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Journal Articles

Identifying Stress Granules As Determinants of Leukemia Stem Cell Maintenance and Stress Adaptation

Amanda Tajik, Emily Tsao, Brendon Seale, Soheil Jahangiri, Belma Abidin, Lina Liu, Zaldy Balde, He Tian (Tony) Chen, Nicholas Wong, Ava Keyvani Chahi, Pratik Joshi, Steven Moreira, Curtis W. McCloskey, Shahbaz Khan, Helena Boutzen, Cassandra Wong, Suraj Bansal, Andy G.X. Zeng, Stefan Aigner, Yu Lu, John E. Dick, Thomas Kislinger, Rama Khokha, Mark D. Minden, Gene W. Yeo, Anne-Claude Gingras, Kristin J. Hope
Journal: Blood
Blood (2023) 142 (Supplement 1): 405.
https://doi.org/10.1182/blood-2023-180919
Published: 2023
Journal Articles

Aberrant Splicing of MBD1 Reshapes the Epigenome to Drive Convergent Myeloerythroid Defects in MDS

He Tian (Tony) Tony Chen, Pratik Joshi, Emily Tsao, Joshua Xu, Soheil Jahangiri, Yulin Mo, David Kealy, Dylan Gowlett-Park, Katarina Czibere, Alexandra Misura, Olga Bigun, Renato Sasso, Dianne Chadwick, Sila Usta, Tina Khazaee, Signy Chow, Hubert Tsui, Mark D. Minden, Katherine S Bridge, Gang Zheng, Kristin J. Hope
Journal: Blood
Blood (2023) 142 (Supplement 1): 317.
https://doi.org/10.1182/blood-2023-180889
Published: 2023
Journal Articles

PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal

Ava Keyvani Chahi, Muluken S. Belew, Joshua Xu, He Tian Tony Chen, Stefan Rentas, Veronique Voisin, Gabriela Krivdova, Eric Lechman, Sajid A. Marhon, Daniel D. De Carvalho, John E. Dick, Gary D. Bader, Kristin J. Hope
Journal: Blood
Blood (2022) 140 (9): 992–1008.
https://doi.org/10.1182/blood.2021014698
Published: 2022
Includes: Supplemental data
Journal Articles

PLAGL2 Independently Drives Aberrant Erythropoiesis and Initiation of Preleukemic State

Joshua Xu, Tony Chen, Ava Keyvani Chahi, Gabriela Krivdova, Sajid Marhon, Ana Vujovic, Nicholas Wong, John E. Dick, Kristin Hope
Journal: Blood
Blood (2021) 138 (Supplement 1): 3663.
https://doi.org/10.1182/blood-2021-153098
Published: 2021