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Shirley Uitte de Willige
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Journal Articles

Natural heterogeneity of α2-antiplasmin: functional and clinical consequences

Shiraazkhan Abdul, Frank W. G. Leebeek, Dingeman C. Rijken, Shirley Uitte de Willige
Journal: Blood
Blood (2016) 127 (5): 538–545.
https://doi.org/10.1182/blood-2015-09-670117
Published: 2016
Journal Articles

Fibrinogen γ′ increases the sensitivity to activated protein C in normal and factor V Leiden plasma

Farida Omarova, Shirley Uitte de Willige, Paolo Simioni, Robert A. S. Ariëns, Rogier M. Bertina, Jan Rosing, Elisabetta Castoldi
Journal: Blood
Blood (2014) 124 (9): 1531–1538.
https://doi.org/10.1182/blood-2014-02-554055
Published: 2014
Journal Articles

Gamma Prime Fibrinogen Does Not Cause Arterial Thrombosis

Bethany L Walton, B.S., Todd M Getz, Ph.D., Wolfgang Bergmeier, Ph.D., Shirley Uitte de Willige, Ph.D., Alisa S. Wolberg, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 1092.
https://doi.org/10.1182/blood.V122.21.1092.1092
Published: 2013
Journal Articles

Proteolytic and genetic variation of the alpha-2-antiplasmin C-terminus in myocardial infarction

Shirley Uitte de Willige, Megan Miedzak, Angela M. Carter, Ton Lisman, Frits R. Rosendaal, Peter J. Grant, Helen Philippou, Robert A. S. Ariëns
Journal: Blood
Blood (2011) 117 (24): 6694–6701.
https://doi.org/10.1182/blood-2010-11-320325
Published: 2011
Journal Articles

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

Nicola J. Mutch, Ruchira Engel, Shirley Uitte de Willige, Helen Philippou, Robert A. S. Ariëns
Journal: Blood
Blood (2010) 115 (19): 3980–3988.
https://doi.org/10.1182/blood-2009-11-254029
Published: 2010
Journal Articles

The pleiotropic role of the fibrinogen γ′ chain in hemostasis

Shirley Uitte de Willige, Kristina F. Standeven, Helen Philippou, Robert A. S. Ariëns
Journal: Blood
Blood (2009) 114 (19): 3994–4001.
https://doi.org/10.1182/blood-2009-05-217968
Published: 2009
Journal Articles

Polymorphism 10034C>T Is Located in a Functional Cleavage Stimulation Factor (CstF) Binding Site of the Fibrinogen Gamma Gene and Influences the γ′/γA mRNA Ratio.

Shirley Uitte de Willige, MSc, Inge M. Rietveld, Marieke C.H. de Visser, PhD, Hans L. Vos, PhD, Rogier M. Bertina, PhD
Journal: Blood
Blood (2006) 108 (11): 543.
https://doi.org/10.1182/blood.V108.11.543.543
Published: 2006
Journal Articles

Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen γ′ levels

Clinical Trials & Observations
Shirley Uitte de Willige, Marieke C. H. de Visser, Jeanine J. Houwing-Duistermaat, Frits R. Rosendaal, Hans L. Vos, Rogier M. Bertina
Journal: Blood
Blood (2005) 106 (13): 4176–4183.
https://doi.org/10.1182/blood-2005-05-2180
Published: 2005