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Journal Articles

Very Early/Early Relapses of ALL Show Unexpected Changes of Clonal Markers and High Heterogeneity in Initial and Relapse Treatment Response: ALL-BFM 2000 and ALL-REZ BFM 96/2002 .

Cornelia Eckert, Rolf Koehler, Thomas Flohr, Nikola Hagedorn, Anja Moericke, Martin Stanulla, Renate Kirschner-Schwabe, Gunnar Cario, Arend von Stackelberg, Claus R Bartram, Guenter Henze, Martin Schrappe, Andre Schrauder

Blood (2009) 114 (22): 2612.

https://doi.org/10.1182/blood.V114.22.2612.2612

Published: 2009

Journal Articles

Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray

Norihiko Kawamata, Seishi Ogawa, Martin Zimmermann, Motohiro Kato, Masashi Sanada, Kari Hemminki, Go Yamatomo, Yasuhito Nannya, Rolf Koehler, Thomas Flohr, Carl W. Miller, Jochen Harbott, Wolf-Dieter Ludwig, Martin Stanulla, Martin Schrappe, Claus R. Bartram, H. Phillip Koeffler

Blood (2008) 111 (2): 776–784.

https://doi.org/10.1182/blood-2007-05-088310

Published: 2008

Includes: Supplemental data

Journal Articles

Prognostic Impact of Minimal Residual Disease (MRD) in Children Is Different in B or T Lineage Acute Lymphoblastic Leukemia: Results of Trial AIEOP-BFM ALL 2000.

Blood (2007) 110 (11): 1425.

https://doi.org/10.1182/blood.V110.11.1425.1425

Published: 2007

Journal Articles

Prospective Evaluation of MRD-Kinetics in 274 Children with High-Risk ALL Treated in Trial ALL-BFM 2000: Insights into Development of Resistance and Impact on Further Refinement of Treatment Stratification Strategies.

André Schrauder, MD, Martin Stanulla, MD, Thomas Flohr, PhD, Gunnar Cario, MD, Rolf Köhler, PhD, Renate Panzer-Grümayer, MD, Beat Schäfer, PhD, Martin Zimmermann, PhD, Christina Peters, MD, Claus R. Bartram, MD, Martin Schrappe, MD

Blood (2007) 110 (11): 585.

https://doi.org/10.1182/blood.V110.11.585.585

Published: 2007

Journal Articles

Rearrangement and Deletion of the PAX5 Gene in Pediatric Acute B-Cell Lineage Lymphoblastic Leukemia.

Norihiko Kawamata, MD, Seishi Ogawa, M.D., Martin Zimmermann, Ph.D., Masashi Sanada, M.D., Kari Hemminki, M.D., Go Yamatomo, M.D., Yasuhito Nannya, M.D., Rolf Koehler, Ph.D., Thomas Flohr, Ph.D., Carl W. Miller, Ph.D., Jochen Harbott, M.D., Wolf-Dieter Ludwig, M.D., Martin Stanulla, M.D., Martin Schrappe, M.D., Claus R. Bartram, M.D., Phillip H. Koeffler, M.D.

Blood (2007) 110 (11): 981.

https://doi.org/10.1182/blood.V110.11.981.981

Published: 2007

Journal Articles

Inv(11)(q21q23) Fuses MLL to the NOTCH Co-Activator Mastermind-Like 2 in Secondary T Cell Acute Lymphoblastic Leukemia.

Markus Metzler, Jan Zuna, Martin S. Staege, Lana Harder, Claus Meyer, Thomas Flohr, Joerg Meerpohl, Eva Fronkova, Thorsten Langer, Jochen Harbott, Jan Trka, Reiner Siebert, Rolf Marschalek, Charlotte Marie Niemeyer, Wolfgang Rascher

Blood (2006) 108 (11): 4284.

https://doi.org/10.1182/blood.V108.11.4284.4284

Published: 2006

Journal Articles

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia

Stephen Breit, Martin Stanulla, Thomas Flohr, Martin Schrappe, Wolf-Dieter Ludwig, Gabriele Tolle, Margit Happich, Martina U. Muckenthaler, Andreas E. Kulozik

Blood (2006) 108 (4): 1151–1157.

https://doi.org/10.1182/blood-2005-12-4956

Published: 2006

Includes: Supplemental data

Journal Articles

Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia

Monika Brüggemann, Thorsten Raff, Thomas Flohr, Nicola Gökbuget, Makoto Nakao, Jo Droese, Silke Lüschen, Christiane Pott, Matthias Ritgen, Urban Scheuring, Heinz-August Horst, Eckhard Thiel, Dieter Hoelzer, Claus R. Bartram, Michael Kneba, for the German Multicenter Study Group for Adult Acute Lymphoblastic Leukemia

Blood (2006) 107 (3): 1116–1123.

https://doi.org/10.1182/blood-2005-07-2708

Published: 2006

Journal Articles

Activating NOTCH1 Mutations Are Associated with Good Treatment Response in Childhood T-Cell Acute Lymphoblastic Leukemia.

Stephen Breit, PhD, Martin Stanulla, MD, Thomas Flohr, PhD, Martin Schrappe, MD, Wolf-Dieter Ludwig, MD, Gabriele Tolle, Margit Happich, Martina M. Muckenthaler, PhD, Andreas E. Kulozik, MD, PhD

Blood (2005) 106 (11): 1444.

https://doi.org/10.1182/blood.V106.11.1444.1444

Published: 2005

Journal Articles

MTHFR genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia

Ranjit K. Thirumaran, Andreas Gast, Thomas Flohr, Barbara Burwinkel, Claus Bartram, Kari Hemminki, Rajiv Kumar

Blood (2005) 106 (7): 2590–2591.

https://doi.org/10.1182/blood-2005-04-1719

Published: 2005

Journal Articles

Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia

Gunnar Cario, Martin Stanulla, Bernard M. Fine, Oliver Teuffel, Nils v. Neuhoff, André Schrauder, Thomas Flohr, Beat W. Schäfer, Claus R. Bartram, Karl Welte, Brigitte Schlegelberger, Martin Schrappe

Blood (2005) 105 (2): 821–826.

https://doi.org/10.1182/blood-2004-04-1552

Published: 2005

Includes: Supplemental data

Journal Articles

Thiopurine Methyltransferase Genotype Modulates Early Treatment Response to 6-Mercaptopurine as Measured by Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia.

Martin Stanulla, MD, Elke Schaffeler, PhD, Thomas Flohr, PhD, Gunnar Cario, MD, Karl Welte, MD, Bartram R. Claus, MD, Eichelbaum Michel, MD, Zanger Ulrich, PhD, Schrappe Martin, MD, Schwab Matthias, MD

Blood (2004) 104 (11): 321.

https://doi.org/10.1182/blood.V104.11.321.321

Published: 2004

Journal Articles

Granulocyte colony-stimulating factor receptor mutations in a patient with acute lymphoblastic leukemia secondary to severe congenital neutropenia

Manuela Germeshausen, Matthias Ballmaier, Harald Schulze, Karl Welte, Thomas Flohr, Klaus Beiske, Ingebjørg Storm-Mathisen, Tore G. Abrahamsen

Blood (2001) 97 (3): 829–830.

https://doi.org/10.1182/blood.V97.3.829

Published: 2001

NARROW

Very Early/Early Relapses of ALL Show Unexpected Changes of Clonal Markers and High Heterogeneity in Initial and Relapse Treatment Response: ALL-BFM 2000 and ALL-REZ BFM 96/2002 .

Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray

Prognostic Impact of Minimal Residual Disease (MRD) in Children Is Different in B or T Lineage Acute Lymphoblastic Leukemia: Results of Trial AIEOP-BFM ALL 2000.

Prospective Evaluation of MRD-Kinetics in 274 Children with High-Risk ALL Treated in Trial ALL-BFM 2000: Insights into Development of Resistance and Impact on Further Refinement of Treatment Stratification Strategies.

Rearrangement and Deletion of the PAX5 Gene in Pediatric Acute B-Cell Lineage Lymphoblastic Leukemia.

Inv(11)(q21q23) Fuses MLL to the NOTCH Co-Activator Mastermind-Like 2 in Secondary T Cell Acute Lymphoblastic Leukemia.

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia

Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia

Activating NOTCH1 Mutations Are Associated with Good Treatment Response in Childhood T-Cell Acute Lymphoblastic Leukemia.

MTHFR genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia

Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia

Thiopurine Methyltransferase Genotype Modulates Early Treatment Response to 6-Mercaptopurine as Measured by Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia.

Granulocyte colony-stimulating factor receptor mutations in a patient with acute lymphoblastic leukemia secondary to severe congenital neutropenia

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