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Journal Articles

The Role of CMV Antigenic Stimulation in the Pathogenesis of T Cell Large Granular Lymphocytic Leukemia (T-LGL)

Elizabeth Zenni, Bernhard Maier, Sunny Lai, Kitt Paraiso, Alex Chenchik, Magdalena Czader, Utpal P. Dave

Blood (2024) 144 (Supplement 1): 6185.

https://doi.org/10.1182/blood-2024-206393

Published: 2024

Journal Articles

The LMO2-LDB1-TAL1 Complex Regulates Transcription Networks in AML Relapse

Blood (2024) 144 (Supplement 1): 2711.

https://doi.org/10.1182/blood-2024-200289

Published: 2024

Journal Articles

Integrated Genomic Analysis Identifies a Downstream Regulatory Element Oncogenically Activating Hematopoietically Expressed Homeobox ( HHEX ) in ETP-ALL

Utpal P. Davé, Justin Layer, Bernhard Maier, Bryan Venters, Neal Copeland, Nancy Jenkins, Aristotelis Tsirigos, Javier Rodriguez Hernaez, Mircea Ivan

Blood (2023) 142 (Supplement 1): 1403.

https://doi.org/10.1182/blood-2023-182950

Published: 2023

Journal Articles

Strategies to Develop Anti-KIR Mab Lacutamab in Patients with Peripheral T-Cell Lymphoma: Preliminary Monotherapy Clinical Data and Pre-Clinical Combinability Data

Swami P. Iyer, Sabarish R. Ayyappan, Irl Brian Greenwell, Won Seog Kim, Seung Tae Lee, Jin Seok Kim, Won-Sik Lee, Youngwoo Jeon, William Johnson, Utpal P. Dave, Sung-Soo Yoon, Ka-Won Kang, Florent Carrette, Julien Viotti, A.J. Leyco, Marianna Muller, Steven M. Horwitz

Blood (2023) 142 (Supplement 1): 3072.

https://doi.org/10.1182/blood-2023-172537

Published: 2023

Journal Articles

P62SQSTM1 Affects Interacting Substrates MDM2, MDMX and Casein Kinase 1alpha to Yield Protection of Beta-Catenin Along with p53 Silencing for Refractory AML

Justin Layer, Sravanti Rangaraju, Santhosh Pasupuleti, Larry D. Cripe, Hamid Sayar, Katie J Sargent, Jill Weisenbach, Huda S. Salman, G. David Roodman, Linsey Mayo, Reuben Kapur, Utpal P Dave', H. Scott Boswell

Blood (2022) 140 (Supplement 1): 11546–11547.

https://doi.org/10.1182/blood-2022-156329

Published: 2022

Journal Articles

Ldb1 is required for Lmo2 oncogene–induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia

LiQi Li, Apratim Mitra, Kairong Cui, Bin Zhao, Seeyoung Choi, Jan Y. Lee, Daniel B. Stamos, Dalal El-Khoury, Claude Warzecha, Karl Pfeifer, Joyce Hardwick, Keji Zhao, Bryan Venters, Utpal P. Davé, Paul E. Love

Blood (2020) 135 (25): 2252–2265.

https://doi.org/10.1182/blood.2019000794

Published: 2020

Includes: Supplemental data

Journal Articles

Lmo2's Oncogenic Function in T-Cell Leukemia Requires Ldb1

Liqi Li, PhD, Justin H. Layer, PhD, Claude Warzecha, PhD, Rati Tripathi, PhD, Paul Love, MD PhD, Utpal P. Dave, MD

Blood (2015) 126 (23): 3663.

https://doi.org/10.1182/blood.V126.23.3663.3663

Published: 2015

Journal Articles

Comprehensive Hybrid Capture-Based Genomic Profiling of T-Cell Leukemias and Lymphomas Reveals Targetable JAK1 and JAK3 Co-Existing Mutations

Utpal P. Dave, MD, Norma Palma, PhD, Kai Wang, MDPhD, Nishitha M Reddy, M.B.B.S., Siraj Ali, MDPhD, Rati Tripathi, PhD, Allison Greenplate, BS, Jonathan Michael Irish, PhD, Derya Unutmaz, MD, Phil J Stephens, PhD, Vincent A. Miller, MD

Blood (2014) 124 (21): 1672.

https://doi.org/10.1182/blood.V124.21.1672.1672

Published: 2014

Journal Articles

Hhex Is a Critical Gene In The Development Of Normal and Malignant Lymphoid Cells

Charnise Goodings, Stephen B. Smith, PhD, Elizabeth Mathias, Elizabeth Smith, Rati Tripathi, Natalina E Elliott, Susan Cleveland, PhD, Utpal P. Dave, MD, Yang Du, PhD

Blood (2013) 122 (21): 3788.

https://doi.org/10.1182/blood.V122.21.3788.3788

Published: 2013

Journal Articles

Therapeutic Utility of PI3Kγ Inhibition in Leukemogenesis and Tumor Cell Survival

Thomas Diacovo, MD, Dosh Whye, Evgeni Efimenko, Jianchung Chen, Valeria Tosello, PhD, Kim De Keersmaecker, PhD, Adam Kashishian, Mary Ann Thompson, MD, PhD, Mireia Castillo, MD, Carlos Cordon-Cardo, MD, PhD, Utpal P. Dave, MD, Adolfo A. Ferrando, MD, PhD, Brian J. Lannutti, PhD, Prem Subramaniam

Blood (2012) 120 (21): 1492.

https://doi.org/10.1182/blood.V120.21.1492.1492

Published: 2012

Journal Articles

Enforced E47 Expression Has Differential Effects on Lmo2-Induced T-Cell Leukemia

Charnise Goodings, Utpal P. Dave, MD

Blood (2011) 118 (21): 4637.

https://doi.org/10.1182/blood.V118.21.4637.4637

Published: 2011

Journal Articles

Cooperating Oncogenes and Their Targets in LMO2-Induced T-Cell Leukemia

Stephen B. Smith, PhD, Rati Tripathi, Susan Cleveland, PhD, Elizabeth Mathias, Andrew Yi, Charles G Mullighan, MBBS, MD, FRACP, FRCPA, MSc, James R. Downing, MD, Neal G. Copeland, Nancy A Jenkins, Utpal P. Dave, MD

Blood (2011) 118 (21): 2458.

https://doi.org/10.1182/blood.V118.21.2458.2458

Published: 2011

Journal Articles

Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia

Georg Aue, Yang Du, Susan M. Cleveland, Stephen B. Smith, Utpal P. Davé, Delong Liu, Marc A. Weniger, Jean Yves Metais, Nancy A. Jenkins, Neal G. Copeland, Cynthia E. Dunbar

Blood (2011) 118 (17): 4674–4681.

https://doi.org/10.1182/blood-2011-04-351528

Published: 2011

Includes: Supplemental data

Journal Articles

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

Natalina E. Elliott, Susan M. Cleveland, Victor Grann, John Janik, Thomas A. Waldmann, Utpal P. Davé

Blood (2011) 118 (14): 3911–3921.

https://doi.org/10.1182/blood-2010-12-319467

Published: 2011

Includes: Supplemental data

Journal Articles

Sox4 Downregulates Pu.1 Gene Expression by Binding to An Upper Regulatory Element of Pu.1, a Mechanism Contributing to Leukemogenesis.

Georg Aue, MD, Yang Du, PhD, Susan Cleveland, Stephen Smith, Utpal P. Dave, MD, Nancy Jenkins, PhD., Neal G. Copeland, PhD., Cynthia Dunbar

Blood (2009) 114 (22): 3979.

https://doi.org/10.1182/blood.V114.22.3979.3979

Published: 2009

Journal Articles

The Role of JAK3 mutations in Adult T-Cell Leukemia/Lymphoma.

Natalina E Elliott, Susan Cleveland, Victor Grann, John E. Janik, Utpal P. Dave, MD

Blood (2009) 114 (22): 1940.

https://doi.org/10.1182/blood.V114.22.1940.1940

Published: 2009

Journal Articles

Murine Leukemias with Insertional Mutations at Lmo2 Are Highly Predicitive of Leukemias Induced Following Gene Therapy in SCID-X1 Patients

Utpal P. Dave, MD, Keiko Akagi, Ph.D., Rati Tripathi, Susan Cleveland, Mary Thompson, Ming Yi, PhD., Robert Stephens, James R. Downing, MD, Nancy Jenkins, PhD., Neal G. Copeland, PhD.

Blood (2008) 112 (11): 4629.

https://doi.org/10.1182/blood.V112.11.4629.4629

Published: 2008

Journal Articles

Lmo2 Induces T-Cell Leukemia with Epigenetic Deregulation of CD4.

Susan Cleveland, Utpal P. Dave, MD

Blood (2008) 112 (11): 3361.

https://doi.org/10.1182/blood.V112.11.3361.3361

Published: 2008

Journal Articles

Leukemia takes center (late) stage

Utpal P. Davé

Blood (2008) 112 (6): 2175–2176.

https://doi.org/10.1182/blood-2008-07-167726

Published: 2008

Journal Articles

Insertional Activation of GLI2 in Adult T-Cell Leukemia/Lymphoma.

Susan M. Cleveland, PhD, Utpal P. Dave, M.D.

Blood (2007) 110 (11): 4149.

https://doi.org/10.1182/blood.V110.11.4149.4149

Published: 2007

NARROW

The Role of CMV Antigenic Stimulation in the Pathogenesis of T Cell Large Granular Lymphocytic Leukemia (T-LGL)

The LMO2-LDB1-TAL1 Complex Regulates Transcription Networks in AML Relapse

Integrated Genomic Analysis Identifies a Downstream Regulatory Element Oncogenically Activating Hematopoietically Expressed Homeobox ( HHEX ) in ETP-ALL

Strategies to Develop Anti-KIR Mab Lacutamab in Patients with Peripheral T-Cell Lymphoma: Preliminary Monotherapy Clinical Data and Pre-Clinical Combinability Data

P62SQSTM1 Affects Interacting Substrates MDM2, MDMX and Casein Kinase 1alpha to Yield Protection of Beta-Catenin Along with p53 Silencing for Refractory AML

Ldb1 is required for Lmo2 oncogene–induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia

Lmo2's Oncogenic Function in T-Cell Leukemia Requires Ldb1

Comprehensive Hybrid Capture-Based Genomic Profiling of T-Cell Leukemias and Lymphomas Reveals Targetable JAK1 and JAK3 Co-Existing Mutations

Hhex Is a Critical Gene In The Development Of Normal and Malignant Lymphoid Cells

Therapeutic Utility of PI3Kγ Inhibition in Leukemogenesis and Tumor Cell Survival

Enforced E47 Expression Has Differential Effects on Lmo2-Induced T-Cell Leukemia

Cooperating Oncogenes and Their Targets in LMO2-Induced T-Cell Leukemia

Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

Sox4 Downregulates Pu.1 Gene Expression by Binding to An Upper Regulatory Element of Pu.1, a Mechanism Contributing to Leukemogenesis.

The Role of JAK3 mutations in Adult T-Cell Leukemia/Lymphoma.

Murine Leukemias with Insertional Mutations at Lmo2 Are Highly Predicitive of Leukemias Induced Following Gene Therapy in SCID-X1 Patients

Lmo2 Induces T-Cell Leukemia with Epigenetic Deregulation of CD4.

Leukemia takes center (late) stage

Insertional Activation of GLI2 in Adult T-Cell Leukemia/Lymphoma.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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