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Robert Z Orlowski
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Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney D. DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z. Orlowski, Muzaffar H. Qazilbash, Kapil N. Bhalla, Simona Colla, Hagop M. Kantarjian, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Daisuke Nakada, Jeffrey J. Molldrem, Gheath Alatrash, Andrew Futreal, Elizabeth J. Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 346.
https://doi.org/10.1182/blood-2024-208106
Published: 2024
Journal Articles

Health-Related Quality of Life (HRQoL) in Patients with Newly Diagnosed Multiple Myeloma (NDMM) Ineligible for Transplantation and Treated with Isatuximab, Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRd) Vs. Vrd Alone: Results from the Imroz Study

Meletios Dimopoulos, Thierry Facon, Meral Beksac, Ludek Pour, Roman Hajek, Zhuogang Liu, Jiri Minarik, Philippe Moreau, Joanna Romejko-Jarosinska, Ivan Špička, Vladimir I. Vorobyev, Britta Besemer, Tadao Ishida, Wojciech Janowski, Sevgi Kalayoglu Besisik, Gurdeep Parmar, Pawel Robak, Elena Zamagni, Hartmut Goldschmidt, Thomas Martin, Salomon Manier, Mohamad Mohty, Robert Z. Orlowski, Erin Comerford, Claire Tian, Jérôme Msihid, Feng Lin, Stephanie Rhoten, Xavier. P Leleu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3352.
https://doi.org/10.1182/blood-2024-207087
Published: 2024
Journal Articles

Multi-Omic Single-Cell Characterization of Paired and Serial Samples in Responding and Non-Responding Patients Receiving BCMA Bispecific Antibody Therapy for Multiple Myeloma

Minghao Dang, Hans C. Lee, Hima Bansal, Maria Jose Acevedo-Calado, Li Qin, Wei Tan, Luz Yurany Moreno Rueda, David Berrios, Oren Pasvolsky, Mahmoud R. Gaballa, Melody R. Becnel, J Christine Ye, Krina K. Patel, Pei Lin, Sheeba K. Thomas, Donna M. Weber, Linghua Wang, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 3272.
https://doi.org/10.1182/blood-2024-210080
Published: 2024
Journal Articles

Characterization of the Tumor Microenvironment of Diagnostic Bone Marrow Core Biopsies from African American Multiple Myeloma Patients Using Imaging Mass Cytometry

Anthony Colombo, Esther Lam, Ben Falk, Anton Luis Villamejor, Amie Hwang, Jose Aparicio, Jia Yin Wan, Chun R. Chao, Mallory Bernstein, Ravi Vij, Mark Fiala, Pei Lin, Robert Z. Orlowski, Imran Siddiqi, David Conti, Akil Merchant, Wendy Cozen
Journal: Blood
Blood (2024) 144 (Supplement 1): 3327.
https://doi.org/10.1182/blood-2024-208818
Published: 2024
Journal Articles

Prognostic Significance of TP53 Mutations in Lymphoplasmacytic Lymphoma

Anath Lionel, Sherif Seif, Xiaowen Sun, Lei Feng, Lorenzo Gensini, Bria Gabriel, Lauren S. Lewis, Hima Bansal, Melody R. Becnel, Mahmoud R. Gaballa, Hans C. Lee, Oren Pasvolsky, Krina K. Patel, J Christine Ye, Keyur P. Patel, Donna M. Weber, Robert Z. Orlowski, Sheeba K. Thomas
Journal: Blood
Blood (2024) 144 (Supplement 1): 3024.
https://doi.org/10.1182/blood-2024-211193
Published: 2024
Journal Articles

Characterization of Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma Using Single Cell Transcriptomic Analysis

Minghao Dang, Sherif Seif, Maria Jose Acevedo-Calado, Linghua Wang, Bria Gabriel, Lauren S. Lewis, Lorenzo Gensini, Hima Bansal, Melody R. Becnel, Mahmoud R. Gaballa, Hans C. Lee, Oren Pasvolsky, Krina K. Patel, Donna M. Weber, J Christine Ye, Robert Z. Orlowski, Sheeba K. Thomas
Journal: Blood
Blood (2024) 144 (Supplement 1): 1584.
https://doi.org/10.1182/blood-2024-208915
Published: 2024
Journal Articles

A Cell Surface Heat Shock Protein 70 (csHSP70)×CD3 Bispecific T-Cell Engaging Antibody Exhibits Anti-Tumor Efficacy in Pre-Clinical T-Cell Lymphoma and Multiple Myeloma Models

Upasana Ray, Richard J. Jones, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 1598.
https://doi.org/10.1182/blood-2024-211621
Published: 2024
Journal Articles

Unveiling Clinical Potential: Exploring Cytogenomic Aberrations through Optical Genomic Mapping in Multiple Myeloma

J Christine Ye, Guilin Tang, Oren Pasvolsky, Melody R. Becnel, Mahmoud R. Gaballa, Krina K. Patel, Hans C. Lee, Sheeba K. Thomas, Donna M. Weber, Pei Lin, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 1971.
https://doi.org/10.1182/blood-2024-212346
Published: 2024
Journal Articles

Outcomes of Patients with Multiple Myeloma with Deletion 1p Following Autologous Stem Cell Transplant

Oren Pasvolsky, Denái R. Milton, Mark R. Tanner, Qaiser Bashir, Samer A. Srour, Neeraj Y. Saini, Paul Lin, Ashka Patel, Hina N. Khan, Jeremy Ramdial, Yago Nieto, Guilin Tang, Asad Haider, Yosra M. Aljawai, Saqib Ahmed, Partow Kebriaei, Hans C. Lee, Christine Ye, Krina K. Patel, Sheeba K. Thomas, Robert Z. Orlowski, Richard E. Champlin, Elizabeth J. Shpall, Muzaffar H. Qazilbash
Journal: Blood
Blood (2024) 144 (Supplement 1): 3344.
https://doi.org/10.1182/blood-2024-203700
Published: 2024
Journal Articles

Impact of Ethnicity on Long Term Outcomes of High-Dose Chemotherapy and Upfront Autologous Hematopoietic Stem Cell Transplantation in Patients with Multiple Myeloma

Frances N. Cervoni Curet, Roland L. Bassett, Oren Pasvolsky, Abdullah Faisal Deen, Mark R. Tanner, Qaiser Bashir, Samer A. Srour, Neeraj Y. Saini, Jeremy Ramdial, Yago Nieto, Hans C. Lee, Krina K. Patel, Partow Kebriaei, Warren B. Fingrut, Portia Smallbone, Melody R. Becnel, Mahmoud R. Gaballa, Sheeba K. Thomas, J Christine Ye, Robert Z. Orlowski, Richard E. Champlin, Elizabeth J. Shpall, Muzaffar H. Qazilbash
Journal: Blood
Blood (2024) 144 (Supplement 1): 5154.
https://doi.org/10.1182/blood-2024-203824
Published: 2024
Journal Articles

The Anti-BCMA Antibody-Drug Conjugate Hdp-101 with a Novel Amanitin Payload Shows Promising Initial First in Human Results in Relapsed Multiple Myeloma

Robert Z. Orlowski, Shambavi Richard, Jonathan L. Kaufman, Sebastian Grosicki, Istvan Takacs, Andras Strassz, Andreas Martin Pahl, Michael Kulke, Thorsten Michael, Anette Last, Hajnalka Szaboki, Frank Richard, Oliver Schönborn-Kellenberger, Marc S. Raab
Journal: Blood
Blood (2024) 144 (Supplement 1): 3381.
https://doi.org/10.1182/blood-2024-210088
Published: 2024
Journal Articles

Association of Social Determinants of Health Status (SDOH) and Ethnicity with Survival in Multiple Myeloma Patients

Christen M. Dillard, Ashwath Gurumurthi, Hans C. Lee, Sheeba K. Thomas, Donna M. Weber, Robert Z. Orlowski, Muzaffar H. Qazilbash, Krina K. Patel, Michelle A.T. Hildebrandt
Journal: Blood
Blood (2024) 144 (Supplement 1): 3764.
https://doi.org/10.1182/blood-2024-194868
Published: 2024
Journal Articles

Personalized Neoantigen Peptide Vaccine with or without Lenalidomide for Patients with Intermediate or High Risk Smoldering Multiple Myeloma (SMM) to Prevent Progression to Multiple Myeloma (MM)

Krina K. Patel, Elisabet E. Manasanch, Hans C. Lee, J Christine Ye, Sheeba K. Thomas, Donna M. Weber, Melody R. Becnel, Mahmoud R. Gaballa, Hima Bansal, Zuzana Berkova, Sattva S. Neelapu, Cara L Haymaker, Minghao Dang, Linghua Wang, Greg Lizee, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 4737.
https://doi.org/10.1182/blood-2024-205663
Published: 2024
Journal Articles

Isatuximab in Relapsed AL Amyloidosis: Results of a Prospective Phase II Trial (SWOG S1702)

Terri L. Parker, Adam Rosenthal, Vaishali Sanchorawala, Heather J. Landau, Erica L. Campagnaro, Prashant Kapoor, Natalia Neparidze, Saulius Girnius, Patrick Hagen, Emma C. Scott, Antje Hoering, Brian G.M. Durie, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 3378.
https://doi.org/10.1182/blood-2024-208341
Published: 2024
Journal Articles

A Phase III Randomized Trial for Frail Newly Diagnosed Multiple Myeloma Patients Comparing Bortezomib- Lenalidomide-Dexamethasone (VRd-Lite followed by Len maintenance) with Daratumumab-Lenalidomide- Dexamethasone (DRd followed by Len+/- Dara Maintenance): SWOG S2209

Sikander Ailawadhi, Antje Hoering, J Christine Ye, Brea Lipe, Thomas R. Chauncey, Krisstina Gowin, David Calverley, Sarah A. Holstein, Erica L. Campagnaro, Adam Rosenthal, Jack Aiello, Saad Z. Usmani, Vincent Rajkumar, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 3381.3.
https://doi.org/10.1182/blood-2024-209626
Published: 2024
Journal Articles

Conditioning with Busulfan + Melphalan Versus Single-Agent Melphalan for Patients with Multiple Myeloma Receiving Autologous Stem Cell Transplantation: A Propensity Score-Matched Analysis

Romil Patel, Denái R. Milton, Mark R. Tanner, Qaiser Bashir, Samer A. Srour, Neeraj Y. Saini, Paul Lin, Jeremy Ramdial, Yago Nieto, Hans C. Lee, Krina K. Patel, Mahmoud R. Gaballa, Guilin Tang, Yosra M. Aljawai, Partow Kebriaei, Sheeba K. Thomas, Robert Z. Orlowski, Richard E. Champlin, Elizabeth J. Shpall, Muzaffar H. Qazilbash, Oren Pasvolsky
Journal: Blood
Blood (2024) 144 (Supplement 1): 7019.
https://doi.org/10.1182/blood-2024-203529
Published: 2024
Journal Articles

Second Line Treatment in Patients with Multiple Myeloma Progressing after Bortezomib, Lenalidomide, Dexamethasone Induction, Autologous Transplant and Lenalidomide Maintenance

Oren Pasvolsky, Denái R. Milton, Mark R. Tanner, Qaiser Bashir, Samer A. Srour, Neeraj Y. Saini, Paul Lin, Umer R. Siddiqui, Hina N. Khan, Jeremy Ramdial, Yago Nieto, Guilin Tang, Kiran Lakhani, Yosra M. Aljawai, Partow Kebriaei, Hans C. Lee, Krina K. Patel, Sheeba K. Thomas, Robert Z. Orlowski, Elizabeth J. Shpall, Richard E. Champlin, Muzaffar H. Qazilbash
Journal: Blood
Blood (2024) 144 (Supplement 1): 7018.
https://doi.org/10.1182/blood-2024-203404
Published: 2024
Journal Articles

Isatuximab, Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRd) in Patients with Newly Diagnosed Multiple Myeloma (NDMM): Analyses of Minimal Residual Disease (MRD) Negativity Dynamics in the Phase 3 Imroz Study

Robert Z. Orlowski, Meletios-Athanasios Dimopoulos, Xavier Leleu, Zhuogang Liu, Tadao Ishida, Roman Hajek, Ivan Špička, Joanna Romejko-Jarosinska, Vladimir I. Vorobyev, Britta Besemer, Sevgi Beşışık, Pawel Robak, Hartmut Goldschmidt, Thomas Martin, Mohamad Mohty, Sandrine Macé, Ercem Kodas, Christina Tekle, Andrea Shafer, Philippe Moreau
Journal: Blood
Blood (2024) 144 (Supplement 1): 770.
https://doi.org/10.1182/blood-2024-203818
Published: 2024
Journal Articles

Single-Cell Multi-Omic Profiling of Patients with BCMA-Targeted Therapy Identifies Molecular and Cellular Factors Associated with Responsiveness and Treatment Effects

Minghao Dang, Hans C. Lee, Hima Bansal, Maria Acevedo-Calado, Li Qin, Wei Tan, Luz Yurany Moreno Rueda, David Berrios, Krina K. Patel, Pei Lin, Sheeba K. Thomas, Donna M. Weber, Linghua Wang, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 767.
https://doi.org/10.1182/blood-2024-204313
Published: 2024
Journal Articles

Fostering Collaborative Care in Multiple Myeloma: An Update on the Impact of Holistic Education on Decision-Making with Antibody and CAR-T Platforms

Carmine Deluca, Robert Z. Orlowski, Jennifer M. Ahlstrom, Beth M. Faiman, Irene Ghobrial, Michael Beyer, Marina Wanes, Abigail Brugger
Journal: Blood
Blood (2024) 144 (Supplement 1): 7961.
https://doi.org/10.1182/blood-2024-211443
Published: 2024