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Journal Articles

The LMO2-LDB1-TAL1 Complex Regulates Transcription Networks in AML Relapse

Blood (2024) 144 (Supplement 1): 2711.

https://doi.org/10.1182/blood-2024-200289

Published: 2024

Journal Articles

Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML

Blood (2024) 144 (1): 84–98.

https://doi.org/10.1182/blood.2024024072

Published: 2024

Includes: Supplemental data

Journal Articles

IDH -mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation

Blood (2024) 143 (18): 1873–1877.

https://doi.org/10.1182/blood.2023023593

Published: 2024

Includes: Supplemental data

Journal Articles

Proteogenomics Coupled with Ex Vivo Profiling for Therapeutic Targeting in AML

Heather C Murray, Anoop K Enjeti, Saumya Samaraweera, Joshua S Brzozowski, Kasey Miller, Richard J D'Andrea, Nicole M Verrills

Blood (2023) 142 (Supplement 1): 4300.

https://doi.org/10.1182/blood-2023-191314

Published: 2023

Journal Articles

Loss of CCAAT‐Enhancer Binding Protein Delta Promotes Acute Myeloid Leukemia Cell Proliferation and Survival By Upregulating Cyclin D1 Expression

Blood (2023) 142 (Supplement 1): 1380.

https://doi.org/10.1182/blood-2023-181946

Published: 2023

Journal Articles

Childhood acute myeloid leukemia shows a high level of germline predisposition

Blood (2021) 138 (22): 2293–2298.

https://doi.org/10.1182/blood.2021012666

Published: 2021

Includes: Supplemental data

Journal Articles

Australian Familial Haematological Cancer Study - Findings from 15 Years of Aggregated Clinical, Genomic and Transcriptomic Data

Christopher N Hahn, PhD, Milena Babic, BMPharBio (Hons), Peter J Brautigan, BSc (Hons), Parvathy Venugopal, PhD MSc, BSc, Kerry Phillips, Julia Dobbins, BSc (Hons), Peer Arts, PhD, Amilia Wee, BSc (Hons), Deepak Singhal, MBBS,MDFRACP,FRCPA, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Jinghua Feng, PhD, Andreas W Schreiber, PhD, Richard J D'Andrea, PhD, Nicola Poplawski, MD, Anna L Brown, PhD, Hamish S Scott, PhD FFSc (RCPA)

Blood (2019) 134 (Supplement_1): 1439.

https://doi.org/10.1182/blood-2019-131686

Published: 2019

Journal Articles

Deleterious Germline Variants, Especially in the DNA Repair Pathway, Are Common in Patients with Non-Related Multiple Cancers, One of Them Being Hematological Malignancy

Blood (2019) 134 (Supplement_1): 1704.

https://doi.org/10.1182/blood-2019-126462

Published: 2019

Journal Articles

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Jason A. Powell, Alexander C. Lewis, Wenying Zhu, John Toubia, Melissa R. Pitman, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Diana Iarossi, Saumya E. Samaraweera, Nik Cummings, Hayley S. Ramshaw, Daniel Thomas, Andrew H. Wei, Angel F. Lopez, Richard J. D’Andrea, Ian D. Lewis, Stuart M. Pitson

Blood (2017) 129 (6): 771–782.

https://doi.org/10.1182/blood-2016-06-720433

Published: 2017

Includes: Supplemental data

Journal Articles

Conditional knockout mice demonstrate function of Klf5 as a myeloid transcription factor

Nur Hezrin Shahrin, Sonya Diakiw, Lindsay A. Dent, Anna L. Brown, Richard J. D’Andrea

Blood (2016) 128 (1): 55–59.

https://doi.org/10.1182/blood-2015-12-684514

Published: 2016

Includes: Supplemental data

Journal Articles

Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies

Blood (2016) 127 (8): 1017–1023.

https://doi.org/10.1182/blood-2015-10-676098

Published: 2016

Includes: Supplemental data

Journal Articles

Gadd45a Loss Enhances MLL Leukemogenesis By Promoting Beta-Catenin Mitochondrial Translocation and Inhibiting Apoptosis

Florida Voli, MSc, Hangyu Yi, BA, Brendon Martinez, BA, Richard J D'Andrea, PhD, Jenny Yingzi Wang, PhD

Blood (2015) 126 (23): 1251.

https://doi.org/10.1182/blood.V126.23.1251.1251

Published: 2015

Journal Articles

Investigation of a Novel Cyclin-Dependent-Kinase (CDK) Inhibitor Cdki-73 As an Effective Treatment Option for MLL-AML

Ka Leung Li, BSc (Hons), Sarah C Bray, PhD, Diana Iarossi, BSc (Hons), Julian Adams, PhD, Longjin Zhong, Ben Noll, BSc (Hons), Muhammed H Rahaman, BSc (Hons), Jennifer Richmond, BSc(Hons), Luen Bik To, MBBS, PhD, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Richard B Lock, PhD, Shudong Wang, PhD, Richard J D'Andrea, PhD

Blood (2015) 126 (23): 1365.

https://doi.org/10.1182/blood.V126.23.1365.1365

Published: 2015

Journal Articles

High Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) Transcriptional Activity Reduces Active Influx of Imatinib and Kinase Inhibition in CML Cells

Jueqiong WANG, PhD, Chung Hoow Kok, PhD, Tamara M Leclercq, PhD, Verity A Saunders, BSc (Hons), Richard J D'Andrea, PhD, Timothy P. Hughes, MD MBBS, FRACP, FRCPA, Deborah L White, PhD FFSc (RCPA)

Blood (2015) 126 (23): 2770.

https://doi.org/10.1182/blood.V126.23.2770.2770

Published: 2015

Journal Articles

Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome

Blood (2015) 126 (23): 1644.

https://doi.org/10.1182/blood.V126.23.1644.1644

Published: 2015

Journal Articles

Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia

Blood (2015) 126 (23): 306.

https://doi.org/10.1182/blood.V126.23.306.306

Published: 2015

Journal Articles

An ENU Mutagenesis Screen of FLT3-ITD Knock-in Mice Identifies Novel Gene Mutations That Lead to an Exacerbated Myeloproliferative Neoplasm

Anna L Brown, PhD, Teresa Sadras, PhD, Grant A Engler, BSc (Hons), Robert Tunningley, PhD, Jennifer Kofler, BSc, Paul J Leo, PhD, Jesse Cheah, BSc, Adrienne Laskowski, BSc, Ann Frazier, PhD, David Stroud, PhD, Michael Ryan, PhD, David Thorburn, PhDFHGSA FFSc(RCPA), D Gary Gilliland, MDPhD, Ian D Lewis, MBBS, PhD, Thomas J Gonda, PhD, Richard J D'Andrea, PhD

Blood (2014) 124 (21): 3591.

https://doi.org/10.1182/blood.V124.21.3591.3591

Published: 2014

Journal Articles

Aberrant Activation of Epidermal Growth Factor Receptor in MPN May Respond to the Kinase Inhibitor Gefitinib

Debora A Casolari, PhD, Diana G Iarossi, BSc (Hons), Carolyn M Butcher, MMedSc(Hons), Sarah C Bray, PhD, Wendy T Parker, PhD, Chris N Hahn, PhD, Susan Branford, PhD, Peter Bardy, MD, Ian D Lewis, MBBS, PhD, Hamish S Scott, PhD, Steven W Lane, MD PhD, David M Ross, MBBS, PhD FRACP, FRCPA, Richard J D'Andrea, PhD

Blood (2014) 124 (21): 1882.

https://doi.org/10.1182/blood.V124.21.1882.1882

Published: 2014

Journal Articles

The Significance of GADD45A Promoter DNA Hypermethylation in AML: Association with IDH1/2 and TET2 Mutation

Michelle Perugini, PhD, Saumya E Samaraweera, PhD, Anna L Brown, PhD, Nik Cummings, BSc, Silke Danner, Ing Soo Tiong, MBChB, Francine E Garrett-Bakelman, MD PhD, Martin P. Carroll, MD, Michael W. Becker, MD, Stephen S. Chung, MD, Christopher Y. Park, MD PhD, Christopher E Mason, PhD, Monica L. Guzman, PhD, Ross L. Levine, MD, Ari M Melnick, MD, Luen Bik To, MBBS, PhD, Andrew H Wei, MBBS, PhD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD

Blood (2014) 124 (21): 69.

https://doi.org/10.1182/blood.V124.21.69.69

Published: 2014

Journal Articles

Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes

Kyaw Zeya Maung, BSc, James X Gray, MD PhD, Paul J Leo, PhD, Mahmoud Bassal, BSc, Anna L Brown, PhD, Sarah C Bray, PhD, Ing Soo Tiong, MBChB, Chung H Kok, PhD, Andrew Deans, PhD, Mhairi Marshall, PhD, Brooke Gardiner, PhD, Evgeny A Glazov, PhD, Paula Marlton, MBBS, Devinder Gill, MD, Luen Bik To, MBBS, PhD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD, Thomas J Gonda, PhD

Blood (2014) 124 (21): 698.

https://doi.org/10.1182/blood.V124.21.698.698

Published: 2014

NARROW

The LMO2-LDB1-TAL1 Complex Regulates Transcription Networks in AML Relapse

Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML

IDH -mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation

Proteogenomics Coupled with Ex Vivo Profiling for Therapeutic Targeting in AML

Loss of CCAAT‐Enhancer Binding Protein Delta Promotes Acute Myeloid Leukemia Cell Proliferation and Survival By Upregulating Cyclin D1 Expression

Childhood acute myeloid leukemia shows a high level of germline predisposition

Australian Familial Haematological Cancer Study - Findings from 15 Years of Aggregated Clinical, Genomic and Transcriptomic Data

Deleterious Germline Variants, Especially in the DNA Repair Pathway, Are Common in Patients with Non-Related Multiple Cancers, One of Them Being Hematological Malignancy

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Conditional knockout mice demonstrate function of Klf5 as a myeloid transcription factor

Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies

Gadd45a Loss Enhances MLL Leukemogenesis By Promoting Beta-Catenin Mitochondrial Translocation and Inhibiting Apoptosis

Investigation of a Novel Cyclin-Dependent-Kinase (CDK) Inhibitor Cdki-73 As an Effective Treatment Option for MLL-AML

High Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) Transcriptional Activity Reduces Active Influx of Imatinib and Kinase Inhibition in CML Cells

Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome

Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia

An ENU Mutagenesis Screen of FLT3-ITD Knock-in Mice Identifies Novel Gene Mutations That Lead to an Exacerbated Myeloproliferative Neoplasm

Aberrant Activation of Epidermal Growth Factor Receptor in MPN May Respond to the Kinase Inhibitor Gefitinib

The Significance of GADD45A Promoter DNA Hypermethylation in AML: Association with IDH1/2 and TET2 Mutation

Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes

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