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Journal Articles

Partial F8 gene duplication (factor VIII Padua) associated with high factor VIII levels and familial thrombophilia

Paolo Simioni, Stefano Cagnin, Francesca Sartorello, Gabriele Sales, Luca Pagani, Cristiana Bulato, Sabrina Gavasso, Francesca Nuzzo, Francesco Chemello, Claudia M. Radu, Daniela Tormene, Luca Spiezia, Tilman M. Hackeng, Elena Campello, Elisabetta Castoldi

Blood (2021) 137 (17): 2383–2393.

https://doi.org/10.1182/blood.2020008168

Published: 2021

Includes: Supplemental data

Journal Articles

A Plasma-Based Assay to Measure the Susceptibility of Factor V(a) to Inhibition By TFPIα

Tilman M. Hackeng, PhD, Peter van Doorn, MSc, Jan Rosing, PhD, Joost Meijers, PhD, Saskia Middeldorp, MD PhD, Paolo Simioni, MD PhD, Elisabetta Castoldi, PhD

Blood (2018) 132 (Supplement 1): 1168.

https://doi.org/10.1182/blood-2018-99-118767

Published: 2018

Journal Articles

New Functional Assays to Selectively Quantify APC- and TFPI-Cofactor Activities of Protein S in Plasma

Nahla Alshaikh, Msc, Jan Rosing, PhD, Stella Thomassen, Elisabetta Castoldi, PhD, Paolo Simioni, MD PhD, Tilman M. Hackeng, PhD

Blood (2016) 128 (22): 717.

https://doi.org/10.1182/blood.V128.22.717.717

Published: 2016

Journal Articles

Could Hemorrhagic and Thrombotic Risk Due to Peg-Asparaginase be Identified By Coagulative Tests Using Fibtem and Antithrombin Levels? A Single Centre Study

Elena Varotto, Giovanna Sanna, Luca Spiezia, Stefania Varotto, MD, Marta Pillon, MD, Laura Sainati, MD, Alessandra Todesco, Barbara Buldini, MD, Maria Grazia Petris, Raffaella Colombatti, Manuela Tumino, Giada Biddeci, Antonio Marzollo, Maria Gabelli, Maria Paola Boaro, Elena Campello, Paolo Simioni, MD PhD, Giuseppe Basso, Prof, MD, Maria Caterina Putti, MD

Blood (2015) 126 (23): 2305.

https://doi.org/10.1182/blood.V126.23.2305.2305

Published: 2015

Journal Articles

Protein S As a Potential Treatment for FIX-Derived Deep Vein Thrombosis

Vijaya Satish Sekhar Pilli, PhD, Willium Plautz, BS, Rinku Majumder, PhD, Paolo Simioni, MD PhD

Blood (2015) 126 (23): 2277.

https://doi.org/10.1182/blood.V126.23.2277.2277

Published: 2015

Journal Articles

Antithrombin Plasma Levels and Fibtem Determination in Children with Acute Lymphoblastic Leukemia Undergoing Asparaginase Treatment

Giada Biddeci, Giovanna Sanna, Giulia Geranio, Stefania Varotto, MD, Elena Varotto, Maria Gabelli, Mariagrazia Petris, Sara Maggiolo, Elena Campello, Maria Bon, Paolo Simioni, Luca Spiezia, Sartori Maria Teresa, Giuseppe Basso, Maria Caterina Putti

Blood (2014) 124 (21): 5246.

https://doi.org/10.1182/blood.V124.21.5246.5246

Published: 2014

Journal Articles

Fibrinogen γ′ increases the sensitivity to activated protein C in normal and factor V Leiden plasma

Farida Omarova, Shirley Uitte de Willige, Paolo Simioni, Robert A. S. Ariëns, Rogier M. Bertina, Jan Rosing, Elisabetta Castoldi

Blood (2014) 124 (9): 1531–1538.

https://doi.org/10.1182/blood-2014-02-554055

Published: 2014

Journal Articles

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Francesca Nuzzo, Claudia Radu, Marco Baralle, Luca Spiezia, Tilman M. Hackeng, Paolo Simioni, Elisabetta Castoldi

Blood (2013) 122 (23): 3825–3831.

https://doi.org/10.1182/blood-2013-04-499657

Published: 2013

Includes: Supplemental data

Journal Articles

Influence of proband’s characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms

Paolo Bucciarelli, Valerio De Stefano, Serena M. Passamonti, Daniela Tormene, Cristina Legnani, Elena Rossi, Giancarlo Castaman, Paolo Simioni, Michela Cini, Ida Martinelli

Blood (2013) 122 (15): 2555–2561.

https://doi.org/10.1182/blood-2013-05-503649

Published: 2013

Includes: Supplemental data

Journal Articles

The efficacy and the risk of immunogenicity of FIX Padua (R338L) in hemophilia B dogs treated by AAV muscle gene therapy

Jonathan D. Finn, Timothy C. Nichols, Nikolaos Svoronos, Elizabeth P. Merricks, Dwight A. Bellenger, Shangshen Zhou, Paolo Simioni, Katherine A. High, Valder R. Arruda

Blood (2012) 120 (23): 4521–4523.

https://doi.org/10.1182/blood-2012-06-440123

Published: 2012

Journal Articles

Thrombosis risk in purely obstetric APS

Paolo Simioni

Blood (2012) 119 (11): 2435–2436.

https://doi.org/10.1182/blood-2012-01-398735

Published: 2012

Journal Articles

Impact of Persistent Antiphospholipid Antibodies on Symptomatic Thromboembolism In Children: A Systematic Review & Meta-Analysis [Observational Studies]

Gili Kenet, MD, Mariana Bonduel, Anthony Chan, MBBS, FRCPC, FRCPath, Neil Goldenberg, Suzzane Holtzhauer, Alfonso Iorio, Janna M. Journeycake, MD, Ralf Junker, Christoph Male, Mary Patricia Massicotte, MD, Rolf M. Mesters, Paul Monagle, MBBS, MD, MSc, Heleen Van Ommen, Leslie Raffini, MD, Paolo Simioni, Guy Young, MD, Ulrike Nowak-Gottl, MD

Blood (2010) 116 (21): 3169.

https://doi.org/10.1182/blood.V116.21.3169.3169

Published: 2010

Journal Articles

Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms

Connie Duckers, Paolo Simioni, Luca Spiezia, Claudia Radu, Paolo Dabrilli, Sabrina Gavasso, Jan Rosing, Elisabetta Castoldi

Blood (2010) 115 (4): 879–886.

https://doi.org/10.1182/blood-2009-08-237719

Published: 2010

Journal Articles

FIX-R338L (FIX Padua) as a Successful Alternative for the Treatment of Canine Severe Hemophilia B.

Jonathan D Finn, PhD, Paolo Simioni, MD, PhD, Nicholas Iacobelli, B.Sc., Shangzhen Zhou, Timothy C. Nichols, MD, Katherine A. High, MD, Valder R. Arruda, M.D., Ph.D.

Blood (2009) 114 (22): 694.

https://doi.org/10.1182/blood.V114.22.694.694

Published: 2009

Journal Articles

Impact of Thrombophilia On Arterial Ischemic Stroke or Cerebral Venous Sinus Thromboses in Children: A Systematic Review & Meta-Analysis of Observational Studies.

Blood (2009) 114 (22): 3993.

https://doi.org/10.1182/blood.V114.22.3993.3993

Published: 2009

Journal Articles

Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency

Connie Duckers, Paolo Simioni, Luca Spiezia, Claudia Radu, Sabrina Gavasso, Jan Rosing, Elisabetta Castoldi

Blood (2008) 112 (9): 3615–3623.

https://doi.org/10.1182/blood-2008-06-162453

Published: 2008

Journal Articles

Impact of Inherited Thrombophilia on Symptomatic Venous Thrombo-Embolism (VTE) in Children: A Systematic Review & Meta-Analysis of 37 Studies Including 2470 Pediatric Patients.

Guy Young, MD, Frauke Friedrichs, Anthony Chan, MD, Gili Kenet, MD, Paolo Simioni, MD, Helen van Ommen, MD, Anne Krumpel, MD, Marianne Bonduel, MD, Neil Goldenberg, MD, Christophe Male, MD, Manuela Albisetti, MD, Marilyn Manco-Johnson, MD, Leo Brandao, MD, Ulrike Nowak-Gottl, MD

Blood (2007) 110 (11): 3189.

https://doi.org/10.1182/blood.V110.11.3189.3189

Published: 2007

Journal Articles

Isolation and Characterization of an Antifactor VIII Antibody from a Patient with Acquired Hemophilia A and a Severe Hemorrhagic Syndrome.

Michael A. Bukys, BS, Paolo Simioni, MD/Ph.D, Kerri Smith, BS, Luca Spiezia, Michael Kalafatis, Ph.D.

Blood (2006) 108 (11): 4073.

https://doi.org/10.1182/blood.V108.11.4073.4073

Published: 2006

Journal Articles

An underestimated combination of opposites resulting in enhanced thrombotic tendency

Paolo Simioni, Elisabetta Castoldi, Barbara Lunghi, Daniela Tormene, Jan Rosing, Francesco Bernardi

Blood (2005) 106 (7): 2363–2365.

https://doi.org/10.1182/blood-2005-04-1461

Published: 2005

Journal Articles

Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis

Paolo Prandoni, Anthonie W. A. Lensing, Andrea Piccioli, Enrico Bernardi, Paolo Simioni, Bruno Girolami, Antonio Marchiori, Paola Sabbion, Martin H. Prins, Franco Noventa, Antonio Girolami

Blood (2002) 100 (10): 3484–3488.

https://doi.org/10.1182/blood-2002-01-0108

Published: 2002

NARROW

Partial F8 gene duplication (factor VIII Padua) associated with high factor VIII levels and familial thrombophilia

A Plasma-Based Assay to Measure the Susceptibility of Factor V(a) to Inhibition By TFPIα

New Functional Assays to Selectively Quantify APC- and TFPI-Cofactor Activities of Protein S in Plasma

Could Hemorrhagic and Thrombotic Risk Due to Peg-Asparaginase be Identified By Coagulative Tests Using Fibtem and Antithrombin Levels? A Single Centre Study

Protein S As a Potential Treatment for FIX-Derived Deep Vein Thrombosis

Antithrombin Plasma Levels and Fibtem Determination in Children with Acute Lymphoblastic Leukemia Undergoing Asparaginase Treatment

Fibrinogen γ′ increases the sensitivity to activated protein C in normal and factor V Leiden plasma

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Influence of proband’s characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms

The efficacy and the risk of immunogenicity of FIX Padua (R338L) in hemophilia B dogs treated by AAV muscle gene therapy

Thrombosis risk in purely obstetric APS

Impact of Persistent Antiphospholipid Antibodies on Symptomatic Thromboembolism In Children: A Systematic Review & Meta-Analysis [Observational Studies]

Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms

FIX-R338L (FIX Padua) as a Successful Alternative for the Treatment of Canine Severe Hemophilia B.

Impact of Thrombophilia On Arterial Ischemic Stroke or Cerebral Venous Sinus Thromboses in Children: A Systematic Review & Meta-Analysis of Observational Studies.

Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency

Impact of Inherited Thrombophilia on Symptomatic Venous Thrombo-Embolism (VTE) in Children: A Systematic Review & Meta-Analysis of 37 Studies Including 2470 Pediatric Patients.

Isolation and Characterization of an Antifactor VIII Antibody from a Patient with Acquired Hemophilia A and a Severe Hemorrhagic Syndrome.

An underestimated combination of opposites resulting in enhanced thrombotic tendency

Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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