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Journal Articles

Escape from Type II JAK2 Inhibition in MPN Depends on AXL/MAPK Activation and Is Targetable

Tamara Codilupi, Jakub Szybinski, Sime Brkic, Simona Stivala, Julie Yang, Nilabh Ghosh, Katarzyna Buczak, Jakob Passweg, Anne Angelillo-Scherrer, Stefan Dirnhofer, Ross L. Levine, Richard Koche, Sara C. Meyer

Blood (2022) 140 (Supplement 1): 3850–3851.

https://doi.org/10.1182/blood-2022-159068

Published: 2022

Journal Articles

MPN patients with low mutant JAK2 allele burden show late expansion restricted to erythroid and megakaryocytic lineages

Ronny Nienhold, Peter Ashcroft, Jakub Zmajkovic, Shivam Rai, Tata Nageswara Rao, Beatrice Drexler, Sara C. Meyer, Pontus Lundberg, Jakob R. Passweg, Danijela Leković, Vladan Čokić, Sebastian Bonhoeffer, Radek C. Skoda

Blood (2020) 136 (22): 2591–2595.

https://doi.org/10.1182/blood.2019002943

Published: 2020

Includes: Supplemental data

Journal Articles

Targeting Cell Non-Autonomous MAPK Activation As a Novel Therapeutic Strategy in Myeloproliferative Neoplasms

Sara C. Meyer, MD PhD, Nilabh Ghosh, MSc, Simona Stivala, PhD, Anne Baerenwaldt, PhD, Hui Hao-Shen, Stefan Dirnhofer, MD, Matthias S. Dettmer, MD, Cédric Simillion, PhD, Sophia Chiu, MSc, Matthew Keller, MSc, Maria Kleppe, PhD, Morgane Hilpert, PhD, Andreas S. Buser, MD, Jakob R. Passweg, MDMS, Thomas Radimerski, PhD, Radek C. Skoda, MD, Ross L. Levine, MD

Blood (2017) 130 (Supplement 1): 381.

https://doi.org/10.1182/blood.V130.Suppl_1.381.381

Published: 2017

Journal Articles

JAK2 exon 12 mutant mice display isolated erythrocytosis and changes in iron metabolism favoring increased erythropoiesis

Jean Grisouard, Sai Li, Lucia Kubovcakova, Tata Nageswara Rao, Sara C. Meyer, Pontus Lundberg, Hui Hao-Shen, Vincent Romanet, Masato Murakami, Thomas Radimerski, Stephan Dirnhofer, Radek C. Skoda

Blood (2016) 128 (6): 839–851.

https://doi.org/10.1182/blood-2015-12-689216

Published: 2016

Includes: Supplemental data

Journal Articles

The Intercept Blood System Affects Platelet Function and Survival By Inducing Apoptosis

Simona Stivala, PhD, Sara Gobbato, M.Sc., Martin F Reiner, MD, Sara C Meyer, MDPhD, Thomas F Lüscher, MD, Laura Infanti, Andreas S. Buser, MD, Juerg H. Beer, MD

Blood (2014) 124 (21): 4283.

https://doi.org/10.1182/blood.V124.21.4283.4283

Published: 2014

Journal Articles

Type II Inhibition of JAK2 with NVP-CHZ868 Reverses Type I JAK Inhibitor Persistence and Demonstrates Increased Efficacy in MPN Models

Sara C Meyer, MD PhD, Matthew D Keller, BS, Priya Koppikar, PhD, Olga A Guryanova, MD PhD, Maria Kleppe, PhD, Anna Sophia McKenney, MPH, William R Sellers, MD, Francesco Hofmann, PhD, Fabienne Baffert, Christoph Gaul, PhD, Thomas Radimerski, PhD, Ross L Levine, MD

Blood (2014) 124 (21): 160.

https://doi.org/10.1182/blood.V124.21.160.160

Published: 2014

Journal Articles

Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis

Sara C. Meyer, Matthew D. Keller, Brittany A. Woods, Lindsay M. LaFave, Lennart Bastian, Maria Kleppe, Neha Bhagwat, Sachie Marubayashi, Ross L. Levine

Blood (2014) 124 (14): 2280–2284.

https://doi.org/10.1182/blood-2014-03-560441

Published: 2014

Includes: Supplemental data

Journal Articles

Addition of Omega-3 α-Linolenic Acid to Platelet Apheresis Units Preserves Platelet Activatability Over Time and Reduces Baseline Activation Under Routine Storage Conditions: A Pilot Study

Simona Stivala, Ph.D., Sara C Meyer, MD PhD, Martin Reiner, MD, Thomas F. Luscher, MD, Andreas S. Buser, MD, Juerg H. Beer, MD

Blood (2012) 120 (21): 3433.

https://doi.org/10.1182/blood.V120.21.3433.3433

Published: 2012

Journal Articles

Prognostic Impact of Iron Overload During Follow-up After Allogeneic Stem Cell Transplantation

Sara C. Meyer, MD, PhD, Andreas S. Buser, MD, André Tichelli, MD, Jakob R. Passweg, MD, Martin Stern, MD

Blood (2011) 118 (21): 347.

https://doi.org/10.1182/blood.V118.21.347.347

Published: 2011

Journal Articles

Management Strategies of Stroke and Acute Coronary Syndrome In Von Willebrand Disease and Hemophilia: Experience From a Case Series and a Swiss Survey of Frequencies.

Sara C. Meyer, MD, PhD, Elina Armstrong, MD, PhD, Christine Perdrizat, Hans-Rudolf Schmid, PhD, Riitta Lassila, MD, PhD, Juerg H. Beer, MD

Blood (2010) 116 (21): 1406.

https://doi.org/10.1182/blood.V116.21.1406.1406

Published: 2010

Journal Articles

Characterization of Five Homozygous ADAMTS13 Mutations in Hereditary Thrombotic Thrombocytopenic Purpura – Towards a Phenotype-Genotype Correlation?

Sara C Meyer, Shengyu Jin, Wenjing Cao, X. Long Zheng, Bernhard Lammle, Johanna A Kremer Hovinga

Blood (2008) 112 (11): 274.

https://doi.org/10.1182/blood.V112.11.274.274

Published: 2008

Journal Articles

The ADAMTS13 Gene as the Immunological Culprit in Acute Acquired TTP - First Evidence of Genetic Out-Breeding Depression in Humans.

Sara C. Meyer, MD, Carlo R. Largiader, PhD, Shengyu Jin, MD, PhD, X. Long Zheng, MD, PhD, Clemens A. Dahinden, MD, James N. George, MD, Bernhard Lammle, MD, Johanna A. Kremer Hovinga, MD

Blood (2007) 110 (11): 277.

https://doi.org/10.1182/blood.V110.11.277.277

Published: 2007

NARROW

Escape from Type II JAK2 Inhibition in MPN Depends on AXL/MAPK Activation and Is Targetable

MPN patients with low mutant JAK2 allele burden show late expansion restricted to erythroid and megakaryocytic lineages

Targeting Cell Non-Autonomous MAPK Activation As a Novel Therapeutic Strategy in Myeloproliferative Neoplasms

JAK2 exon 12 mutant mice display isolated erythrocytosis and changes in iron metabolism favoring increased erythropoiesis

The Intercept Blood System Affects Platelet Function and Survival By Inducing Apoptosis

Type II Inhibition of JAK2 with NVP-CHZ868 Reverses Type I JAK Inhibitor Persistence and Demonstrates Increased Efficacy in MPN Models

Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis

Addition of Omega-3 α-Linolenic Acid to Platelet Apheresis Units Preserves Platelet Activatability Over Time and Reduces Baseline Activation Under Routine Storage Conditions: A Pilot Study

Prognostic Impact of Iron Overload During Follow-up After Allogeneic Stem Cell Transplantation

Management Strategies of Stroke and Acute Coronary Syndrome In Von Willebrand Disease and Hemophilia: Experience From a Case Series and a Swiss Survey of Frequencies.

Characterization of Five Homozygous ADAMTS13 Mutations in Hereditary Thrombotic Thrombocytopenic Purpura – Towards a Phenotype-Genotype Correlation?

The ADAMTS13 Gene as the Immunological Culprit in Acute Acquired TTP - First Evidence of Genetic Out-Breeding Depression in Humans.

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American Society of Hematology

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American Society of Hematology

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