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Sofia Bengtzén
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Journal Articles

Resistance to FLT3 Inhibitors in FLT3-Mutated AML Is Associated with CD45RA + CD200 - leukemic Cells and Can be Overcome By Combination with SMAC Mimetics

Nona Struyf, Henrik Gezelius, Anders Lundmark, Chiara Barizza, Hidde Ploeger, Lucía Rico Pizarro, Mattias Vesterlund, Georgios Mermelekas, Albin Osterroos, Anna Bohlin, Sofia Bengtzén, Kerstin Hamberg Levedahl, Rozbeh Jafari, Lukas M Orre, Janne Lehtiö, Päivi Östling, Brinton Seashore-Ludlow, Jessica Nordlund, Soren Lehmann, Olli Kallioniemi, Tom Erkers
Journal: Blood
Blood (2024) 144 (Supplement 1): 1565.
https://doi.org/10.1182/blood-2024-200093
Published: 2024
Journal Articles

Deciphering the Heterogeneity of Acute Myeloid Leukemia through Chromatin Accessibility Profiling

Yotaro Ochi, Markus Liew-Littorin, Yasuhito Nannya, Sofia Bengtzén, Petar Antunovic, Stefan Deneberg, Martin Jadersten, Vladimir Lazarevic, Bertil Uggla, Lovisa Wennström, Emma Olander, Senji Kasahara, Nobuhiro Hiramoto, Nobuhiro Kanemura, Nobuo Sezaki, Maki Sakurada, Makoto Iwasaki, Junya Kanda, Yasunori Ueda, Satoshi Yoshihara, Tom Erkers, Nona Struyf, Masanori Motomura, Masahiro M Nakagawa, Ryunosuke Saiki, Hidehito Fukushima, Koji Okazaki, Akinori Yoda, Rurika Okuda, Guoxiang Xie, Albin Osterroos, Lanying Zhao, Yuichi Shiraishi, Takayuki Ishikawa, Satoru Miyano, Hiroshi I Suzuki, Akifumi Takaori-Kondo, Olli Kallioniemi, Gunnar Juliusson, Martin Höglund, Soren Lehmann, Seishi Ogawa
Journal: Blood
Blood (2024) 144 (Supplement 1): 639.
https://doi.org/10.1182/blood-2024-200415
Published: 2024
Journal Articles

Comparison of Data from Fresh and Frozen AML Samples for Functional Drug Testing

Nona Struyf, Cornelia Arnroth, Stephanie Sunandar, Anna Bohlin, Sofia Bengtzén, Sören Lehmann, Olli Kallioniemi, Päivi Östling, Brinton Seashore-Ludlow, Tom Erkers
Journal: Blood
Blood (2022) 140 (Supplement 1): 6290.
https://doi.org/10.1182/blood-2022-157262
Published: 2022
Journal Articles

Data-Driven Molecular Hallmarks of Acute Myeloid Leukemia: Biological, Prognostic and Therapeutic Implications

Tom Erkers, Francesco Marabita, Nona Struyf, Mattias Vesterlund, Tojo James, Cornelia Arnroth, Anna Bohlin, Sofia Bengtzén, Albin Österroos, Matthias Stahl, Rozbeh Jafari, Lukas Orre, Yudi Pawitan, Brinton Seashore-Ludlow, Janne Lehtiö, Sören Lehmann, Päivi Östling, Olli Kallioniemi
Journal: Blood
Blood (2022) 140 (Supplement 1): 6299.
https://doi.org/10.1182/blood-2022-163046
Published: 2022
Journal Articles

AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding

Huthayfa Mujahed, Sophia Miliara, Anne Neddermeyer, Sofia Bengtzén, Christer Nilsson, Stefan Deneberg, Lina Cordeddu, Karl Ekwall, Andreas Lennartsson, Sören Lehmann
Journal: Blood
Blood (2020) 136 (3): 339–352.
https://doi.org/10.1182/blood.2019002326
Published: 2020
Includes: Supplemental data
Journal Articles

Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks

Stefan Deneberg, Philippe Guardiola, Andreas Lennartsson, Ying Qu, Verena Gaidzik, Odile Blanchet, Mohsen Karimi, Sofia Bengtzén, Hareth Nahi, Bertil Uggla, Ulf Tidefelt, Martin Höglund, Christer Paul, Karl Ekwall, Konstanze Döhner, Sören Lehmann
Journal: Blood
Blood (2011) 118 (20): 5573–5582.
https://doi.org/10.1182/blood-2011-01-332353
Published: 2011
Includes: Supplemental data
Journal Articles

In Vitro and Ex Vivo Studies On Cell Lines and Primary Human Leukemia Cells of the Effects of APR-246 Alone and in Combination with Conventional Chemotherapeutic Drugs.

Kerstin Jonsson-Videsater, Dina Ali, MD, Hareth Nahi, Sofia Bengtzen, Stefan Deneberg, Christer Paul, Professor, Soren Lehmann, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2751.
https://doi.org/10.1182/blood.V114.22.2751.2751
Published: 2009
Journal Articles

Different Incidence and Implications of DNA Hypermethylation in De Novo AML Compared to High-Risk MDS and AML Following MDS.

Stefan Deneberg, Michael Grövdal, Monika Jansson, Verena I. Gaidzik, Andrea Corbacioglu, Hareth Nahi, MD, PhD, Sofia Bengtzen, Konstanze Döhner, Christer Paul, Eva Hellström-Lindberg, Sören Lehmann, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3337.
https://doi.org/10.1182/blood.V112.11.3337.3337
Published: 2008
Journal Articles

Effects of the FLT3 Inhibitor PKC 412 in Combination with Cytostatic Drugs In Vitro in Acute Myeloid Leukemia.

Lars Möllgård, MD PhD, Sofia Bengtzen, Thoas Fioretos, Anna Andersson, Christer Paul, Sören Lehmann, MD PhD
Journal: Blood
Blood (2004) 104 (11): 1810.
https://doi.org/10.1182/blood.V104.11.1810.1810
Published: 2004