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Journal Articles

Nrf2 sensitizes ferroptosis through l-2-hydroxyglutarate–mediated chromatin modifications in sickle cell disease

Caixia Xi, Junfeng Pang, Wenbo Zhi, Chang-Sheng S. Chang, Umapathy Siddaramappa, Huidong Shi, Anatoli Horuzsko, Betty S. Pace, Xingguo Zhu
Journal: Blood
Blood (2023) 142 (4): 382–396.
https://doi.org/10.1182/blood.2022018159
Published: 2023
Includes: Supplemental data
Journal Articles

BACH1 Inhibitor Hpp-D Mediates γ-Globin Gene Activation in Sickle Erythroid Progenitors

Chithra D Palani, Xingguo Zhu, Manickam Alagar, Otis C Attucks, Betty S. Pace
Journal: Blood
Blood (2022) 140 (Supplement 1): 2521–2522.
https://doi.org/10.1182/blood-2022-169980
Published: 2022
Journal Articles

Salubrinal Mediated Fetal Hemoglobin Induction through the eIF2α-ATF4 Signaling Pathway

Nicole Hope Lopez, BS, Biaoru Li, MDPhD, Xingguo Zhu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32.
https://doi.org/10.1182/blood-2020-139969
Published: 2020
Journal Articles

NRF2 Mediates Epigenetic Changes in DNA and Chromatin Structure to Regulate γ-Globin Gene Expression in a Human βYAC Transgenic Mouse Model

Xingguo Zhu, PhD, Alexander H. Ward, PhD, Caixia Xi, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1053.
https://doi.org/10.1182/blood-2018-99-116438
Published: 2018
Journal Articles

Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model

Brief Report
Xingguo Zhu, Caixia Xi, Bobby Thomas, Betty S. Pace
Journal: Blood
Blood (2018) 131 (5): 558–562.
https://doi.org/10.1182/blood-2017-10-810531
Published: 2018
Includes: Supplemental data
Journal Articles

Novel Conjugates of Butyrate and δ-Aminolevulinate Increase γ-Globin Gene Expression and Fetal Hemoglobin Synthesis in Erythroid Progenitors

Aluya R. Oseghale, BSc, Marjorie M. Johnson, BS, Xingguo Zhu, PhD, Abraham Nudelman, PhD, Ada Rephaeli, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3511.
https://doi.org/10.1182/blood.V130.Suppl_1.3511.3511
Published: 2017
Journal Articles

Characterization of a HBB -Locus Fetal Chromatin Domain Region during Adult Erythropoiesis

Li Liu, PhD, Xingguo Zhu, PhD, Alexander Yu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2223.
https://doi.org/10.1182/blood.V130.Suppl_1.2223.2223
Published: 2017
Journal Articles

Loss of NRF2 Function Worsens the Pathophysiology of Sickle Cell Disease in a Transgenic Mouse Model

Xingguo Zhu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 960.
https://doi.org/10.1182/blood.V130.Suppl_1.960.960
Published: 2017
Journal Articles

A Facilitated Tracking and Transcription Mechanism of the HS2 Enhancer in the β-Globin Locus Control Region.

Dorothy Tuan, PhD, Xingguo Zhu, Ph.D., Jianhua Ling, Ph.D., Ling Zhang, Ph.D., Wenhu Pi, M.D., Min Wu, B.S.
Journal: Blood
Blood (2006) 108 (11): 1596.
https://doi.org/10.1182/blood.V108.11.1596.1596
Published: 2006