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Journal Articles

Bringing Hematological Malignancy Clinical Trials to Patients: Mayo Clinic LLS Impact Experience

Jamie Johnston, Katie J. Doane, Wesley Waszak, Carolyn Flock, Arushi Khurana, Nina Logan, Nanci Hawley, Eyad Al-Hattab, Akeem R. Lewis, Jonathan Ticku, Amir Yosef, Stephen M. Ansell, Shaji Kumar, Sameer A. Parikh, Mithun V Shah, Thomas E. Witzig, Grzegorz S. Nowakowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 784.
https://doi.org/10.1182/blood-2024-205791
Published: 2024
Journal Articles

TP53 mutations and Complex Karyotype in Newly-Diagnosed Blast/Accelerated Phase MPN Are Associated with Ephemeral Response to Treatment with Venetoclax + HMA and Poor Survival

Naseema Gangat, Kristen B. McCullough, Azeem Elbeih, Nour Ghosoun, Maymona Abdelmagid, Aref Al-Kali, Hassan B Alkhateeb, Kebede Begna, Michelle A Elliott, Mark R. Litzow, Mehrdad Hefazi, William J. Hogan, Abhishek A. Mangaonkar, Antoine N. Saliba, Mithun V Shah, Talha Badar, James M. Foran, Jeanne Palmer, Cecilia Y. Arana Yi, Mrinal M. Patnaik, Animesh D. Pardanani, Ayalew Tefferi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6657.
https://doi.org/10.1182/blood-2024-193917
Published: 2024
Journal Articles

TP53 -Mutated Therapy-Related Myeloid Neoplasms Are Associated with a Long Latency and Are More Prevalent in Patients with Primary Hematological Cancers Compared to Solid Tumors

Kevin Hung, Aref Al-Kali, Carla Toop, Mrinal M. Patnaik, Zoe Price, Taxiarchis Kourelis, Daniel Thomas, Morie A. Gertz, Hossein Anani, Wilson I. Gonsalves, Chung Hoow Kok, Ayalew Tefferi, Devendra Hiwase, Mithun V Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 4594.
https://doi.org/10.1182/blood-2024-211931
Published: 2024
Journal Articles

Clinical Characteristics and Prognostic Significance of Co-Mutated SETBP1 / GATA2 Myeloid Neoplasms

Yazan Jabban, Rong He, Kurt Bessonen, Patricia Greipp, Dragan Jevremovic, James M. Foran, Cecilia Y. Arana Yi, Antoine N. Saliba, Mehrdad Hefazi, Aasiya Matin, William J. Hogan, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Mithun V Shah, Hassan B Alkhateeb, Aref Al-Kali
Journal: Blood
Blood (2024) 144 (Supplement 1): 6700.
https://doi.org/10.1182/blood-2024-201128
Published: 2024
Journal Articles

TP53 Mutations in Myeloproliferative Neoplasms: Context-Dependent Evaluation of Prognostic Relevance

Ayalew Tefferi, Maymona Abdelmagid, Giuseppe Gaetano Loscocco, Kebede Begna, Aref Al-Kali, James M. Foran, Jeanne Palmer, Talha Badar, Mrinal M. Patnaik, Kaaren K. Reichard, Rong He, Cinthya Zepeda Mendoza, Mithun V Shah, Attilio Orazi, Daniel A. Arber, Animesh D. Pardanani, Alessandro M. Vannucchi, Devendra Hiwase, Naseema Gangat, Paola Guglielmelli
Journal: Blood
Blood (2024) 144 (Supplement 1): 244.
https://doi.org/10.1182/blood-2024-210251
Published: 2024
Journal Articles

Subclassification of Erdheim-Chester Disease: Distinct Clinical and Molecular Findings between Classical and Non-Classical Forms

Dongni Yi, Ronald S Go, Gordon J Ruan, N. Nora Bennani, Mithun V Shah, Karen L Rech, Aishwarya Ravindran, Jay H Ryu, Robert Vassallo, Matthew J Koster, Caroline J Davidge-Pitts, Lucinda M Gruber, William Oliver Tobin, Julio C Sartori Valinotti, Talal Hilal, Liuyan Jiang, Muhamad Alhaj Moustafa, Asra Z. Ahmed, Gaurav Goyal, Jithma P Abeykoon
Journal: Blood
Blood (2024) 144 (Supplement 1): 3181.
https://doi.org/10.1182/blood-2024-193841
Published: 2024
Journal Articles

Cytokine Profile Comparisons Among Cytokine Release Syndrome (CRS), Macrophage Activation-like Syndrome (MAS-L) and Immune Effector Cell-Associated Hemophagocytic Syndrome (IEC-HS) in CAR-T Therapy

Supriya Gupta, Andre Corraes, Hassan B Alkhateeb, Alice Gallo de Moraes, Paschalis Vergidis, Radhika Bansal, Saad S. Kenderian, Urshila Durani, Jonas Paludo, Arushi Khurana, Joselle Cook, N. Nora Bennani, Jose C. Villasboas Bisneto, Mithun V Shah, Taxiarchis Kourelis, Nadine Abdallah, Yucai Wang, Morie A. Gertz, Rahma M Warsame, Suzanne R Hayman, Prashant Kapoor, Stephen M. Ansell, Shaji Kumar, David Dingli, Tyler B. Sandahl, Adrienne N. Nedved, Jason Barreto, Robert C Wolf, Patrick B. Johnston, Yi Lin, Nelson Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 7165.
https://doi.org/10.1182/blood-2024-211111
Published: 2024
Journal Articles

Gilteritinib Results in Higher Remission and Transplant Rates Than Midostaurin but Does Not Increase the Post-Induction Mutational MRD Negative Rate: Results of the Phase 2 Randomized Precog 0905 Study in Newly Diagnosed FLT3 Mutated AML

Selina Luger, Li Chen, Keith W. Pratz, Sanam Loghavi, Alexander E. Perl, Jessica K. Altman, Robert L. Redner, Amir T. Fathi, Ayman Qasrawi, Adam S. Asch, Deepa Jeyakumar, James M. Foran, Mithun V Shah, Jonathan E Kolitz, Ellin Berman, Lindsay Wilde, Sameem Abedin, Vamsi K. Kota, Krishna Gundabolu, Kristen M. O'Dwyer, Emily K Curran, Ashwin Kishtagari, Kelly Ross, Zhuoxin Sun, Mark R. Litzow
Journal: Blood
Blood (2024) 144 (Supplement 1): 221.
https://doi.org/10.1182/blood-2024-201595
Published: 2024
Journal Articles

Venetoclax in Combination with Hypomethylating Agent (HMA) Compared to HMA Alone Improves Response but Not Survival in TP53- mutated High-Risk Myelodysplastic Syndrome: Real-World Mayo Clinic Series

Talha Badar, Kashish J. Shah, Mobachir El Kettani, James M. Foran, Mohamed A. Kharfan-Dabaja, Hemant S. Murthy, Naseema Gangat, Aref Al-Kali, Mithun V Shah, Hassan B Alkhateeb, Antoine N. Saliba, William J. Hogan, Cecilia Y. Arana Yi, Lisa Sproat, Jeanne Palmer, Mark R. Litzow, Mrinal M. Patnaik
Journal: Blood
Blood (2024) 144 (Supplement 1): 1823.
https://doi.org/10.1182/blood-2024-203825
Published: 2024
Journal Articles

Efficacy of Small Molecule Kinase Inhibitors in Histiocytic Neoplasms with Non-BRAFV600E Mutations: Concordance of Pre-Clinical Predictions to Clinical Responses

Alanis Enid Rodriguez-Rosario, Aldo Adrian Acosta Medina, N. Nora Bennani, Gaurav Goyal, Aishwarya Ravindran, Karen L Rech, Gordon J Ruan, Mithun V Shah, Dongni Yi, Saurabh Zanwar, Jithma P Abeykoon, Ronald S Go
Journal: Blood
Blood (2024) 144 (Supplement 1): 4564.
https://doi.org/10.1182/blood-2024-205474
Published: 2024
Journal Articles

A Clinical Overview of Clonal Cytopenia of Undetermined Significance in the Presence of ZRSR2 Mutations

Mahmoud Yacout, Bahga Katamesh, Yazan Jabban, Rong He, Patricia Greipp, Dragan Jevremovic, James M. Foran, Cecilia Y. Arana Yi, Antoine N. Saliba, Abhishek A. Mangaonkar, Mithun V Shah, Mrinal M. Patnaik, Hassan B Alkhateeb, Aref Al-Kali
Journal: Blood
Blood (2024) 144 (Supplement 1): 2667.
https://doi.org/10.1182/blood-2024-208957
Published: 2024
Journal Articles

Response-Stratified Genetic Risk Model for Newly-Diagnosed Acute Myeloid Leukemia Treated with Venetoclax + Hypomethylating Agent

Naseema Gangat, Azeem Elbeih, Nour Ghosoun, Kristen B. McCullough, Isla Johnson, Maymona Abdelmagid, Aref Al-Kali, Hassan B Alkhateeb, Kebede Begna, Michelle A Elliott, Abhishek A. Mangaonkar, Aasiya Matin, Antoine N. Saliba, Mehrdad Hefazi, Mark R. Litzow, William J. Hogan, Mithun V Shah, Mrinal M. Patnaik, Animesh D. Pardanani, Talha Badar, Hemant S. Murthy, James M. Foran, Jeanne Palmer, Lisa Sproat, Nandita Khera, Cecilia Y. Arana Yi, Ayalew Tefferi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4247.
https://doi.org/10.1182/blood-2024-204114
Published: 2024
Journal Articles

Clinical Outcome and Molecular Profile in Patients with DDX41 Mutation Hotspots: A Retrospective Study of 82 Patients

Nadia Toumeh, Yazan Jabban, Ahmad Nanaa, Rong He, David Viswanatha, Dragan Jevremovic, James M. Foran, Cecilia Y. Arana Yi, Antoine N. Saliba, Mehrdad Hefazi, William J. Hogan, Mithun V Shah, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Hassan B Alkhateeb, Aref Al-Kali
Journal: Blood
Blood (2024) 144 (Supplement 1): 2869.
https://doi.org/10.1182/blood-2024-209413
Published: 2024
Journal Articles

Predictors of Relapse and Post-Relapse Outcomes in Patients with Newly-Diagnosed Acute Myeloid Leukemia Treated with Venetoclax + Hypomethylating Agent

Azeem Elbeih, Nour Ghosoun, Kristen B. McCullough, Isla Johnson, Maymona Abdelmagid, Aref Al-Kali, Hassan B Alkhateeb, Kebede Begna, Michelle A Elliott, Abhishek A. Mangaonkar, Aasiya Matin, Antoine N. Saliba, Mehrdad Hefazi, Mark R. Litzow, William J. Hogan, Mithun V Shah, Mrinal M. Patnaik, Animesh D. Pardanani, Talha Badar, Hemant S. Murthy, James M. Foran, Jeanne Palmer, Lisa Sproat, Nandita Khera, Cecilia Y. Arana Yi, Ayalew Tefferi, Naseema Gangat
Journal: Blood
Blood (2024) 144 (Supplement 1): 2852.
https://doi.org/10.1182/blood-2024-209015
Published: 2024
Journal Articles

Correlation between Pre-Apheresis Biomarkers and Development of Severe Cytopenias and Therapy-Related Myeloid Neoplasms in Non-Hodgkin Lymphoma Patients Undergoing Chimeric Antigen Receptor T-Cell Therapy

Andre De Menezes Silva Corraes, Anmol Baranwal, Radhika Bansal, Mark Gurney, Allison C. Rosenthal, Mohamed A. Kharfan-Dabaja, Arushi Khurana, Patrick B. Johnston, Stephen M. Ansell, Prashant Kapoor, Morie A. Gertz, Shaji Kumar, David Dingli, Urshila Durani, Jose C. Villasboas Bisneto, Saad S. Kenderian, Hassan B Alkhateeb, Yi Lin, Yucai Wang, Mithun V Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 2372.
https://doi.org/10.1182/blood-2024-210474
Published: 2024
Journal Articles

Characteristics and Outcomes of Patients with Second Hematological Malignancies after Autologous Hematopoietic Cell Transplantation for Multiple Myeloma

Binoy Yohannan, Angela Dispenzieri, Francis Buadi, David Dingli, Nelson Leung, Prashant Kapoor, Wilson I. Gonsalves, Taxiarchis Kourelis, Joselle Cook, Moritz Binder, Suzanne R Hayman, Yi Lin, Ronald S Go, Rahma M Warsame, Vincent Rajkumar, Shaji Kumar, Eli Muchtar, Hassan B Alkhateeb, William J. Hogan, Mark R. Litzow, Mrinal M. Patnaik, Aref Al-Kali, Abhishek Mangaonkar, Robert C Wolf, Mithun V Shah, Morie A. Gertz
Journal: Blood
Blood (2024) 144 (Supplement 1): 5149.
https://doi.org/10.1182/blood-2024-210932
Published: 2024
Journal Articles

Evidence-Based Risk Stratification of TP53 -Mutated Myeloid Neoplasms

Mithun V Shah, Kevin Hung, Anmol Baranwal, Zoe Price, Aref Al-Kali, Carla Toop, Patricia Greipp, Anna Brown, Dariusz Ladon, Dong Chen, Kebede Begna, Monika Kutyna, Danielle Rud, Mark R. Litzow, William J. Hogan, Peter Bardy, Talha Badar, Sharad Kumar, David T Yeung, Mrinal M. Patnaik, James M. Foran, Rong He, Naseema Gangat, Hamish S Scott, Cecilia Y. Arana Yi, Hassan B Alkhateeb, Abhishek A. Mangaonkar, Daniel Thomas, Christopher N. Hahn, Attilio Orazi, Daniel A. Arber, Chung Hoow Kok, Ayalew Tefferi, Devendra Hiwase
Journal: Blood
Blood (2024) 144 (Supplement 1): 3213.
https://doi.org/10.1182/blood-2024-198269
Published: 2024
Journal Articles

Risk of Relapse Post Reduced Intensity Conditioning Allogeneic Stem Cell Transplant in Patients with High-Risk Myeloid Neoplasms Based on Ptcy Vs TAC/MTX Gvhd Prophylaxis

Khalil Hassan, Anmol Baranwal, Abhishek A. Mangaonkar, Mehrdad Hefazi, Aasyia Matin, Mark R. Litzow, William J. Hogan, Mithun V Shah, Hassan B Alkhateeb
Journal: Blood
Blood (2024) 144 (Supplement 1): 4918.
https://doi.org/10.1182/blood-2024-199783
Published: 2024
Journal Articles

Efficacy of Targeted Agents and Immune Checkpoint Inhibitors in Patients with Malignant Histiocytosis

Alanis Enid Rodriguez-Rosario, Aldo Adrian Acosta Medina, N. Nora Bennani, Gaurav Goyal, Aishwarya Ravindran, Karen L Rech, Gordon J Ruan, Mithun V Shah, Dongni Yi, Saurabh Zanwar, Jithma P Abeykoon, Ronald S Go
Journal: Blood
Blood (2024) 144 (Supplement 1): 4563.
https://doi.org/10.1182/blood-2024-204398
Published: 2024
Journal Articles

IDH -mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation

Lih En Hong, Mihir D. Wechalekar, Monika Kutyna, Annabelle Small, Kelly Lim, Chloe Thompson-Peach, Joule J. Li, Rakchha Chhetri, Hamish S. Scott, Anna Brown, Christopher N. Hahn, David T. Yeung, Salvia Sajid, Nirmal Robinson, Ranjeny Thomas, Susan Branford, Richard J. D’Andrea, Saumya E. Samaraweera, Mrinal Patnaik, Susanna Proudman, Daniel Thomas, Chung Hoow Kok, Mithun V. Shah, Devendra K. Hiwase
Journal: Blood
Blood (2024) 143 (18): 1873–1877.
https://doi.org/10.1182/blood.2023023593
Published: 2024
Includes: Supplemental data