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Journal Articles

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

Xiaoqing Lu, Tharu M. Fernando, Chen Lossos, Nevin Yusufova, Fan Liu, Lorena Fontán, Matthew Durant, Huimin Geng, Jacob Melnick, Yuan Luo, Francisco Vega, Vincent Moy, Giorgio Inghirami, Stephen Nimer, Ari M. Melnick, Izidore S. Lossos

Blood (2018) 132 (19): 2026–2039.

https://doi.org/10.1182/blood-2018-02-831438

Published: 2018

Includes: Supplemental data

Journal Articles

Grb2 Directly Interacts with HGAL and Ameliorates Its Effects on B-Cell Receptor Signaling

Xiaoyu Jiang, PhD, Xiaoqing Lu, Brett J Schuchardt, David C Mikles, Amjad Farooq, Vincent Moy, PhD, Izidore S Lossos, MD

Blood (2015) 126 (23): 702.

https://doi.org/10.1182/blood.V126.23.702.702

Published: 2015

Journal Articles

HGAL localization to cell membrane regulates B-cell receptor signaling

Xiaoqing Lu, Renaud Sicard, Xiaoyu Jiang, Jessica N. Stockus, George McNamara, Midhat Abdulreda, Vincent T. Moy, Ralf Landgraf, Izidore S. Lossos

Blood (2015) 125 (4): 649–657.

https://doi.org/10.1182/blood-2014-04-571331

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

B Cell Receptors Of Chlamydophila Psittaci negative MALT Lymphomas Of The Ocular Adnexa Recognize Common Self-Antigens

Daxing Zhu, MD, Xiaoqing Lu, M.D, Marcus Dühren-von Minden, M.Sc., Shruti Bhatt, MS, Chen Lossos, Jennifer R. Chapman-Fredricks, MD, Hendrik Veelken, MD PhD, Hassan Jumaa, PhD, Izidore S Lossos, MD

Blood (2013) 122 (21): 4266.

https://doi.org/10.1182/blood.V122.21.4266.4266

Published: 2013

Journal Articles

Interaction of HGAL with Grb2 Enhances RhoA and B-Cell Receptor Signaling

Xiaoyu Jiang, PhD, Xiaoqing Lu, M.D, Izidore S Lossos, MD

Blood (2012) 120 (21): 681.

https://doi.org/10.1182/blood.V120.21.681.681

Published: 2012

Journal Articles

Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma

Elena Cubedo, Andrew J. Gentles, Chuanxin Huang, Yasodha Natkunam, Shruti Bhatt, Xiaoqing Lu, Xiaoyu Jiang, Isabel Romero-Camarero, Aharon Freud, Shuchun Zhao, Carlos E. Bacchi, Jose A. Martínez-Climent, Isidro Sánchez-García, Ari Melnick, Izidore S. Lossos

Blood (2012) 119 (23): 5478–5491.

https://doi.org/10.1182/blood-2012-01-403154

Published: 2012

Includes: Supplemental data

Journal Articles

Identification of LMO2 Transcriptome and Interactome in Diffuse Large B-Cell Lymphoma by Integrated Experimental and Computational Approach

Elena Cubedo, PhD, Andrew J. Gentles, Ph.D., Chuanxin Huang, PhD, Yasodha Natkunam, MD, PhD, Shruti Bhatt, Xiaoyu Jiang, PhD, Xiaoqing Lu, M.D, Isabel Romero-Camarero, Ph.D, Sylvia K. Plevritis, Jose A Martinez-Climent, MD, PhD, Isidro Sanchez-Garcia, MD, Ari Melnick, MD, Izidore S Lossos, MD

Blood (2011) 118 (21): 438.

https://doi.org/10.1182/blood.V118.21.438.438

Published: 2011

Journal Articles

HGAL-a Germinal Center Specific Protein, Enhances B-Cell Receptor Signaling by Activation of Syk, Leading to Follicular Lymphoproliferation

Xiaoyu Jiang, PhD, Isabel Romero-Camarero, Ph.D, Xiaoqing Lu, M.D, Carolina Vicente-Dueñas, Ines Gonzalez-Herrero, Teresa Flores, Juan Luis Garcia, George McNamara, Ph.D, Christian Kunder, Yasodha Natkunam, MD, PhD, Victor Segura, PhD, Lorenna Fontan-Gabas, Jose A Martinez-Climent, MD, PhD, Ash A Alizadeh, MD/PhD, Cesar Cobaleda, PhD, Isidro Sanchez-Garcia, MD, Izidore S Lossos, MD

Blood (2011) 118 (21): 584.

https://doi.org/10.1182/blood.V118.21.584.584

Published: 2011

Journal Articles

HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway

Xiaoyu Jiang, Xiaoqing Lu, George McNamara, Xiaofei Liu, Elena Cubedo, Kristopher A. Sarosiek, Isidro Sánchez-García, David M. Helfman, Izidore S. Lossos

Blood (2010) 116 (24): 5217–5227.

https://doi.org/10.1182/blood-2010-04-281568

Published: 2010

Includes: Multimedia, Supplemental data

Journal Articles

HGAL Directly Interacts with Both Myosin and Actin and Increases the Binding of Myosin to Actin

Xiaoqing Lu, MD, Kazmierczak Katarzyna, Ph.D, Xiaoyu Jiang, PhD, James Watt, Jeffrey R Moore, Ph.D, Danuta Szczesna-Cordary, Ph.D, Izidore S Lossos, MD

Blood (2010) 116 (21): 3097.

https://doi.org/10.1182/blood.V116.21.3097.3097

Published: 2010

Journal Articles

HGAL, a Lymphoma Prognostic Biomarker, Regulates Lymphocyte and Lymphoma Cell Motility by Modulation of RhoA Signaling Pathway.

Xiaoyu Jiang, PhD., Xiaoqing Lu, PhD, George Mcnamara, PhD, Xiaofei Liu, Kristopher A Sarosiek, PhD, David M. Helfman, PhD, Izidore S Lossos, MD

Blood (2009) 114 (22): 316.

https://doi.org/10.1182/blood.V114.22.316.316

Published: 2009

Journal Articles

PTP1B is a negative regulator of interleukin 4–induced STAT6 signaling

Xiaoqing Lu, Raquel Malumbres, Benjamin Shields, Xiaoyu Jiang, Kristopher A. Sarosiek, Yasodha Natkunam, Tony Tiganis, Izidore S. Lossos

Blood (2008) 112 (10): 4098–4108.

https://doi.org/10.1182/blood-2008-03-148726

Published: 2008

Journal Articles

HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration

Xiaoqing Lu, Jun Chen, Raquel Malumbres, Elena Cubedo Gil, David M. Helfman, Izidore S. Lossos

Blood (2007) 110 (13): 4268–4277.

https://doi.org/10.1182/blood-2007-04-087775

Published: 2007

Journal Articles

PTP1B, Distinctively Expressed in GCB-Like and ABC-Like DLBCL, Is a New Regulator of IL-4-STAT6 Intracellular Signaling.

XiaoQing Lu, MD, Raquel Malumbres, PhD, Tony Tiganis, PhD, Izidore S. Lossos, MD

Blood (2007) 110 (11): 1558.

https://doi.org/10.1182/blood.V110.11.1558.1558

Published: 2007

Journal Articles

PTPN2, Distinctively Expressed in GCB-Like and ABC-Like DLBCL, Is the Nuclear Phosphatase of STAT6.

Izidore S. Lossos, MD, XiaoQing Lu, MD, Tony Tiganis, PhD

Blood (2005) 106 (11): 418.

https://doi.org/10.1182/blood.V106.11.418.418

Published: 2005

Journal Articles

Expression of the human germinal center–associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation

Yasodha Natkunam, Izidore S. Lossos, Behnaz Taidi, Shuchun Zhao, XiaoQing Lu, Feying Ding, Anne Sofie Hammer, Teresa Marafioti, Gerald E. Byrne, Jr, Shoshana Levy, Roger A Warnke, Ronald Levy

Blood (2005) 105 (10): 3979–3986.

https://doi.org/10.1182/blood-2004-08-3112

Published: 2005

Journal Articles

Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas

Xiaoqing Lu, Hovav Nechushtan, Feiying Ding, Manuel F. Rosado, Rakesh Singal, Ash A. Alizadeh, Izidore S. Lossos

Blood (2005) 105 (7): 2924–2932.

https://doi.org/10.1182/blood-2004-10-3820

Published: 2005

Includes: Supplemental data

Journal Articles

Distinct IL-4 Intracellular Signaling in Germinal Center B-Cell like and Activated B-Cell like Diffuse Large B-Cell Lymphoma: Novel Opportunities for Therapeutic Interventions.

Izidore S. Lossos, MD, XiaoQing Lu, MD, Feiying Ding, Manuel Rosado, MD, Ash A. Alizadeh, MD. PhD, Hovav Nechushtan, MD, PhD

Blood (2004) 104 (11): 244.

https://doi.org/10.1182/blood.V104.11.244.244

Published: 2004

Journal Articles

Expression of the Human Germinal Center-Associated Lymphoma (HGAL) Protein, a New Marker of Germinal Center B Cell Derivation.

Yasodha Natkunam, MD, PhD, Izidore S. Lossos, MD, Behnaz Taidi, Shuchun Zhao, MS, XiaoQing Lu, Feying Ding, Anne S. Hammer, PhD, Teresa Marafioti, PhD, Gerald E. Byrne, MD, Shoshana Levy, PhD, Roger A. Warnke, MD, Ronald Levy, MD

Blood (2004) 104 (11): 2265.

https://doi.org/10.1182/blood.V104.11.2265.2265

Published: 2004

NARROW

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

Grb2 Directly Interacts with HGAL and Ameliorates Its Effects on B-Cell Receptor Signaling

HGAL localization to cell membrane regulates B-cell receptor signaling

B Cell Receptors Of Chlamydophila Psittaci negative MALT Lymphomas Of The Ocular Adnexa Recognize Common Self-Antigens

Interaction of HGAL with Grb2 Enhances RhoA and B-Cell Receptor Signaling

Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma

Identification of LMO2 Transcriptome and Interactome in Diffuse Large B-Cell Lymphoma by Integrated Experimental and Computational Approach

HGAL-a Germinal Center Specific Protein, Enhances B-Cell Receptor Signaling by Activation of Syk, Leading to Follicular Lymphoproliferation

HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway

HGAL Directly Interacts with Both Myosin and Actin and Increases the Binding of Myosin to Actin

HGAL, a Lymphoma Prognostic Biomarker, Regulates Lymphocyte and Lymphoma Cell Motility by Modulation of RhoA Signaling Pathway.

PTP1B is a negative regulator of interleukin 4–induced STAT6 signaling

HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration

PTP1B, Distinctively Expressed in GCB-Like and ABC-Like DLBCL, Is a New Regulator of IL-4-STAT6 Intracellular Signaling.

PTPN2, Distinctively Expressed in GCB-Like and ABC-Like DLBCL, Is the Nuclear Phosphatase of STAT6.

Expression of the human germinal center–associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation

Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas

Distinct IL-4 Intracellular Signaling in Germinal Center B-Cell like and Activated B-Cell like Diffuse Large B-Cell Lymphoma: Novel Opportunities for Therapeutic Interventions.

Expression of the Human Germinal Center-Associated Lymphoma (HGAL) Protein, a New Marker of Germinal Center B Cell Derivation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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