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Ivo M. B. Francischetti
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Journal Articles

A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism

John F. Andersen, Haotian Lei, Ethan C. Strayer, Tapan Kanai, Van Pham, Xiang-Zuo Pan, Patricia Hessab Alvarenga, Gloria F. Gerber, Oluwatoyin A. Asojo, Ivo M. B. Francischetti, Robert A. Brodsky, Jesus G. Valenzuela, José M. C. Ribeiro
Journal: Blood
Blood (2023) 141 (25): 3109–3121.
https://doi.org/10.1182/blood.2022019359
Published: 2023
Includes: Supplemental data
Journal Articles

NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition

Viviane S. De Paula, Nikolaos G. Sgourakis, Ivo M. B. Francischetti, Fabio C. L. Almeida, Robson Q. Monteiro, Ana Paula Valente
Journal: Blood
Blood (2019) 134 (8): 699–708.
https://doi.org/10.1182/blood.2018889493
Published: 2019
Includes: Supplemental data
Journal Articles

Hairy cell leukemia coexistent with chronic lymphocytic leukemia

Ivo M. B. Francischetti, Katherine R. Calvo
Journal: Blood
Blood (2019) 133 (11): 1264.
https://doi.org/10.1182/blood-2018-12-885145
Published: 2019
Journal Articles

Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat ( Desmodus rotundus ) inhibits inflammation and thrombosis in vivo

Dongying Ma, Daniella M. Mizurini, Teresa C. F. Assumpção, Yuan Li, Yanwei Qi, Michail Kotsyfakis, José M. C. Ribeiro, Robson Q. Monteiro, Ivo M. B. Francischetti
Journal: Blood
Blood (2013) 122 (25): 4094–4106.
https://doi.org/10.1182/blood-2013-08-517474
Published: 2013
Includes: Supplemental data
Journal Articles

A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

Jindrich Chmelar, Carlo J. Oliveira, Pavlina Rezacova, Ivo M. B. Francischetti, Zuzana Kovarova, Gunnar Pejler, Peter Kopacek, José M. C. Ribeiro, Michael Mares, Jan Kopecky, Michail Kotsyfakis
Journal: Blood
Blood (2011) 117 (2): 736–744.
https://doi.org/10.1182/blood-2010-06-293241
Published: 2011
Includes: Supplemental data
Journal Articles

Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex

Ivo M. B. Francischetti, Jesus G. Valenzuela, John F. Andersen, Thomas N. Mather, José M. C. Ribeiro
Journal: Blood
Blood (2002) 99 (10): 3602–3612.
https://doi.org/10.1182/blood-2001-12-0237
Published: 2002