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Journal Articles

Complement-induced procoagulant platelets in patients with antiphospholipid antibodies

Free
Paresh Kulkarni, Maierdan Palihati, Anne Hubben, Michael Cole, Bhagwati Joshi, Dana Angelini, Sandra Mazzoni, Shruti Chaturvedi, Robert Brodsky, Keith McCrae
Journal: Blood
Blood (2025) 146 (Supplement 1): 416.
https://doi.org/10.1182/blood-2025-416
Published: 2025
Journal Articles

Enhanced procoagulant activity of phosphatidylserine-positive platelets in antiphospholipid syndrome

Free
Charles Sukin, Paresh Kulkarni, Anne Hubben, Bhagwati Joshi, Michael Cole, Dana Angelini, Sandra Mazzoni, Robert Brodsky, Keith McCrae
Journal: Blood
Blood (2025) 146 (Supplement 1): 1249.
https://doi.org/10.1182/blood-2025-1249
Published: 2025
Journal Articles

NLRP3 inflammasome inhibition fails to prevent red blood cell lysis in PNH

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Nikhil Ranjan, Michael Cole, Gloria Gerber, Daniel Flores-Guerrero, Shruti Chaturvedi, Robert Brodsky
Journal: Blood
Blood (2025) 146 (Supplement 1): 2895.
https://doi.org/10.1182/blood-2025-2895
Published: 2025
Journal Articles

Rapidly progressive acute chest syndrome is associated with complement-mediated cell injury in adults with sickle cell disease

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Jose Mejias Figueroa, Shruti Chaturvedi, Michael DeBaun, Gloria Gerber, Robert Brodsky, Michael Cole, Daniel Flores-Guerrero, Xuan Yuan
Journal: Blood
Blood (2025) 146 (Supplement 1): 6485.
https://doi.org/10.1182/blood-2025-6485
Published: 2025
Journal Articles

Optimizing Complement Inhibitor Monitoring in PNH and Beyond

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Michael Cole, Nikhil Ranjan, Daniel G. Flores, Molly Kuzma, Alexis Reed, Robert A. Brodsky, Gloria F. Gerber
Journal: Blood
Blood (2024) 144 (Supplement 1): 4071.
https://doi.org/10.1182/blood-2024-200838
Published: 2024
Journal Articles

Genetic or Epigenetic CR1 Deficiency Defines Catastrophic Antiphospholipid Syndrome (CAPS) and Response to Complement Inhibition

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Nikhil Ranjan, Michael Cole, Gloria F. Gerber, Shruti Chaturvedi, Mark A. Crowther, Evan M. Braunstein, Daniel Flores-Guerrero, Alexis Reed, Michelle Petri, Keith R. McCrae, Robert A. Brodsky
Journal: Blood
Blood (2024) 144 (Supplement 1): 138.
https://doi.org/10.1182/blood-2024-207793
Published: 2024
Journal Articles

Complement Biosensors Can be Used to Identify Classical Pathway and Alternative Pathway Dysregulation in Complement-Mediated Thrombotic Microangiopathy

Free
Michael Cole, Nikhil Ranjan, Gloria F. Gerber, Xiang-Zuo Pan, Daniel Flores-Guerrero, Shruti Chaturvedi, C. John Sperati, Keith R. McCrae, Robert A. Brodsky
Journal: Blood
Blood (2024) 144 (Supplement 1): 1225.
https://doi.org/10.1182/blood-2024-210885
Published: 2024
Journal Articles

The Bioluminescent Modified Ham Test Identifies the Classical Pathway As the Major Driver of Complement Activation in Atypical Hemolytic Uremic Syndrome and Primary Antiphospholipid Syndrome

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Michael Cole, Gloria F. Gerber, Xiang-Zuo Pan, Nikhil Ranjan, John Sperati, Shruti Chaturvedi, Keith R. McCrae, Robert A. Brodsky
Journal: Blood
Blood (2023) 142 (Supplement 1): 3947.
https://doi.org/10.1182/blood-2023-190615
Published: 2023
Journal Articles

Circulating Platelets in Thrombotic Antiphospholipid Syndrome Display High Procoagulant Activity and Surface Complement Deposition: Correlation with Thrombotic Risk

Free
Paresh P Kulkarni, Young Jun Shim, Anne K Hubben, Michael Cole, Shruti Chaturvedi, Robert A. Brodsky, Keith R McCrae
Journal: Blood
Blood (2023) 142 (Supplement 1): 5407.
https://doi.org/10.1182/blood-2023-184601
Published: 2023
Journal Articles

Sars-Cov-2 Spike Protein Triggers Inflammasome-Mediated Tissue Factor Activity

Free
Nikhil Ranjan, Molly Kuzma, Xiang-Zuo Pan, Michael Cole, Robert A. Brodsky, Gloria F. Gerber
Journal: Blood
Blood (2023) 142 (Supplement 1): 5405.
https://doi.org/10.1182/blood-2023-187738
Published: 2023