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Journal Articles

Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma

Nikolaos Trasanidis, Alexia Katsarou, Kanagaraju Ponnusamy, Yao-An Shen, Ioannis V. Kostopoulos, Bien Bergonia, Keren Keren, Paudel Reema, Xiaolin Xiao, Richard M. Szydlo, Pierangela M. R. Sabbattini, Irene A. G. Roberts, Holger W. Auner, Kikkeri N. Naresh, Aristeidis Chaidos, Tian-Li Wang, Luca Magnani, Valentina S. Caputo, Anastasios Karadimitris

Blood (2022) 139 (13): 1939–1953.

https://doi.org/10.1182/blood.2021014391

Published: 2022

Includes: Supplemental data

Journal Articles

Haemopoietic Stem Cell Transplantation for Diamond Blackfan Anaemia Leads to Early and Sustained Engraftment with Good Long-Term Outcomes, but Has an Increased Risk of Gut Toxicity and Lung GvHD

Farah O'Boyle, PhD, Anne Bradshaw, Richard M Szydlo, Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath

Blood (2016) 128 (22): 2679.

https://doi.org/10.1182/blood.V128.22.2679.2679

Published: 2016

Journal Articles

Preconditioning Neutropenia Is a Key Prognostic Factor in Allogeneic Hematopoietic Cell Transplantation for High Risk Acute Myeloid Leukemia

Philippa J Rohman, Richard M Szydlo, Emily Hobbs, Renuka Palanicawandar, Belen Sevillano, Silvia Monsalvo, Andrew Innes, Edward J Kanfer, Dragana Milojkovic, Ian H Gabriel, Christian Jakob, Donald Macdonald, Aristeidis Chaidos, Anastasios Karadimitris, Jane F Apperley, Eduardo Olavarria, Jiří Pavlů

Blood (2016) 128 (22): 3411.

https://doi.org/10.1182/blood.V128.22.3411.3411

Published: 2016

Journal Articles

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Matched and Single Antigen Mismatched Unrelated Bone Marrow Transplantation in Haemoglobinopathies Is Feasible and Leads to Early and Sustanined Engraftment with No Long-Term Toxicity or GvHD

Farah O'Boyle, PhD, Leena Karnik, MD FRCPath, MBBS,, Anne Bradshaw, Richard M Szydlo, Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath

Blood (2016) 128 (22): 2468.

https://doi.org/10.1182/blood.V128.22.2468.2468

Published: 2016

Journal Articles

Impact of Nutrition on Non-Relapse Mortality and Acute Graft Versus Host Disease during Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

Julie Beckerson, Richard M Szydlo, Mary Hickson, Catriona E Mactier, Andrew Innes, Ian H Gabriel, Renuka Palanicawandar, Edward J Kanfer, Donald Macdonald, Dragana Milojkovic, Amin Rahemtulla, Aristeidis Chaidos, Anastasios Karadimitris, Eduardo Olavarria, Jane F. Apperley, MD, Jiří Pavlů

Blood (2016) 128 (22): 2226.

https://doi.org/10.1182/blood.V128.22.2226.2226

Published: 2016

Journal Articles

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Related Transplantation in β Thalassaemia Major Leads to Early and Sustained Engraftment with Low Incidence of VOD and GvHD

Farah O'Boyle, PhD, Leena Karnik, MD FRCPath, MBBS,, Anne Bradshaw, Richard M Szydlo, Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath

Blood (2016) 128 (22): 1283.

https://doi.org/10.1182/blood.V128.22.1283.1283

Published: 2016

Journal Articles

The Intensive Care Trial for Critically Ill Onco-Haematologic Patients: The Need for Response Criteria at 5 Days of Full Treatment to Separate Good Risk Patients and Avoid Futile Intensive Care Interventions

Blood (2016) 128 (22): 5987.

https://doi.org/10.1182/blood.V128.22.5987.5987

Published: 2016

Journal Articles

Excellent Outcome and Good Tolerability of Long-Term Imatinib in Patients with Chronic Myeloid Leukemia (CML)

Simone Claudiani, Nikhita Gupta, BSc, Ji Soo Baik, BSc, Simona Deplano, MDPhD, Renuka Palanicawander, Gareth Gerrard, Alistair G Reid, BSc, PhD, Richard M Szydlo, BSc, PhD, Dragana Milojkovic, Letizia Foroni, Jane F. Apperley, MD

Blood (2015) 126 (23): 2794.

https://doi.org/10.1182/blood.V126.23.2794.2794

Published: 2015

Journal Articles

The Association of Gilbert's Syndrome with Hyperbilirubinaemia Occurring on Any of Imatinib, Dasatinib and Nilotinib in Patients with Chronic Myeloid Leukaemia (CML)

Jeeyune Bahk, BSc, Simone Claudiani, MD, Richard M Szydlo, BSc, PhD, Sarmad Toma, BSc, Faisal Abdillah, BSc, Sandra Hing, BSc, Simona Deplano, MDPhD, Dragana Milojkovic, Jane F Apperley, MD, Letizia Foroni, MD PhD

Blood (2015) 126 (23): 2795.

https://doi.org/10.1182/blood.V126.23.2795.2795

Published: 2015

Journal Articles

Cancer-Selective Targeting of the NF-κB Survival Pathway in Multiple Myeloma with the GADD45β/MKK7 Inhibitor, DTP3

Blood (2015) 126 (23): 868.

https://doi.org/10.1182/blood.V126.23.868.868

Published: 2015

Journal Articles

Clinical Outcome Following Change of Tyrosine Kinase Inhibitor (TKI) According to the Detection of an ABL Kinase Mutation

Renuka Palani, Richard M Szydlo, Jane F. Apperley, Gareth Gerrard, Chrissy Giles, Simona Deplano, Alistair Reid, Letizia Foroni, Dragana Milojkovic

Blood (2014) 124 (21): 4557.

https://doi.org/10.1182/blood.V124.21.4557.4557

Published: 2014

Journal Articles

The Depth Of ‘Complete’ Molecular Response Predicts Molecular Relapse In Chronic Myeloid Leukaemia Patients On Tyrosine Kinase Inhibitor Therapy

Heledd Thomas, BSc, Jane F Apperley, MD, Richard M Szydlo, PhD, Gareth Gerrard, PhD, David Marin, MD, Dragana Milojkovic, PhD, Letizia Foroni, MD

Blood (2013) 122 (21): 5201.

https://doi.org/10.1182/blood.V122.21.5201.5201

Published: 2013

Journal Articles

Dose Interruption/Reduction Of Tyrosine Kinase Inhibitors In The First 3 Months Of Treatment of CML Is Associated With Inferior Early Molecular Responses and Predicts For An Increased Likelihood Of Discontinuation Of The 1st Line Agent

Jane F Apperley, MD, Richard M Szydlo, PhD, Gareth Gerrard, PhD, James R McCue, Jamie Wardle, Richard E Clark, MD, Stephen G O'Brien, Letizia Foroni, MD

Blood (2013) 122 (21): 93.

https://doi.org/10.1182/blood.V122.21.93.93

Published: 2013

Journal Articles

A Novel Splice Site Variant of hOCT-1 and Response to Imatinib.

Jacob Grinfeld, Juan M Alonso-Dominguez, Mary Alikian, Mikel Valgañón, PhD, Georgios Nteliopoulos, PhD, Deborah L. White, PhD, FFSc(RCPA), David Marin, Corinne Hedgley, Stephen O'Brien, Richard E. Clark, MD, Richard M Szydlo, Jane Apperley, John M Goldman, MD, Letizia Foroni, Gareth Gerrard, PhD

Blood (2012) 120 (21): 2555.

https://doi.org/10.1182/blood.V120.21.2555.2555

Published: 2012

Journal Articles

Is Major Molecular Response a Safe Haven Against Blast Crisis in Cml Patients Treated with Imatinib?

Pratap Neelakantan, MRCP, Dragana Milojkovic, Gareth Gerrard, PhD, Letizia Foroni, Jane Apperley, Richard M Szydlo, Alistair Reid, PhD, Marco Bua, Katy Rezvani, MBBS, PhD, MRCP, FRCPath, John M Goldman, MD, David Marin

Blood (2012) 120 (21): 3760.

https://doi.org/10.1182/blood.V120.21.3760.3760

Published: 2012

Journal Articles

Chronic Myeloid Leukemia Patients on Tyrosine Kinase Inhibitor Have Normal T Cell Responses to Vaccination but An Impaired IgM Humoral Response Associated with Loss of Discrete Memory B Cell Subsets,

Blood (2011) 118 (21): 3753.

https://doi.org/10.1182/blood.V118.21.3753.3753

Published: 2011

Journal Articles

Cryopreserved Allogeneic Peripheral Blood Stem Cells Result in Outcome Equivalent to Those of Fresh Infusions Enabling Rational Scheduling of Donations,

Bhuvan Kishore, John Davis, Katayoun Rezvani, MD, PhD, David Marin, Richard M Szydlo, Loaiza Sandra, Giles Chrissy, Aristeidis Chaidos, Edward J Kanfer, Anastasios Karadimitris, Donald H MacDonald, Dragana Milojkovic, MD, Amin Rahemtulla, John M Goldman, Jane F Apperley, MBChB, MD, FRCP, FRCPath, Jiri Pavlu

Blood (2011) 118 (21): 4052.

https://doi.org/10.1182/blood.V118.21.4052.4052

Published: 2011

Journal Articles

Assessment of BCR-ABL1 Transcript Levels At 3 Months Is the Only Requirement for Predicting Outcome for Patients with Chronic Myeloid Leukemia Treated with Imatinib

Dragana Milojkovic, MD, Amr R Ibrahim, Letizia Foroni, MD PhD, Claire Lucas, Gareth Gerrard, PhD, Lihui Wang, Richard M Szydlo, Richard E Clark, Jane F Apperley, MBChB, MD, FRCP, FRCPath, Marco Bua, MD, Jiri Pavlu, Christos Paliompeis, Alistair Reid, PhD, Katy Rezvani, MBBS, PhD, MRCP, FRCPath, John M Goldman, David Marin

Blood (2011) 118 (21): 1680.

https://doi.org/10.1182/blood.V118.21.1680.1680

Published: 2011

Journal Articles

The Majority of Patients Receiving Donor Lymphocyte Infusions for Relapsed Chronic Myeloid Leukemia Remain PCR Positive Despite Maintaining Long-Term Remission,

Andrew J Innes, MBChB, James Lurkins, Richard M Szydlo, Andrea Guerra, Dragana Milojkovic, MD, Jiri Pavlu, Edward J Kanfer, David Marin, Donald MacDonald, Amin Rahemtulla, Sandra Loaiza, Stephanie Kirschke, Katayoun Rezvani, MD, PhD, John Goldman, Jane F Apperley, MBChB, MD, FRCP, FRCPath, Francesco Dazzi

Blood (2011) 118 (21): 4103.

https://doi.org/10.1182/blood.V118.21.4103.4103

Published: 2011

Journal Articles

Elevated Preconditioning Serum Levels of C-Reactive Protein Are Associated with Increased Nonrelapse Mortality and Inferior Survival After Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation

Jiri Pavlu, Katayoun Rezvani, Bhuvan Kishore, Rifca Le Dieu, Joydeep Chakrabartty, Aristeidis Chaidos, Edward J Kanfer, Anastasios Karadimitris, Donald H MacDonald, David Marin, Dragana Milojkovic, MD, Farah O'Boyle, Amin Rahemtulla, David Slade, John M Goldman, Jane F Apperley, MBChB, MD, FRCP, FRCPath, Richard M Szydlo

Blood (2011) 118 (21): 1945.

https://doi.org/10.1182/blood.V118.21.1945.1945

Published: 2011

NARROW

Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma

Haemopoietic Stem Cell Transplantation for Diamond Blackfan Anaemia Leads to Early and Sustained Engraftment with Good Long-Term Outcomes, but Has an Increased Risk of Gut Toxicity and Lung GvHD

Preconditioning Neutropenia Is a Key Prognostic Factor in Allogeneic Hematopoietic Cell Transplantation for High Risk Acute Myeloid Leukemia

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Matched and Single Antigen Mismatched Unrelated Bone Marrow Transplantation in Haemoglobinopathies Is Feasible and Leads to Early and Sustanined Engraftment with No Long-Term Toxicity or GvHD

Impact of Nutrition on Non-Relapse Mortality and Acute Graft Versus Host Disease during Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Related Transplantation in β Thalassaemia Major Leads to Early and Sustained Engraftment with Low Incidence of VOD and GvHD

The Intensive Care Trial for Critically Ill Onco-Haematologic Patients: The Need for Response Criteria at 5 Days of Full Treatment to Separate Good Risk Patients and Avoid Futile Intensive Care Interventions

Excellent Outcome and Good Tolerability of Long-Term Imatinib in Patients with Chronic Myeloid Leukemia (CML)

The Association of Gilbert's Syndrome with Hyperbilirubinaemia Occurring on Any of Imatinib, Dasatinib and Nilotinib in Patients with Chronic Myeloid Leukaemia (CML)

Cancer-Selective Targeting of the NF-κB Survival Pathway in Multiple Myeloma with the GADD45β/MKK7 Inhibitor, DTP3

Clinical Outcome Following Change of Tyrosine Kinase Inhibitor (TKI) According to the Detection of an ABL Kinase Mutation

The Depth Of ‘Complete’ Molecular Response Predicts Molecular Relapse In Chronic Myeloid Leukaemia Patients On Tyrosine Kinase Inhibitor Therapy

Dose Interruption/Reduction Of Tyrosine Kinase Inhibitors In The First 3 Months Of Treatment of CML Is Associated With Inferior Early Molecular Responses and Predicts For An Increased Likelihood Of Discontinuation Of The 1st Line Agent

A Novel Splice Site Variant of hOCT-1 and Response to Imatinib.

Is Major Molecular Response a Safe Haven Against Blast Crisis in Cml Patients Treated with Imatinib?

Chronic Myeloid Leukemia Patients on Tyrosine Kinase Inhibitor Have Normal T Cell Responses to Vaccination but An Impaired IgM Humoral Response Associated with Loss of Discrete Memory B Cell Subsets,

Cryopreserved Allogeneic Peripheral Blood Stem Cells Result in Outcome Equivalent to Those of Fresh Infusions Enabling Rational Scheduling of Donations,

Assessment of BCR-ABL1 Transcript Levels At 3 Months Is the Only Requirement for Predicting Outcome for Patients with Chronic Myeloid Leukemia Treated with Imatinib

The Majority of Patients Receiving Donor Lymphocyte Infusions for Relapsed Chronic Myeloid Leukemia Remain PCR Positive Despite Maintaining Long-Term Remission,

Elevated Preconditioning Serum Levels of C-Reactive Protein Are Associated with Increased Nonrelapse Mortality and Inferior Survival After Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation

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American Society of Hematology

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American Society of Hematology

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