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C. John Sperati
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Journal Articles

Complement biosensors identify a classical pathway stimulus in complement-mediated thrombotic microangiopathy

Michael A. Cole, Nikhil Ranjan, Gloria F. Gerber, Xiang-Zuo Pan, Daniel Flores-Guerrero, George McNamara, Shruti Chaturvedi, C. John Sperati, Keith R. McCrae, Robert A. Brodsky
Journal: Blood
Blood (2024) 144 (24): 2528–2545.
https://doi.org/10.1182/blood.2024025850
Published: 2024
Includes: Supplemental data
Journal Articles

Complement Biosensors Can be Used to Identify Classical Pathway and Alternative Pathway Dysregulation in Complement-Mediated Thrombotic Microangiopathy

Michael Cole, Nikhil Ranjan, Gloria F. Gerber, Xiang-Zuo Pan, Daniel Flores-Guerrero, Shruti Chaturvedi, C. John Sperati, Keith R. McCrae, Robert A. Brodsky
Journal: Blood
Blood (2024) 144 (Supplement 1): 1225.
https://doi.org/10.1182/blood-2024-210885
Published: 2024
Journal Articles

Reduced ADAMTS13 activity during TTP remission is associated with stroke in TTP survivors

Clinical Trials & Observations
Harshvardhan Upreti, Jamil Kasmani, Kathryn Dane, Evan M. Braunstein, Michael B. Streiff, Satish Shanbhag, Alison R. Moliterno, C. John Sperati, Rebecca F. Gottesman, Robert A. Brodsky, Thomas S. Kickler, Shruti Chaturvedi
Journal: Blood
Blood (2019) 134 (13): 1037–1045.
https://doi.org/10.1182/blood.2019001056
Published: 2019
Includes: Supplemental data
Journal Articles

Eculizumab cessation in atypical hemolytic uremic syndrome

Clinical Trials & Observations
Samuel A. Merrill, Zachary D. Brittingham, Xuan Yuan, Alison R. Moliterno, C. John Sperati, Robert A. Brodsky
Journal: Blood
Blood (2017) 130 (3): 368–372.
https://doi.org/10.1182/blood-2017-02-770214
Published: 2017
Includes: Supplemental data
Journal Articles

β-2-Glycoprotein Antibodies Activate the Alternative Pathway of Complement in Antiphospholipid Antibody Syndrome

Andrea C. Baines, MD PhD, Xuan Yuan, MD MSc, Eleni Gavriilaki, MD PhD, Alexander J. Ambinder, MD MPH, Alka Jain, PhD, Neal S. Fedarko, PhD, C. John Sperati, MD MHS, Alison R. Moliterno, MD, Rakhi P. Naik, MD MHS, Michael Streiff, MD, Wei Fu, MS, Michelle Petri, MD MPH, Robert A. Brodsky, MD
Journal: Blood
Blood (2016) 128 (22): 3818.
https://doi.org/10.1182/blood.V128.22.3818.3818
Published: 2016
Journal Articles

Modified Ham test for atypical hemolytic uremic syndrome

Eleni Gavriilaki, Xuan Yuan, Zhaohui Ye, Alexander J. Ambinder, Satish P. Shanbhag, Michael B. Streiff, Thomas S. Kickler, Alison R. Moliterno, C. John Sperati, Robert A. Brodsky
Journal: Blood
Blood (2015) 125 (23): 3637–3646.
https://doi.org/10.1182/blood-2015-02-629683
Published: 2015
Includes: Supplemental data