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Xiang-Zuo Pan
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Journal Articles

Complement biosensors identify a classical pathway stimulus in complement-mediated thrombotic microangiopathy

Michael A. Cole, Nikhil Ranjan, Gloria F. Gerber, Xiang-Zuo Pan, Daniel Flores-Guerrero, George McNamara, Shruti Chaturvedi, C. John Sperati, Keith R. McCrae, Robert A. Brodsky
Journal: Blood
Blood (2024) 144 (24): 2528–2545.
https://doi.org/10.1182/blood.2024025850
Published: 2024
Includes: Supplemental data
Journal Articles

Complement Biosensors Can be Used to Identify Classical Pathway and Alternative Pathway Dysregulation in Complement-Mediated Thrombotic Microangiopathy

Michael Cole, Nikhil Ranjan, Gloria F. Gerber, Xiang-Zuo Pan, Daniel Flores-Guerrero, Shruti Chaturvedi, C. John Sperati, Keith R. McCrae, Robert A. Brodsky
Journal: Blood
Blood (2024) 144 (Supplement 1): 1225.
https://doi.org/10.1182/blood-2024-210885
Published: 2024
Journal Articles

The Bioluminescent Modified Ham Test Identifies the Classical Pathway As the Major Driver of Complement Activation in Atypical Hemolytic Uremic Syndrome and Primary Antiphospholipid Syndrome

Michael Cole, Gloria F. Gerber, Xiang-Zuo Pan, Nikhil Ranjan, John Sperati, Shruti Chaturvedi, Keith R. McCrae, Robert A. Brodsky
Journal: Blood
Blood (2023) 142 (Supplement 1): 3947.
https://doi.org/10.1182/blood-2023-190615
Published: 2023
Journal Articles

Sars-Cov-2 Spike Protein Triggers Inflammasome-Mediated Tissue Factor Activity

Nikhil Ranjan, Molly Kuzma, Xiang-Zuo Pan, Michael Cole, Robert A. Brodsky, Gloria F. Gerber
Journal: Blood
Blood (2023) 142 (Supplement 1): 5405.
https://doi.org/10.1182/blood-2023-187738
Published: 2023
Journal Articles

A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism

John F. Andersen, Haotian Lei, Ethan C. Strayer, Tapan Kanai, Van Pham, Xiang-Zuo Pan, Patricia Hessab Alvarenga, Gloria F. Gerber, Oluwatoyin A. Asojo, Ivo M. B. Francischetti, Robert A. Brodsky, Jesus G. Valenzuela, José M. C. Ribeiro
Journal: Blood
Blood (2023) 141 (25): 3109–3121.
https://doi.org/10.1182/blood.2022019359
Published: 2023
Includes: Supplemental data
Journal Articles

Silent Cerebral Infarction during Immune TTP Remission - Prevalence, Predictors and Impact on Cognition

Jia Yu, Jenna Brown, Eli Salzberg, Aria Wei, Gloria Gerber, Xiang-Zuo Pan, Alison R. Moliterno, MIchael B. Streiff, Peggy Kraus, Claire Logue, Jennifer Yui, Rakhi P.P. Naik, Hira Latif, Sophie M. Lanzkron, Evan M. Braunstein, Robert Brodsky, Michael R. DeBaun, Doris Lin, Shruti Chaturvedi
Journal: Blood
Blood (2022) 140 (Supplement 1): 338–340.
https://doi.org/10.1182/blood-2022-167054
Published: 2022
Journal Articles

Pathogenicity of Sars-Cov-2 Spike Protein Variants Correlates with Coagulation and Complement Assays

Gloria Gerber, Xiang-Zuo Pan, Nikhil Ranjan, Anna Warmack, Robert Brodsky
Journal: Blood
Blood (2022) 140 (Supplement 1): 2705–2706.
https://doi.org/10.1182/blood-2022-169738
Published: 2022
Journal Articles

Abundance of B Cell Receptors Harboring Elongated Polytyrosine and Polyserine Rich Motifs within Their Heavy Chain CDR3 Distinguishes Catastrophic and Antiphospholipid Syndrome

Shadi Swaidani, Shruti Chaturvedi, Xiang-Zuo Pan, Robert Brodsky, Renren Wen, Alok A Khorana, Keith R. McCrae
Journal: Blood
Blood (2021) 138 (Supplement 1): 2117.
https://doi.org/10.1182/blood-2021-148158
Published: 2021
Journal Articles

Silent Cerebral Infarction on Brain MRI Is Associated with Cognitive Impairment in Ittp Survivors in Hematological Remission

Jia Yu, Aria Wei, Xiang-Zuo Pan, Gloria Frances Gerber, Sarah Hussain, Alison R. Moliterno, Michael B. Streiff, Peggy Kraus, Claire Logue, Jennifer Yui, Rakhi P. Naik, Hira Latif, Ruhail Kohli, Sophie M. Lanzkron, Evan M. Braunstein, Robert Brodsky, Doris Lin, Shruti Chaturvedi
Journal: Blood
Blood (2021) 138 (Supplement 1): 774.
https://doi.org/10.1182/blood-2021-151304
Published: 2021