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Journal Articles

RAS/RAF landscape in monoclonal plasma cell conditions.

Anaïs Schavgoulidze, Jill Corre, Mehmet K. Samur, Celine Mazzotti, Luka Pavageau, Aurore Perrot, Titouan Cazaubiel, Xavier Leleu, Margaret Macro, Dr, Karim Belhadj, Murielle Roussel, Sabine Brechignac, Lydia Montes, Jr, Denis Caillot, Laurent Frenzel, Philippe Rey, Jean Marc Schiano, Thomas Chalopin, Caroline Jacquet, Valentine Richez, Frederique Orsini Piocelle, Jean Fontan, Salomon Manier, Ludovic Martinet, Adam Sciambi, Mohamad Mohty, Hervé Avet-Loiseau
Journal: Blood
Blood blood.2023022295.
https://doi.org/10.1182/blood.2023022295
Published: 2024
Includes: Supplemental data
Journal Articles

Treatment of Adverse-Risk and Refractory/Relapsed Acute Myeloid Leukemia (AML) Patients with FLAG-IDA ± Venetoclax and CLAG-M: A Monocentric Experience

Ramy Rahmé, Valérie Vidal, Thomas Hueso, Lucie Le Meur, Marthe Rigal, Sarah Ivanoff, Sabine Brechignac, Regis Peffault De Latour, Claude Gardin, Thorsten Braun
Journal: Blood
Blood (2023) 142 (Supplement 1): 1520.
https://doi.org/10.1182/blood-2023-174356
Published: 2023
Journal Articles

Biallelic deletion of 1p32 defines ultra-high-risk myeloma, but monoallelic del(1p32) remains a strong prognostic factor

CME Clinical Trials & Observations
Anaïs Schavgoulidze, Alexis Talbot, Aurore Perrot, Titouan Cazaubiel, Xavier Leleu, Salomon Manier, Laure Buisson, Sabrina Mahéo, Laura Do Souto Ferreira, Luka Pavageau, Cyrille Hulin, Jean-Pierre Marolleau, Laurent Voillat, Karim Belhadj, Marion Divoux, Borhane Slama, Sabine Brechignac, Margaret Macro, Anne-Marie Stoppa, Laurence Sanhes, Frédérique Orsini-Piocelle, Jean Fontan, Marie-Lorraine Chretien, Hélène Demarquette, Mohamad Mohty, Hervé Avet-Loiseau, Jill Corre
Journal: Blood
Blood (2023) 141 (11): 1308–1315.
https://doi.org/10.1182/blood.2022017863
Published: 2023
Includes: Supplemental data
Journal Articles

Bortezomib and high-dose melphalan conditioning regimen in frontline multiple myeloma: an IFM randomized phase 3 study

Clinical Trials & Observations
Murielle Roussel, Valérie Lauwers-Cances, Margaret Macro, Xavier Leleu, Bruno Royer, Cyrille Hulin, Lionel Karlin, Aurore Perrot, Cyrille Touzeau, Marie-Lorraine Chrétien, Sophie Rigaudeau, Mamoun Dib, Emmanuelle Nicolas-Virelizier, Martine Escoffre-Barbe, Karim Belhadj, Clara Mariette, Anne-Marie Stoppa, Carla Araujo, Chantal Doyen, Jean Fontan, Brigitte Kolb, Laurent Garderet, Sabine Brechignac, Jean-Valère Malfuson, Arnaud Jaccard, Pascal Lenain, Cécile Borel, Benjamin Hebraud, Omar Benbrahim, Véronique Dorvaux, Salomon Manier, Karine Augeul-Meunier, Marie-Christiane Vekemans, Edouard Randriamalala, Driss Chaoui, Jo Caers, Carine Chaleteix, Lofti Benboubker, Laure Vincent, Sylvie Glaisner, Patricia Zunic, Borhane Slama, Jean-Richard Eveillard, Catherine Humbrecht-Kraut, Véronique Morel, Philippe Mineur, Jean-Claude Eisenmann, Hélène Demarquette, Valentine Richez, Marguerite Vignon, Denis Caillot, Thierry Facon, Philippe Moreau, Anne-Laurène Colin, Pascale Olivier, Soraya Wuilleme, Hervé Avet-Loiseau, Jill Corre, Michel Attal
Journal: Blood
Blood (2022) 139 (18): 2747–2757.
https://doi.org/10.1182/blood.2021014635
Published: 2022
Includes: Supplemental data
Journal Articles

Primary plasma cell leukemias displaying t(11;14) have specific genomic, transcriptional, and clinical features

Brief Report
Titouan Cazaubiel, Xavier Leleu, Aurore Perrot, Salomon Manier, Laure Buisson, Sabrina Maheo, Laura Do Souto Ferreira, Romain Lannes, Luka Pavageau, Cyrille Hulin, Jean-Pierre Marolleau, Laurent Voillat, Karim Belhadj, Marion Divoux, Borhane Slama, Sabine Brechignac, Margaret Macro, Anne-Marie Stoppa, Laurence Sanhes, Frédérique Orsini-Piocelle, Jean Fontan, Marie-Lorraine Chretien, Hélène Demarquette, Mohamad Mohty, Anais Schavgoulidze, Herve Avet-Loiseau, Jill Corre
Journal: Blood
Blood (2022) 139 (17): 2666–2672.
https://doi.org/10.1182/blood.2021014968
Published: 2022
Includes: Supplemental data
Journal Articles

Ixazomib and Daratumumab without Dexamethasone (I-Dara) in Elderly Frail RRMM Patients. a Multicenter Phase 2 Study (IFM 2018-02) of the Intergroupe Francophone Du Myélome (IFM)

Magaret Macro, Cyrille Touzeau, Clara Mariette, Salomon Manier, Sabine Brechignac, Laure Vincent, Benjamin Hebraud, Olivier Decaux, Samantha Schulmann, Caroline Bureau Lenoir, Pascal Godmer, Jean-Jacques Parienti, Xavier Leleu
Journal: Blood
Blood (2021) 138 (Supplement 1): 83.
https://doi.org/10.1182/blood-2021-148152
Published: 2021
Journal Articles

In Multiple Myeloma, High-Risk Secondary Genetic Events Observed at Relapse Are Present from the Diagnosis in Tiny Undetectable Subclones

Herve Avet-Loiseau, Romain Lannes, Aurore Perrot, Céline Mazzotti, Marion Divoux, Titouan Cazaubiel, Xavier Leleu, Anaïs Schavgoulidze, Marie-Lorraine Chretien, Salomon Manier, Didier Adiko, Frédérique Orsini-Piocelle, Francois Lifermann, Sabine Brechignac, Lauris Gastaud, Didier Bouscary, Magaret Macro, Mohamad Mohty, Nikhil C. Munshi, Jill Corre
Journal: Blood
Blood (2021) 138 (Supplement 1): 77.
https://doi.org/10.1182/blood-2021-146869
Published: 2021
Journal Articles

Phase II Study of the Combination of Pomalidomide with Dexamethasone As Maintenance Therapy after First Relapse Treatment with PCD Followed or Not By Autologous Stem Cell Transplant in Multiple Myeloma Patients

Laurent Garderet, Frédérique Kuhnowski, Benoit Berge, Murielle Roussel, Martine Escoffre-Barbe, Ingrid Lafon, Thierry Facon, Xavier Leleu, Lionel Karlin, Aurore Perrot, Philippe Moreau, Gerald Marit, Anne-Marie Stoppa, Bruno Royer, Carine Chaleteix, Mourad Tiab, Carla Araujo, Pascal Lenain, Margaret Macro, Eric G. Voog, Lotfi Benboubker, Olivier Thierry Allangba, Eric Jourdan, Frédérique Orsini-Piocelle, Sabine Brechignac, Jean-Richard Eveillard, Karim Belhadj, Marc Wetterwald, Brigitte Pegourie, Arnaud Jaccard, Jean Claude Eisenmann, Sylvie Glaisner, Mohamad Mohty, Cyrille Hulin, Herve Avet Loiseau, Claire Mathiot, Michel Attal
Journal: Blood
Blood (2021) 138 (Supplement 1): 2753.
https://doi.org/10.1182/blood-2021-152136
Published: 2021
Journal Articles

del(17p) without TP53 mutation confers a poor prognosis in intensively treated newly diagnosed patients with multiple myeloma

Clinical Trials & Observations Brief Report
Jill Corre, Aurore Perrot, Denis Caillot, Karim Belhadj, Cyrille Hulin, Xavier Leleu, Mohamad Mohty, Thierry Facon, Laure Buisson, Laura Do Souto, Romain Lannes, Stephanie Dufrechou, Naïs Prade, Frederique Orsini-Piocelle, Laurent Voillat, Arnaud Jaccard, Lionel Karlin, Margaret Macro, Sabine Brechignac, Mamoun Dib, Laurence Sanhes, Jean Fontan, Lauriane Clement-Filliatre, Jean-Pierre Marolleau, Stephane Minvielle, Philippe Moreau, Hervé Avet-Loiseau
Journal: Blood
Blood (2021) 137 (9): 1192–1195.
https://doi.org/10.1182/blood.2020008346
Published: 2021
Includes: Supplemental data
Journal Articles

Pomalidomide, cyclophosphamide, and dexamethasone for relapsed multiple myeloma

Clinical Trials & Observations
Laurent Garderet, Frederique Kuhnowski, Benoit Berge, Murielle Roussel, Martine Escoffre-Barbe, Ingrid Lafon, Thierry Facon, Xavier Leleu, Lionel Karlin, Aurore Perrot, Philippe Moreau, Gerald Marit, Anne-Marie Stoppa, Bruno Royer, Carine Chaleteix, Mourad Tiab, Carla Araujo, Pascal Lenain, Margaret Macro, Eric Voog, Lofti Benboubker, Olivier Allangba, Eric Jourdan, Frederique Orsini-Piocelle, Sabine Brechignac, Jean-Richard Eveillard, Karim Belhadj, Marc Wetterwald, Brigitte Pegourie, Arnaud Jaccard, Jean-Claude Eisenmann, Sylvie Glaisner, Mohamad Mohty, Cyrille Hulin, Herve Avet Loiseau, Claire Mathiot, Michel Attal
Journal: Blood
Blood (2018) 132 (24): 2555–2563.
https://doi.org/10.1182/blood-2018-07-863829
Published: 2018
Includes: Supplemental data
Journal Articles

Minimal residual disease negativity using deep sequencing is a major prognostic factor in multiple myeloma

Clinical Trials & Observations
Aurore Perrot, Valerie Lauwers-Cances, Jill Corre, Nelly Robillard, Cyrille Hulin, Marie-Lorraine Chretien, Thomas Dejoie, Sabrina Maheo, Anne-Marie Stoppa, Brigitte Pegourie, Lionel Karlin, Laurent Garderet, Bertrand Arnulf, Chantal Doyen, Nathalie Meuleman, Bruno Royer, Jean-Richard Eveillard, Lotfi Benboubker, Mamoun Dib, Olivier Decaux, Arnaud Jaccard, Karim Belhadj, Sabine Brechignac, Brigitte Kolb, Cecile Fohrer, Mohamad Mohty, Margaret Macro, Paul G. Richardson, Victoria Carlton, Martin Moorhead, Tom Willis, Malek Faham, Kenneth C. Anderson, Jean-Luc Harousseau, Xavier Leleu, Thierry Facon, Philippe Moreau, Michel Attal, Hervé Avet-Loiseau, Nikhil Munshi
Journal: Blood
Blood (2018) 132 (23): 2456–2464.
https://doi.org/10.1182/blood-2018-06-858613
Published: 2018
Includes: Supplemental data
Journal Articles

A Single Center Experience of Cladribine, Cytarabine, Filgrastim and Mitoxantrone (CLAG-M regimen) in High-Risk or Relapsed/Refractory, Acute Myeloid Leukemia (AML)

Valérie Vidal, Laila Hamri, Alice Marceau-Renaut, Flore Sicre De Fontbrune, MD PhD, Virginie Eclache, Nevine Osman, Benjamin Papoular, Daniel Lusina, Sabine Brechignac, Regis Peffault De Latour, Claude Preudhomme, Claude Gardin, Thorsten Braun, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4007.
https://doi.org/10.1182/blood-2018-99-117237
Published: 2018
Journal Articles

Bortezomib and High-Dose Melphalan Vs. High-Dose Melphalan As Conditioning Regimen before Autologous Stem Cell Transplantation in De Novo Multiple Myeloma Patients: A Phase 3 Study of the Intergroupe Francophone Du Myelome (IFM 2014-02)

Murielle Roussel, Benjamin Hebraud, MD, Valerie Lauwers-Cances, MD, Margaret Macro, MD, Xavier Leleu, MD PhD, Cyrille Hulin, MD, Lionel Karlin, MD, Bruno Royer, MD, Aurore Perrot, MD, Philippe Moreau, MDPhD, Denis Caillot, MD, Sophie Rigaudeau, MD, Mamoun Dib, MD, Emmanuelle Nicolas-Virelizier, MD, Martine Escoffre-Barbe, MD, Karim Belhadj, MD, Brigitte Pegourie, MD, Anne-Marie Stoppa, MD, Carla Araujo, MD, Chantal Doyen, MD, Jean Fontan, MD, Brigitte Kolb, MD, Laurent Garderet, MD PhD, Sabine Brechignac, MD, Jean Valere Malfuson, MD, Veronique Dorvaux, MD, Pascal Lenain, MD, Omar Benbrahim, MD, Arnaud Jaccard, Cecile Borel, MD, Herve Avet Loiseau, MD PhD, Michel Attal, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 398.
https://doi.org/10.1182/blood.V130.Suppl_1.398.398
Published: 2017
Journal Articles

Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma

CME
Thomas Dejoie, Jill Corre, Helene Caillon, Cyrille Hulin, Aurore Perrot, Denis Caillot, Eileen Boyle, Marie-Lorraine Chretien, Jean Fontan, Karim Belhadj, Sabine Brechignac, Olivier Decaux, Laurent Voillat, Philippe Rodon, Olivier Fitoussi, Carla Araujo, Lotfi Benboubker, Charlotte Fontan, Mourad Tiab, Pascal Godmer, Odile Luycx, Olivier Allangba, Jean-Michel Pignon, Jean-Gabriel Fuzibet, Laurence Legros, Anne Marie Stoppa, Mamoun Dib, Brigitte Pegourie, Frederique Orsini-Piocelle, Lionel Karlin, Bertrand Arnulf, Murielle Roussel, Laurent Garderet, Mohamad Mohty, Nathalie Meuleman, Chantal Doyen, Pascal Lenain, Margaret Macro, Xavier Leleu, Thierry Facon, Philippe Moreau, Michel Attal, Herve Avet-Loiseau
Journal: Blood
Blood (2016) 128 (25): 2941–2948.
https://doi.org/10.1182/blood-2016-07-726778
Published: 2016
Journal Articles

Daratumumab in Combination with Dexamethasone in Resistant or Refractory Multiple Myeloma: Primary Results of the IFM2014-04 Trial

Eileen Mary Boyle, MD MSc, Marie-Odile Petillon, MD, Charles Herbaux, MD, Johanna Mimouni, Xavier Leleu, Lionel Karlin, MD, Chantal Doyen, MD, Marc Wetterwald, MD PhD, Muriel Roussel, MD, Cyrille Hulin, Bruno Royer, MD, Margaret Macro, Philippe Moreau, Karel Fostier, MD, Mamoun Dib, Sabine Brechignac, MD, Caroline Bureau, Gerald Marit, MD, Adrian Tempescul, MD, Marie Lorraine Chretien, Charles Zarnitsky, Cecile Fohrer, MD, Aurore Perrot, MD, Lotfi Benboubker, MD PhD, Laurent Voillat, Jean Valere Malfuson, Clara Mariette, Mourad Tiab, Sophie Rigaudeau, Arnaud Jaccard, MD PhD, Anne-Marie Stoppa, Laure Vincent, Jean Claude Eisenmann, MD, Laurent Frenzel, Bertrand Arnulf, MD, Mohamad Mohty, MD PhD, Philippe Rodon, MD, Brigitte Kolb, Olivier Decaux, MD PhD, Pascal Godmer, David Beauvais, Benjamin Carpentier, Sarah Bonnet, MD, Thomas Longval, Mathieu Dewevre, Herve Avet-Loiseau, MD PhD, Michel Attal, Susanna Schraen, PharmD, Thierry Facon
Journal: Blood
Blood (2016) 128 (22): 2138.
https://doi.org/10.1182/blood.V128.22.2138.2138
Published: 2016
Journal Articles

Long Term Follow-up of Hematopoietic Stem Cell Transplantation (HSCT) for Primary Plasma Cell Leukemia (pPCL): Final Results of a Prospective Study of IFM Group

Bruno Royer, MD, Momar Diouf, Murielle Roussel, Lionel Karlin, MD, Cyrille Hulin, Bertrand Arnulf, MD, Margaret Macro, Sylvie Cailleres, Annie Brion, MD, Sabine Brechignac, MD, Karim Belhadj, MD, Marie Lorraine Chretien, Marc Wetterwald, MD PhD, Carine Chaleteix, Mourad Tiab, Xavier Leleu, Laurent Frenzel, Laurent Garderet, MD, Sylvain Choquet, MD, jean Gabriel Fuzibet, Charles Dauriac, MD, luc-Matthieu Fornecker, Lotfi Benboubker, MD PhD, Thierry Facon, MD, Philippe Moreau, Herve Avet Loiseau, MD PhD, Stephane Minvielle, Jean Pierre Marolleau, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4612.
https://doi.org/10.1182/blood.V128.22.4612.4612
Published: 2016
Journal Articles

VTD is superior to VCD prior to intensive therapy in multiple myeloma: results of the prospective IFM2013-04 trial

Clinical Trials & Observations
Philippe Moreau, Cyrille Hulin, Margaret Macro, Denis Caillot, Carine Chaleteix, Murielle Roussel, Laurent Garderet, Bruno Royer, Sabine Brechignac, Mourad Tiab, Mathieu Puyade, Martine Escoffre, Anne-Marie Stoppa, Thierry Facon, Brigitte Pegourie, Driss Chaoui, Arnaud Jaccard, Borhane Slama, Gerald Marit, Karim Laribi, Pascal Godmer, Odile Luycx, Jean-Claude Eisenmann, Olivier Allangba, Mamoun Dib, Carla Araujo, Jean Fontan, Karim Belhadj, Marc Wetterwald, Véronique Dorvaux, Jean-Paul Fermand, Philippe Rodon, Brigitte Kolb, Sylvie Glaisner, Jean-Valere Malfuson, Pascal Lenain, Laetitia Biron, Lucie Planche, Helene Caillon, Herve Avet-Loiseau, Thomas Dejoie, Michel Attal
Journal: Blood
Blood (2016) 127 (21): 2569–2574.
https://doi.org/10.1182/blood-2016-01-693580
Published: 2016
Journal Articles

Evaluation of Minimal Residual Disease (MRD) By Next Generation Sequencing (NGS) Is Highly Predictive of Progression Free Survival in the IFM/DFCI 2009 Trial

Herve Avet-Loiseau, MD PhD, Jill Corre, Valerie Lauwers-Cances, MD, Marie-Lorraine Chretien, Nelly Robillard, Engineer, Xavier Leleu, MD PhD, Cyrille Hulin, MD, Catherine Gentil, Engineer, Bertrand Arnulf, Karim Belhadj, MD, Sabine Brechignac, MD, Laurent Garderet, MD, Lionel Karlin, Gerald Marit, Lotfi Benboubker, Frederique Orsini-Piocelle, MD, Bruno Royer, MD, Bernard Drenou, MD, Mourad Tiab, MD, Thierry Lamy, MD PhD, Margaret MACRO, MD, Paul G. Richardson, MD, Kenneth C Anderson, MD, Malek Faham, MD PhD, Thierry Facon, Philippe Moreau, Michel Attal, Nikhil C. Munshi, MD
Journal: Blood
Blood (2015) 126 (23): 191.
https://doi.org/10.1182/blood.V126.23.191.191
Published: 2015
Journal Articles

Bortezomib, Thalidomide and Dexamethasone (VTD) Is Superior to Bortezomib, Cyclophosphamide and Dexamethasone (VCD) Prior to Autologous Stem Cell Transplantation for Patients with De Novo Multiple Myeloma. Results of the Prospective IFM 2013-04 Trial

Philippe Moreau, Cyrille Hulin, Margaret MACRO, MD, Denis Caillot, Carine Chaleteix, Murielle Roussel, Laurent Garderet, MD, Bruno Royer, MD, Sabine Brechignac, MD, Mourad Tiab, MD, Mathieu Puyade, MD, Martine Escoffre, Anne-Marie Stoppa, MD, Thierry Facon, Brigitte Pégourie, Driss Chaoui, MD, Arnaud Jaccard, MD PhD, Borhane Slama, Gerald Marit, Kamel Laribi, Pascal Godmer, MD, Odile Luycx, Jean Claude Eisenmann, MD, Olivier Allangha, Sylvie Glaisner, Mamoun Dib, Carla Araujo, Jean Fontan, Karim Belhadj, MD, Marc Wetterwald, MD PhD, Veronique Dorvaux, Jean-Paul Fermand, Philippe Rodon, MD, Brigitte Kolb, Pascal Lenain, MD, Lucie Planche, Laetitia Biron, Helene Caillon, Herve Avet-Loiseau, Thomas Dejoie, Michel Attal
Journal: Blood
Blood (2015) 126 (23): 393.
https://doi.org/10.1182/blood.V126.23.393.393
Published: 2015
Journal Articles

Salvage Therapy Post Pomalidomide-Based Regimen in Relapsed/Refractory Myeloma

Guillemette Fouquet, Lionel Karlin, Margaret MACRO, MD, Denis Caillot, Murielle Roussel, Bertrand Arnulf, Brigitte Pégourie, Marie-Odile Petillon, Gerald Marit, Claire Mathiot, MD, Brigitte Kolb, Anne-Marie Stoppa, MD, Sabine Brechignac, MD, Philippe Rodon, MD, Mamoun Dib, Mourad Tiab, MD, Laurence Legros, MD, Anne Banos, MD, Marc Wetterwald, MD PhD, Laurent Garderet, MD, Bruno Royer, MD, Cyrille Hulin, Lotfi Benboubker, Olivier Decaux, MD PhD, Martine Escoffre, Jean-Paul Fermand, Philippe Moreau, Herve Avet-Loiseau, MD PhD, Michel Attal, Thierry Facon, Xavier Leleu, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1831.
https://doi.org/10.1182/blood.V126.23.1831.1831
Published: 2015