, PhD, Huafang Wang, Shan Fu, He Huang, Haowen Xiao
Journal: Blood
Blood (2019) 134 (Supplement_1): 1257.
https://doi.org/10.1182/blood-2019-129899
Published: 2019
Journal Articles

HTLV-1 Dysregulates IL-6 and IL-10-JAK/STAT Signaling and Induces Leukemia/Lymphoma of Mature CD4+ T Cells with Regulatory T-Cell-like Signatures

Yusuke Higuchi, MD, Jun-ichirou Yasunaga, MD PhD, Yu Mitagami, PhD, Koichi Ohshima, MD PhD, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1516.
https://doi.org/10.1182/blood-2019-125546
Published: 2019
Journal Articles

Dynamic Changes of Chromatin Structure and Transcriptome By Transient Expression of HTLV-1 Tax in ATL Cells

Daisuke Kurita, MD PhD, Jun-ichirou Yasunaga, MD PhD, Azusa Tanaka, PhD, Mahgoub Mohamed, MD PhD, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4094.
https://doi.org/10.1182/blood-2018-99-111125
Published: 2018
Journal Articles

TET2 Mutation Associated with Organ Infiltrations in ATLL

Takuro Kameda, MD, Kotaro Shide, MD PhD, Ayako Kamiunten, MD, Yuki Tahira, MD, Keiichi Akizuki, MD, Masaaki Sekine, MD, Tomonori Hidaka, MD, Yoko Kubuki, MD PhD, Michihiro Hidaka, MD PhD, Atae Utsunomiya, MD PhD, Takayuki Ohshima, Keisuke Kataoka, MD PhD, Seishi Ogawa, MD PhD, Kazuya Shimoda, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1345.
https://doi.org/10.1182/blood-2018-99-118065
Published: 2018
Journal Articles

Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model

Brief Report
Xingguo Zhu, Caixia Xi, Bobby Thomas, Betty S. Pace
Journal: Blood
Blood (2018) 131 (5): 558–562.
https://doi.org/10.1182/blood-2017-10-810531
Published: 2018
Includes: Supplemental data
Journal Articles

Treg in GVHD Prophylaxis: Unique Transcription Factor Regulation of Foxp3 Expression in Itreg Derived from Human Umbilical Cord Blood (UCB) Vs Adult (AB) Naive CD4 T Cells

Jeong-Su Do, PhD, Fei Zhong, MD, Twishari Dasgupta, PhD, Wouter van't Hof, PhD, Marcie Finney, MS, Mary Laughlin, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3191.
https://doi.org/10.1182/blood.V130.Suppl_1.3191.3191
Published: 2017
Journal Articles

Delineating the Functional Consequences of CEBPA Mutations in Acute Myeloid Leukaemia

Catherine Hockings, MBBChir, MA, FRCPath, MRCP, Jasmine Rowell, BS, MS, Oscar Pena, BS, MSc, Elspeth Payne, MDPhDFRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 1237.
https://doi.org/10.1182/blood.V130.Suppl_1.1237.1237
Published: 2017
Journal Articles

Loss of NRF2 Function Worsens the Pathophysiology of Sickle Cell Disease in a Transgenic Mouse Model

Xingguo Zhu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 960.
https://doi.org/10.1182/blood.V130.Suppl_1.960.960
Published: 2017
Journal Articles

The High NRF2 Expression Confers Chemotherapy Resistance through Upregulated DUSP1 in Myelodysplastic Syndromes

Peipei Lin, Yanling Ren, Xinping Zhou, Chen Mei, Chao Hu, Yingwan Luo, Yile Zhou, Xiaomei Yan, Gang Huang, PhD, Hongyan Tong, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2956.
https://doi.org/10.1182/blood.V130.Suppl_1.2956.2956
Published: 2017
Journal Articles

Differences Between CEBPA bZIP and TAD Mutations and Their Effect on Outcome-an Analysis in 4578 Patients with Acute Myeloid Leukemia

Julia-Annabell Georgi, Franziska Taube, MD, Michael Kramer, MSc, Sylvia Herold, PhD, Kerstin Schaefer-Eckart, MD, Norbert Schmitz, MD, PhD, Christian Eberlein, PhD, Sebastian Stasik, PhD, Walter E Aulitzky, MD, Alwin Kraemer, MD, Wolf Roesler, MD, Mathias Haenel, MD, Hermann Einsele, MD, Claudia D. Baldus, MD, Jan Moritz Middeke, MD, Uwe Platzbecker, MD, Christoph Roellig, MD, Hubert Serve, MD, Wolfgang E Berdel, MD, Gerhard Ehninger, MD, Martin Bornhaeuser, MD, Johannes Schetelig, MD PhD, Christian Thiede, MD
Journal: Blood
Blood (2016) 128 (22): 283.
https://doi.org/10.1182/blood.V128.22.283.283
Published: 2016
Journal Articles

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

Jun-ichirou Yasunaga, MDPhD, Rie Furuta, Michi Miura, Kenji Sugata, Akatsuki Saito, Akari Hirofumi, Takaharu Ueno, Norihiro Takenouchi, Jun-ichi Fujisawa, Masakazu Shimizu, Fumihiko Matsuda, MD PhD, Anat Melamed, Charles R. M. Bangham, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1343.
https://doi.org/10.1182/blood.V128.22.1343.1343
Published: 2016
Journal Articles

Functional Impairment of Co-Inhibitory Receptors Promotes T-Cell Proliferation in HTLV-1 Associated Adult T-Cell Leukemia Cells

Haruka Kinosada, Jun-ichirou Yasunaga, MDPhD, Kazuya Shimura, PhD, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2516.
https://doi.org/10.1182/blood.V128.22.2516.2516
Published: 2016
Journal Articles

Nrf2 Activation and Fetal Hemoglobin Induction in Sickle Cell Disease

Sriram Krishnamoorthy, Dipti Gupta, William E. Hobbs, MD PhD, Christine Loh, PhD, David R. Light, Robert Peters, PhD, Sarah Sturtevant, Betty Pace, MD, Yukio Nakamura, Brian Lucas, Benjamin F. Vieira
Journal: Blood
Blood (2016) 128 (22): 4840.
https://doi.org/10.1182/blood.V128.22.4840.4840
Published: 2016
Journal Articles

Suppression of Antioxidant Responses in Dyskeratosis Congenita Cells

Erik Westin, PhD, Larisa Pereboeva, MD PhD, Divya Devadasan, MS, Tim M. Townes, PhD, Frederick D Goldman, MD
Journal: Blood
Blood (2015) 126 (23): 2412.
https://doi.org/10.1182/blood.V126.23.2412.2412
Published: 2015
Journal Articles

Dimethyl Fumarate Induces Fetal Hemoglobin in Sickle Cell Disease

Sriram Krishnamoorthy, PhD, Dipti Gupta, MS, Sarah Sturtevant, Biaoru Li, PhD, Levi C Makala, DVM, MBA, PhD, William E. Hobbs, MDPhD, David R. Light, PhD, Betty Pace, MD
Journal: Blood
Blood (2015) 126 (23): 410.
https://doi.org/10.1182/blood.V126.23.410.410
Published: 2015
Journal Articles

The Combination of Belinostat with Zidovudine for Treatment of HTLV-I Related Adult T-Cell Leukemia-Lymphoma

Ngoc Toomey, Juan Carlos Ramos, MD
Journal: Blood
Blood (2015) 126 (23): 1562.
https://doi.org/10.1182/blood.V126.23.1562.1562
Published: 2015
Journal Articles

Protective effect of cytotoxic T lymphocytes targeting HTLV-1 bZIP factor

Kenji Sugata, Jun-ichirou Yasunaga, Yuichi Mitobe, Michi Miura, Paola Miyazato, Michinori Kohara, Masao Matsuoka
Journal: Blood
Blood (2015) 126 (9): 1095–1105.
https://doi.org/10.1182/blood-2015-04-641118
Published: 2015
Includes: Supplemental data